| MeSH term | MeSH ID | Detail |
|---|---|---|
| Obesity, Abdominal | D056128 | 3 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Matsuura T et al. | Effect of Alcohols on the Phase Behavior and Emulsification of a Sucrose Fatty Acid Ester/Water/Edible Oil System. | 2018 | J Oleo Sci | pmid:29367483 |
| Beg S et al. | QbD-driven development and evaluation of nanostructured lipid carriers (NLCs) of Olmesartan medoxomil employing multivariate statistical techniques. | 2018 | Drug Dev Ind Pharm | pmid:29048242 |
| Liu Q et al. | Genetic enhancement of palmitic acid accumulation in cotton seed oil through RNAi down-regulation of ghKAS2 encoding β-ketoacyl-ACP synthase II (KASII). | 2017 | Plant Biotechnol. J. | pmid:27381745 |
| Houghton SC et al. | Intake of dietary fat and fat subtypes and risk of premenstrual syndrome in the Nurses' Health Study II. | 2017 | Br. J. Nutr. | pmid:29189192 |
| Yamamoto K et al. | Effect of Magnesium Stearate Mono- and Dihydrate Dispersibilities on Physical Properties of Tablets. | 2017 | Chem. Pharm. Bull. | pmid:29093289 |
| Soliman HM et al. | Synthesis and Application of a New Amphiphilic Antioxidant. | 2017 | J Oleo Sci | pmid:29021490 |
| Meng Y et al. | Stearic acid suppresses mammary gland development by inhibiting PI3K/Akt signaling pathway through GPR120 in pubertal mice. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28712865 |
| Prasinou P et al. | Fatty acid-based lipidomics and membrane remodeling induced by apoE3 and apoE4 in human neuroblastoma cells. | 2017 | Biochim Biophys Acta Biomembr | pmid:28688796 |
| Oki E et al. | Polymorphisms of the TNF-α gene interact with plasma fatty acids on inflammatory biomarker profile: a population-based, cross-sectional study in São Paulo, Brazil. | 2017 | Br. J. Nutr. | pmid:28633686 |
| Naing C and Whittaker MA | Anabolic steroids for treating pressure ulcers. | 2017 | Cochrane Database Syst Rev | pmid:28631809 |
| Wang Y et al. | Docosahexaenoyl serotonin emerges as most potent inhibitor of IL-17 and CCL-20 released by blood mononuclear cells from a series of N-acyl serotonins identified in human intestinal tissue. | 2017 | Biochim. Biophys. Acta | pmid:28526351 |
| Cosenza G et al. | A novel polymorphism in the oxytocin receptor encoding gene (OXTR) affects milk fatty acid composition in Italian Mediterranean river buffalo. | 2017 | J. Dairy Res. | pmid:28524009 |
| Bayard M et al. | Free fatty acids and their esters modulate isothermal crystallization of anhydrous milk fat. | 2017 | Food Chem | pmid:27719901 |
| Song S et al. | Identification of pork flavour precursors from enzyme-treated lard using Maillard model system assessed by GC-MS and partial least squares regression. | 2017 | Meat Sci. | pmid:27792915 |
| Han Y et al. | Natural variations in stearoyl-acp desaturase genes affect the conversion of stearic to oleic acid in maize kernel. | 2017 | Theor. Appl. Genet. | pmid:27717956 |
| Narang AS et al. | Assessment of Tablet Surface Hardness by Laser Ablation and Its Correlation With the Erosion Tendency of Core Tablets. | 2017 | J Pharm Sci | pmid:27686683 |
| Qu L et al. | Single-step Coprocessing of Cohesive Powder via Mechanical Dry Coating for Direct Tablet Compression. | 2017 | J Pharm Sci | pmid:27665128 |
| Lau M et al. | Investigation into the Manufacture and Properties of Inhalable High-Dose Dry Powders Produced by Comilling API and Lactose with Magnesium Stearate. | 2017 | AAPS PharmSciTech | pmid:28070849 |
| Zhou Y et al. | An oxygen slow-releasing material and its application in water remediation as oxygen supplier. | 2017 | Environ Technol | pmid:28041538 |
| Kelidari HR et al. | Development and Optimisation of Spironolactone Nanoparticles for Enhanced Dissolution Rates and Stability. | 2017 | AAPS PharmSciTech | pmid:27834054 |