stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Boutonneuse Fever D001907 5 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Syphilis, Latent D013592 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Chancroid D002602 4 associated lipids
Relapsing Fever D012061 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Sasaki T and Tanaka S Adsorption behavior of some aromatic compounds on hydrophobic magnetite for magnetic separation. 2011 J. Hazard. Mater. pmid:21962863
Mottram AR et al. Fatty acids antagonize bupivacaine-induced I(Na) blockade. 2011 Clin Toxicol (Phila) pmid:21970771
Balducci AG et al. Layered lipid microcapsules for mesalazine delayed-release in children. 2011 Int J Pharm pmid:22001795
Kumar RV and Sinha VR Tailoring of drug delivery of 5-fluorouracil to the colon via a mixed film coated unit system. 2011 Acta Pharm pmid:21945913
Severino P et al. Polymorphism, crystallinity and hydrophilic-lipophilic balance of stearic acid and stearic acid-capric/caprylic triglyceride matrices for production of stable nanoparticles. 2011 Colloids Surf B Biointerfaces pmid:21543196
Zhou QT et al. Investigation of the extent of surface coating via mechanofusion with varying additive levels and the influences on bulk powder flow properties. 2011 Int J Pharm pmid:21527321
Wang S et al. Insertion of an esterase gene into a specific locust pathogen (Metarhizium acridum) enables it to infect caterpillars. 2011 PLoS Pathog. pmid:21731492
Manzano E et al. Study of the GC-MS determination of the palmitic-stearic acid ratio for the characterisation of drying oil in painting: La Encarnación by Alonso Cano as a case study. 2011 Talanta pmid:21530791
Prabhakar N et al. Polyaniline Langmuir-Blodgett film based aptasensor for ochratoxin A detection. 2011 Biosens Bioelectron pmid:21514815
Fini A et al. Diclofenac salts, part 6: release from lipid microspheres. 2011 J Pharm Sci pmid:21523784
Dani KG et al. Structural and functional analyses of a saturated acyl ACP thioesterase, type B from immature seed tissue of Jatropha curcas. 2011 Plant Biol (Stuttg) pmid:21489096
Haghjou N et al. Sustained release intraocular drug delivery devices for treatment of uveitis. 2011 J Ophthalmic Vis Res pmid:22454753
Huang HY et al. Co-delivery of anti-vascular endothelial growth factor siRNA and doxorubicin by multifunctional polymeric micelle for tumor growth suppression. 2011 J Biomed Mater Res A pmid:21465641
Hisazumi J et al. Quantification of pharmaceutical polymorphs and prediction of dissolution rate using theophylline tablet by terahertz spectroscopy. 2011 Chem. Pharm. Bull. pmid:21467671
Guntupalli R et al. Phage Langmuir monolayers and Langmuir-Blodgett films. 2011 Colloids Surf B Biointerfaces pmid:20843668
Saeed M et al. Assessment of diffuse transmission and reflection modes in near-infrared quantification, part 2: DIFFuse reflection information depth. 2011 J Pharm Sci pmid:20862671
Uchino T et al. Effects of coating materials and size of titanium dioxide particles on their cytotoxicity and penetration into the cellular membrane. 2011 J Toxicol Sci pmid:21297346
Park MY et al. Hog millet (Panicum miliaceum L.)-supplemented diet ameliorates hyperlipidemia and hepatic lipid accumulation in C57BL/6J-ob/ob mice. 2011 Nutr Res Pract pmid:22259675
Basu B et al. Formulation and evaluation of fast dissolving tablets of cinnarizine using superdisintegrant blends and subliming material. 2011 J Adv Pharm Technol Res pmid:22247895
Guan Q et al. Preparation and pharmacokinetics of solid lipid nanoparticles loaded with pueraria flavones. 2011 J Control Release pmid:22195890
Zhang Y and Clapp A Overview of stabilizing ligands for biocompatible quantum dot nanocrystals. 2011 Sensors (Basel) pmid:22247651
Jishnu V et al. Formulation and evaluation of cephalexin extended release matrix tablets using 3 factorial design. 2011 J Young Pharm pmid:22224031
Wang K et al. Oxaliplatin-incorporated micelles eliminate both cancer stem-like and bulk cell populations in colorectal cancer. 2011 Int J Nanomedicine pmid:22238509
Du YZ et al. Receptor-mediated gene delivery by folic acid-modified stearic acid-grafted chitosan micelles. 2011 Int J Nanomedicine pmid:21845046
Oosterveer MH et al. Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function. 2011 Nutr Metab (Lond) pmid:22201701
Raynes Greenow CH et al. Antibiotics for ureaplasma in the vagina in pregnancy. 2011 Cochrane Database Syst Rev pmid:21901685
Steidl S et al. Mâ‚… muscarinic receptors mediate striatal dopamine activation by ventral tegmental morphine and pedunculopontine stimulation in mice. 2011 PLoS ONE pmid:22102904
Meissner M et al. Bile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rate. 2011 PLoS ONE pmid:22087215
Wu DJ et al. Metabonomics-based omics study and atherosclerosis. 2011 J Clin Bioinforma pmid:22040517
Guschina I et al. Lipid classes and fatty acid patterns are altered in the brain of γ-synuclein null mutant mice. 2011 Lipids pmid:20963507
Walash MI et al. Development and validation of stability indicating method for determination of sertraline following ICH guidlines and its determination in pharmaceuticals and biological fluids. 2011 Chem Cent J pmid:21996025
El-Enany NM et al. Spectrofluorimetric determination of sertraline in dosage forms and human plasma through derivatization with 9-fluorenylmethyl chloroformate. 2011 Chem Cent J pmid:21978386
Yin AW and Huang SJ [Research on chemical constituents of xuefu zhuyu decoction]. 2011 Zhong Yao Cai pmid:22372145
Tachibana H Green tea polyphenol sensing. 2011 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:21422740
Rajendraprasad N et al. Titrimetric and spectrophotometric assay of oxcarbazepine in pharmaceuticals using N-bromosuccinimide and bromopyrogallol red. 2011 Int J Anal Chem pmid:21785594
Bhope SG et al. Design and development of a stable polyherbal formulation based on the results of compatibility studies. 2011 Pharmacognosy Res pmid:21772756
Williams KJ et al. The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo. 2011 Tuberculosis (Edinb) pmid:21764638
Zhang H et al. Seed Oil of Brucea javanica Induces Apoptotic Death of Acute Myeloid Leukemia Cells via Both the Death Receptors and the Mitochondrial-Related Pathways. 2011 Evid Based Complement Alternat Med pmid:21760826
Raza A and Zia-Ul-Haq M Application of Certain π-Acceptors for the Spectrophotometric Determination of Alendronate Sodium in Pharmaceutical Bulk and Dosage Forms. 2011 Int J Anal Chem pmid:21760789
Abdulrahman SA and Basavaiah K Sensitive and selective spectrophotometric determination of gabapentin in capsules using two nitrophenols as chromogenic agents. 2011 Int J Anal Chem pmid:21760787
Zenita O and Basavaiah K Utility of N-bromosuccinimide for the titrimetric and spectrophotometric determination of famotidine in pharmaceutical formulations. 2011 Int J Anal Chem pmid:21760785
Almer G et al. Adiponectin-coated nanoparticles for enhanced imaging of atherosclerotic plaques. 2011 Int J Nanomedicine pmid:21753879
Brown JD et al. VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses. 2011 PLoS ONE pmid:21750705
Fernandez C et al. Altered desaturation and elongation of fatty acids in hormone-sensitive lipase null mice. 2011 PLoS ONE pmid:21738729
Singhal A et al. Colon-targeted quercetin delivery using natural polymer to enhance its bioavailability. 2011 Pharmacognosy Res pmid:21731393
Houmard JA et al. Is there a metabolic program in the skeletal muscle of obese individuals? 2011 J Obes pmid:21603262
Li C et al. Prevention of carcinogenesis and inhibition of breast cancer tumor burden by dietary stearate. 2011 Carcinogenesis pmid:21586513
Kalinina OV et al. Combinations of protein-chemical complex structures reveal new targets for established drugs. 2011 PLoS Comput. Biol. pmid:21573205
Amaya KR et al. Small molecule analysis and imaging of fatty acids in the zebra finch song system using time-of-flight-secondary ion mass spectrometry. 2011 J. Neurochem. pmid:21496023
Duangjit S et al. Characterization and In Vitro Skin Permeation of Meloxicam-Loaded Liposomes versus Transfersomes. 2011 J Drug Deliv pmid:21490750
Kumaravelrajan R et al. Development and evaluation of controlled porosity osmotic pump for nifedipine and metoprolol combination. 2011 Lipids Health Dis pmid:21477386
Kordyukova LV et al. Linker and/or transmembrane regions of influenza A/Group-1, A/Group-2, and type B virus hemagglutinins are packed differently within trimers. 2011 Biochim. Biophys. Acta pmid:21420932
Sahu SK et al. Hydrophobically modified carboxymethyl chitosan nanoparticles targeted delivery of paclitaxel. 2011 J Drug Target pmid:20367067
Liu Y et al. Graphene and graphene oxide: two ideal choices for the enrichment and ionization of long-chain fatty acids free from matrix-assisted laser desorption/ionization matrix interference. 2011 Rapid Commun. Mass Spectrom. pmid:22006384
Fabiano A et al. Metabolomic analysis of bronchoalveolar lavage fluid in preterm infants complicated by respiratory distress syndrome: preliminary results. 2011 J. Matern. Fetal. Neonatal. Med. pmid:21781003
Santos GM et al. Negative regulation by nuclear receptors: a plethora of mechanisms. 2011 Trends Endocrinol. Metab. pmid:21196123
Watanabe H et al. Biosynthetic Pathway for Sex Pheromone Components Produced in a Plusiinae Moth, Plusia festucae. 2011 Front Endocrinol (Lausanne) pmid:22649385
Yee JK et al. Organ-specific alterations in fatty acid de novo synthesis and desaturation in a rat model of programmed obesity. 2011 Lipids Health Dis pmid:21569358
Shivanand K et al. In vivo bioavailability studies of sumatriptan succinate buccal tablets. 2011 Daru pmid:22615661
Gande S and Rao Y Sustained-release effervescent floating matrix tablets of baclofen: development, optimization and in vitro-in vivo evaluation in healthy human volunteers. 2011 Daru pmid:22615658
Varshosaz J et al. Development of novel budesonide pellets based on CODES(TM) technology: In vitro/in vivo evaluation in induced colitis in rats. 2011 Daru pmid:22615647
Dey S et al. Formulation and optimization of sustained release Stavudine microspheres using response surface methodology. 2011 ISRN Pharm pmid:22389855
Prajapati ST et al. Formulation and evaluation of controlled-release tablet of zolpidem tartrate by melt granulation technique. 2011 ISRN Pharm pmid:22389845
Flowers MT et al. Metabolic changes in skin caused by Scd1 deficiency: a focus on retinol metabolism. 2011 PLoS ONE pmid:21573029
Kulinowski P et al. Magnetic resonance imaging and image analysis for assessment of HPMC matrix tablets structural evolution in USP Apparatus 4. 2011 Pharm. Res. pmid:21181545
Gilani K et al. Development of respirable nanomicelle carriers for delivery of amphotericin B by jet nebulization. 2011 J Pharm Sci pmid:20602350
Mantzaris MD et al. Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells. 2011 FEBS J. pmid:21182590
González-Mira E et al. Potential use of nanostructured lipid carriers for topical delivery of flurbiprofen. 2011 J Pharm Sci pmid:20575052
Dasu MR and Jialal I Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20959532
Kouskoumvekaki I and Panagiotou G Navigating the human metabolome for biomarker identification and design of pharmaceutical molecules. 2011 J. Biomed. Biotechnol. pmid:20936122
Kasliwal N et al. Formulation, development, and performance evaluation of metoclopramide HCl oro-dispersible sustained release tablet. 2011 Arch. Pharm. Res. pmid:22076769
Wang GG et al. Self-assembled biomimetic superhydrophobic CaCO3 coating inspired from fouling mineralization in geothermal water. 2011 Langmuir pmid:21919516
Basu BJ and Manasa J Effect of deposition parameters on the wettability and microstructure of superhydrophobic films with hierarchical micro-nano structures. 2011 J Colloid Interface Sci pmid:21864844
Asahi H et al. Plasmodium falciparum: differing effects of non-esterified fatty acids and phospholipids on intraerythrocytic growth in serum-free medium. 2011 Exp. Parasitol. pmid:21095186
Seow LJ et al. Anti-angiogenic activity of Gynura segetum leaf extracts and its fractions. 2011 J Ethnopharmacol pmid:21167271
Price ER et al. Carnitine palmitoyl transferase activity and whole muscle oxidation rates vary with fatty acid substrate in avian flight muscles. 2011 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. pmid:21153644
Lin Y et al. Nucleating effect of calcium stearate coated CaCO(3) nanoparticles on polypropylene. 2011 J Colloid Interface Sci pmid:21122873
MacDonald AM et al. A modified supported bilayer/diblock polymer--working towards a tunable coating for capillary electrophoresis. 2011 J Chromatogr A pmid:21122870
Liu X et al. Synthesis of high quality and stability CdS quantum dots with overlapped nucleation-growth process in large scale. 2011 J Colloid Interface Sci pmid:21040929
Tamilvanan S et al. In vitro and in vivo evaluation of hydrophilic and hydrophobic polymers-based nicorandil-loaded peroral tablet compared with its once-daily commercial sustained-release tablet. 2011 Drug Dev Ind Pharm pmid:20923389
Liu H et al. A surfactant-free recipe for shape-controlled synthesis of CdSe nanocrystals. 2011 Nanotechnology pmid:21169661
Aardema H et al. Oleic acid prevents detrimental effects of saturated fatty acids on bovine oocyte developmental competence. 2011 Biol. Reprod. pmid:21311036
Pingali K et al. Mixing order of glidant and lubricant--influence on powder and tablet properties. 2011 Int J Pharm pmid:21356286
Morinaga N et al. Synthesis of fatty acid sterol esters using cholesterol esterase from Trichoderma sp. AS59. 2011 Enzyme Microb. Technol. pmid:22113022
Gremos S et al. Direct enzymatic acylation of cellulose pretreated in BMIMCl ionic liquid. 2011 Bioresour. Technol. pmid:20888759
Cheng YY et al. A novel cold-adapted lipase from Sorangium cellulosum strain So0157-2: gene cloning, expression, and enzymatic characterization. 2011 Int J Mol Sci pmid:22072918
Peng Q et al. A novel esterase gene cloned from a metagenomic library from neritic sediments of the South China Sea. 2011 Microb. Cell Fact. pmid:22067554
Yu WL et al. Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. 2011 Microb. Cell Fact. pmid:22047615
Yuan H et al. Stearic acid-g-chitosan polymeric micelle for oral drug delivery: in vitro transport and in vivo absorption. 2011 Mol. Pharm. pmid:21138243
Krogmann A et al. Inflammatory response of human coronary artery endothelial cells to saturated long-chain fatty acids. 2011 Microvasc. Res. pmid:21112343
Andaloussi SE et al. Application of PepFect peptides for the delivery of splice-correcting oligonucleotides. 2011 Methods Mol. Biol. pmid:21053143
Yu DG et al. Coaxial electrospinning with organic solvent for controlling the size of self-assembled nanoparticles. 2011 Chem. Commun. (Camb.) pmid:21107459
Das SC et al. Use of surface energy distributions by inverse gas chromatography to understand mechanofusion processing and functionality of lactose coated with magnesium stearate. 2011 Eur J Pharm Sci pmid:21621612
Laverroux S et al. Isomerization of vaccenic acid to cis and trans C18:1 isomers during biohydrogenation by rumen microbes. 2011 Lipids pmid:21706384
Someshwar K et al. Formulation and evaluation of effervescent floating tablets of tizanidine hydrochloride. 2011 Acta Pharm pmid:21684848
Sekharan TR et al. Formulation and Evaluation of Hydroxypropyl Methylcellulose-based Controlled Release Matrix Tablets for Theophylline. 2011 Indian J Pharm Sci pmid:22707833
Pani NR et al. Compatibility studies of nateglinide with excipients in immediate release tablets. 2011 Acta Pharm pmid:21684850
Nagarsekar KS et al. Antioxidant and antilipid peroxidation potential of supercritical fluid extract and ethanol extract of leaves of vitex negundo linn. 2011 Indian J Pharm Sci pmid:22707827
Masareddy R et al. Development of Orodispersible Tizanidine HCl Tablets Using Spray Dried Coprocessed Exipient Bases. 2011 Indian J Pharm Sci pmid:22707822
Lan DM et al. A novel cold-active lipase from Candida albicans: cloning, expression and characterization of the recombinant enzyme. 2011 Int J Mol Sci pmid:21747717