MeSH term | MeSH ID | Detail |
---|---|---|
Obesity, Abdominal | D056128 | 3 associated lipids |
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Percival L et al. | A case study of dermatitis based on a collaborative approach between occupational physicians and industrial hygienists. | 1995 | Am Ind Hyg Assoc J | pmid:7856518 |
Wong HG | Potential adverse and allergic reactions from complementary and alternative medicine and dietary supplements. | 2006 | Allergy Asthma Clin Immunol | pmid:20525159 |
de Haan P and Kalsbeek GL | Humoral immune response to some benzylpenicillin preparations. | 1983 | Allergy | pmid:6412583 |
Belluzzi A et al. | Short report: zinc sulphate supplementation corrects abnormal erythrocyte membrane long-chain fatty acid composition in patients with Crohn's disease. | 1994 | Aliment. Pharmacol. Ther. | pmid:8186338 |
GOUERE P | [BIOCHEMICAL ASPECT AND DIETETIC ROLE OF GRAPE SEED OIL]. | 1963 | Aliment Vie | pmid:14135213 |
Hrelia S et al. | In vivo effect of chronic ethanol consumption on the fatty acid composition of phosphatidylinositols in resting and anti-CD3-activated lymphocytes. | 1993 | Alcohol. Clin. Exp. Res. | pmid:8279665 |
Best CA et al. | Method to assess fatty acid ethyl ester binding to albumin. | Alcohol Alcohol. | pmid:16554377 | |
Pirozhkov SV et al. | Effect of chronic consumption of ethanol and vitamin E on fatty acid composition and lipid peroxidation in rat heart tissue. | 1992 Jul-Aug | Alcohol | pmid:1637499 |
Mano T et al. | Proton MR spectroscopy of Sjögren-Larsson's syndrome. | 1999 | AJNR Am J Neuroradiol | pmid:10543638 |
Wang L et al. | Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations. | 2011 | AIDS Res Ther | pmid:21385339 |