stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen Y et al. | A new method to obtain Fourier transform infrared spectra free from water vapor disturbance. | 2010 | Appl Spectrosc | pmid:20925991 |
| Mukherjee S et al. | Stearic acid delivery to corneum from a mild and moisturizing cleanser. | 2010 | J Cosmet Dermatol | pmid:20883293 |
| Salem HF | Sustained-release progesterone nanosuspension following intramuscular injection in ovariectomized rats. | 2010 | Int J Nanomedicine | pmid:21187946 |
| Rawat MK et al. | Effect of lipid matrix on repaglinide-loaded solid lipid nanoparticles for oral delivery. | 2010 | Ther Deliv | pmid:22816120 |
| Legrand P and Rioux V | The complex and important cellular and metabolic functions of saturated fatty acids. | 2010 | Lipids | pmid:20625935 |
| Patra S et al. | In vitro evaluation of domperidone mouth dissolving tablets. | 2010 | Indian J Pharm Sci | pmid:21969764 |
| Zornetzer GA et al. | The length of the bound fatty acid influences the dynamics of the acyl carrier protein and the stability of the thioester bond. | 2010 | Biochemistry | pmid:20014832 |
| Akpa MM et al. | Inhibition of insulin and T3-induced fatty acid synthase by hexanoate. | 2010 | Lipids | pmid:20811782 |
| Hodson L et al. | Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? | 2010 | Am. J. Physiol. Endocrinol. Metab. | pmid:20628024 |
| Lin YK et al. | Combination of calcipotriol and methotrexate in nanostructured lipid carriers for topical delivery. | 2010 | Int J Nanomedicine | pmid:20309398 |
| Shen J et al. | Thiolated nanostructured lipid carriers as a potential ocular drug delivery system for cyclosporine A: Improving in vivo ocular distribution. | 2010 | Int J Pharm | pmid:20934499 |
| Renaville B et al. | Plasma and follicular fluid fatty acid profiles in dairy cows. | 2010 | Reprod. Domest. Anim. | pmid:19055554 |
| Seerapu S and Srinivasan BP | Development and Validation of RP-HPLC Method for the Estimation of Ivabradine Hydrochloride in Tablets. | 2010 | Indian J Pharm Sci | pmid:21695008 |
| Kharia AA et al. | Design and optimization of floating drug delivery system of acyclovir. | 2010 | Indian J Pharm Sci | pmid:21694992 |
| Varshosaz J et al. | Colon delivery of budesonide using solid dispersion in dextran for the treatment and secondary prevention of ulcerative colitis in rat. | 2010 | Int J Prev Med | pmid:21566772 |
| Alizadeh M et al. | The effect of hypocaloric diet enriched in legumes with or without L-arginine and selenium on anthropometric measures in central obese women. | 2010 | J Res Med Sci | pmid:21526106 |
| Araújo J et al. | Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications. | 2010 | Int J Pharm | pmid:20362042 |
| Bender K et al. | Metabolite concentrations in follicular fluid may explain differences in fertility between heifers and lactating cows. | 2010 | Reproduction | pmid:20385782 |
| Pedersen PJ et al. | Liposomal formulation of retinoids designed for enzyme triggered release. | 2010 | J. Med. Chem. | pmid:20405849 |
| Liew CV et al. | In-line quantification of drug and excipients in cohesive powder blends by near infrared spectroscopy. | 2010 | Int J Pharm | pmid:19922776 |
| Harvey KA et al. | Long-chain saturated fatty acids induce pro-inflammatory responses and impact endothelial cell growth. | 2010 | Clin Nutr | pmid:19926177 |
| Zhou Q et al. | Improving powder flow properties of a cohesive lactose monohydrate powder by intensive mechanical dry coating. | 2010 | J Pharm Sci | pmid:19795479 |
| Uchimoto T et al. | Lubrication properties of potential alternative lubricants, glycerin fatty acid esters, to magnesium stearate. | 2010 | Int J Pharm | pmid:19913080 |
| Muro M et al. | A conformation and orientation model of the carboxylic group of fatty acids dependent on chain length in a Langmuir monolayer film studied by polarization-modulation infrared reflection absorption spectroscopy. | 2010 | J Phys Chem B | pmid:20718412 |
| Nouri A et al. | Effect of process control agent on the porous structure and mechanical properties of a biomedical Ti-Sn-Nb alloy produced by powder metallurgy. | 2010 | Acta Biomater | pmid:19815096 |
| Ohwoavworhua FO and Adelakun TA | Non-wood Fibre Production of Microcrystalline Cellulose from Sorghum caudatum: Characterisation and Tableting Properties. | 2010 | Indian J Pharm Sci | pmid:21188036 |
| Akazawa Y et al. | Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis. | 2010 | J. Hepatol. | pmid:20206402 |
| Song HJ et al. | Effect of probiotic Lactobacillus (Lacidofil® cap) for the prevention of antibiotic-associated diarrhea: a prospective, randomized, double-blind, multicenter study. | 2010 | J. Korean Med. Sci. | pmid:21165295 |
| Chen JL et al. | Metabolomics of gastric cancer metastasis detected by gas chromatography and mass spectrometry. | 2010 | World J. Gastroenterol. | pmid:21155010 |
| Kajiro H et al. | Flexible two-dimensional square-grid coordination polymers: structures and functions. | 2010 | Int J Mol Sci | pmid:21152303 |
| Coulon C et al. | Chemical analysis of cellular and extracellular carbohydrates of a biofilm-forming strain Pseudomonas aeruginosa PA14. | 2010 | PLoS ONE | pmid:21151973 |
| Manickam E et al. | Suppressive actions of eicosapentaenoic acid on lipid droplet formation in 3T3-L1 adipocytes. | 2010 | Lipids Health Dis | pmid:20525346 |
| Luan L et al. | [Studies on the chemical constituents of extract with water from Forsythia suspensa]. | 2010 | Zhong Yao Cai | pmid:20575415 |
| Contreras GA et al. | Lipomobilization in periparturient dairy cows influences the composition of plasma nonesterified fatty acids and leukocyte phospholipid fatty acids. | 2010 | J. Dairy Sci. | pmid:20494158 |
| Karande AD et al. | In-line quantification of micronized drug and excipients in tablets by near infrared (NIR) spectroscopy: Real time monitoring of tabletting process. | 2010 | Int J Pharm | pmid:20558264 |
| Kim IS and Oh IJ | Preparation and characterization of stearic acid-pullulan nanoparticles. | 2010 | Arch. Pharm. Res. | pmid:20512475 |
| Wang J et al. | Solid-state interactions of a drug substance and excipients and their impact on tablet dissolution: a thermal-mechanical facilitated process-induced transformation or PIT. | 2010 | J Pharm Sci | pmid:20533436 |
| Karande AD et al. | Calibration sampling paradox in near infrared spectroscopy: a case study of multi-component powder blend. | 2010 | Int J Pharm | pmid:20472048 |
| Akihisa T et al. | Triterpene alcohol and fatty acid composition of shea nuts from seven African countries. | 2010 | J Oleo Sci | pmid:20513968 |
| Kanjanavas P et al. | Purification and characterization of organic solvent and detergent tolerant lipase from thermotolerant Bacillus sp. RN2. | 2010 | Int J Mol Sci | pmid:21152301 |
| Tripathi B and Platel K | Finger millet (Eleucine coracana) flour as a vehicle for fortification with zinc. | 2010 | J Trace Elem Med Biol | pmid:20122580 |
| Pires de Souza FC et al. | In vitro comparison of the radiopacity of cavity lining materials with human dental structures. | 2010 | J Conserv Dent | pmid:20859477 |
| Lyra A et al. | Effect of a multispecies probiotic supplement on quantity of irritable bowel syndrome-related intestinal microbial phylotypes. | 2010 | BMC Gastroenterol | pmid:20849659 |
| Huang WH et al. | Development of liposomal salbutamol sulfate dry powder inhaler formulation. | 2010 | Biol. Pharm. Bull. | pmid:20190418 |
| Shishu VR et al. | Development of taste masked oral formulation of ornidazole. | 2010 | Indian J Pharm Sci | pmid:20838525 |
| Jeong SH and Park K | Simple preparation of coated resin complexes and their incorporation into fast-disintegrating tablets. | 2010 | Arch. Pharm. Res. | pmid:20191352 |
| Gohel MC et al. | Fabrication and Evaluation of Bi-layer Tablet Containing Conventional Paracetamol and Modified Release Diclofenac Sodium. | 2010 | Indian J Pharm Sci | pmid:20838522 |
| Cho KH et al. | Monoacylglycerol (MAG)-oleic acid has stronger antioxidant, anti-atherosclerotic, and protein glycation inhibitory activities than MAG-palmitic acid. | 2010 | J Med Food | pmid:20136442 |
| Phaechamud T et al. | Preparation of Coated Valproic Acid and Sodium Valproate Sustained-release Matrix Tablets. | 2010 | Indian J Pharm Sci | pmid:20838520 |
| Yang X et al. | In vitro skin permeation of hinokitiol loaded in vesicles composed of behenyltrimethylammonium chloride and stearic acid. | 2010 | Drug Dev Ind Pharm | pmid:20141448 |
| Huthmacher C et al. | Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis. | 2010 | BMC Syst Biol | pmid:20807400 |
| Du YZ et al. | Stearic acid grafted chitosan oligosaccharide micelle as a promising vector for gene delivery system: factors affecting the complexation. | 2010 | Int J Pharm | pmid:20170716 |
| Noguchi Y et al. | Ketogenic essential amino acids modulate lipid synthetic pathways and prevent hepatic steatosis in mice. | 2010 | PLoS ONE | pmid:20706589 |
| Maher AC et al. | Women have higher protein content of beta-oxidation enzymes in skeletal muscle than men. | 2010 | PLoS ONE | pmid:20700461 |
| Wang Q et al. | One-Step Synthesis of Monodisperse In-Doped ZnO Nanocrystals. | 2010 | Nanoscale Res Lett | pmid:20672040 |
| Pöllänen E et al. | Power training and postmenopausal hormone therapy affect transcriptional control of specific co-regulated gene clusters in skeletal muscle. | 2010 | Age (Dordr) | pmid:20640546 |
| Gentile CL et al. | Fatty acids regulate CREBh via transcriptional mechanisms that are dependent on proteasome activity and insulin. | 2010 | Mol. Cell. Biochem. | pmid:20607591 |
| Do PT et al. | The influence of fruit load on the tomato pericarp metabolome in a Solanum chmielewskii introgression line population. | 2010 | Plant Physiol. | pmid:20841452 |
| Harvey KA et al. | Oleic acid inhibits stearic acid-induced inhibition of cell growth and pro-inflammatory responses in human aortic endothelial cells. | 2010 | J. Lipid Res. | pmid:20852092 |
| Chitapanarux I et al. | Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. | 2010 | Radiat Oncol | pmid:20444243 |
| Blanco M and Peguero A | Influence of physical factors on the accuracy of calibration models for NIR spectroscopy. | 2010 | J Pharm Biomed Anal | pmid:20044229 |
| Swanson EJ et al. | Phospholipid-stabilized microbubble foam for injectable oxygen delivery. | 2010 | Langmuir | pmid:20873807 |
| Howell AB et al. | Dosage effect on uropathogenic Escherichia coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content: a multicentric randomized double blind study. | 2010 | BMC Infect. Dis. | pmid:20398248 |
| Yasuda A et al. | Self-organizing map analysis using multivariate data from theophylline powders predicted by a thin-plate spline interpolation. | 2010 | J Pharm Sci | pmid:20845452 |
| UÄŸurlu T et al. | Effects of lubricants on binary direct compression mixtures. | 2010 | Drug Discov Ther | pmid:22491169 |
| Shaikh SA et al. | Formulation and evaluation of s-(-)-amlodipine besylate and nebivolol hydrochloride tablets. | 2010 | J Adv Pharm Technol Res | pmid:22247846 |
| Dasu K et al. | Hydrolysis of fluorotelomer compounds leading to fluorotelomer alcohol production during solvent extractions of soils. | 2010 | Chemosphere | pmid:20801485 |
| Tiwari G et al. | Cyclodextrins in delivery systems: Applications. | 2010 | J Pharm Bioallied Sci | pmid:21814436 |
| Moore F et al. | Improving the hardness of dry granulated tablets containing sodium lauryl sulfate. | 2010 | Int J Pharm | pmid:20801204 |
| Chen X et al. | Plasma metabolomics reveals biomarkers of the atherosclerosis. | 2010 | J Sep Sci | pmid:20730840 |
| Shidhaye SS et al. | Buccal drug delivery of pravastatin sodium. | 2010 | AAPS PharmSciTech | pmid:20300898 |
| Horne I et al. | Two conserved Z9-octadecanoic acid desaturases in the red flour beetle, Tribolium castaneum. | 2010 | Gene | pmid:20709164 |
| Ion G et al. | Maternal consumption of canola oil suppressed mammary gland tumorigenesis in C3(1) TAg mice offspring. | 2010 | BMC Cancer | pmid:20205934 |
| Vlachou M et al. | Utilization of hydrophilic swellable polymers as carriers for sustained drug delivery from matrices and three layer tablet systems. | 2010 | Curr Drug Deliv | pmid:20695845 |
| Mas S et al. | Local non-esterified fatty acids correlate with inflammation in atheroma plaques of patients with type 2 diabetes. | 2010 | Diabetes | pmid:20200316 |
| Kurian GA et al. | Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts. | 2010 | Chin Med | pmid:20180993 |
| Mathew M et al. | Elevated plasma free fatty acids increase cardiovascular risk by inducing plasma biomarkers of endothelial activation, myeloperoxidase and PAI-1 in healthy subjects. | 2010 | Cardiovasc Diabetol | pmid:20158910 |
| Hsieh HT et al. | Facile synthesis of silver nanoparticles in CO2-expanded liquids from silver isostearate precursor. | 2010 | Langmuir | pmid:20297774 |
| van den Berg SA et al. | High levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity. | 2010 | Nutr Metab (Lond) | pmid:20346174 |
| Xing Z et al. | Novel ultrasound contrast agent based on microbubbles generated from surfactant mixtures of Span 60 and polyoxyethylene 40 stearate. | 2010 | Acta Biomater | pmid:20226284 |
| Choi JN et al. | Metabolomics revealed novel isoflavones and optimal cultivation time of Cordyceps militaris fermentation. | 2010 | J. Agric. Food Chem. | pmid:20225861 |
| Desando MA et al. | Proton magnetic relaxation and the aggregation of n-octylammonium n-octadecanoate surfactant in deuterochloroform solution. | 2010 | J Colloid Interface Sci | pmid:20223468 |
| Xing Z et al. | The fabrication of novel nanobubble ultrasound contrast agent for potential tumor imaging. | 2010 | Nanotechnology | pmid:20220227 |
| Li Y et al. | Preparation and characterization of coverage-controlled CaCO3 nanoparticles. | 2010 | J Colloid Interface Sci | pmid:20202642 |
| Salbu L et al. | Direct compression behavior of low- and high-methoxylated pectins. | 2010 | AAPS PharmSciTech | pmid:20013080 |
| Romanowicz L and Bańkowski E | Sphingolipids of human umbilical cord vein and their alteration in preeclampsia. | 2010 | Mol. Cell. Biochem. | pmid:20155487 |
| Kordyukova LV et al. | Site-specific attachment of palmitate or stearate to cytoplasmic versus transmembrane cysteines is a common feature of viral spike proteins. | 2010 | Virology | pmid:20006369 |
| Abdel-Mottaleb MM et al. | In vitro drug release mechanism from lipid nanocapsules (LNC). | 2010 | Int J Pharm | pmid:20149853 |
| Taneri F et al. | In vitro and in vivo evaluation of oral tablet formulations prepared with ketoconazole and hydroxypropyl-beta-cyclodextrin. | 2010 | Drug Deliv | pmid:20148713 |
| Wang J et al. | Lubrication in tablet formulations. | 2010 | Eur J Pharm Biopharm | pmid:20096779 |
| Dong J et al. | Cation-controlled crystal growth of silver stearate: cryo-TEM investigation of lithium vs sodium stearate. | 2010 | Langmuir | pmid:20017506 |
| Fu X et al. | A rapid and universal bacteria-counting approach using CdSe/ZnS/SiO2 composite nanoparticles as fluorescence probe. | 2010 | Anal Bioanal Chem | pmid:20016878 |
| Kushner J and Moore F | Scale-up model describing the impact of lubrication on tablet tensile strength. | 2010 | Int J Pharm | pmid:20667504 |
| Zhang LJ et al. | Hot-injection synthesis of highly luminescent and monodisperse CdS nanocrystals using thioacetamide and cadmium source with proper reactivity. | 2010 | J Colloid Interface Sci | pmid:19932894 |
| Imae R et al. | Intracellular phospholipase A1 and acyltransferase, which are involved in Caenorhabditis elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol. | 2010 | Mol. Biol. Cell | pmid:20668164 |
| Su C et al. | A novel assay of cellular stearoyl-CoA desaturase activity of primary rat hepatocytes by HPLC. | 2010 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:20732836 |
| Yoo HJ and HÃ¥kansson K | Determination of double bond location in fatty acids by manganese adduction and electron induced dissociation. | 2010 | Anal. Chem. | pmid:20704384 |
| Yeop Han C et al. | Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation. | 2010 | Diabetes | pmid:19934003 |
| Raeside JI and Christie HL | Diaryl dimers of estradiol and of estrone may be formed as major metabolites by mouse mammary glands. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20875396 |
| Valencia-Chamorro SA et al. | Effect of antifungal hydroxypropyl methylcellulose-lipid edible composite coatings on Penicillium decay development and postharvest quality of cold-stored "Ortanique" mandarins. | 2010 | J. Food Sci. | pmid:21535515 |