stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Obesity, Abdominal D056128 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Boiret M et al. Setting local rank constraints by orthogonal projections for image resolution analysis: application to the determination of a low dose pharmaceutical compound. 2015 Anal. Chim. Acta pmid:26388474
Veit M and Siche S S-acylation of influenza virus proteins: Are enzymes for fatty acid attachment promising drug targets? 2015 Vaccine pmid:26387429
Kelidari HR et al. Formulation optimization and in vitro skin penetration of spironolactone loaded solid lipid nanoparticles. 2015 Colloids Surf B Biointerfaces pmid:25797482
Seyedi S et al. Improving the physical and moisture barrier properties of Lepidium perfoliatum seed gum biodegradable film with stearic and palmitic acids. 2015 Int. J. Biol. Macromol. pmid:25795389
Vervaeck A et al. Fatty acids for controlled release applications: A comparison between prilling and solid lipid extrusion as manufacturing techniques. 2015 Eur J Pharm Biopharm pmid:26428938
Nandini PT et al. Formulation and evaluation of gemcitabine-loaded solid lipid nanoparticles. 2015 Drug Deliv pmid:24283392
Chen Q et al. Preparation and characterization of glycyrrhetinic acid-modified stearic acid-grafted chitosan micelles. 2015 Artif Cells Nanomed Biotechnol pmid:24093764
Senyilmaz D et al. Regulation of mitochondrial morphology and function by stearoylation of TFR1. 2015 Nature pmid:26214738
Gotoh K et al. Introduction of Atmospheric Pressure Plasma to Aqueous Detergent Processes. 2015 J Oleo Sci pmid:26179001
Astanina K et al. Lipid droplets as a novel cargo of tunnelling nanotubes in endothelial cells. 2015 Sci Rep pmid:26095213