stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Arteriosclerosis D001161 86 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Olfaction Disorders D000857 17 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Amnesia D000647 12 associated lipids
Alzheimer Disease D000544 76 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Adenoma D000236 40 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Fodorová M et al. Structural features of lipid A of Rickettsia typhi. 2011 Acta Virol. pmid:21434703
Ropero J et al. Near-infrared chemical imaging slope as a new method to study tablet compaction and tablet relaxation. 2011 Appl Spectrosc pmid:21396195
Junk MJ et al. DEER in biological multispin-systems: a case study on the fatty acid binding to human serum albumin. 2011 J. Magn. Reson. pmid:21450500
Franch-Lage F et al. Fast assessment of the surface distribution of API and excipients in tablets using NIR-hyperspectral imaging. 2011 Int J Pharm pmid:21419207
Xu QC et al. Enhanced photocatalytic activity of C-N-codoped TiO2 films prepared via an organic-free approach. 2011 J. Hazard. Mater. pmid:21316842
Zhou QT et al. Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approach. 2011 J Pharm Sci pmid:21455980
Sheikh KA et al. Influence of hydration state and homologue composition of magnesium stearate on the physical chemical properties of liquid paraffin lipogels. 2011 Int J Pharm pmid:21457766
Wang S et al. Insertion of an esterase gene into a specific locust pathogen (Metarhizium acridum) enables it to infect caterpillars. 2011 PLoS Pathog. pmid:21731492
Paczkowski S and Schütz S Post-mortem volatiles of vertebrate tissue. 2011 Appl. Microbiol. Biotechnol. pmid:21720824
Wahjudi PN et al. Turnover of nonessential fatty acids in cardiolipin from the rat heart. 2011 J. Lipid Res. pmid:21957203
Paul D et al. Proteome and membrane fatty acid analyses on Oligotropha carboxidovorans OM5 grown under chemolithoautotrophic and heterotrophic conditions. 2011 PLoS ONE pmid:21386900
Ash MM et al. Phytosterol stearate esters elicit similar responses on plasma lipids and cholesterol absorption but different responses on fecal neutral sterol excretion and hepatic free cholesterol in male Syrian hamsters. 2011 Nutr Res pmid:21840470
Rojas J and Kumar V Comparative evaluation of silicified microcrystalline cellulose II as a direct compression vehicle. 2011 Int J Pharm pmid:21708237
Neji SB et al. Esterification of fatty acid over Tunisian acid activated clay: kinetic study. 2011 J Oleo Sci pmid:21606617
Whitney TR et al. Redberry juniper as a roughage source in lamb feedlot rations: wool and carcass characteristics, meat fatty acid profiles, and sensory panel traits. 2011 Meat Sci. pmid:21570776
Yalcin H et al. Effect of gamma-irradiation on some chemical characteristics and volatile content of linseed. 2011 J Med Food pmid:21548804
Dong Z et al. Preparation and in vitro, in vivo evaluations of norfloxacin-loaded solid lipid nanopartices for oral delivery. 2011 Drug Deliv pmid:21554156
Zhang Y et al. α-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytes. 2011 Lipids Health Dis pmid:21592363
Ting TC et al. Increased lipogenesis and stearate accelerate vascular calcification in calcifying vascular cells. 2011 J. Biol. Chem. pmid:21596756
Man TY et al. Dietary manipulation reveals an unexpected inverse relationship between fat mass and adipose 11β-hydroxysteroid dehydrogenase type 1. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:21406612
Pingali K et al. Evaluation of strain-induced hydrophobicity of pharmaceutical blends and its effect on drug release rate under multiple compression conditions. 2011 Drug Dev Ind Pharm pmid:20942612
Arora G et al. Formulation and evaluation of controlled release matrix mucoadhesive tablets of domperidone using Salvia plebeian gum. 2011 J Adv Pharm Technol Res pmid:22171313
El-Enany NM et al. Spectrofluorimetric determination of sertraline in dosage forms and human plasma through derivatization with 9-fluorenylmethyl chloroformate. 2011 Chem Cent J pmid:21978386
D'Ambrosio DN et al. Distinct populations of hepatic stellate cells in the mouse liver have different capacities for retinoid and lipid storage. 2011 PLoS ONE pmid:21949825
Nurul Syazana MS et al. Antiproliferative effect of methanolic extraction of tualang honey on human keloid fibroblasts. 2011 BMC Complement Altern Med pmid:21943200
Tachibana H Green tea polyphenol sensing. 2011 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:21422740
Singhal A et al. Colon-targeted quercetin delivery using natural polymer to enhance its bioavailability. 2011 Pharmacognosy Res pmid:21731393
Li FQ et al. A novel spray-dried nanoparticles-in-microparticles system for formulating scopolamine hydrobromide into orally disintegrating tablets. 2011 Int J Nanomedicine pmid:21720502
Kumaravelrajan R et al. Development and evaluation of controlled porosity osmotic pump for nifedipine and metoprolol combination. 2011 Lipids Health Dis pmid:21477386
Kordyukova LV et al. Linker and/or transmembrane regions of influenza A/Group-1, A/Group-2, and type B virus hemagglutinins are packed differently within trimers. 2011 Biochim. Biophys. Acta pmid:21420932
Wang L et al. Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations. 2011 AIDS Res Ther pmid:21385339
Salem H et al. Nanosized rods agglomerates as a new approach for formulation of a dry powder inhaler. 2011 Int J Nanomedicine pmid:21383856
Intorre F et al. Differential effect of cheese fatty acid composition on blood lipid profile and redox status in normolipidemic volunteers: a pilot study. 2011 Int J Food Sci Nutr pmid:21591986
Gresback R et al. Combined plasma gas-phase synthesis and colloidal processing of InP/ZnS core/shell nanocrystals. 2011 Nanoscale Res Lett pmid:21711589
Desai D et al. Fatty acid and water-soluble polymer-based controlled release drug delivery system. 2011 J Pharm Sci pmid:21374622
Kulinowski P et al. Magnetic resonance imaging and image analysis for assessment of HPMC matrix tablets structural evolution in USP Apparatus 4. 2011 Pharm. Res. pmid:21181545
Christian F et al. Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes. 2011 J. Biol. Chem. pmid:21177871
Basu BJ and Manasa J Effect of deposition parameters on the wettability and microstructure of superhydrophobic films with hierarchical micro-nano structures. 2011 J Colloid Interface Sci pmid:21864844
Su Z et al. Effect of octreotide-polyethylene glycol(100) monostearate modification on the pharmacokinetics and cellular uptake of nanostructured lipid carrier loaded with hydroxycamptothecine. 2011 Mol. Pharm. pmid:21770405
Petelska AD and Figaszewski ZA The equilibria of phosphatidylcholine-fatty acid and phosphatidylcholine-amine in monolayers at the air/water interface. 2011 Colloids Surf B Biointerfaces pmid:20888195
Laus MN et al. Activation of the plant mitochondrial potassium channel by free fatty acids and acyl-CoA esters: a possible defence mechanism in the response to hyperosmotic stress. 2011 J. Exp. Bot. pmid:20801915
Klein CM and Jenkins TC Docosahexaenoic acid elevates trans-18:1 isomers but is not directly converted into trans-18:1 isomers in ruminal batch cultures. 2011 J. Dairy Sci. pmid:21854940
Waters LJ et al. Controlled microwave processing applied to the pharmaceutical formulation of ibuprofen. 2011 AAPS PharmSciTech pmid:21842309
Corvis Y et al. Physicochemical stability of solid dispersions of enantiomeric or racemic ibuprofen in stearic acid. 2011 J Pharm Sci pmid:21905027
Gao Q et al. Synthesis and characterization of novel amphiphilic copolymer stearic acid-coupled F127 nanoparticles for nano-technology based drug delivery system. 2011 Colloids Surf B Biointerfaces pmid:21906917
Khan FN and Dehghan MH Enhanced bioavailability of atorvastatin calcium from stabilized gastric resident formulation. 2011 AAPS PharmSciTech pmid:21879394
Varshosaz J et al. Lipid nanocapsule-based gels for enhancement of transdermal delivery of ketorolac tromethamine. 2011 J Drug Deliv pmid:22175029
Taylor M and Elhissi AM Predicting the physical properties of tablets from ATR-FTIR spectra using partial least squares regression. 2011 Pharm Dev Technol pmid:20100067
Du YZ et al. Quaternary complexes composed of plasmid DNA/protamine/fish sperm DNA/stearic acid grafted chitosan oligosaccharide micelles for gene delivery. 2011 Int. J. Biol. Macromol. pmid:21035503
Bhattacharjee A et al. Deposition of stearate-oleate rich seed fat in Mangifera indica is mediated by a FatA type acyl-ACP thioesterase. 2011 Phytochemistry pmid:21130480
Bazzini AA et al. Metabolic and miRNA profiling of TMV infected plants reveals biphasic temporal changes. 2011 PLoS ONE pmid:22174812
Masareddy R et al. Development of Orodispersible Tizanidine HCl Tablets Using Spray Dried Coprocessed Exipient Bases. 2011 Indian J Pharm Sci pmid:22707822
Göker M et al. Complete genome sequence of the thermophilic sulfur-reducer Desulfurobacterium thermolithotrophum type strain (BSA(T)) from a deep-sea hydrothermal vent. 2011 Stand Genomic Sci pmid:22675590
Chaturvedi K et al. Floating matrix dosage form for propranolol hydrochloride based on gas formation technique: development and in vitro evaluation. 2010 Oct-Dec Sci Pharm pmid:21179326
Terekhova EA et al. [Stearic acid methyl ether: a new extracellular metabolite of the obligate methylotrophic bacterium Methylophilus quaylei]. 2010 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:20391761
Kristó K et al. Effect of lubricant on spreading of coating liquid on surface of tablets containing pancreatin. 2010 Jul-Aug Pharm Dev Technol pmid:19772392
Badawy SI et al. Effect of spray-dried mannitol on the performance of microcrystalline cellulose-based wet granulated tablet formulation. 2010 Jul-Aug Pharm Dev Technol pmid:20088677
Kaur G et al. Chitosan-carboxymethyl tamarind kernel powder interpolymer complexation: investigations for colon drug delivery. 2010 Jan-Mar Sci Pharm pmid:21179370
Stanisz B et al. Influence of humidity and hydroxypropyl cellulose, hydroxypropylmethyl cellulose, glyceryl behenate or magnesium stearate on the degradation kinetics of quinapril hydrochloride in solid phase. 2010 Jan-Feb Acta Pol Pharm pmid:20210086
Aburahma MH et al. Preparation and in vitro/in vivo characterization of porous sublingual tablets containing ternary kneaded solid system of vinpocetine with î-cyclodextrin and hydroxy Acid. 2010 Apr-Jun Sci Pharm pmid:21179352
Singh B et al. Formulation optimization of hydrodynamically balanced oral controlled release bioadhesive tablets of tramadol hydrochloride. 2010 Apr-Jun Sci Pharm pmid:21179349
Legrand P and Rioux V The complex and important cellular and metabolic functions of saturated fatty acids. 2010 Lipids pmid:20625935
Hodson L et al. Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20628024
Hirabara SM et al. Saturated fatty acid-induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells. 2010 J. Cell. Physiol. pmid:19780047
Lehto T et al. Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy. 2010 J Control Release pmid:19744531
Tay T et al. Magnesium stearate increases salbutamol sulphate dispersion: what is the mechanism? 2010 Int J Pharm pmid:19748561
Elbaz A et al. Inhibition of fatty acid biosynthesis prevents adipocyte lipotoxicity on human osteoblasts in vitro. 2010 J. Cell. Mol. Med. pmid:19382912
Louis J et al. PAD4-dependent antibiosis contributes to the ssi2-conferred hyper-resistance to the green peach aphid. 2010 Mol. Plant Microbe Interact. pmid:20367470
Ospina-E JC et al. Development of combinations of chemically modified vegetable oils as pork backfat substitutes in sausages formulation. 2010 Meat Sci. pmid:20374815
Ye S et al. Polyunsaturated docosahexaenoic acid suppresses oxidative stress induced endothelial cell calcium influx by altering lipid composition in membrane caveolar rafts. 2010 Prostaglandins Leukot. Essent. Fatty Acids pmid:20206488
Rajab M et al. Optimization of a metformin effervescent floating tablet containing hydroxypropylmethylcellulose and stearic acid. 2010 Pharmazie pmid:20225651
Jeevanandham S et al. Sustain-release of various drugs from leucaena leucocephala polysaccharide. 2010 J Young Pharm pmid:21331185
Muro M et al. A conformation and orientation model of the carboxylic group of fatty acids dependent on chain length in a Langmuir monolayer film studied by polarization-modulation infrared reflection absorption spectroscopy. 2010 J Phys Chem B pmid:20718412
Mir VG et al. Application of crustacean chitin as a co-diluent in direct compression of tablets. 2010 AAPS PharmSciTech pmid:20238188
Chen JL et al. Metabolomics of gastric cancer metastasis detected by gas chromatography and mass spectrometry. 2010 World J. Gastroenterol. pmid:21155010
Teixeira AC et al. Phase behaviour of oleanolic acid, pure and mixed with stearic acid: Interactions and crystallinity. 2010 Chem. Phys. Lipids pmid:20599856
Kajiro H et al. Flexible two-dimensional square-grid coordination polymers: structures and functions. 2010 Int J Mol Sci pmid:21152303
Borah BM et al. Surface-modification-directed controlled adsorption of serum albumin onto magnetite nanocuboids synthesized in a gel-diffusion technique. 2010 J Colloid Interface Sci pmid:20621808
Coulon C et al. Chemical analysis of cellular and extracellular carbohydrates of a biofilm-forming strain Pseudomonas aeruginosa PA14. 2010 PLoS ONE pmid:21151973
Wieder DR and Pattimakiel L Examining the efficacy, safety, and patient acceptability of the combined contraceptive vaginal ring (NuvaRing). 2010 Int J Womens Health pmid:21151688
Kanjanavas P et al. Purification and characterization of organic solvent and detergent tolerant lipase from thermotolerant Bacillus sp. RN2. 2010 Int J Mol Sci pmid:21152301
Gentile CL et al. Fatty acids regulate CREBh via transcriptional mechanisms that are dependent on proteasome activity and insulin. 2010 Mol. Cell. Biochem. pmid:20607591
Bele MH et al. Effect of Flow Aids on Mucoadhesive Properties of Polymeric Discs of Polyoxyethylene and Carbopol 971P. 2010 Indian J Pharm Sci pmid:20582205
Li LO et al. Early hepatic insulin resistance in mice: a metabolomics analysis. 2010 Mol. Endocrinol. pmid:20150186
Tiemeyer S et al. Effect of surface charge distribution on the adsorption orientation of proteins to lipid monolayers. 2010 Langmuir pmid:20707324
Chen X et al. Plasma metabolomics reveals biomarkers of the atherosclerosis. 2010 J Sep Sci pmid:20730840
Horne I et al. Two conserved Z9-octadecanoic acid desaturases in the red flour beetle, Tribolium castaneum. 2010 Gene pmid:20709164
Vlachou M et al. Utilization of hydrophilic swellable polymers as carriers for sustained drug delivery from matrices and three layer tablet systems. 2010 Curr Drug Deliv pmid:20695845
Mas S et al. Local non-esterified fatty acids correlate with inflammation in atheroma plaques of patients with type 2 diabetes. 2010 Diabetes pmid:20200316
Walker S et al. Synthesis, processing and solid state excipient interactions of cucurbit[6]uril and its formulation into tablets for oral drug delivery. 2010 Mol. Pharm. pmid:20669974
Kurian GA et al. Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts. 2010 Chin Med pmid:20180993
Mathew M et al. Elevated plasma free fatty acids increase cardiovascular risk by inducing plasma biomarkers of endothelial activation, myeloperoxidase and PAI-1 in healthy subjects. 2010 Cardiovasc Diabetol pmid:20158910
Dong J et al. Cation-controlled crystal growth of silver stearate: cryo-TEM investigation of lithium vs sodium stearate. 2010 Langmuir pmid:20017506
Fu X et al. A rapid and universal bacteria-counting approach using CdSe/ZnS/SiO2 composite nanoparticles as fluorescence probe. 2010 Anal Bioanal Chem pmid:20016878
Zhang LJ et al. Hot-injection synthesis of highly luminescent and monodisperse CdS nanocrystals using thioacetamide and cadmium source with proper reactivity. 2010 J Colloid Interface Sci pmid:19932894
Balani PN et al. Influence of excipients in comilling on mitigating milling-induced amorphization or structural disorder of crystalline pharmaceutical actives. 2010 J Pharm Sci pmid:19902526
Li YW et al. [Studies on the chemical constituents of Ficus microcarpa]. 2010 Zhong Yao Cai pmid:21049616
Zhang L et al. Fabrication of nanotubules and microspheres from the self-assembly of amphiphilic monochain stearic acid derivatives. 2010 Langmuir pmid:21049915
Zarbakhsh A et al. Stabilization of alkylated azacrown ether by fatty acid at the air-water interface. 2010 Langmuir pmid:21049946
Alloatti A et al. Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. 2010 PLoS ONE pmid:21151902