stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Boutonneuse Fever D001907 5 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Syphilis, Latent D013592 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Chancroid D002602 4 associated lipids
Relapsing Fever D012061 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Anderson EK et al. Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis. 2012 Arterioscler. Thromb. Vasc. Biol. pmid:22556332
Becker S et al. Optimization of hepatocarcinoma uptake with radiolabeled lipiodol: development of new lipiodol formulations with increased viscosity. 2012 Cancer Biother. Radiopharm. pmid:22149684
Watanabe Y et al. The radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation. 2012 Diabetes pmid:22396206
Yavuz B et al. An overview on dry eye treatment: approaches for cyclosporin a delivery. 2012 ScientificWorldJournal pmid:22619624
Bonaduce I et al. New insights into the ageing of linseed oil paint binder: a qualitative and quantitative analytical study. 2012 PLoS ONE pmid:23166642
Itoh Y and Hasegawa T Polarization dependence of Raman scattering from a thin film involving optical anisotropy theorized for molecular orientation analysis. 2012 J Phys Chem A pmid:22551093
Brown PN et al. Determination of major phenolic compounds in Echinacea spp. raw materials and finished products by high-performance liquid chromatography with ultraviolet detection: single-laboratory validation matrix extension. 2011 Sep-Oct J AOAC Int pmid:22165004
Tomuta I et al. High-Throughput NIR-Chemometric Method for Meloxicam Assay from Powder Blends for Tableting. 2011 Oct-Dec Sci Pharm pmid:22145112
Nanjwade BK et al. Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs. 2011 Oct-Dec Sci Pharm pmid:22145101
Jelvehgari M et al. Formulation, characterization and in vitro evaluation of theophylline-loaded Eudragit RS 100 microspheres prepared by an emulsion-solvent diffusion/evaporation technique. 2011 Nov-Dec Pharm Dev Technol pmid:20722498
Qu WX et al. Analysis of fatty acids in A. szechenyianum Gay. by microwave-assisted extraction and gas chromatography-mass spectrometry. 2011 May-Jun Phytochem Anal pmid:20848395
Nath B et al. Preparation and in vitro dissolution profile of zidovudine loaded microspheres made of Eudragit RS 100, RL 100 and their combinations. 2011 May-Jun Acta Pol Pharm pmid:21648196
BozdaÄŸ-Pehlivan S et al. Evaluation of drug-excipient interaction in the formulation of celecoxib tablets. 2011 May-Jun Acta Pol Pharm pmid:21648198
Malik K et al. Taste masked microspheres of ofloxacin: formulation and evaluation of orodispersible tablets. 2011 Jul-Sep Sci Pharm pmid:21886910
Zaid AN et al. Formulation and bioequivalence of two valsartan tablets after a single oral administration. 2011 Jan-Mar Sci Pharm pmid:21617777
Shah DA et al. Stability indicating LC-method for estimation of paracetamol and lornoxicam in combined dosage form. 2011 Jan-Mar Sci Pharm pmid:21617776
Sasaki T and Tanaka S Adsorption behavior of some aromatic compounds on hydrophobic magnetite for magnetic separation. 2011 J. Hazard. Mater. pmid:21962863
Mottram AR et al. Fatty acids antagonize bupivacaine-induced I(Na) blockade. 2011 Clin Toxicol (Phila) pmid:21970771
Balducci AG et al. Layered lipid microcapsules for mesalazine delayed-release in children. 2011 Int J Pharm pmid:22001795
Jeon JH et al. Novel lipolytic enzymes identified from metagenomic library of deep-sea sediment. 2011 Evid Based Complement Alternat Med pmid:21845199
Jing F et al. Phylogenetic and experimental characterization of an acyl-ACP thioesterase family reveals significant diversity in enzymatic specificity and activity. 2011 BMC Biochem. pmid:21831316
Fini A et al. Diclofenac salts, part 6: release from lipid microspheres. 2011 J Pharm Sci pmid:21523784
Dani KG et al. Structural and functional analyses of a saturated acyl ACP thioesterase, type B from immature seed tissue of Jatropha curcas. 2011 Plant Biol (Stuttg) pmid:21489096
Huang HY et al. Co-delivery of anti-vascular endothelial growth factor siRNA and doxorubicin by multifunctional polymeric micelle for tumor growth suppression. 2011 J Biomed Mater Res A pmid:21465641
Hisazumi J et al. Quantification of pharmaceutical polymorphs and prediction of dissolution rate using theophylline tablet by terahertz spectroscopy. 2011 Chem. Pharm. Bull. pmid:21467671
Veit M and Thaa B Association of influenza virus proteins with membrane rafts. 2011 Adv Virol pmid:22312341
Wadher KJ et al. Formulation and evaluation of a sustained-release tablets of metformin hydrochloride using hydrophilic synthetic and hydrophobic natural polymers. 2011 Indian J Pharm Sci pmid:22303065
Guan Q et al. Preparation and pharmacokinetics of solid lipid nanoparticles loaded with pueraria flavones. 2011 J Control Release pmid:22195890
Wang K et al. Oxaliplatin-incorporated micelles eliminate both cancer stem-like and bulk cell populations in colorectal cancer. 2011 Int J Nanomedicine pmid:22238509
Hu C et al. Simultaneous utilization of glucose and xylose for lipid production by Trichosporon cutaneum. 2011 Biotechnol Biofuels pmid:21864398
Feng H et al. Pharmacokinetics study of bio-adhesive tablet of Panax notoginseng saponins. 2011 Int Arch Med pmid:21658246
Elokely KM et al. Fluorescence Spectrometric Determination of Drugs Containing α-Methylene Sulfone/Sulfonamide Functional Groups Using N-Methylnicotinamide Chloride as a Fluorogenic Agent. 2011 Int J Anal Chem pmid:21647288
Ip K et al. Analysis of complex metabolic behavior through pathway decomposition. 2011 BMC Syst Biol pmid:21639889
Ion G et al. Effects of canola and corn oil mimetic on Jurkat cells. 2011 Lipids Health Dis pmid:21631947
Yang J et al. Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: implications on anti-glucagon therapies for diabetes. 2011 BMC Genomics pmid:21631939
Roberts LD et al. The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue. 2011 Genome Biol. pmid:21843327
Ordelheide AM et al. The myocyte expression of adiponectin receptors and PPARδ is highly coordinated and reflects lipid metabolism of the human donors. 2011 Exp Diabetes Res pmid:21331343
Gilani K et al. Development of respirable nanomicelle carriers for delivery of amphotericin B by jet nebulization. 2011 J Pharm Sci pmid:20602350
Liu D et al. Synthesis and characterization of upconverting NaYF4:Er3+, Yb3+ nanocrystals via thermal decomposition of stearate precursor. 2011 J Nanosci Nanotechnol pmid:22413291
Pniewski T et al. Low-dose oral immunization with lyophilized tissue of herbicide-resistant lettuce expressing hepatitis B surface antigen for prototype plant-derived vaccine tablet formulation. 2011 J. Appl. Genet. pmid:21107787
González-Mira E et al. Potential use of nanostructured lipid carriers for topical delivery of flurbiprofen. 2011 J Pharm Sci pmid:20575052
Gallardo LA et al. Effect of europium(II) stearate on the mechanical properties and the oxidation resistance of UHMWPE. 2011 J Mech Behav Biomed Mater pmid:21565729
Abdel-Mottaleb MM et al. Lipid nanocapsules for dermal application: a comparative study of lipid-based versus polymer-based nanocarriers. 2011 Eur J Pharm Biopharm pmid:21558002
Yoo JY et al. A randomized controlled trial of oral phosphate binders in the treatment of pseudoxanthoma elasticum. 2011 J. Am. Acad. Dermatol. pmid:21496949
Mužíková J and Eimerová I A study of the compaction process and the properties of tablets made of a new co-processed starch excipient. 2011 Drug Dev Ind Pharm pmid:21469946
Lipasek RA et al. Effects of anticaking agents and relative humidity on the physical and chemical stability of powdered vitamin C. 2011 J. Food Sci. pmid:22417544
Süntar I et al. Wound Healing Activity of Rubus sanctus Schreber (Rosaceae): Preclinical Study in Animal Models. 2011 Evid Based Complement Alternat Med pmid:19755505
Stingl JC et al. Protocol for minimizing the risk of metachronous adenomas of the colorectum with green tea extract (MIRACLE): a randomised controlled trial of green tea extract versus placebo for nutriprevention of metachronous colon adenomas in the elderly population. 2011 BMC Cancer pmid:21851602
Andaloussi SE et al. Application of PepFect peptides for the delivery of splice-correcting oligonucleotides. 2011 Methods Mol. Biol. pmid:21053143
Yu DG et al. Coaxial electrospinning with organic solvent for controlling the size of self-assembled nanoparticles. 2011 Chem. Commun. (Camb.) pmid:21107459