stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Haley K et al. | Optimal milk penicillin levels for the treatment of experimentally induced mastitis in cows. | 1981 | Can. J. Comp. Med. | pmid:7340909 |
Sugita M et al. | Studies on glycosphingolipids of fresh-water bivalves. VI. Isolation and chemical characterization of neutral glycosphingolipids from spermatozoa of the fresh-water bivalve, Hyriopsis schlegelii. | 1981 | J. Biochem. | pmid:7338520 |
Yue KT et al. | Effect of glucose on plasma concentrations of individual non-esterified fatty acids of non-diabetic and insulin-independent diabetic men. | 1981 | Postgrad Med J | pmid:7335561 |
Cook HW | The influence of trans-acids on desaturation and elongation of fatty acids in developing brain. | 1981 | Lipids | pmid:7329212 |
Loi F and Amati R | [Lead-stearate exposure in a plastic factory in the province of Siena (author's transl)]. | 1981 Sep-Oct | Med Lav | pmid:7322018 |
Bolhuis GK et al. | Interaction of tablet disintegrants and magnesium stearate during mixing I: Effect on tablet disintegration. | 1981 | J Pharm Sci | pmid:7320846 |
Benes B and Bencko V | Content of lipids and esterified fatty acids in the liver of mice exposed to arsenic in drinking water. | 1981 | J Hyg Epidemiol Microbiol Immunol | pmid:7320503 |
Clayton D and Leslie A | The bioavailability of erythromycin stearate versus enteric-coated erythromycin base when taken immediately before and after food. | 1981 | J. Int. Med. Res. | pmid:7319133 |
Eriksson M et al. | Absorption of erythromycin from pediatric suspension in infants and children. | 1981 | Scand. J. Infect. Dis. | pmid:7313575 |
Alam AS and Gregoriades D | Physicochemical properties of magnesium salicylate. | 1981 | J Pharm Sci | pmid:7310674 |
Baker RR and Chang HY | A comparison of lysophosphatidylcholine acyltransferase activities in neuronal nuclei and microsomes isolated from immature rabbit cerebral cortex. | 1981 | Biochim. Biophys. Acta | pmid:7306562 |
Mather LE et al. | Absorption and bioavailability of oral erythromycin. | 1981 | Br J Clin Pharmacol | pmid:7306427 |
Faas FH and Carter WJ | Fatty-acid desaturation and microsomal lipid fatty-acid composition in experimental hyperthyroidism. | 1981 | Biochem. J. | pmid:7305962 |
Teyssier G et al. | [Adult-type respiratory distress syndrome in children. Course of the palmitic acid/stearic acid ratio in tracheal aspirations]. | 1981 | Nouv Presse Med | pmid:7290945 |
Albanese A et al. | [Preparation of patients in diagnostic contrast radiography of the urinary and bile tracts and the large intestine]. | 1981 | Minerva Med. | pmid:7290472 |
Jordan BR and Harwood JL | Fatty acid elongation by a particulate fraction from germinating pea. | 1980 | Biochem. J. | pmid:7283974 |
Walzthöny D et al. | Ice crystals specifically decorate hydrophilic sites on freeze-fractured models membranes. | 1981 | Ultramicroscopy | pmid:7281365 |
Iliopoulou A et al. | Fluorimetric and microbiological assays of erythromycin concentrations in plasma and vaginal washings. | 1981 | Br J Vener Dis | pmid:7272705 |
Davis PJ et al. | Gel to liquid-crystalline transition temperatures of water dispersions of two pairs of positional isomers of unsaturated mixed-acid phosphatidylcholines. | 1981 | Biochemistry | pmid:7260060 |
d'Avila Nunes M | A spin label study of erythrocyte membranes during simulation of freezing. | 1981 | J. Membr. Biol. | pmid:7253007 |
Holub BJ | The suitability of different acyl acceptors as substrates for the acyl-Coa : 2-acyl-sn-glycero-3-phosphorylcholine acyltransferase in rat liver microsomes. | 1981 | Biochim. Biophys. Acta | pmid:7248321 |
Chien JL and Hogan EL | Characterization of two gangliosides of the paragloboside series from chicken skeletal muscle. | 1980 | Biochim. Biophys. Acta | pmid:7236652 |
Naggar VF | An in vitro study of the interaction between diazepam and some antacid or excipients. | 1981 | Pharmazie | pmid:7232481 |
Rosenthal MD | Accumulation of neutral lipids by human skin fibroblasts: differential effects of saturated and unsaturated fatty acids. | 1981 | Lipids | pmid:7219087 |
Smaby JM and Brockman HL | Novel surface phase containing cholesteryl esters. 2. Nonequivalence of cholesteryl arachidonate and those with 18-carbon, cis-unsaturated acyl groups. | 1981 | Biochemistry | pmid:7213606 |
Wenzel DG and Kleoppel JW | Incorporation of saturated and cis- and trans-unsaturated long chain fatty acids in rat myocytes and increased susceptibility to arrhythmias. | 1980 | Toxicology | pmid:7210021 |
Nakagawa H et al. | [Effects of particle size of rifampicin and addition of magnesium stearate on release of rifampicin from hard gelatin capsules (author's transl)]. | 1980 | Yakugaku Zasshi | pmid:7205556 |
Hambleton PL et al. | Dietary fat and exercise conditioning effect on metabolic parameters in the horse. | 1980 | J. Anim. Sci. | pmid:7204274 |
Oriel JD and Ridgway GL | Comparison of erythromycin and oxytetracycline in the treatment of cervical infection by Chlamydia trachomatis. | 1980 | J. Infect. | pmid:7185927 |
Faas FH and Carter WJ | Fatty acid desaturation and microsomal lipid fatty acid composition in experimental hypothyroidism. | 1982 | Biochem. J. | pmid:7181859 |
Iliopoulou A et al. | Should erythromycin dose be altered in haemodialysis patients? | 1982 | Eur. J. Clin. Pharmacol. | pmid:7151848 |
Warner T and Zar JH | Fatty acid composition of brown fat and brain fat of the little brown bat, Myotis lucifugus, during hibernation. | 1982 | Comp. Biochem. Physiol., B | pmid:7151405 |
Lerk CF et al. | Interaction of tablet disintegrants and magnesium stearate during mixing. II. Effect on dissolution rate. | 1982 | Pharm Acta Helv | pmid:7146030 |
Katz AM and Messineo FC | Fatty acid effects on membranes: possible role in the pathogenesis of ischemic myocardial damage. | 1982 | J. Mol. Cell. Cardiol. | pmid:7143451 |
Mroso PV et al. | Solid-state stability of aspirin in the presence of excipients: kinetic interpretation, modeling, and prediction. | 1982 | J Pharm Sci | pmid:7143203 |
Triggs EJ and Ashley JJ | Oral administration of erythromycin stearate: effect of dosage form on plasma levels. | 1978 | Med. J. Aust. | pmid:713930 |
Chen SC et al. | Calorimetric evidence for phase transitions in spin-label lipid bilayers. | 1982 | Biochemistry | pmid:7138849 |
NadtochiÄ VV and BrodskiÄ RA | [Absorption study of 3H-stearic acid in the rat small intestine using electron microscopic autoradiography]. | 1982 | Tsitologiia | pmid:7135486 |
Rosing U et al. | Relative fatty acid composition of serum lecithin in the second half of the normal pregnancy. | 1982 | Gynecol. Obstet. Invest. | pmid:7129232 |
Boyd RD et al. | Oxidation rates of major fatty acids in fasting neonatal pigs. | 1982 | J. Anim. Sci. | pmid:7118744 |
Sanchez J et al. | Lipase-induced alterations of fatty acid synthesis by subcellular fractions from germinating pea (Pisum sativum L.). | 1982 | Biochem. J. | pmid:7115342 |
Townsend LE et al. | In vitro acylation of rat brain myelin proteolipid protein. | 1982 | J. Biol. Chem. | pmid:7107590 |
Huang YS et al. | Tissue lipids in acute acrylamide intoxicated rats. | 1982 | Can J Neurol Sci | pmid:7104883 |
Pritzker KP et al. | Adrenal and hepatic calcium stearate crystal deposits in dogs fed a thiamine-deficient diet. | 1982 | Am. J. Vet. Res. | pmid:7103233 |
Holub BJ | The relative deacylation of different molecular species of endogenous phosphatidylethanolamine in rat liver microsomes by phospholipase activity. | 1982 | Biochim. Biophys. Acta | pmid:7093298 |
Josefsson K et al. | Dose-related pharmacokinetics after oral administration of a new formulation of erythromycin base. | 1982 | Br J Clin Pharmacol | pmid:7082537 |
Lehmann J and McGill M | Biochemical and ultrastructural alterations in platelets, reticulocytes, and lymphocytes from rats fed vitamin E-deficient diets. | 1982 | J. Lipid Res. | pmid:7077144 |
Bridges CD et al. | Vitamin A in human eyes: amount, distribution, and composition. | 1982 | Invest. Ophthalmol. Vis. Sci. | pmid:7076416 |
Katz AM et al. | Fatty acid effects on calcium influx and efflux in sarcoplasmic reticulum vesicles from rabbit skeletal muscle. | 1982 | Biochim. Biophys. Acta | pmid:7074105 |
Woodward H et al. | Isolation, purification, and properties of respiratory mucus glycoproteins. | 1982 | Biochemistry | pmid:7074033 |