stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Ricci M et al. Growth and Dissolution of Calcite in the Presence of Adsorbed Stearic Acid. 2015 Langmuir pmid:26087312
Santos IC et al. Paired-ion electrospray ionization--triple quadrupole tandem mass spectrometry for quantification of anionic surfactants in waters. 2015 Talanta pmid:26078166
Rizzuti B et al. Fatty acid binding into the highest affinity site of human serum albumin observed in molecular dynamics simulation. 2015 Arch. Biochem. Biophys. pmid:26048999
Cárdenas V et al. Strategy for design NIR calibration sets based on process spectrum and model space: An innovative approach for process analytical technology. 2015 J Pharm Biomed Anal pmid:26001330
de Sousa FF et al. Low-temperature phase transformation studies in the stearic acid: C form. 2015 Spectrochim Acta A Mol Biomol Spectrosc pmid:25909902
Patil H et al. Formulation and development of pH-independent/dependent sustained release matrix tablets of ondansetron HCl by a continuous twin-screw melt granulation process. 2015 Int J Pharm pmid:25863118
Bera H et al. Alginate gel-coated oil-entrapped alginate-tamarind gum-magnesium stearate buoyant beads of risperidone. 2015 Int. J. Biol. Macromol. pmid:25861741
Badal Tejedor M et al. Tablet mechanics depend on nano and micro scale adhesion, lubrication and structure. 2015 Int J Pharm pmid:25841569
Yi HX et al. Effect of anionic PEGylated polypeptide on gene transfection mediated by glycolipid conjugate micelles. 2015 Mol. Pharm. pmid:25490413
Leonardi A et al. Cationic solid lipid nanoparticles enhance ocular hypotensive effect of melatonin in rabbit. 2015 Int J Pharm pmid:25448580
Bootello MA et al. Effect of solvents on the fractionation of high oleic-high stearic sunflower oil. 2015 Food Chem pmid:25442612
Thakral NK et al. Compression-induced crystallization of amorphous indomethacin in tablets: characterization of spatial heterogeneity by two-dimensional X-ray diffractometry. 2015 Mol. Pharm. pmid:25438193
Liu Z et al. Process optimization and kinetic evaluation for biosynthesis of D-isoascorbyl stearate. 2015 Bioprocess Biosyst Eng pmid:25407728
Askari M et al. Tissue fatty acid composition and secretory phospholipase-A2 activity in oral squamous cell carcinoma. 2015 Clin Transl Oncol pmid:25351172
Momoh MA et al. Influence of magnesium stearate on the physicochemical and pharmacodynamic characteristics of insulin-loaded Eudragit entrapped mucoadhesive microspheres. 2015 Drug Deliv pmid:24670092
Mohanty B et al. Development and characterization of itraconazole-loaded solid lipid nanoparticles for ocular delivery. 2015 Pharm Dev Technol pmid:24490828
Guadalupe Sánchez-González E et al. The influence of polymorphism on the manufacturability and in vitro dissolution of sulindac-containing hard gelatin capsules. 2015 Pharm Dev Technol pmid:24417644
Van Hoeck V et al. Interaction between differential gene expression profile and phenotype in bovine blastocysts originating from oocytes exposed to elevated non-esterified fatty acid concentrations. 2015 Reprod. Fertil. Dev. pmid:24360349
Miyazaki Y et al. Dry Powder Coating using Planetary Centrifugal Mixer. 2015 J Pharm Pharm Sci pmid:26517137
Imran M and Nadeem M Triacylglycerol composition, physico-chemical characteristics and oxidative stability of interesterified canola oil and fully hydrogenated cottonseed oil blends. 2015 Lipids Health Dis pmid:26510410
Conde-Sieira M et al. Hypothalamic fatty acid sensing in Senegalese sole (Solea senegalensis): response to long-chain saturated, monounsaturated, and polyunsaturated (n-3) fatty acids. 2015 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:26468264
Iwao Y [Efficient Pharmaceutical Formulation Designs and Their Development Using Mathematical and Statistical Analysis]. 2015 Yakugaku Zasshi pmid:26423868
Liu Z et al. A novel stearic acid-modified hirudin peptidomimetic with improved pharmacokinetic properties and anticoagulant activity. 2015 Sci Rep pmid:26400022
Miao H et al. Stearic acid induces proinflammatory cytokine production partly through activation of lactate-HIF1α pathway in chondrocytes. 2015 Sci Rep pmid:26271607
Soliman HM et al. Utilization of Stearic acid Extracted from Olive Pomace for Production of Triazoles, Thiadiazoles and Thiadiazines Derivatives of Potential Biological Activities. 2015 J Oleo Sci pmid:26250422
Veselỳ M et al. Photocatalytic and Antimicrobial Activity of Printed Hybrid Titania/Silica Layers. 2015 J Nanosci Nanotechnol pmid:26716211
Dong X et al. [Analysis of meibum by gas chromatography-mass spectrometry]. 2015 Zhonghua Yan Ke Za Zhi pmid:26693651
Sasakura D et al. Application of the quantitative detection of a change in concentration of magnesium stearate in a feeder tube of tableting manufacture by real-time near-infrared spectroscopy. 2015 Pharmazie pmid:26601418
Li Y et al. Effects of sustained-release composite on the oxygen levels and sediment phosphorus fractions of an urban river in Shanghai. 2014 Sep-Oct Environ Technol pmid:25145170
Mu L et al. Erythrocyte saturated fatty acids and systemic inflammation in adults. 2014 Nov-Dec Nutrition pmid:25280420
Tsukada G et al. Temperature triggered shape memory effect of transpolyisoprene-based polymer. 2014 J Endod pmid:25260740
Pandey P et al. Excipient-process interactions and their impact on tablet compaction and film coating. 2014 J Pharm Sci pmid:25223603
Kushner J and Schlack H Commercial scale validation of a process scale-up model for lubricant blending of pharmaceutical powders. 2014 Int J Pharm pmid:25152166
Mateo-Ortiz D et al. Analysis of powder phenomena inside a Fette 3090 feed frame using in-line NIR spectroscopy. 2014 J Pharm Biomed Anal pmid:25128874
Horio T et al. Effect of particle shape on powder flowability of microcrystalline cellulose as determined using the vibration shear tube method. 2014 Int J Pharm pmid:25079435
Yodkhum K and Phaechamud T Hydrophobic chitosan sponges modified by aluminum monostearate and dehydrothermal treatment as sustained drug delivery system. 2014 Mater Sci Eng C Mater Biol Appl pmid:25063173
Petridis L et al. Spatial arrangement of organic compounds on a model mineral surface: implications for soil organic matter stabilization. 2014 Environ. Sci. Technol. pmid:24328330
Mandal S et al. Enhancement of survival of alginate-encapsulated Lactobacillus casei NCDC 298. 2014 J. Sci. Food Agric. pmid:24307185
Pavićević ID et al. Fatty acids binding to human serum albumin: Changes of reactivity and glycation level of Cysteine-34 free thiol group with methylglyoxal. 2014 Chem. Biol. Interact. pmid:25451573
Maghsoodi M Floating-pulsatile release multiparticulate system for chronopharmacotherapy: effect of some hydrophobic additives on the buoyancy and release behavior of particles. 2014 Drug Res (Stuttg) pmid:23950100
Gouk SW et al. Stearic acids at sn-1, 3 positions of TAG are more efficient at limiting fat deposition than palmitic and oleic acids in C57BL/6 mice. 2014 Br. J. Nutr. pmid:24286356
Díaz R et al. Identification of fatty acids in canine seminal plasma. 2014 Andrologia pmid:23398451
Eiras CE et al. Glycerine levels in the diets of crossbred bulls finished in feedlot: carcass characteristics and meat quality. 2014 Meat Sci. pmid:24211551
Yee JK et al. High oleic/stearic fatty-acid desaturation index in cord plasma from infants of mothers with gestational diabetes. 2014 J Perinatol pmid:24577432
Maretti E et al. Inhaled Solid Lipid Microparticles to target alveolar macrophages for tuberculosis. 2014 Int J Pharm pmid:24374224
Samanta AK et al. Energy-based analysis of cone milling process for the comminution of roller compacted flakes. 2014 Int J Pharm pmid:24374608
Doig M et al. Structure and friction of stearic acid and oleic acid films adsorbed on iron oxide surfaces in squalane. 2014 Langmuir pmid:24364665
Sertoglu E et al. Comparison of plasma and erythrocyte membrane fatty acid compositions in patients with end-stage renal disease and type 2 diabetes mellitus. 2014 Chem. Phys. Lipids pmid:24384240
Khodadoust S et al. Identification and determination of the fatty acid composition of Quercus brantii growing in southwestern Iran by GC-MS. 2014 Nat. Prod. Res. pmid:24499169
Wu MH et al. A novel sodium N-fatty acyl amino acid surfactant using silkworm pupae as stock material. 2014 Sci Rep pmid:24651079