stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Obesity, Abdominal D056128 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
MAHADEVAN S et al. STUDIES ON METABOLISM OF VITAMIN A. 3. THE MODE OF ABSORPTION OF VITAMIN A ESTERS IN THE LIVING RAT. 1963 Biochem. J. pmid:14071526
MAHADEVAN S et al. STUDIES ON METABOLISM OF VITAMIN A. 4. STUDIES ON THE MODE OF ABSORPTION OF VITAMIN A BY RAT INTESTINE IN VITRO. 1963 Biochem. J. pmid:14071527
LEAT WM FATTY ACID COMPOSITION OF THE SERUM LIPIDS OF PIGS GIVEN DIFFERENT AMOUNTS OF LINOLEIC ACID. 1963 Biochem. J. pmid:14097364
TINOCO J et al. LIVER LIPIDS OF CHOLINE-DEFICIENT RATS. 1965 Biochem. J. pmid:14345885
Crosby T et al. Identification of ecdysone 22-long-chain fatty acyl esters in newly laid eggs of the cattle tick Boophilus microplus. 1986 Biochem. J. pmid:3030275
GLASCOCK RF and REINIUS LR Studies on the origin of milk fat. 1. The location of tritium in stearic acid produced by the catalytic addition of tritium to elaidic acid. 1956 Biochem. J. pmid:13315207
Wahle KW and Garton GA Desaturation of stearate by sheep tissue microsomal preparations. 1972 Biochem. J. pmid:4643297
Bruce JS and Salter AM Metabolic fate of oleic acid, palmitic acid and stearic acid in cultured hamster hepatocytes. 1996 Biochem. J. pmid:8670161
Hasegawa K et al. Growth of beta(2)-microglobulin-related amyloid fibrils by non-esterified fatty acids at a neutral pH. 2008 Biochem. J. pmid:18637792
Véret J et al. Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 β-cells. 2011 Biochem. J. pmid:21592087
Yamamoto A and Kawashima Y Perfluorodecanoic acid enhances the formation of oleic acid in rat liver. 1997 Biochem. J. pmid:9230124
Weaire PJ and Kekwick RG The fractionation of the fatty acid synthetase activities of avocado mesocarp plastids. 1975 Biochem. J. pmid:1156381
Foot M et al. Some properties, including the substrate in vivo, of the delta 9-desaturase in Micrococcus cryophilus. 1983 Biochem. J. pmid:6847622
Veit M et al. Cytoplasmic tail length influences fatty acid selection for acylation of viral glycoproteins. 1996 Biochem. J. pmid:8761467
Kemp P and Lander DJ The hydrogenation of gamma-linolenic acid by pure cultures of two rumen bacteria. 1983 Biochem. J. pmid:6318740
Schlame M et al. Relationship between lipid saturation and lipid-protein interaction in liver mitochondria modified by catalytic hydrogenation with reference to cardiolipin molecular species. 1990 Biochem. J. pmid:2154183
Graham A et al. Fatty acid specificity for the synthesis of triacylglycerol and phosphatidylcholine and for the secretion of very-low-density lipoproteins and lysophosphatidylcholine by cultures of rat hepatocytes. 1988 Biochem. J. pmid:3355493
Russell NJ and Harwood JL Changes in the acyl lipid composition of photosynthetic bacteria grown under photosynthetic and non-photosynthetic conditions. 1979 Biochem. J. pmid:115463
Sanchez J et al. Lipase-induced alterations of fatty acid synthesis by subcellular fractions from germinating pea (Pisum sativum L.). 1982 Biochem. J. pmid:7115342
Faas FH and Carter WJ Fatty acid desaturation and microsomal lipid fatty acid composition in experimental hypothyroidism. 1982 Biochem. J. pmid:7181859
Jordan BR and Harwood JL Fatty acid elongation by a particulate fraction from germinating pea. 1980 Biochem. J. pmid:7283974
Faas FH and Carter WJ Fatty-acid desaturation and microsomal lipid fatty-acid composition in experimental hyperthyroidism. 1981 Biochem. J. pmid:7305962
ROOTS BI and JOHNSTON PV LIPIDS OF ISOLATED NEURONS. 1965 Biochem. J. pmid:14342249
Light ND and Bailey AJ Polymeric C-terminal cross-linked material from type-I collagen. A modified method for purification, anomalous behaviour on gel filtration, molecular weight estimation, carbohydrate content and lipid content. 1980 Biochem. J. pmid:7458897
Cardoso CM and De Meis L Modulation by fatty acids of Ca2+ fluxes in sarcoplasmic-reticulum vesicles. 1993 Biochem. J. pmid:7504458
Griffiths G et al. The acylation of sn-glycerol 3-phosphate and the metabolism of phosphatidate in microsomal preparations from the developing cotyledons of safflower (Carthamus tinctorius L.) seed. 1985 Biochem. J. pmid:4052051
Trinchera M et al. Recycling of glucosylceramide and sphingosine for the biosynthesis of gangliosides and sphingomyelin in rat liver. 1990 Biochem. J. pmid:2241913
Doering TL et al. The fatty acids in unremodelled trypanosome glycosyl-phosphatidylinositols. 1994 Biochem. J. pmid:8192662
McIlhinney RA and McGlone K Evidence for a non-myristoylated pool of the 80 kDa protein kinase C substrate of rat brain. 1990 Biochem. J. pmid:2244873
Giudici TA et al. Methylmalonic and propionic acidemias: lipid profiles of normal and affected human skin fibroblasts incubated with [1-14C]propionate. 1986 Biochem. Med. Metab. Biol. pmid:2872907
Lurie E et al. N-(2-hydroxybenzyl)-omega-amino carbonic acids and their derivatives as tools for biochemical and biophysical investigations. 1993 Biochem. Mol. Biol. Int. pmid:8358340
Melik-Nubarov NS et al. Interaction of hydrophobized antiviral antibodies with influenza virus infected MDCK cells. 1993 Biochem. Mol. Biol. Int. pmid:8508145
Ohyama H et al. Age-related differences in synaptosomal membrane fluidity. 1995 Biochem. Mol. Biol. Int. pmid:8653075
Croxtall JD et al. Tamoxifen inhibits growth of oestrogen receptor-negative A549 cells. 1994 Biochem. Pharmacol. pmid:8304964
Erman A et al. Phospholipase A2 inhibitors. Differential inhibition of fatty acid acylation into kidney lipids by mepacrine and p-bromophenacyl bromide. 1983 Biochem. Pharmacol. pmid:6870935
Ondrias K et al. Spin label study of the perturbation effect of the local anaesthetics tetracaine and dibucaine on synaptosomes at pharmacological concentrations. 1987 Biochem. Pharmacol. pmid:2825709
Risé P et al. Differential modulation by simvastatin of the metabolic pathways in the n-9, n-6 and n-3 fatty acid series, in human monocytic and hepatocytic cell lines. 2005 Biochem. Pharmacol. pmid:15763545
Hara A et al. Human carbonyl reductase 1 participating in intestinal first-pass drug metabolism is inhibited by fatty acids and acyl-CoAs. 2017 Biochem. Pharmacol. pmid:28450226
Rendu F et al. Ajoene, the antiplatelet compound derived from garlic, specifically inhibits platelet release reaction by affecting the plasma membrane internal microviscosity. 1989 Biochem. Pharmacol. pmid:2539823
Kerr BD et al. Fatty acid derivatised analogues of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. 2009 Biochem. Pharmacol. pmid:19523458
Bruce JS et al. Desaturation and esterification of palmitic and stearic acids in cultured hepatocytes. 1995 Biochem. Soc. Trans. pmid:7672331
Sherrington EJ et al. Lack of effect of different dietary saturated fatty acids on adipose tissue deposition in the rat. 1996 Biochem. Soc. Trans. pmid:8736816
Kaushik N and Vir S Variations in fatty acid composition of neem seeds collected from the Rajasthan state of India. 2000 Biochem. Soc. Trans. pmid:11171243
Parveez GK et al. Transgenic oil palm: production and projection. 2000 Biochem. Soc. Trans. pmid:11171275
Clouet P et al. Mitochondrial respiration on rumenic and linoleic acids. 2001 Biochem. Soc. Trans. pmid:11356175
Liu Q et al. Genetic modification of cotton seed oil using inverted-repeat gene-silencing techniques. 2000 Biochem. Soc. Trans. pmid:11288706
Rich MR and Evans JS Molecular dynamics simulations of adipocyte lipid-binding protein: effect of electrostatics and acyl chain unsaturation. 1996 Biochemistry pmid:8634281
Pohl J et al. Long-chain fatty acid uptake into adipocytes depends on lipid raft function. 2004 Biochemistry pmid:15065861
Woodward H et al. Isolation, purification, and properties of respiratory mucus glycoproteins. 1982 Biochemistry pmid:7074033
Davis PJ et al. Gel to liquid-crystalline transition temperatures of water dispersions of two pairs of positional isomers of unsaturated mixed-acid phosphatidylcholines. 1981 Biochemistry pmid:7260060