MeSH term | MeSH ID | Detail |
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Obesity, Abdominal | D056128 | 3 associated lipids |
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Eromosele CO and Eromosele IC | Fatty acid compositions of seed oils of Haematostaphis barteri and Ximenia americana. | 2002 | Bioresour. Technol. | pmid:11991081 |
Ali J et al. | Buccoadhesive erodible disk for treatment of oro-dental infections: design and characterisation. | 2002 | Int J Pharm | pmid:11996813 |
Bolwell GP et al. | The apoplastic oxidative burst in response to biotic stress in plants: a three-component system. | 2002 | J. Exp. Bot. | pmid:11997382 |
Alhamami OM | The effects of some physico-chemical factors and pharmaceutical excipients on the bioavailability of nitrofurantoin oily and aqueous suspensions in rats. | 2002 | Drug Dev Ind Pharm | pmid:12026223 |
Dobbins RL et al. | The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats. | 2002 | Diabetes | pmid:12031970 |
Kelly FD et al. | Short-term diets enriched in stearic or palmitic acids do not alter plasma lipids, platelet aggregation or platelet activation status. | 2002 | Eur J Clin Nutr | pmid:12032647 |
Hu PC and Chen BH | Effects of riboflavin and fatty acid methyl esters on cholesterol oxidation during illumination. | 2002 | J. Agric. Food Chem. | pmid:12033831 |
Cozzini P et al. | Simple, intuitive calculations of free energy of binding for protein-ligand complexes. 1. Models without explicit constrained water. | 2002 | J. Med. Chem. | pmid:12036355 |
Ohta N and Hatta I | Interaction among molecules in mixtures of ceramide/stearic acid, ceramide/cholesterol and ceramide/stearic acid/cholesterol. | 2002 | Chem. Phys. Lipids | pmid:12047901 |
Singhal R et al. | Immobilization of urease on poly(N-vinyl carbazole)/stearic acid Langmuir-Blodgett films for application to urea biosensor. | 2002 | Biosens Bioelectron | pmid:12052355 |