| MeSH term | MeSH ID | Detail |
|---|---|---|
| Boutonneuse Fever | D001907 | 5 associated lipids |
| Yaws | D015001 | 4 associated lipids |
| Syphilis, Congenital | D013590 | 3 associated lipids |
| Syphilis, Latent | D013592 | 4 associated lipids |
| Mycoplasmatales Infections | D009180 | 6 associated lipids |
| Eczema, Dyshidrotic | D011146 | 1 associated lipids |
| Chancroid | D002602 | 4 associated lipids |
| Relapsing Fever | D012061 | 3 associated lipids |
| Tenosynovitis | D013717 | 3 associated lipids |
| Salivary Duct Calculi | D012465 | 2 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Colmano G et al. | Activated silver coatings for surgical implants. | 1979 | Va Med | pmid:316624 |
| Butzler JP et al. | Clinical and pharmacological evaluation of different preparations of oral erythromycin. | 1979 | Chemotherapy | pmid:316377 |
| Udod VM et al. | [Microbial breakdown of stearox-6 and a study of the genetic determination of the nature of the degradative activity]. | 1987 May-Jun | Mikrobiol. Zh. | pmid:3150493 |
| Takenaka T et al. | Effects of arachidonic acid and the other long-chain fatty acids on the membrane currents in the squid giant axon. | 1988 | J. Membr. Biol. | pmid:3147335 |
| Abbott AA et al. | A prospective randomized trial on efficacy of antibiotic prophylaxis in asymptomatic teeth with pulpal necrosis and associated periapical pathosis. | 1988 | Oral Surg. Oral Med. Oral Pathol. | pmid:3144686 |
| Kraus G et al. | [The modification of different element levels in human blood by occupational cadmium exposure]. | 1988 | Zentralbl Bakteriol Mikrobiol Hyg B | pmid:3138836 |
| Aho P and Männistö PT | Effects of two erythromycins, doxycycline and phenoxymethylpenicillin on human leucocyte chemotaxis in vitro. | 1988 | J. Antimicrob. Chemother. | pmid:3134323 |
| Kaya K and Kusumi T | Isolation and structural characterization of a diacyltaurolipid in cells of Tetrahymena mimbres. | 1988 | Biochim. Biophys. Acta | pmid:3132980 |
| Chu SH and Walker WA | Development of the gastrointestinal mucosal barrier: changes in phospholipid head groups and fatty acid composition of intestinal microvillus membranes from newborn and adult rats. | 1988 | Pediatr. Res. | pmid:3131728 |
| Schmid KM and Patterson GW | Effects of cyclopropenoid fatty acids on fungal growth and lipid composition. | 1988 | Lipids | pmid:3131612 |
| Dudley DT et al. | Depletion of arachidonic acid from GH3 cells. Effects on inositol phospholipid turnover and cellular activation. | 1987 | Biochem. J. | pmid:3120699 |
| Shanson DC | Antibiotic prophylaxis of infective endocarditis in the United Kingdom and Europe. | 1987 | J. Antimicrob. Chemother. | pmid:3119557 |
| Taylor AJ et al. | An alternative explanation for the changes in erythrocyte fatty acids observed in diabetes mellitus. | 1987 | Clin. Chem. | pmid:3119255 |
| Hohl C and Rösen P | Arachidonic acid metabolism in isolated rat heart myocytes. | 1987 | Prog. Clin. Biol. Res. | pmid:3118380 |
| Halát G et al. | Effects of incomplete ischemia and subsequent recirculation on free palmitate, stearate, oleate and arachidonate levels in lumbar and cervical spinal cord of rabbit. | 1987 | Gen. Physiol. Biophys. | pmid:3117617 |
| Crost S et al. | Hormonal effects on mitochondrial respiration: potential role of endogenous lipolytic activities. | 1987 | Arch. Biochem. Biophys. | pmid:3113334 |
| Morse DR et al. | Infectious flare-ups and serious sequelae following endodontic treatment: a prospective randomized trial on efficacy of antibiotic prophylaxis in cases of asymptomatic pulpal-periapical lesions. | 1987 | Oral Surg. Oral Med. Oral Pathol. | pmid:3112672 |
| DeGeorge JJ et al. | Acetylcholine stimulates selective liberation and re-esterification of arachidonate and accumulation of inositol phosphates and glycerophosphoinositol in C62B glioma cells. | 1987 | J. Biol. Chem. | pmid:3110145 |
| Swendsen CL et al. | Human neutrophils incorporate arachidonic acid and saturated fatty acids into separate molecular species of phospholipids. | 1987 | Biochim. Biophys. Acta | pmid:3105590 |
| Søreide O et al. | Inadequacy of oleic acid in erythrocytes as a marker of malignancies. | 1987 | Br Med J (Clin Res Ed) | pmid:3103770 |
| Dudley DT and Spector AA | Inositol phospholipid arachidonic acid metabolism in GH3 pituitary cells. | 1986 | Biochem. J. | pmid:3098231 |
| Reddy TS et al. | Fatty acid composition and arachidonic acid metabolism in vitreous lipids from canine and human eyes. | 1986 | Curr. Eye Res. | pmid:3089690 |
| Villa P et al. | Effects of a new fluorinated macrolide (P-0501A) and other erythromycins on drug metabolizing enzymes in rat liver. | 1986 | J. Antibiot. | pmid:3084433 |
| Smith DM and Waite M | Phospholipid metabolism in human neutrophil subfractions. | 1986 | Arch. Biochem. Biophys. | pmid:3083776 |
| Ginóbili de MartÃnez MS et al. | Asymmetry of diacylglycerol metabolism in rat cerebral hemispheres. | 1986 | J. Neurochem. | pmid:3083043 |
| Nahata MC | Selection of an erythromycin for the treatment of pertussis. | 1988 | Drug Intell Clin Pharm | pmid:3069427 |
| Demediuk P et al. | Traumatic brain injury in the rat: effects on lipid metabolism, tissue magnesium, and water content. | 1988 | J. Neurotrauma | pmid:3066912 |
| Hoppe JE and Haug A | Treatment and prevention of pertussis by antimicrobial agents (Part II). | 1988 May-Jun | Infection | pmid:3042626 |
| Imai A and Gershengorn MC | Measurement of lipid turnover in response to thyrotropin-releasing hormone. | 1987 | Meth. Enzymol. | pmid:3037241 |
| Kringsholm B and Christoffersen P | The nature and the occurrence of birefringent material in different organs in fatal drug addiction. | 1987 May-Jun | Forensic Sci. Int. | pmid:3036675 |
| Faden AI et al. | Alterations in lipid metabolism, Na+,K+-ATPase activity, and tissue water content of spinal cord following experimental traumatic injury. | 1987 | J. Neurochem. | pmid:3033150 |
| Crosby T et al. | Identification of ecdysone 22-long-chain fatty acyl esters in newly laid eggs of the cattle tick Boophilus microplus. | 1986 | Biochem. J. | pmid:3030275 |
| Mazière C et al. | Cyclic AMP increases incorporation of exogenous fatty acids into triacylglycerols in hamster fibroblasts. | 1986 | Lipids | pmid:3020335 |
| Yoshida S et al. | Cerebral phosphoinositide, triacylglycerol, and energy metabolism in reversible ischemia: origin and fate of free fatty acids. | 1986 | J. Neurochem. | pmid:3016186 |
| Mock T et al. | Effects of fatty acids on phosphatidylcholine biosynthesis in isolated hamster heart. | 1986 | Biochem. Cell Biol. | pmid:3013250 |
| Yasuda H et al. | Biphasic liberation of arachidonic and stearic acids during cerebral ischemia. | 1985 | J. Neurochem. | pmid:2987409 |
| Rendu F et al. | Platelet membrane molecular organization: relationship with membrane bound calcium. | 1985 | Biochem. Biophys. Res. Commun. | pmid:2983699 |
| Canonico PL et al. | Arachidonate stimulates prolactin release in vitro: a role for the fatty acid and its metabolites as intracellular regulator(s) in mammotrophs. | 1985 | Endocrinology | pmid:2981065 |
| Shani J et al. | Efficacy of sustained-release radioprotective drugs in vivo. | 1987 Nov-Dec | Z. Naturforsch., C, J. Biosci. | pmid:2966504 |
| West AA et al. | The relationship between glycosyltransferase production and membrane fatty acid composition of Streptococcus sanguis NCTC 7865 grown in the presence of protonmotive force inhibitors. | 1987 | J. Gen. Microbiol. | pmid:2966234 |
| Marchut E et al. | The inhibitory effect of various fatty acids on aerobic glycolysis in Ehrlich ascites tumour cells. | 1986 | Acta Biochim. Pol. | pmid:2940781 |
| Matsuura T et al. | Effect of Alcohols on the Phase Behavior and Emulsification of a Sucrose Fatty Acid Ester/Water/Edible Oil System. | 2018 | J Oleo Sci | pmid:29367483 |
| Enk L et al. | High-dose depot-medroxyprogesterone acetate--effects on the fatty acid composition of serum lecithin and cholesterol ester. | 1985 | Gynecol. Oncol. | pmid:2933308 |
| Noy N and Zakim D | Fatty acids bound to unilamellar lipid vesicles as substrates for microsomal acyl-CoA ligase. | 1985 | Biochemistry | pmid:2931113 |
| Hosaka S and Tokunaga Y | Differences in Powder Properties of Two 1,4-Dihydropyridine-Type Compounds Evaluated through Thermal Analysis. | 2017 | Chem. Pharm. Bull. | pmid:29199222 |
| Pantub K et al. | Preparation of Salicylic Acid Loaded Nanostructured Lipid Carriers Using Box-Behnken Design: Optimization, Characterization and Physicochemical Stability. | 2017 | J Oleo Sci | pmid:29199206 |
| Houghton SC et al. | Intake of dietary fat and fat subtypes and risk of premenstrual syndrome in the Nurses' Health Study II. | 2017 | Br. J. Nutr. | pmid:29189192 |
| Yuan M et al. | Effect of A-317491 delivered by glycolipid-like polymer micelles on endometriosis pain. | 2017 | Int J Nanomedicine | pmid:29184406 |
| Collins JM and Grogan WM | Comparison between flow cytometry and fluorometry for the kinetic measurement of membrane fluidity parameters. | 1989 | Cytometry | pmid:2917474 |
| Friedman E et al. | Fecal diglycerides as selective endogenous mitogens for premalignant and malignant human colonic epithelial cells. | 1989 | Cancer Res. | pmid:2910475 |
| Yamamoto K et al. | Effect of Magnesium Stearate Mono- and Dihydrate Dispersibilities on Physical Properties of Tablets. | 2017 | Chem. Pharm. Bull. | pmid:29093289 |
| Baichwal AR and Augsburger LL | Variations in the friction coefficients of tablet lubricants and relationship to their physicochemical properties. | 1988 | J. Pharm. Pharmacol. | pmid:2907013 |
| Van Rafelghem MJ and Andersen ME | The effects of perfluorodecanoic acid on hepatic stearoyl-coenzyme A desaturase and mixed function oxidase activities in rats. | 1988 | Fundam Appl Toxicol | pmid:2906022 |
| Jones RE and Plymate SR | Evidence for the regulation of fatty acid utilization in human sperm by docosahexaenoic acid. | 1988 | Biol. Reprod. | pmid:2905175 |
| Beg S et al. | QbD-driven development and evaluation of nanostructured lipid carriers (NLCs) of Olmesartan medoxomil employing multivariate statistical techniques. | 2018 | Drug Dev Ind Pharm | pmid:29048242 |
| Soliman HM et al. | Synthesis and Application of a New Amphiphilic Antioxidant. | 2017 | J Oleo Sci | pmid:29021490 |
| Avila P et al. | Which salt of erythromycin is most hepatotoxic? | 1988 | Lancet | pmid:2896928 |
| Liu W and Lu G | Partial Hydrogenation of Sunflower Oil-derived FAMEs Catalyzed by the Efficient and Recyclable Palladium Nanoparticles in Polyethylene Glycol. | 2017 | J Oleo Sci | pmid:28924078 |
| Zara GP et al. | Erythromycin and gastrointestinal motility. | 1987 | Lancet | pmid:2889954 |
| Spigoni V et al. | Stearic acid at physiologic concentrations induces in vitro lipotoxicity in circulating angiogenic cells. | 2017 | Atherosclerosis | pmid:28892713 |
| Kondo H et al. | Effect of the External Lubrication Method for a Rotary Tablet Press on the Adhesion of the Film Coating Layer. | 2017 | Chem. Pharm. Bull. | pmid:28867712 |
| Bergquist SO et al. | Erythromycin in the treatment of pertussis: a study of bacteriologic and clinical effects. | 1987 | Pediatr. Infect. Dis. J. | pmid:2885802 |
| Hattori T et al. | Membrane phospholipid composition and membrane fluidity of human brain tumour: a spin label study. | 1987 | Neurol. Res. | pmid:2883605 |
| Nakanishi H et al. | Comparative studies on additive effects of sodium dodecylbenzensulfonate and sodium stearate on uptake of chemicals by willow shiner (Gnathopogon caerulescens). | 1987 | Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. | pmid:2882933 |
| Fatemi SH et al. | The glycophospholipid anchor of Thy-1. Biosynthetic labeling experiments with wild-type and class E Thy-1 negative lymphomas. | 1987 | J. Biol. Chem. | pmid:2881925 |
| Gotoh K et al. | Effects of unsaturated fatty acids on the peroxisomal enzyme activities of Tetrahymena pyriformis. | 1986 | J. Biochem. | pmid:2880840 |
| Xue J et al. | A novel and organic solvent-free preparation of solid lipid nanoparticles using natural biopolymers as emulsifier and stabilizer. | 2017 | Int J Pharm | pmid:28802794 |
| Lapham DP and Lapham JL | Gas adsorption on commercial magnesium stearate: Effects of degassing conditions on nitrogen BET surface area and isotherm characteristics. | 2017 | Int J Pharm | pmid:28779986 |
| Shiino K et al. | Melt Adsorption as a Manufacturing Method for Fine Particles of Wax Matrices without Any Agglomerates. | 2017 | Chem. Pharm. Bull. | pmid:28768926 |
| Catalá A | Stearic acid desaturation in rat liver microsomes: stimulation by fatty acid binding protein. | 1986 | Acta Physiol Pharmacol Latinoam | pmid:2876583 |
| Giudici TA et al. | Methylmalonic and propionic acidemias: lipid profiles of normal and affected human skin fibroblasts incubated with [1-14C]propionate. | 1986 | Biochem. Med. Metab. Biol. | pmid:2872907 |
| Nagy B et al. | In-line Raman spectroscopic monitoring and feedback control of a continuous twin-screw pharmaceutical powder blending and tableting process. | 2017 | Int J Pharm | pmid:28723408 |
| Hattori T et al. | Attenuation by pentobarbital of free fatty acid and diacylglycerol liberation during global ischaemia in rat brain. | 1986 | Neurol. Res. | pmid:2871507 |
| Meng Y et al. | Stearic acid suppresses mammary gland development by inhibiting PI3K/Akt signaling pathway through GPR120 in pubertal mice. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28712865 |
| Thiel WJ and Sberna FJ | Fluidized bed film coating of an interactive powder mixture to produce microencapsulated 2-5 microns particles. | 1986 | J. Pharm. Pharmacol. | pmid:2871149 |
| Tabachnick M and Korcek L | Effect of long-chain fatty acids on the binding of thyroxine and triiodothyronine to human thyroxine-binding globulin. | 1986 | Biochim. Biophys. Acta | pmid:2869786 |
| Johansson ME and Nicklasson M | Investigation of the film formation of magnesium stearate by applying a flow-through dissolution technique. | 1986 | J. Pharm. Pharmacol. | pmid:2869127 |
| Siegel I et al. | Inhibition of sperm motility and agglutination of sperm cells by free fatty acids in whole semen. | 1986 | Fertil. Steril. | pmid:2868925 |
| Ivanova EP et al. | Bactericidal activity of self-assembled palmitic and stearic fatty acid crystals on highly ordered pyrolytic graphite. | 2017 | Acta Biomater | pmid:28688988 |
| Prasinou P et al. | Fatty acid-based lipidomics and membrane remodeling induced by apoE3 and apoE4 in human neuroblastoma cells. | 2017 | Biochim Biophys Acta Biomembr | pmid:28688796 |
| Staniforth JN | Relationship between particle packing and the physical stability of powder mixes. | 1985 | J. Pharm. Pharmacol. | pmid:2867136 |
| Johansson ME | Influence of the granulation technique and starting material properties on the lubricating effect of granular magnesium stearate. | 1985 | J. Pharm. Pharmacol. | pmid:2867134 |
| Crutchley DJ | Hydroxyeicosatetraenoic acids and other unsaturated fatty acids inhibit endotoxin-induced thromboplastin activity in human monocytes. | 1985 | Biochem. Biophys. Res. Commun. | pmid:2865954 |
| Tse AG et al. | A glycophospholipid tail at the carboxyl terminus of the Thy-1 glycoprotein of neurons and thymocytes. | 1985 | Science | pmid:2865810 |
| Oki E et al. | Polymorphisms of the TNF-α gene interact with plasma fatty acids on inflammatory biomarker profile: a population-based, cross-sectional study in São Paulo, Brazil. | 2017 | Br. J. Nutr. | pmid:28633686 |
| Naing C and Whittaker MA | Anabolic steroids for treating pressure ulcers. | 2017 | Cochrane Database Syst Rev | pmid:28631809 |
| Bangudu AB and Pilpel N | Effects of composition, moisture and stearic acid on the plasto-elasticity and tableting of paracetamol-microcrystalline cellulose mixtures. | 1985 | J. Pharm. Pharmacol. | pmid:2862234 |
| Zoeller RA and Wood R | The importance of the stearoyl-CoA desaturase system in octadecenoate metabolism in the Morris hepatoma 7288C. | 1985 | Biochim. Biophys. Acta | pmid:2860925 |
| Esezobo S | The effect of some excipients on the physical properties of a paracetamol tablet formulation. | 1985 | J. Pharm. Pharmacol. | pmid:2858567 |
| Ragnarsson G and Sjögren J | Force-displacement measurements in tableting. | 1985 | J. Pharm. Pharmacol. | pmid:2858558 |
| Wang XH et al. | High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2. | 2017 | Front Pharmacol | pmid:28555106 |
| Wang Y et al. | Docosahexaenoyl serotonin emerges as most potent inhibitor of IL-17 and CCL-20 released by blood mononuclear cells from a series of N-acyl serotonins identified in human intestinal tissue. | 2017 | Biochim. Biophys. Acta | pmid:28526351 |
| Cosenza G et al. | A novel polymorphism in the oxytocin receptor encoding gene (OXTR) affects milk fatty acid composition in Italian Mediterranean river buffalo. | 2017 | J. Dairy Res. | pmid:28524009 |
| Soni K et al. | Lipid drug conjugate nanoparticle as a potential nanocarrier for the oral delivery of pemetrexed diacid: Formulation design, characterization, ex vivo, and in vivo assessment. | 2017 | Int. J. Biol. Macromol. | pmid:28499946 |
| Chitprasert P and Ngamekaue N | Stability Enhancement of Ocimum Sanctum Linn. Essential Oils Using Stearic Acid in Aluminum Carboxymethyl Cellulose Film-Coated Gelatin Microcapsules. | 2017 | J. Food Sci. | pmid:28494101 |
| Hoeg JM et al. | Apolipoprotein B synthesized by Hep G2 cells undergoes fatty acid acylation. | 1988 | J. Lipid Res. | pmid:2846736 |
| Chang C et al. | pH-responsive nanoparticle assembly from peptide amphiphiles for tumor targeting drug delivery. | 2017 | J Biomater Sci Polym Ed | pmid:28467173 |
| Shilpi D et al. | Improved Stability and Enhanced Oral Bioavailability of Atorvastatin Loaded Stearic Acid Modified Gelatin Nanoparticles. | 2017 | Pharm. Res. | pmid:28466393 |
| Lakhssassi N et al. | Stearoyl-Acyl Carrier Protein Desaturase Mutations Uncover an Impact of Stearic Acid in Leaf and Nodule Structure. | 2017 | Plant Physiol. | pmid:28461402 |
| Hara A et al. | Human carbonyl reductase 1 participating in intestinal first-pass drug metabolism is inhibited by fatty acids and acyl-CoAs. | 2017 | Biochem. Pharmacol. | pmid:28450226 |