| MeSH term | MeSH ID | Detail |
|---|---|---|
| Boutonneuse Fever | D001907 | 5 associated lipids |
| Yaws | D015001 | 4 associated lipids |
| Syphilis, Congenital | D013590 | 3 associated lipids |
| Syphilis, Latent | D013592 | 4 associated lipids |
| Mycoplasmatales Infections | D009180 | 6 associated lipids |
| Eczema, Dyshidrotic | D011146 | 1 associated lipids |
| Chancroid | D002602 | 4 associated lipids |
| Relapsing Fever | D012061 | 3 associated lipids |
| Tenosynovitis | D013717 | 3 associated lipids |
| Salivary Duct Calculi | D012465 | 2 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wu MH et al. | A novel sodium N-fatty acyl amino acid surfactant using silkworm pupae as stock material. | 2014 | Sci Rep | pmid:24651079 |
| Arijaje EO et al. | Effects of chemical and enzymatic modifications on starch-stearic acid complex formation. | 2014 | J. Agric. Food Chem. | pmid:24641427 |
| Treffer D et al. | In-line implementation of an image-based particle size measurement tool to monitor hot-melt extruded pellets. | 2014 | Int J Pharm | pmid:24614578 |
| Liau CP et al. | Preparation and characterization of polyhydroxybutyrate/polycaprolactone nanocomposites. | 2014 | ScientificWorldJournal | pmid:24600329 |
| Haware RV et al. | Application of multivariate methods to evaluate the functionality of bovine- and vegetable-derived magnesium stearate. | 2014 | J Pharm Sci | pmid:24596131 |
| Woo JO et al. | Development of a controlled release of salicylic acid loaded stearic acid-oleic acid nanoparticles in cream for topical delivery. | 2014 | ScientificWorldJournal | pmid:24578624 |
| Yee JK et al. | High oleic/stearic fatty-acid desaturation index in cord plasma from infants of mothers with gestational diabetes. | 2014 | J Perinatol | pmid:24577432 |
| CSIPKE Z | [Advanced training in prescription filling]. | 1954 | Gyogyszeresz | pmid:24551927 |
| Guo H et al. | In vitro and in vivo study of Gal-OS self-assembled nanoparticles for liver-targeting delivery of doxorubicin. | 2014 | J Pharm Sci | pmid:24549734 |
| Horváth LI et al. | Exchange rates at the lipid-protein interface of myelin proteolipid protein studied by spin-label electron spin resonance. | 1988 | Biochemistry | pmid:2450570 |
| Khodadoust S et al. | Identification and determination of the fatty acid composition of Quercus brantii growing in southwestern Iran by GC-MS. | 2014 | Nat. Prod. Res. | pmid:24499169 |
| Mohanty B et al. | Development and characterization of itraconazole-loaded solid lipid nanoparticles for ocular delivery. | 2015 | Pharm Dev Technol | pmid:24490828 |
| Sassa T et al. | Lorenzo's oil inhibits ELOVL1 and lowers the level of sphingomyelin with a saturated very long-chain fatty acid. | 2014 | J. Lipid Res. | pmid:24489110 |
| Wang JL et al. | Preparation and characterization of novel lipid carriers containing microalgae oil for food applications. | 2014 | J. Food Sci. | pmid:24446860 |
| Kumar SS et al. | Synthesis and characterization of curcumin loaded polymer/lipid based nanoparticles and evaluation of their antitumor effects on MCF-7 cells. | 2014 | Biochim. Biophys. Acta | pmid:24440669 |
| Guadalupe Sánchez-González E et al. | The influence of polymorphism on the manufacturability and in vitro dissolution of sulindac-containing hard gelatin capsules. | 2015 | Pharm Dev Technol | pmid:24417644 |
| Wang J et al. | A soybean acyl carrier protein, GmACP, is important for root nodule symbiosis. | 2014 | Mol. Plant Microbe Interact. | pmid:24400939 |
| Sertoglu E et al. | Comparison of plasma and erythrocyte membrane fatty acid compositions in patients with end-stage renal disease and type 2 diabetes mellitus. | 2014 | Chem. Phys. Lipids | pmid:24384240 |
| MuzÃková J et al. | A study of micronized poloxamers as lubricants in direct compression of tablets. | 2013 Nov-Dec | Acta Pol Pharm | pmid:24383332 |
| Kushner J et al. | A quality-by-design study for an immediate-release tablet platform: examining the relative impact of active pharmaceutical ingredient properties, processing methods, and excipient variability on drug product quality attributes. | 2014 | J Pharm Sci | pmid:24375069 |
| Samanta AK et al. | Energy-based analysis of cone milling process for the comminution of roller compacted flakes. | 2014 | Int J Pharm | pmid:24374608 |
| Maretti E et al. | Inhaled Solid Lipid Microparticles to target alveolar macrophages for tuberculosis. | 2014 | Int J Pharm | pmid:24374224 |
| Doig M et al. | Structure and friction of stearic acid and oleic acid films adsorbed on iron oxide surfaces in squalane. | 2014 | Langmuir | pmid:24364665 |
| Van Hoeck V et al. | Interaction between differential gene expression profile and phenotype in bovine blastocysts originating from oocytes exposed to elevated non-esterified fatty acid concentrations. | 2015 | Reprod. Fertil. Dev. | pmid:24360349 |
| Rico JE et al. | Compared with stearic acid, palmitic acid increased the yield of milk fat and improved feed efficiency across production level of cows. | 2014 | J. Dairy Sci. | pmid:24342689 |
| Li P et al. | Effect of non-esterified fatty acids on fatty acid metabolism-related genes in calf hepatocytes cultured in vitro. | 2013 | Cell. Physiol. Biochem. | pmid:24335176 |
| Saerens L et al. | Validation of an in-line Raman spectroscopic method for continuous active pharmaceutical ingredient quantification during pharmaceutical hot-melt extrusion. | 2014 | Anal. Chim. Acta | pmid:24331054 |
| Petridis L et al. | Spatial arrangement of organic compounds on a model mineral surface: implications for soil organic matter stabilization. | 2014 | Environ. Sci. Technol. | pmid:24328330 |
| Meulenaar J et al. | Development of an extended-release formulation of capecitabine making use of in vitro-in vivo correlation modelling. | 2014 | J Pharm Sci | pmid:24311366 |
| Mandal S et al. | Enhancement of survival of alginate-encapsulated Lactobacillus casei NCDC 298. | 2014 | J. Sci. Food Agric. | pmid:24307185 |
| Tsuchiya A et al. | Stearic acid serves as a potent inhibitor of protein tyrosine phosphatase 1B. | 2013 | Cell. Physiol. Biochem. | pmid:24296476 |
| Gouk SW et al. | Stearic acids at sn-1, 3 positions of TAG are more efficient at limiting fat deposition than palmitic and oleic acids in C57BL/6 mice. | 2014 | Br. J. Nutr. | pmid:24286356 |
| Nandini PT et al. | Formulation and evaluation of gemcitabine-loaded solid lipid nanoparticles. | 2015 | Drug Deliv | pmid:24283392 |
| Bertrand G et al. | [The value of polyglactin 910 combined with a resorbable bone wax for filling periodontal bone defects]. | 1985 | Actual Odontostomatol (Paris) | pmid:2425560 |
| Huang FC et al. | Expression and characterization of CYP52 genes involved in the biosynthesis of sophorolipid and alkane metabolism from Starmerella bombicola. | 2014 | Appl. Environ. Microbiol. | pmid:24242247 |
| Pan S et al. | Particle formation by supercritical fluid extraction and expansion process. | 2013 | ScientificWorldJournal | pmid:24223031 |
| Liu J et al. | Saturated fatty acids up-regulate COX-2 expression in prostate epithelial cells via toll-like receptor 4/NF-κB signaling. | 2014 | Inflammation | pmid:24221358 |
| Yuan B et al. | Laboratory-scale column study for remediation of TCE-contaminated aquifers using three-section controlled-release potassium permanganate barriers. | 2013 | J Environ Sci (China) | pmid:24218827 |
| Eiras CE et al. | Glycerine levels in the diets of crossbred bulls finished in feedlot: carcass characteristics and meat quality. | 2014 | Meat Sci. | pmid:24211551 |
| Jaumot J et al. | Blending process modeling and control by multivariate curve resolution. | 2013 | Talanta | pmid:24209372 |
| Uchimoto T et al. | Determination of useful ranges of mixing conditions for glycerin Fatty Acid ester by multiple regression analysis. | 2013 | Chem. Pharm. Bull. | pmid:24189302 |
| Michailidou VN et al. | Anisotropic diffusion of concentrated hard-sphere colloids near a hard wall studied by evanescent wave dynamic light scattering. | 2013 | J Chem Phys | pmid:24182077 |
| Wadström T et al. | Hydrophobized wound dressing in the treatment of experimental Staphylococcus aureus infections in the young pig. | 1985 | Acta Pathol Microbiol Immunol Scand B | pmid:2417448 |
| Seng PN and Debuch H | [Studies on the stearic acid dehydrogenase in the liver and brain of rats of various ages (author's transl)]. | 1975 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:241688 |
| Boshtam M et al. | Serum paraoxonase 1 activity is associated with fatty acid composition of high density lipoprotein. | 2013 | Dis. Markers | pmid:24167374 |
| Eltayeb M et al. | Electrosprayed core-shell polymer-lipid nanoparticles for active component delivery. | 2013 | Nanotechnology | pmid:24164775 |
| Dou J et al. | Preparation and evaluation in vitro and in vivo of docetaxel loaded mixed micelles for oral administration. | 2014 | Colloids Surf B Biointerfaces | pmid:24157590 |
| Bieri VG and Wallach DF | Variations of lipid-protein interactions in erythrocyte ghosts as a function of temperature and pH in physiological and non-physiological ranges. A study using a paramagnetic quenching of protein fluorescence by nitroxide lipid analogues. | 1975 | Biochim. Biophys. Acta | pmid:241415 |
| Guo H et al. | Self-assembled nanoparticles based on galactosylated O-carboxymethyl chitosan-graft-stearic acid conjugates for delivery of doxorubicin. | 2013 | Int J Pharm | pmid:24140544 |
| Chen JJ et al. | New pterosin sesquiterpenes and antitubercular constituents from Pteris ensiformis. | 2013 | Chem. Biodivers. | pmid:24130033 |
| Hagen RM et al. | Conjugated linoleate reduces prostate cancer viability whereas the effects of oleate and stearate are cell line-dependent. | 2013 | Anticancer Res. | pmid:24123008 |
| Kalm O et al. | Erythromycin stearate in acute maxillary sinusitis. | 1975 | Scand. J. Infect. Dis. | pmid:241119 |
| López-Cervantes J et al. | Effect of solvents and methods of stirring in extraction of lycopene, oleoresin and fatty acids from over-ripe tomato. | 2014 | Int J Food Sci Nutr | pmid:24111501 |
| Shibata E et al. | Free fatty acids inhibit protein tyrosine phosphatase 1B and activate Akt. | 2013 | Cell. Physiol. Biochem. | pmid:24107614 |
| Zhang W et al. | Stearylated antimicrobial peptide melittin and its retro isomer for efficient gene transfection. | 2013 | Bioconjug. Chem. | pmid:24107137 |
| Aznar-Moreno JA et al. | Sunflower (Helianthus annuus) long-chain acyl-coenzyme A synthetases expressed at high levels in developing seeds. | 2014 | Physiol Plant | pmid:24102504 |
| Chen Q et al. | Preparation and characterization of glycyrrhetinic acid-modified stearic acid-grafted chitosan micelles. | 2015 | Artif Cells Nanomed Biotechnol | pmid:24093764 |
| Jin Q et al. | A novel cationic microbubble coated with stearic acid-modified polyethylenimine to enhance DNA loading and gene delivery by ultrasound. | 2013 | PLoS ONE | pmid:24086748 |
| Cvetković Z et al. | Distribution of plasma fatty acids is associated with response to chemotherapy in non-Hodgkin's lymphoma patients. | 2013 | Med. Oncol. | pmid:24085546 |
| Mérian J et al. | Synthetic lipid nanoparticles targeting steroid organs. | 2013 | J. Nucl. Med. | pmid:24071507 |
| Šašiċ S et al. | Raman chemical mapping of magnesium stearate delivered by a punch-face lubrication system on the surface of placebo and active tablets. | 2013 | Appl Spectrosc | pmid:24067639 |
| Camacho-Chab JC et al. | Emulsifying activity and stability of a non-toxic bioemulsifier synthesized by Microbacterium sp. MC3B-10. | 2013 | Int J Mol Sci | pmid:24065097 |
| Neupane YR et al. | Lipid drug conjugate nanoparticle as a novel lipid nanocarrier for the oral delivery of decitabine: ex vivo gut permeation studies. | 2013 | Nanotechnology | pmid:24061410 |
| Franc A et al. | [Content uniformity of warfarin-containing mixtures and tablets]. | 2013 | Ceska Slov Farm | pmid:24047147 |
| Liu Z et al. | Changes in the electron paramagnetic resonance spectra of albumin-associated spin-labeled stearic acid as a diagnostic parameter of colorectal cancer. | 2013 | World J Surg Oncol | pmid:24025321 |
| Barber E et al. | Comparative actions of omega-3 fatty acids on in-vitro lipid droplet formation. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24012207 |
| Vadakkan MV et al. | Dry powder cationic lipopolymeric nanomicelle inhalation for targeted delivery of antitubercular drug to alveolar macrophage. | 2013 | Int J Nanomedicine | pmid:23990716 |
| Schrank S et al. | Microstructure of calcium stearate matrix pellets: a function of the drying process. | 2013 | J Pharm Sci | pmid:23983150 |
| Yang C et al. | Production of aviation fuel via catalytic hydrothermal decarboxylation of fatty acids in microalgae oil. | 2013 | Bioresour. Technol. | pmid:23973977 |
| MužÃková J and Sináglová P | A study of a new co-processed dry binder based on spray-dried lactose and microcrystalline cellulose. | 2013 | Ceska Slov Farm | pmid:23961814 |
| Maghsoodi M | Floating-pulsatile release multiparticulate system for chronopharmacotherapy: effect of some hydrophobic additives on the buoyancy and release behavior of particles. | 2014 | Drug Res (Stuttg) | pmid:23950100 |
| Choulis NH and Papadopoulos H | Factors effecting drug release from inert matrices. Part 1: effects of surfactants on the release of quinine sulfate. | 1975 | Pharmazie | pmid:239411 |
| Hussain T et al. | Effect of two hydrophobic polymers on the release of gliclazide from their matrix tablets. | 2013 Jul-Aug | Acta Pol Pharm | pmid:23923399 |
| Lorenzo JM | Changes on physico-chemical, textural, lipolysis and volatile compounds during the manufacture of dry-cured foal "cecina". | 2014 | Meat Sci. | pmid:23916960 |
| Wahl PR et al. | Inline monitoring and a PAT strategy for pharmaceutical hot melt extrusion. | 2013 | Int J Pharm | pmid:23911343 |
| Osorio JG and Muzzio FJ | Effects of powder flow properties on capsule filling weight uniformity. | 2013 | Drug Dev Ind Pharm | pmid:23902366 |
| Cunha TA et al. | Effect of stearic acid on enalapril stability and dissolution from multiparticulate solid dosage forms. | 2013 | AAPS PharmSciTech | pmid:23897034 |
| Hosseini A et al. | Direct compression of cushion-layered ethyl cellulose-coated extended release pellets into rapidly disintegrating tablets without changes in the release profile. | 2013 | Int J Pharm | pmid:23892153 |
| Subbaramaiah K et al. | Dietary polyphenols suppress elevated levels of proinflammatory mediators and aromatase in the mammary gland of obese mice. | 2013 | Cancer Prev Res (Phila) | pmid:23880231 |
| Vitturi DA et al. | Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase. | 2013 | J. Biol. Chem. | pmid:23878198 |
| Mohamed IO | Lipase-catalyzed acidolysis of palm mid fraction oil with palmitic and stearic Fatty Acid mixture for production of cocoa butter equivalent. | 2013 | Appl. Biochem. Biotechnol. | pmid:23877586 |
| Wang N et al. | The mechanism of hydrogen sulfide adsorption on fine rubber particle media (FRPM). | 2013 | J. Hazard. Mater. | pmid:23876257 |
| Asumadu-Mensah A et al. | Solid lipid dispersions: potential delivery system for functional ingredients in foods. | 2013 | J. Food Sci. | pmid:23865449 |
| Podczeck F et al. | Investigations into the tensile failure of doubly-convex cylindrical tablets under diametral loading using finite element methodology. | 2013 | Int J Pharm | pmid:23834836 |
| Saeedi Vahdat A et al. | Ultrasonic approach for viscoelastic and microstructure characterization of granular pharmaceutical tablets. | 2013 | Int J Pharm | pmid:23820132 |
| Høstmark AT et al. | Increased serum triglycerides and reduced HDL cholesterol in male rats after intake of ammonium chloride for 3 weeks. | 2013 | Lipids Health Dis | pmid:23800210 |
| Qi B et al. | A Golgi and tonoplast localized S-acyl transferase is involved in cell expansion, cell division, vascular patterning and fertility in Arabidopsis. | 2013 | New Phytol. | pmid:23795888 |
| Song W et al. | Importance of size and distribution of Ni nanoparticles for the hydrodeoxygenation of microalgae oil. | 2013 | Chemistry | pmid:23794421 |
| Zamora-Rojas E et al. | Prediction of fatty acids content in pig adipose tissue by near infrared spectroscopy: at-line versus in-situ analysis. | 2013 | Meat Sci. | pmid:23793086 |
| McGee R and Spector AA | Fatty acid biosynthesis in Erlich cells. The mechanism of short term control by exogenous free fatty acids. | 1975 | J. Biol. Chem. | pmid:237919 |
| Silberstein T et al. | Saturated fatty acid composition of human milk in Israel: a comparison between Jewish and Bedouin women. | 2013 | Isr. Med. Assoc. J. | pmid:23781748 |
| Khan AA et al. | Design, synthesis and in vitro anticancer evaluation of a stearic acid-based ester conjugate. | 2013 | Anticancer Res. | pmid:23749903 |
| Mensink RP and Katan MB | Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects. | 1990 | N. Engl. J. Med. | pmid:2374566 |
| Newman MJ | Inhibition of carcinoma and melanoma cell growth by type 1 transforming growth factor beta is dependent on the presence of polyunsaturated fatty acids. | 1990 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2371287 |
| Li C et al. | Enhanced performance and interfacial investigation of mineral-based composite phase change materials for thermal energy storage. | 2013 | Sci Rep | pmid:23712069 |
| Zhou X et al. | The effect of saturated fatty acids on methanogenesis and cell viability of Methanobrevibacter ruminantium. | 2013 | Archaea | pmid:23710130 |
| Zhang RJ et al. | Self-organized lateral patterning of a rare earth complex and stearic acid in Langmuir films. | 2001 | Chemphyschem | pmid:23696530 |
| Yan J et al. | Effect of proteins with different isoelectric points on the gene transfection efficiency mediated by stearic acid grafted chitosan oligosaccharide micelles. | 2013 | Mol. Pharm. | pmid:23679858 |
| Dangarembizi R et al. | Aloe ferox seed: a potential source of oil for cosmetic and pharmaceutical use. | 2013 | Nat Prod Commun | pmid:23678824 |
| Emken E | Human studies using isotope labeled fatty acids: answered and unanswered questions. | 2013 | J Oleo Sci | pmid:23648399 |