MeSH term | MeSH ID | Detail |
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Decalcification, Pathologic | D003649 | 1 associated lipids |
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Qu L et al. | Influence of coating material on the flowability and dissolution of dry-coated fine ibuprofen powders. | 2015 | Eur J Pharm Sci | pmid:26215464 |
Hong J et al. | Effects of genetic variants for the swine FABP3, HMGA1, MC4R, IGF2, and FABP4 genes on fatty acid composition. | 2015 | Meat Sci. | pmid:26172243 |
Park JH et al. | Development of DH-I-180-3 loaded lipid nanoparticle for photodynamic therapy. | 2015 | Int J Pharm | pmid:26149935 |
de Paiva EJ et al. | Influence of two different alcohols in the esterification of fatty acids over layered zinc stearate/palmitate. | 2015 | Bioresour. Technol. | pmid:26143001 |
Piantoni P et al. | Milk production responses to dietary stearic acid vary by production level in dairy cattle. | 2015 | J. Dairy Sci. | pmid:25529423 |
Vercruysse J et al. | Use of a continuous twin screw granulation and drying system during formulation development and process optimization. | 2015 | Eur J Pharm Biopharm | pmid:25528462 |
Schrank S et al. | The effect of the drying temperature on the properties of wet-extruded calcium stearate pellets: pellet microstructure, drug distribution, solid state and drug dissolution. | 2015 | Int J Pharm | pmid:25526671 |
Foraita S et al. | Impact of the oxygen defects and the hydrogen concentration on the surface of tetragonal and monoclinic ZrO2 on the reduction rates of stearic acid on Ni/ZrO2. | 2015 | Chemistry | pmid:25504844 |
Yan S et al. | Autoxidated linolenic acid inhibits aflatoxin biosynthesis in Aspergillus flavus via oxylipin species. | 2015 | Fungal Genet. Biol. | pmid:25498164 |
Qu L et al. | Investigation of the potential for direct compaction of a fine ibuprofen powder dry-coated with magnesium stearate. | 2015 | Drug Dev Ind Pharm | pmid:24738790 |