stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Li C et al. | Enhanced performance and interfacial investigation of mineral-based composite phase change materials for thermal energy storage. | 2013 | Sci Rep | pmid:23712069 |
Wu MH et al. | A novel sodium N-fatty acyl amino acid surfactant using silkworm pupae as stock material. | 2014 | Sci Rep | pmid:24651079 |
Lee W et al. | Novel protein acetyltransferase, Rv2170, modulates carbon and energy metabolism in Mycobacterium tuberculosis. | 2017 | Sci Rep | pmid:28250431 |
Viswanathan R et al. | Strained-layer van der Waals epitaxy in a Langmuir-Blodgett film. | 1993 | Science | pmid:8392751 |
Pouget EM et al. | The initial stages of template-controlled CaCO3 formation revealed by cryo-TEM. | 2009 | Science | pmid:19286549 |
KORN ED and GREENBLATT CL | SYNTHESIS OF ALPHA-LINOLENIC ACID BY LEISHMANIA ENRIETTII. | 1963 | Science | pmid:14074842 |
GERSHFELD NL and SHANES AM | Antagonism of veratrine by calcium ion in monolayers of stearic acid. | 1959 | Science | pmid:13658972 |
Roberts L | Beef and chocolate: a partial reprieve. | 1988 | Science | pmid:3375809 |
ROSENBERG MD | Cell guidance by alterations in monomolecular films. | 1963 | Science | pmid:13974905 |
Takamoto DY et al. | Stable ordering in Langmuir-Blodgett films. | 2001 | Science | pmid:11509723 |
Tse AG et al. | A glycophospholipid tail at the carboxyl terminus of the Thy-1 glycoprotein of neurons and thymocytes. | 1985 | Science | pmid:2865810 |
Yavuz B et al. | An overview on dry eye treatment: approaches for cyclosporin a delivery. | 2012 | ScientificWorldJournal | pmid:22619624 |
Liau CP et al. | Preparation and characterization of polyhydroxybutyrate/polycaprolactone nanocomposites. | 2014 | ScientificWorldJournal | pmid:24600329 |
Woo JO et al. | Development of a controlled release of salicylic acid loaded stearic acid-oleic acid nanoparticles in cream for topical delivery. | 2014 | ScientificWorldJournal | pmid:24578624 |
Pan S et al. | Particle formation by supercritical fluid extraction and expansion process. | 2013 | ScientificWorldJournal | pmid:24223031 |
Shah KU and Khan GM | Regulating drug release behavior and kinetics from matrix tablets based on fine particle-sized ethyl cellulose ether derivatives: an in vitro and in vivo evaluation. | 2012 | ScientificWorldJournal | pmid:22649325 |
Agostini F et al. | Supercritical extraction from vinification residues: fatty acids, α-tocopherol, and phenolic compounds in the oil seeds from different varieties of grape. | 2012 | ScientificWorldJournal | pmid:22593706 |
Oriel JD et al. | Comparison of erythromycin stearate and oxytetracycline in the treatment of non-gonococcal urethritis: their efficacy against Chlamydia trachomatis. | 1977 | Scott Med J | pmid:601555 |
Leese GP et al. | Effects of growth hormone treatment on red cell plasma membrane fatty acid constituents in hypopituitary adults. | 2000 | Scott Med J | pmid:11130294 |
Wang L et al. | [Synthesis, characterization and evaluation of octadecyl ester-bonded monolithic column]. | 2005 | Se Pu | pmid:16350795 |