stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Sherrington EJ et al. | Lack of effect of different dietary saturated fatty acids on adipose tissue deposition in the rat. | 1996 | Biochem. Soc. Trans. | pmid:8736816 |
Britten JR et al. | Studies on powder plug formation using a simulated capsule filling machine. | 1996 | J. Pharm. Pharmacol. | pmid:8737048 |
Xiong W et al. | [Hydrothobic constituents of Nyssa sinensis Oliv]. | 1995 | Zhongguo Zhong Yao Za Zhi | pmid:8737471 |
Shu R et al. | [Chemical constituents of Cyclocarya paliurus (Batal.) Iljinsk]. | 1995 | Zhongguo Zhong Yao Za Zhi | pmid:8737472 |
Mansbach CM | The origin of chylomicron phosphatidylcholine in the rat. | 1977 | J. Clin. Invest. | pmid:874099 |
Veit M et al. | Cytoplasmic tail length influences fatty acid selection for acylation of viral glycoproteins. | 1996 | Biochem. J. | pmid:8761467 |
Schmidt-Weber CB et al. | Apoptotic cell death in activated monocytes following incorporation of clodronate-liposomes. | 1996 | J. Leukoc. Biol. | pmid:8773585 |
Zakhariv OIa and Ianovich VG | [The utilization of [9,10-(3)H] stearic and [1-(14)C] linolenic acids in the in-vitro synthesis of lipids in ruminant tissues]. | 1995 Jul-Aug | Zh. Evol. Biokhim. Fiziol. | pmid:8779280 |
Hughes TA et al. | Comparative lipoprotein metabolism of myristate, palmitate, and stearate in normolipidemic men. | 1996 | Metab. Clin. Exp. | pmid:8781298 |
Negash S et al. | Phosphorylation of phospholamban by cAMP-dependent protein kinase enhances interactions between Ca-ATPase polypeptide chains in cardiac sarcoplasmic reticulum membranes. | 1996 | Biochemistry | pmid:8784178 |
Mastronicolis SK et al. | Diversity of the polar lipids of the food-borne pathogen Listeria monocytogenes. | 1996 | Lipids | pmid:8784744 |
Reverey H et al. | Differential fatty acid selection during biosynthetic S-acylation of a transmembrane protein (HEF) and other proteins in insect cells (Sf9) and in mammalian cells (CV1). | 1996 | J. Biol. Chem. | pmid:8798573 |
Kirsch AJ et al. | Effects of diode laser welding with dye-enhanced glue on tensile strength of sutures commonly used in urology. | 1996 | Lasers Surg Med | pmid:8833285 |
Pai T and Yeh YY | Stearic acid unlike shorter-chain saturated fatty acids is poorly utilized for triacylglycerol synthesis and beta-oxidation in cultured rat hepatocytes. | 1996 | Lipids | pmid:8835403 |
Gotoh N et al. | Inhibition of oxidation of low density lipoprotein by vitamin E and related compounds. | 1996 | Free Radic. Res. | pmid:8845913 |
Shetty HU et al. | Identification of two molecular species of rat brain phosphatidylcholine that rapidly incorporate and turn over arachidonic acid in vivo. | 1996 | J. Neurochem. | pmid:8858956 |
Uchida T et al. | Microencapsulation of ovalbumin in poly(lactide-co-glycolide) by an oil-in-oil (o/o) solvent evaporation method. | 1996 Sep-Oct | J Microencapsul | pmid:8864988 |
Murkovic M et al. | Variability of fatty acid content in pumpkin seeds (Cucurbita pepo L.). | 1996 | Z Lebensm Unters Forsch | pmid:8873459 |
Wargo DJ and Drennen JK | Near-infrared spectroscopic characterization of pharmaceutical powder blends. | 1996 | J Pharm Biomed Anal | pmid:8877847 |
Peck MD et al. | Fatty acid unsaturation increases expression and capping of murine lymphocyte CD44 and CD45. | 1996 | Nutrition | pmid:8878171 |