stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Nakagawa H et al. | Evaluation of infrared-reflection absorption spectroscopy measurement and locally weighted partial least-squares for rapid analysis of residual drug substances in cleaning processes. | 2012 | Anal. Chem. | pmid:22449097 |
Hasegawa T et al. | Molecular orientation analysis of a single-monolayer Langmuir-Blodgett film on a thin glass plate by infrared multiple-angle incidence resolution spectrometry. | 2006 | Anal. Chem. | pmid:16536405 |
Yoo HJ and HÃ¥kansson K | Determination of double bond location in fatty acids by manganese adduction and electron induced dissociation. | 2010 | Anal. Chem. | pmid:20704384 |
Nyadong L et al. | Combining two-dimensional diffusion-ordered nuclear magnetic resonance spectroscopy, imaging desorption electrospray ionization mass spectrometry, and direct analysis in real-time mass spectrometry for the integral investigation of counterfeit pharmaceuticals. | 2009 | Anal. Chem. | pmid:19453162 |
Boiret M et al. | Setting local rank constraints by orthogonal projections for image resolution analysis: application to the determination of a low dose pharmaceutical compound. | 2015 | Anal. Chim. Acta | pmid:26388474 |
Matharu Z et al. | Langmuir-Blodgett film based on MEH-PPV for cholesterol biosensor. | 2009 | Anal. Chim. Acta | pmid:19185127 |
Dillon R et al. | Development of a novel LC/MS method to quantitate cellular stearoyl-CoA desaturase activity. | 2008 | Anal. Chim. Acta | pmid:18790132 |
Saerens L et al. | Validation of an in-line Raman spectroscopic method for continuous active pharmaceutical ingredient quantification during pharmaceutical hot-melt extrusion. | 2014 | Anal. Chim. Acta | pmid:24331054 |
Kessler W et al. | Using scattering and absorption spectra as MCR-hard model constraints for diffuse reflectance measurements of tablets. | 2009 | Anal. Chim. Acta | pmid:19427467 |
Duong CT and Roper MG | A microfluidic device for the automated derivatization of free fatty acids to fatty acid methyl esters. | 2012 | Analyst | pmid:22166918 |