stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Qu J et al. Development of marker-free transgenic Jatropha plants with increased levels of seed oleic acid. 2012 Biotechnol Biofuels pmid:22377043
Borbon IA et al. Lack of efficacy of curcumin on neurodegeneration in the mouse model of Niemann-Pick C1. 2012 Pharmacol. Biochem. Behav. pmid:22202649
Harvey KA et al. Trans fatty acids: induction of a pro-inflammatory phenotype in endothelial cells. 2012 Lipids pmid:22684911
Tumen I et al. A therapeutic approach for wound healing by using essential oils of cupressus and juniperus species growing in Turkey. 2012 Evid Based Complement Alternat Med pmid:21941588
de Jong S et al. A semipermanent coating for preventing protein adsorption at physiological pH in kinetic capillary electrophoresis. 2012 Electrophoresis pmid:22899267
Agostini F et al. Supercritical extraction from vinification residues: fatty acids, α-tocopherol, and phenolic compounds in the oil seeds from different varieties of grape. 2012 ScientificWorldJournal pmid:22593706
Brown PN et al. Determination of major phenolic compounds in Echinacea spp. raw materials and finished products by high-performance liquid chromatography with ultraviolet detection: single-laboratory validation matrix extension. 2011 Sep-Oct J AOAC Int pmid:22165004
Tomuta I et al. High-Throughput NIR-Chemometric Method for Meloxicam Assay from Powder Blends for Tableting. 2011 Oct-Dec Sci Pharm pmid:22145112
Nanjwade BK et al. Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs. 2011 Oct-Dec Sci Pharm pmid:22145101
Jelvehgari M et al. Formulation, characterization and in vitro evaluation of theophylline-loaded Eudragit RS 100 microspheres prepared by an emulsion-solvent diffusion/evaporation technique. 2011 Nov-Dec Pharm Dev Technol pmid:20722498
Qu WX et al. Analysis of fatty acids in A. szechenyianum Gay. by microwave-assisted extraction and gas chromatography-mass spectrometry. 2011 May-Jun Phytochem Anal pmid:20848395
Nath B et al. Preparation and in vitro dissolution profile of zidovudine loaded microspheres made of Eudragit RS 100, RL 100 and their combinations. 2011 May-Jun Acta Pol Pharm pmid:21648196
BozdaÄŸ-Pehlivan S et al. Evaluation of drug-excipient interaction in the formulation of celecoxib tablets. 2011 May-Jun Acta Pol Pharm pmid:21648198
Malik K et al. Taste masked microspheres of ofloxacin: formulation and evaluation of orodispersible tablets. 2011 Jul-Sep Sci Pharm pmid:21886910
Zaid AN et al. Formulation and bioequivalence of two valsartan tablets after a single oral administration. 2011 Jan-Mar Sci Pharm pmid:21617777
Shah DA et al. Stability indicating LC-method for estimation of paracetamol and lornoxicam in combined dosage form. 2011 Jan-Mar Sci Pharm pmid:21617776
Sasaki T and Tanaka S Adsorption behavior of some aromatic compounds on hydrophobic magnetite for magnetic separation. 2011 J. Hazard. Mater. pmid:21962863
Mottram AR et al. Fatty acids antagonize bupivacaine-induced I(Na) blockade. 2011 Clin Toxicol (Phila) pmid:21970771
Balducci AG et al. Layered lipid microcapsules for mesalazine delayed-release in children. 2011 Int J Pharm pmid:22001795
Kumar RV and Sinha VR Tailoring of drug delivery of 5-fluorouracil to the colon via a mixed film coated unit system. 2011 Acta Pharm pmid:21945913
Jeon JH et al. Novel lipolytic enzymes identified from metagenomic library of deep-sea sediment. 2011 Evid Based Complement Alternat Med pmid:21845199
Jing F et al. Phylogenetic and experimental characterization of an acyl-ACP thioesterase family reveals significant diversity in enzymatic specificity and activity. 2011 BMC Biochem. pmid:21831316
Severino P et al. Polymorphism, crystallinity and hydrophilic-lipophilic balance of stearic acid and stearic acid-capric/caprylic triglyceride matrices for production of stable nanoparticles. 2011 Colloids Surf B Biointerfaces pmid:21543196
Zhou QT et al. Investigation of the extent of surface coating via mechanofusion with varying additive levels and the influences on bulk powder flow properties. 2011 Int J Pharm pmid:21527321
Manzano E et al. Study of the GC-MS determination of the palmitic-stearic acid ratio for the characterisation of drying oil in painting: La Encarnación by Alonso Cano as a case study. 2011 Talanta pmid:21530791
Prabhakar N et al. Polyaniline Langmuir-Blodgett film based aptasensor for ochratoxin A detection. 2011 Biosens Bioelectron pmid:21514815
Fini A et al. Diclofenac salts, part 6: release from lipid microspheres. 2011 J Pharm Sci pmid:21523784
Dani KG et al. Structural and functional analyses of a saturated acyl ACP thioesterase, type B from immature seed tissue of Jatropha curcas. 2011 Plant Biol (Stuttg) pmid:21489096
Huang HY et al. Co-delivery of anti-vascular endothelial growth factor siRNA and doxorubicin by multifunctional polymeric micelle for tumor growth suppression. 2011 J Biomed Mater Res A pmid:21465641
Hisazumi J et al. Quantification of pharmaceutical polymorphs and prediction of dissolution rate using theophylline tablet by terahertz spectroscopy. 2011 Chem. Pharm. Bull. pmid:21467671
Guntupalli R et al. Phage Langmuir monolayers and Langmuir-Blodgett films. 2011 Colloids Surf B Biointerfaces pmid:20843668
Saeed M et al. Assessment of diffuse transmission and reflection modes in near-infrared quantification, part 2: DIFFuse reflection information depth. 2011 J Pharm Sci pmid:20862671
Broderick PA and Kolodny EH Biosensors for brain trauma and dual laser doppler flowmetry: enoxaparin simultaneously reduces stroke-induced dopamine and blood flow while enhancing serotonin and blood flow in motor neurons of brain, in vivo. 2011 Sensors (Basel) pmid:22346571
Veit M and Thaa B Association of influenza virus proteins with membrane rafts. 2011 Adv Virol pmid:22312341
Wadher KJ et al. Formulation and evaluation of a sustained-release tablets of metformin hydrochloride using hydrophilic synthetic and hydrophobic natural polymers. 2011 Indian J Pharm Sci pmid:22303065
Guan Q et al. Preparation and pharmacokinetics of solid lipid nanoparticles loaded with pueraria flavones. 2011 J Control Release pmid:22195890
Wang K et al. Oxaliplatin-incorporated micelles eliminate both cancer stem-like and bulk cell populations in colorectal cancer. 2011 Int J Nanomedicine pmid:22238509
Du YZ et al. Receptor-mediated gene delivery by folic acid-modified stearic acid-grafted chitosan micelles. 2011 Int J Nanomedicine pmid:21845046
Sathiyaraj S et al. Lornoxicam gastro retentive floating matrix tablets: Design and in vitro evaluation. 2011 J Adv Pharm Technol Res pmid:22171312
Solanki SS and Dahima R Formulation and evaluation of aceclofenac mouth-dissolving tablet. 2011 J Adv Pharm Technol Res pmid:22171305
Negi JS et al. Effect of bioadhesion on initial in vitro buoyancy of effervescent floating matrix tablets of ciprofloxacin HCL. 2011 J Adv Pharm Technol Res pmid:22171304
Stahl J et al. The effect of formulation vehicles on the in vitro percutaneous permeation of ibuprofen. 2011 BMC Pharmacol. pmid:22168832
Sharma S et al. RP-HPLC Method for Simultaneous Estimation of Nitazoxanide and Ofloxacin in Tablets. 2011 Indian J Pharm Sci pmid:22131628
Lavigne JP et al. Propolis can potentialise the anti-adhesion activity of proanthocyanidins on uropathogenic Escherichia coli in the prevention of recurrent urinary tract infections. 2011 BMC Res Notes pmid:22126300
Yin AW and Huang SJ [Research on chemical constituents of xuefu zhuyu decoction]. 2011 Zhong Yao Cai pmid:22372145
Rajpurohit H et al. Hordeum vulgare hull in the design of fast disintegrating tablets. 2011 J Young Pharm pmid:21897660
Patel D et al. Design of Controlled Release Non-erodible Polymeric Matrix Tablet Using Microwave Oven-assisted Sintering Technique. 2011 J Young Pharm pmid:21897655
Huntemann M et al. Complete genome sequence of the thermophilic sulfur-reducer Hippea maritima type strain (MH(2)). 2011 Stand Genomic Sci pmid:21886857
Hu C et al. Simultaneous utilization of glucose and xylose for lipid production by Trichosporon cutaneum. 2011 Biotechnol Biofuels pmid:21864398
Bailey JA et al. Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons. 2011 PLoS ONE pmid:21799757
Véret J et al. Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 β-cells. 2011 Biochem. J. pmid:21592087
Eggerath J et al. EDX-Element Analysis of the In Vitro Effect of Fluoride Oral Hygiene Tablets on Artificial Caries Lesion Formation and Remineralization in Human Enamel. 2011 Open Dent J pmid:21687564
Jeon I et al. Evaluation of roll compaction as a preparation method for hydroxypropyl cellulose-based matrix tablets. 2011 J Pharm Bioallied Sci pmid:21687348
Tong M et al. The effect of Zn-Al-hydrotalcites composited with calcium stearate and β-diketone on the thermal stability of PVC. 2011 Int J Mol Sci pmid:21673921
Feng H et al. Pharmacokinetics study of bio-adhesive tablet of Panax notoginseng saponins. 2011 Int Arch Med pmid:21658246
Elokely KM et al. Fluorescence Spectrometric Determination of Drugs Containing α-Methylene Sulfone/Sulfonamide Functional Groups Using N-Methylnicotinamide Chloride as a Fluorogenic Agent. 2011 Int J Anal Chem pmid:21647288
Ip K et al. Analysis of complex metabolic behavior through pathway decomposition. 2011 BMC Syst Biol pmid:21639889
Ion G et al. Effects of canola and corn oil mimetic on Jurkat cells. 2011 Lipids Health Dis pmid:21631947
Yang J et al. Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: implications on anti-glucagon therapies for diabetes. 2011 BMC Genomics pmid:21631939
Roberts LD et al. The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue. 2011 Genome Biol. pmid:21843327
Chabukswar A et al. Six sigma: process of understanding the control and capability of ranitidine hydrochloride tablet. 2011 J Young Pharm pmid:21607050
Lim J et al. Solution structures of the acyl carrier protein domain from the highly reducing type I iterative polyketide synthase CalE8. 2011 PLoS ONE pmid:21674045
Sahu SK et al. Hydrophobically modified carboxymethyl chitosan nanoparticles targeted delivery of paclitaxel. 2011 J Drug Target pmid:20367067
Nicholls HT et al. Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue. 2011 Diabetes pmid:21378177
Meng Y et al. Two-step synthesis of fatty acid ethyl ester from soybean oil catalyzed by Yarrowia lipolytica lipase. 2011 Biotechnol Biofuels pmid:21366905
Idris AM Screening of conditions controlling spectrophotometric sequential injection analysis. 2011 Chem Cent J pmid:21333024
Ordelheide AM et al. The myocyte expression of adiponectin receptors and PPARδ is highly coordinated and reflects lipid metabolism of the human donors. 2011 Exp Diabetes Res pmid:21331343
Wang Y et al. [Analysis of plasma metabonomics of mini-swines with qi deficiency and blood stasis syndrome due to chronic myocardial ischemia]. 2011 Zhong Xi Yi Jie He Xue Bao pmid:21288451
Islam A and Ehsan A Comparison of suture material and technique of closure of subcutaneous fat and skin in caesarean section. 2011 N Am J Med Sci pmid:22540072
Green CD and Olson LK Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic β-cells by stearoyl-CoA desaturase and Elovl6. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:21266672
Gallardo LA et al. Europium stearate additives delay oxidation of UHMWPE for orthopaedic applications: a pilot study. 2011 Clin. Orthop. Relat. Res. pmid:21153455
Gilani K et al. Development of respirable nanomicelle carriers for delivery of amphotericin B by jet nebulization. 2011 J Pharm Sci pmid:20602350
Liu D et al. Synthesis and characterization of upconverting NaYF4:Er3+, Yb3+ nanocrystals via thermal decomposition of stearate precursor. 2011 J Nanosci Nanotechnol pmid:22413291
Pniewski T et al. Low-dose oral immunization with lyophilized tissue of herbicide-resistant lettuce expressing hepatitis B surface antigen for prototype plant-derived vaccine tablet formulation. 2011 J. Appl. Genet. pmid:21107787
González-Mira E et al. Potential use of nanostructured lipid carriers for topical delivery of flurbiprofen. 2011 J Pharm Sci pmid:20575052
Peter A et al. Relationships between hepatic stearoyl-CoA desaturase-1 activity and mRNA expression with liver fat content in humans. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:21045174
Han L et al. Starch stearate as a novel encapsulation wall material and its effect on oil-water interfacial tension. 2011 J Control Release pmid:22195872
Hayashi Y et al. Modeling of latent structure of indomethacin solid dispersion tablet using Bayesian networks. 2011 Drug Dev Ind Pharm pmid:21702729
Naumowicz M et al. Impedance analysis of complex formation equilibria in phosphatidylcholine bilayers containing decanoic acid or decylamine. 2011 Cell Biochem. Biophys. pmid:21340532
Hsouna AB et al. Chemical composition, cytotoxicity effect and antimicrobial activity of Ceratonia siliqua essential oil with preservative effects against Listeria inoculated in minced beef meat. 2011 Int. J. Food Microbiol. pmid:21601302
Gallardo LA et al. Effect of europium(II) stearate on the mechanical properties and the oxidation resistance of UHMWPE. 2011 J Mech Behav Biomed Mater pmid:21565729
Abdel-Mottaleb MM et al. Lipid nanocapsules for dermal application: a comparative study of lipid-based versus polymer-based nanocarriers. 2011 Eur J Pharm Biopharm pmid:21558002
Yoo JY et al. A randomized controlled trial of oral phosphate binders in the treatment of pseudoxanthoma elasticum. 2011 J. Am. Acad. Dermatol. pmid:21496949
Mužíková J and Eimerová I A study of the compaction process and the properties of tablets made of a new co-processed starch excipient. 2011 Drug Dev Ind Pharm pmid:21469946
Yoshida MI et al. Thermal behavior study and decomposition kinetics of amiodarone hydrochloride under isothermal conditions. 2011 Drug Dev Ind Pharm pmid:21449701
Aardema H et al. Oleic acid prevents detrimental effects of saturated fatty acids on bovine oocyte developmental competence. 2011 Biol. Reprod. pmid:21311036
de Morais e Silva FA et al. Rosacea fulminans in pregnancy with ocular perforation. 2011 J Dtsch Dermatol Ges pmid:21366860
Tuei VC et al. Effects of human serum albumin complexed with free fatty acids on cell viability and insulin secretion in the hamster pancreatic β-cell line HIT-T15. 2011 Life Sci. pmid:21396379
Tsai MJ et al. Oral apomorphine delivery from solid lipid nanoparticles with different monostearate emulsifiers: pharmacokinetic and behavioral evaluations. 2011 J Pharm Sci pmid:20740670
Lee DM et al. Oxidative stress and inflammation in renal patients and healthy subjects. 2011 PLoS ONE pmid:21829457
Lipasek RA et al. Effects of anticaking agents and relative humidity on the physical and chemical stability of powdered vitamin C. 2011 J. Food Sci. pmid:22417544
Süntar I et al. Wound Healing Activity of Rubus sanctus Schreber (Rosaceae): Preclinical Study in Animal Models. 2011 Evid Based Complement Alternat Med pmid:19755505
Stingl JC et al. Protocol for minimizing the risk of metachronous adenomas of the colorectum with green tea extract (MIRACLE): a randomised controlled trial of green tea extract versus placebo for nutriprevention of metachronous colon adenomas in the elderly population. 2011 BMC Cancer pmid:21851602
Yuan H et al. Stearic acid-g-chitosan polymeric micelle for oral drug delivery: in vitro transport and in vivo absorption. 2011 Mol. Pharm. pmid:21138243
Krogmann A et al. Inflammatory response of human coronary artery endothelial cells to saturated long-chain fatty acids. 2011 Microvasc. Res. pmid:21112343
Andaloussi SE et al. Application of PepFect peptides for the delivery of splice-correcting oligonucleotides. 2011 Methods Mol. Biol. pmid:21053143
Yu DG et al. Coaxial electrospinning with organic solvent for controlling the size of self-assembled nanoparticles. 2011 Chem. Commun. (Camb.) pmid:21107459
Das SC et al. Use of surface energy distributions by inverse gas chromatography to understand mechanofusion processing and functionality of lactose coated with magnesium stearate. 2011 Eur J Pharm Sci pmid:21621612
Laverroux S et al. Isomerization of vaccenic acid to cis and trans C18:1 isomers during biohydrogenation by rumen microbes. 2011 Lipids pmid:21706384
Pereira MG et al. Trypanosoma cruzi epimastigotes are able to store and mobilize high amounts of cholesterol in reservosome lipid inclusions. 2011 PLoS ONE pmid:21818313