stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Boutonneuse Fever D001907 5 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Syphilis, Latent D013592 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Chancroid D002602 4 associated lipids
Relapsing Fever D012061 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Zhang X et al. Effect of Chemicals on Morphology and Luminescence of CdSe Quantum Dots. 2015 J Nanosci Nanotechnol pmid:26353513
Bhattacharya S et al. Increasing the stearate content in seed oil of Brassica juncea by heterologous expression of MlFatB affects lipid content and germination frequency of transgenic seeds. 2015 Plant Physiol. Biochem. pmid:26351151
Seethamraju S et al. Reactive interlayer based ultra-low moisture permeable membranes for organic photovoltaic encapsulation. 2015 Phys Chem Chem Phys pmid:26278515
Yang W et al. Facile Synthesis of Gd-Cu-In-S/ZnS Bimodal Quantum Dots with Optimized Properties for Tumor Targeted Fluorescence/MR In Vivo Imaging. 2015 ACS Appl Mater Interfaces pmid:26257133
Zhong T et al. Effects of ultrasound treatment on lipid self-association and properties of methylcellulose/stearic acid blending films. 2015 Carbohydr Polym pmid:26256202
He H et al. VB12-coated Gel-Core-SLN containing insulin: Another way to improve oral absorption. 2015 Int J Pharm pmid:26253378
Xu W et al. Bilayers at High pH in the Fatty Acid Soap Systems and the Applications for the Formation of Foams and Emulsions. 2015 J Phys Chem B pmid:26237503
Hoffmann M et al. Investigation into process-induced de-aggregation of cohesive micronised API particles. 2015 Int J Pharm pmid:26235919
Gong X et al. Dependence of tablet brittleness on tensile strength and porosity. 2015 Int J Pharm pmid:26226338
Liu G et al. Cell membrane-inspired polymeric micelles as carriers for drug delivery. 2015 Biomater Sci pmid:26222292
Qu L et al. Influence of coating material on the flowability and dissolution of dry-coated fine ibuprofen powders. 2015 Eur J Pharm Sci pmid:26215464
Kerth CR et al. Consumer sensory evaluation, fatty acid composition, and shelf-life of ground beef with subcutaneous fat trimmings from different carcass locations. 2015 Meat Sci. pmid:25688688
Tai Z et al. Biodegradable stearylated peptide with internal disulfide bonds for efficient delivery of siRNA in vitro and in vivo. 2015 Biomacromolecules pmid:25686200
Thakkar A et al. Evaluation of ibuprofen loaded solid lipid nanoparticles and its combination regimens for pancreatic cancer chemoprevention. 2015 Int. J. Oncol. pmid:25652350
Sagiri SS et al. Stearic acid based oleogels: a study on the molecular, thermal and mechanical properties. 2015 Mater Sci Eng C Mater Biol Appl pmid:25579972
Rana S et al. A spatio-temporal cardiomyocyte targeted vector system for efficient delivery of therapeutic payloads to regress cardiac hypertrophy abating bystander effect. 2015 J Control Release pmid:25575863
Wei X et al. Structure and properties of moisture-resistant konjac glucomannan films coated with shellac/stearic acid coating. 2015 Carbohydr Polym pmid:25542116
Zeng Q et al. Cationic micelle delivery of Trp2 peptide for efficient lymphatic draining and enhanced cytotoxic T-lymphocyte responses. 2015 J Control Release pmid:25540903
Piantoni P et al. Milk production responses to dietary stearic acid vary by production level in dairy cattle. 2015 J. Dairy Sci. pmid:25529423
Vercruysse J et al. Use of a continuous twin screw granulation and drying system during formulation development and process optimization. 2015 Eur J Pharm Biopharm pmid:25528462
Schrank S et al. The effect of the drying temperature on the properties of wet-extruded calcium stearate pellets: pellet microstructure, drug distribution, solid state and drug dissolution. 2015 Int J Pharm pmid:25526671
Cantor SL et al. Development and optimization of taste-masked orally disintegrating tablets (ODTs) of clindamycin hydrochloride. 2015 Drug Dev Ind Pharm pmid:25000481
Harding SV et al. Desaturation index versus isotopically measured de novo lipogenesis as an indicator of acute systemic lipogenesis. 2015 BMC Res Notes pmid:25879456
Silva-Neta IC et al. Expression of genes related to tolerance to low temperature for maize seed germination. 2015 Genet. Mol. Res. pmid:25867416
Jung SW et al. Mechanism of antibacterial activity of liposomal linolenic acid against Helicobacter pylori. 2015 PLoS ONE pmid:25793403
Othman AR et al. Elucidation of in-vitro anti-inflammatory bioactive compounds isolated from Jatropha curcas L. plant root. 2015 BMC Complement Altern Med pmid:25652309
Aardema H et al. Free fatty acid levels in fluid of dominant follicles at the preferred insemination time in dairy cows are not affected by early postpartum fatty acid stress. 2015 J. Dairy Sci. pmid:25648816
Ma W et al. Prospective association of fatty acids in the de novo lipogenesis pathway with risk of type 2 diabetes: the Cardiovascular Health Study. 2015 Am. J. Clin. Nutr. pmid:25527759
Li Y et al. Effects of sustained-release composite on the oxygen levels and sediment phosphorus fractions of an urban river in Shanghai. 2014 Sep-Oct Environ Technol pmid:25145170
Mu L et al. Erythrocyte saturated fatty acids and systemic inflammation in adults. 2014 Nov-Dec Nutrition pmid:25280420
Dubrovin EV et al. Statistical analysis of molecular nanotemplate driven DNA adsorption on graphite. 2014 Langmuir pmid:25470069
Wu JX et al. Chemical imaging and solid state analysis at compact surfaces using UV imaging. 2014 Int J Pharm pmid:25445531
Muselík J et al. Influence of process parameters on content uniformity of a low dose active pharmaceutical ingredient in a tablet formulation according to GMP. 2014 Acta Pharm pmid:25296681
Tsukada G et al. Temperature triggered shape memory effect of transpolyisoprene-based polymer. 2014 J Endod pmid:25260740
Pandey P et al. Excipient-process interactions and their impact on tablet compaction and film coating. 2014 J Pharm Sci pmid:25223603
Kushner J and Schlack H Commercial scale validation of a process scale-up model for lubricant blending of pharmaceutical powders. 2014 Int J Pharm pmid:25152166
Mateo-Ortiz D et al. Analysis of powder phenomena inside a Fette 3090 feed frame using in-line NIR spectroscopy. 2014 J Pharm Biomed Anal pmid:25128874
Horio T et al. Effect of particle shape on powder flowability of microcrystalline cellulose as determined using the vibration shear tube method. 2014 Int J Pharm pmid:25079435
Yodkhum K and Phaechamud T Hydrophobic chitosan sponges modified by aluminum monostearate and dehydrothermal treatment as sustained drug delivery system. 2014 Mater Sci Eng C Mater Biol Appl pmid:25063173
Han GR and Jang CH Detection of heavy-metal ions using liquid crystal droplet patterns modulated by interaction between negatively charged carboxylate and heavy-metal cations. 2014 Talanta pmid:25059128
Igne B et al. Modeling strategies for pharmaceutical blend monitoring and end-point determination by near-infrared spectroscopy. 2014 Int J Pharm pmid:25003830
Syamala US et al. Assessment of formulation factors on the release behaviour of BCS Class II drug from tablet dosage form using DoE. 2014 Curr Drug Deliv pmid:24975287
Liu J et al. Functional investigations on embryonic stem cells labeled with clinically translatable iron oxide nanoparticles. 2014 Nanoscale pmid:24969040
Tadros MI and Fahmy RH Controlled-release triple anti-inflammatory therapy based on novel gastroretentive sponges: characterization and magnetic resonance imaging in healthy volunteers. 2014 Int J Pharm pmid:24928130
Evoli S et al. Molecular simulations of β-lactoglobulin complexed with fatty acids reveal the structural basis of ligand affinity to internal and possible external binding sites. 2014 Proteins pmid:24916607
Loften JR et al. Invited review: palmitic and stearic acid metabolism in lactating dairy cows. 2014 J. Dairy Sci. pmid:24913651
Shah RM et al. Physicochemical characterization of solid lipid nanoparticles (SLNs) prepared by a novel microemulsion technique. 2014 J Colloid Interface Sci pmid:24910064
Ravi PR et al. A hybrid design to optimize preparation of lopinavir loaded solid lipid nanoparticles and comparative pharmacokinetic evaluation with marketed lopinavir/ritonavir coformulation. 2014 J. Pharm. Pharmacol. pmid:24697749
Miao L et al. Superparamagnetic-oil-filled nanocapsules of a ternary graft copolymer. 2014 Langmuir pmid:24684287
Treffer D et al. In-line implementation of an image-based particle size measurement tool to monitor hot-melt extruded pellets. 2014 Int J Pharm pmid:24614578
Haware RV et al. Application of multivariate methods to evaluate the functionality of bovine- and vegetable-derived magnesium stearate. 2014 J Pharm Sci pmid:24596131
Guo H et al. In vitro and in vivo study of Gal-OS self-assembled nanoparticles for liver-targeting delivery of doxorubicin. 2014 J Pharm Sci pmid:24549734
Rico JE et al. Compared with stearic acid, palmitic acid increased the yield of milk fat and improved feed efficiency across production level of cows. 2014 J. Dairy Sci. pmid:24342689
Petridis L et al. Spatial arrangement of organic compounds on a model mineral surface: implications for soil organic matter stabilization. 2014 Environ. Sci. Technol. pmid:24328330
Mandal S et al. Enhancement of survival of alginate-encapsulated Lactobacillus casei NCDC 298. 2014 J. Sci. Food Agric. pmid:24307185
Nehdi IA et al. Chamaerops humilis L. var. argentea André date palm seed oil: a potential dietetic plant product. 2014 J. Food Sci. pmid:24666023
Uğurlu T and Halaçoğlu MD Effects of some lubricants and evaluation of compression parameters on directly compressible powders. 2014 Pharm Dev Technol pmid:23590449
Pavićević ID et al. Fatty acids binding to human serum albumin: Changes of reactivity and glycation level of Cysteine-34 free thiol group with methylglyoxal. 2014 Chem. Biol. Interact. pmid:25451573
Lorenzo JM Changes on physico-chemical, textural, lipolysis and volatile compounds during the manufacture of dry-cured foal "cecina". 2014 Meat Sci. pmid:23916960
Maghsoodi M Floating-pulsatile release multiparticulate system for chronopharmacotherapy: effect of some hydrophobic additives on the buoyancy and release behavior of particles. 2014 Drug Res (Stuttg) pmid:23950100
Gouk SW et al. Stearic acids at sn-1, 3 positions of TAG are more efficient at limiting fat deposition than palmitic and oleic acids in C57BL/6 mice. 2014 Br. J. Nutr. pmid:24286356
Chen FY et al. TNYL peptide functional chitosan-g-stearate conjugate micelles for tumor specific targeting. 2014 Int J Nanomedicine pmid:25298734
Díaz R et al. Identification of fatty acids in canine seminal plasma. 2014 Andrologia pmid:23398451
Eiras CE et al. Glycerine levels in the diets of crossbred bulls finished in feedlot: carcass characteristics and meat quality. 2014 Meat Sci. pmid:24211551
Li N et al. Function of SREBP1 in the milk fat synthesis of dairy cow mammary epithelial cells. 2014 Int J Mol Sci pmid:25250914
Zhang SW et al. A method to evaluate the effect of contact with excipients on the surface crystallization of amorphous drugs. 2014 AAPS PharmSciTech pmid:25037732
Yao JJ et al. Efficient gene delivery system mediated by cis-aconitate-modified chitosan-g-stearic acid micelles. 2014 Int J Nanomedicine pmid:24971010
Fretts AM et al. Plasma phospholipid saturated fatty acids and incident atrial fibrillation: the Cardiovascular Health Study. 2014 J Am Heart Assoc pmid:24970268
Sonwai S and Ponprachanuvut P Studies of fatty acid composition, physicochemical and thermal properties, and crystallization behavior of mango kernel fats from various Thai varieties. 2014 J Oleo Sci pmid:24919475
Park H et al. Stacking of a stearoyl-ACP thioesterase with a dual-silenced palmitoyl-ACP thioesterase and ∆12 fatty acid desaturase in transgenic soybean. 2014 Plant Biotechnol. J. pmid:24909647
Gillman JD et al. Deletions of the SACPD-C locus elevate seed stearic acid levels but also result in fatty acid and morphological alterations in nitrogen fixing nodules. 2014 BMC Plant Biol. pmid:24886084
Carrero-Colón M et al. Mutations in SACPD-C result in a range of elevated stearic acid concentration in soybean seed. 2014 PLoS ONE pmid:24846334
Gebauer SK et al. Impact of stearic acid and oleic acid on hemostatic factors in the context of controlled diets consumed by healthy men. 2014 Eur J Clin Nutr pmid:24736679
Liau CP et al. Preparation and characterization of polyhydroxybutyrate/polycaprolactone nanocomposites. 2014 ScientificWorldJournal pmid:24600329
Woo JO et al. Development of a controlled release of salicylic acid loaded stearic acid-oleic acid nanoparticles in cream for topical delivery. 2014 ScientificWorldJournal pmid:24578624
Yee JK et al. High oleic/stearic fatty-acid desaturation index in cord plasma from infants of mothers with gestational diabetes. 2014 J Perinatol pmid:24577432
López-Cervantes J et al. Effect of solvents and methods of stirring in extraction of lycopene, oleoresin and fatty acids from over-ripe tomato. 2014 Int J Food Sci Nutr pmid:24111501
Banovec M et al. The effect of cores and coating dispersion composition on the mechanical and adhesion properties of hydroxypropyl methylcellulose films. 2014 Pharmazie pmid:25158570
Wang JL et al. Preparation and characterization of novel lipid carriers containing microalgae oil for food applications. 2014 J. Food Sci. pmid:24446860
Gao L et al. Cloning and functional expression of a cDNA encoding stearoyl-ACP Δ9-desaturase from the endosperm of coconut (Cocos nucifera L.). 2014 Gene pmid:25038276
Arijaje EO et al. Effects of chemical and enzymatic modifications on starch-stearic acid complex formation. 2014 J. Agric. Food Chem. pmid:24641427
Zhao X et al. Diet modulation is an effective complementary agent in preventing and treating breast cancer lung metastasis. 2014 Clin. Exp. Metastasis pmid:24832758
Aznar-Moreno JA et al. Sunflower (Helianthus annuus) long-chain acyl-coenzyme A synthetases expressed at high levels in developing seeds. 2014 Physiol Plant pmid:24102504
Huang FC et al. Expression and characterization of CYP52 genes involved in the biosynthesis of sophorolipid and alkane metabolism from Starmerella bombicola. 2014 Appl. Environ. Microbiol. pmid:24242247
Sassa T et al. Lorenzo's oil inhibits ELOVL1 and lowers the level of sphingomyelin with a saturated very long-chain fatty acid. 2014 J. Lipid Res. pmid:24489110
Maretti E et al. Inhaled Solid Lipid Microparticles to target alveolar macrophages for tuberculosis. 2014 Int J Pharm pmid:24374224
Samanta AK et al. Energy-based analysis of cone milling process for the comminution of roller compacted flakes. 2014 Int J Pharm pmid:24374608
Doig M et al. Structure and friction of stearic acid and oleic acid films adsorbed on iron oxide surfaces in squalane. 2014 Langmuir pmid:24364665
Sertoglu E et al. Comparison of plasma and erythrocyte membrane fatty acid compositions in patients with end-stage renal disease and type 2 diabetes mellitus. 2014 Chem. Phys. Lipids pmid:24384240
Khodadoust S et al. Identification and determination of the fatty acid composition of Quercus brantii growing in southwestern Iran by GC-MS. 2014 Nat. Prod. Res. pmid:24499169
Wu MH et al. A novel sodium N-fatty acyl amino acid surfactant using silkworm pupae as stock material. 2014 Sci Rep pmid:24651079
Kumar SS et al. Synthesis and characterization of curcumin loaded polymer/lipid based nanoparticles and evaluation of their antitumor effects on MCF-7 cells. 2014 Biochim. Biophys. Acta pmid:24440669
Wang J et al. A soybean acyl carrier protein, GmACP, is important for root nodule symbiosis. 2014 Mol. Plant Microbe Interact. pmid:24400939
Saerens L et al. Validation of an in-line Raman spectroscopic method for continuous active pharmaceutical ingredient quantification during pharmaceutical hot-melt extrusion. 2014 Anal. Chim. Acta pmid:24331054
Crowe FL et al. Circulating fatty acids and prostate cancer risk: individual participant meta-analysis of prospective studies. 2014 J. Natl. Cancer Inst. pmid:25210201
Rahman MH et al. Preparation, characterization and in vitro cytotoxicity assay of curcumin loaded solid lipid nanoparticle in IMR32 neuroblastoma cell line. 2014 Pak J Pharm Sci pmid:25176384
Liu J et al. Saturated fatty acids up-regulate COX-2 expression in prostate epithelial cells via toll-like receptor 4/NF-κB signaling. 2014 Inflammation pmid:24221358
Kushner J et al. A quality-by-design study for an immediate-release tablet platform: examining the relative impact of active pharmaceutical ingredient properties, processing methods, and excipient variability on drug product quality attributes. 2014 J Pharm Sci pmid:24375069
Dou J et al. Preparation and evaluation in vitro and in vivo of docetaxel loaded mixed micelles for oral administration. 2014 Colloids Surf B Biointerfaces pmid:24157590
Meulenaar J et al. Development of an extended-release formulation of capecitabine making use of in vitro-in vivo correlation modelling. 2014 J Pharm Sci pmid:24311366