| MeSH term | MeSH ID | Detail |
|---|---|---|
| Decalcification, Pathologic | D003649 | 1 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kiliç T et al. | Fatty acid composition of seeds of some species of Nepeta L. | 2007 | Nat. Prod. Res. | pmid:17487620 |
| Shao Q et al. | Comparison of neurofuzzy logic and decision trees in discovering knowledge from experimental data of an immediate release tablet formulation. | 2007 | Eur J Pharm Sci | pmid:17459671 |
| Kamilya T et al. | Interaction and incorporation of ovalbumin with stearic acid monolayer: Langmuir-Blodgett film formation and deposition. | 2007 | Colloids Surf B Biointerfaces | pmid:17418542 |
| Liu J et al. | Solid lipid nanoparticles loaded with insulin by sodium cholate-phosphatidylcholine-based mixed micelles: preparation and characterization. | 2007 | Int J Pharm | pmid:17428627 |
| Shao Q et al. | Investigation of an artificial intelligence technology--Model trees. Novel applications for an immediate release tablet formulation database. | 2007 | Eur J Pharm Sci | pmid:17452096 |
| He X et al. | Mechanistic study of the effect of roller compaction and lubricant on tablet mechanical strength. | 2007 | J Pharm Sci | pmid:17455360 |
| Yu DG et al. | Tablets with material gradients fabricated by three-dimensional printing. | 2007 | J Pharm Sci | pmid:17497729 |
| Deb S et al. | Langmuir-Blodgett films of p-terphenyl in different matrices: evidence of dual excimer. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17350881 |
| Malhi H et al. | Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity. | 2007 | Gut | pmid:17470478 |
| Barreyro FJ et al. | Transcriptional regulation of Bim by FoxO3A mediates hepatocyte lipoapoptosis. | 2007 | J. Biol. Chem. | pmid:17626006 |
| Fatouros DG et al. | Clinical studies with oral lipid based formulations of poorly soluble compounds. | 2007 | Ther Clin Risk Manag | pmid:18472981 |
| Hamad ML et al. | Drug product characterization by macropixel analysis of chemical images. | 2007 | J Pharm Sci | pmid:17630646 |
| Yuan H et al. | Preparation and characteristics of nanostructured lipid carriers for control-releasing progesterone by melt-emulsification. | 2007 | Colloids Surf B Biointerfaces | pmid:17656075 |
| Kamilya T et al. | Incorporation of ovalbumin within cationic octadecylamine monolayer and a comparative study with zwitterionic DPPC and anionic stearic acid monolayer. | 2007 | J Colloid Interface Sci | pmid:17669414 |
| MuzÃková J and Nováková P | A study of the properties of compacts from silicified microcrystalline celluloses. | 2007 | Drug Dev Ind Pharm | pmid:17654026 |
| Kambayashi Y et al. | Various Molecular Species of Diacylglycerol Hydroperoxide Activate Human Neutrophils via PKC Activation. | 2007 | J Clin Biochem Nutr | pmid:18392102 |
| Idris AM et al. | Experimental design optimization of a sequential injection method for promazine assay in bulk and pharmaceutical formulations. | 2007 | J Autom Methods Manag Chem | pmid:18350124 |
| Lumor SE et al. | Synthesis and characterization of canola oil-stearic acid-based trans-free structured lipids for possible margarine application. | 2007 | J. Agric. Food Chem. | pmid:18052237 |
| Martino PD et al. | The role of several l-HPCs in preventing tablet capping during direct compression of metronidazole. | 2007 | Drug Dev Ind Pharm | pmid:18097804 |
| Patel S et al. | Lubrication potential of magnesium stearate studied on instrumented rotary tablet press. | 2007 | AAPS PharmSciTech | pmid:18181549 |
| You J et al. | High cytotoxicity and resistant-cell reversal of novel paclitaxel loaded micelles by enhancing the molecular-target delivery of the drug. | 2007 | Nanotechnology | pmid:20442465 |
| Luo L et al. | Polyoxyethylene 40 stearate modulates multidrug resistance and enhances antitumor activity of vinblastine sulfate. | 2007 | AAPS J | pmid:18170979 |
| Uzunović A and Vranić E | Effect of magnesium stearate concentration on dissolution properties of ranitidine hydrochloride coated tablets. | 2007 | Bosn J Basic Med Sci | pmid:17848158 |
| Yang DY et al. | Detrimental effects of post-treatment with fatty acids on brain injury in ischemic rats. | 2007 | Neurotoxicology | pmid:17854901 |
| Moore DJ et al. | Infrared spectroscopy and differential scanning calorimetry studies of binary combinations of cis-6-octadecenoic acid and octadecanoic acid. | 2007 | Chem. Phys. Lipids | pmid:17697674 |
| Zhang JQ et al. | Preparation and characterization of solid lipid nanoparticles containing silibinin. | 2007 | Drug Deliv | pmid:17701527 |
| Matsuzaka T et al. | Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance. | 2007 | Nat. Med. | pmid:17906635 |
| Nande VS et al. | Sustained release microspheres of diclofenac sodium using PEGylated rosin derivatives. | 2007 | Drug Dev Ind Pharm | pmid:17891576 |
| Cunha-Filho MS et al. | Compatibility of the antitumoral beta-lapachone with different solid dosage forms excipients. | 2007 | J Pharm Biomed Anal | pmid:17890039 |
| Kusano M et al. | Unbiased characterization of genotype-dependent metabolic regulations by metabolomic approach in Arabidopsis thaliana. | 2007 | BMC Syst Biol | pmid:18028551 |
| Gebauer SK et al. | The diversity of health effects of individual trans fatty acid isomers. | 2007 | Lipids | pmid:17694343 |
| Bhandari KH et al. | Evaluation of physicochemical properties, skin permeation and accumulation profiles of ketorolac fatty ester prodrugs. | 2007 | Biol. Pharm. Bull. | pmid:17978504 |
| Chen Y et al. | Formation of monodisperse and shape-controlled MnO nanocrystals in non-injection synthesis: self-focusing via ripening. | 2007 | J. Am. Chem. Soc. | pmid:17696349 |
| Krzeski P et al. | Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study. | 2007 | Arthritis Res. Ther. | pmid:17958901 |
| Wang X et al. | Phase characterization of indomethacin in binary solid dispersions with PVP VA64 or Myrj 52. | 2007 | Int J Pharm | pmid:17604923 |
| Walden M et al. | The effect of ethanol on the release of opioids from oral prolonged-release preparations. | 2007 | Drug Dev Ind Pharm | pmid:17882730 |
| Dong J et al. | Crystallization of silver carboxylates from sodium carboxylate mixtures. | 2007 | Langmuir | pmid:17567157 |
| Zhang YM et al. | A Pseudomonas aeruginosa transcription factor that senses fatty acid structure. | 2007 | Mol. Microbiol. | pmid:17877713 |
| Raffin RP et al. | Development of HPMC and Eudragit S100 blended microparticles containing sodium pantoprazole. | 2007 | Pharmazie | pmid:17557744 |
| Shen LJ and Wu FL | Nanomedicines in renal transplant rejection--focus on sirolimus. | 2007 | Int J Nanomedicine | pmid:17722509 |
| Cieśliński H et al. | A cold-adapted esterase from psychrotrophic Pseudoalteromas sp. strain 643A. | 2007 | Arch. Microbiol. | pmid:17516048 |
| Morkhade DM et al. | PEGylated rosin derivatives: novel microencapsulating materials for sustained drug delivery. | 2007 | AAPS PharmSciTech | pmid:17622122 |
| Barman S and Vasudevan S | Mixed saturated-unsaturated alkyl-chain assemblies: solid solutions of zinc stearate and zinc oleate. | 2007 | J Phys Chem B | pmid:17441755 |
| Chung DJ et al. | Black cohosh and St. John's wort (GYNO-Plus) for climacteric symptoms. | 2007 | Yonsei Med. J. | pmid:17461529 |
| Bandyopadhyay P and Neeta NS | Evidence for vesicle formation from 1:1 nonionic surfactant span 60 and fatty alcohol mixtures in aqueous ethanol: potential delivery vehicle composition. | 2007 | Colloids Surf B Biointerfaces | pmid:17412571 |
| Crunkhorn S et al. | Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation. | 2007 | J. Biol. Chem. | pmid:17416903 |
| Ishak RA et al. | Preparation, in vitro and in vivo evaluation of stomach-specific metronidazole-loaded alginate beads as local anti-Helicobacter pylori therapy. | 2007 | J Control Release | pmid:17412443 |
| Grice DE et al. | Transcriptional profiling of C57 and DBA strains of mice in the absence and presence of morphine. | 2007 | BMC Genomics | pmid:17367521 |
| Rosenberger TA et al. | Bovine brain diacylglycerol lipase: substrate specificity and activation by cyclic AMP-dependent protein kinase. | 2007 | Lipids | pmid:17393225 |
| Mutch DM et al. | Mobilization of pro-inflammatory lipids in obese Plscr3-deficient mice. | 2007 | Genome Biol. | pmid:17355638 |
| Ramstedt M et al. | Wet chemical silver treatment of endotracheal tubes to produce antibacterial surfaces. | 2007 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:17385236 |
| Celleno L et al. | A Dietary supplement containing standardized Phaseolus vulgaris extract influences body composition of overweight men and women. | 2007 | Int J Med Sci | pmid:17299581 |
| Mutalik S et al. | Preparation, in vitro, preclinical and clinical evaluations of once daily sustained release tablets of aceclofenac. | 2007 | Arch. Pharm. Res. | pmid:17366745 |
| Feldkamp T et al. | Alleviation of fatty acid and hypoxia-reoxygenation-induced proximal tubule deenergization by ADP/ATP carrier inhibition and glutamate. | 2007 | Am. J. Physiol. Renal Physiol. | pmid:17244890 |
| Mayer KM and Shanklin J | Identification of amino acid residues involved in substrate specificity of plant acyl-ACP thioesterases using a bioinformatics-guided approach. | 2007 | BMC Plant Biol. | pmid:17201914 |
| Hefnawy MM et al. | Direct enantiomeric resolution of betaxolol with application to analysis of pharmaceutical products. | 2007 | Anal Chem Insights | pmid:19690633 |
| Sephton MA et al. | Biomedical and forensic applications of combined catalytic hydrogenation-stable isotope ratio analysis. | 2007 | Anal Chem Insights | pmid:19662175 |
| Zhao L et al. | Non-destructive determination of metronidazole powder by using artificial neural networks on short-wavelength NIR spectroscopy. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16920000 |
| Mahomed K et al. | Erythrocyte omega-3, omega-6 and trans fatty acids in relation to risk of preeclampsia among women delivering at Harare Maternity Hospital, Zimbabwe. | 2007 | Physiol Res | pmid:16497090 |
| Eltahlawy H et al. | Evidence for two-step regulation of pheromone biosynthesis by the pheromone biosynthesis-activating neuropeptide in the moth Heliothis virescens. | 2007 | Arch. Insect Biochem. Physiol. | pmid:17294424 |
| Pagliassotti MJ et al. | Insulin protects liver cells from saturated fatty acid-induced apoptosis via inhibition of c-Jun NH2 terminal kinase activity. | 2007 | Endocrinology | pmid:17431009 |
| Ishioka T et al. | Infrared study on annealing effect on conformation of zinc stearate. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16875870 |
| Diakogiannaki E et al. | Mechanisms involved in the cytotoxic and cytoprotective actions of saturated versus monounsaturated long-chain fatty acids in pancreatic beta-cells. | 2007 | J. Endocrinol. | pmid:17641278 |
| Petelska AD et al. | Interfacial tension of the lipid membrane formed from lipid-fatty acid and lipid-amine systems. | 2007 | Bioelectrochemistry | pmid:16713376 |
| Karupaiah T and Sundram K | Effects of stereospecific positioning of fatty acids in triacylglycerol structures in native and randomized fats: a review of their nutritional implications. | 2007 | Nutr Metab (Lond) | pmid:17625019 |
| Chalé-Rush A et al. | Multiple routes of chemosensitivity to free fatty acids in humans. | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:17234892 |
| Maduko CO et al. | Enzymatic interesterification of tripalmitin with vegetable oil blends for formulation of caprine milk infant formula analogs. | 2007 | J. Dairy Sci. | pmid:17235135 |
| Graves EL et al. | Factors affecting the concentration of sphingomyelin in bovine milk. | 2007 | J. Dairy Sci. | pmid:17235147 |
| Mosley SA et al. | Effect of varying levels of fatty acids from palm oil on feed intake and milk production in Holstein cows. | 2007 | J. Dairy Sci. | pmid:17235176 |
| Mehrotra A et al. | Influence of shear intensity and total shear on properties of blends and tablets of lactose and cellulose lubricated with magnesium stearate. | 2007 | Int J Pharm | pmid:17236729 |
| Sae-be P et al. | Analysis of the products from enzymatic scouring of cotton. | 2007 | Biotechnol J | pmid:17219458 |
| Cheng Y et al. | Studies on the structure and miscibility of mixed Langmuir-Blodgett films of a double-armed dibenzo-18-crown-6 ether with stearic acid. | 2007 | J Colloid Interface Sci | pmid:17207808 |
| Malmberg P et al. | Localization of lipids in the aortic wall with imaging TOF-SIMS. | 2007 | Biochim. Biophys. Acta | pmid:17240191 |
| Stimson L et al. | Stearic acid spin labels in lipid bilayers: insight through atomistic simulations. | 2007 | J Phys Chem B | pmid:17929861 |
| Kositsawat J et al. | The ratio of oleic-to-stearic acid in the prostate predicts biochemical failure after radical prostatectomy for localized prostate cancer. | 2007 | J. Urol. | pmid:17936811 |
| Egashira Y et al. | Dietary protein level and dietary interaction affect quinolinic acid concentration in rats. | 2007 | Int J Vitam Nutr Res | pmid:17896587 |
| Paillard D et al. | Quantification of ruminal Clostridium proteoclasticum by real-time PCR using a molecular beacon approach. | 2007 | J. Appl. Microbiol. | pmid:17897229 |
| Likitlersuang S et al. | The effect of binary mixture composition and magnesium stearate concentration on the Hiestand Tableting Indices and other related mechanical properties. | 2007 | Pharm Dev Technol | pmid:17963153 |
| Wu SD et al. | The role and mechanism of fatty acids in gallstones. | 2007 | HBPD INT | pmid:17690037 |
| Faqih AM et al. | Effect of moisture and magnesium stearate concentration on flow properties of cohesive granular materials. | 2007 | Int J Pharm | pmid:17289312 |
| Cavallari C et al. | Enhanced release of indomethacin from Pvp/stearic acid microcapsules prepared coupling Co-freeze-drying and ultrasound assisted spray-congealing process. | 2007 | Pharm. Res. | pmid:17252191 |
| Subauste AR and Burant CF | Role of FoxO1 in FFA-induced oxidative stress in adipocytes. | 2007 | Am. J. Physiol. Endocrinol. Metab. | pmid:17374693 |
| Koennings S et al. | Influence of wettability and surface activity on release behavior of hydrophilic substances from lipid matrices. | 2007 | J Control Release | pmid:17412444 |
| de la Luz Reus Medina M and Kumar V | Comparative evaluation of powder and tableting properties of low and high degree of polymerization cellulose I and cellulose II excipients. | 2007 | Int J Pharm | pmid:17376616 |
| Tuomasjukka S et al. | Stearic acid is well absorbed from short- and long-acyl-chain triacylglycerol in an acute test meal. | 2007 | Eur J Clin Nutr | pmid:17299476 |
| Weyenberg W et al. | Cytotoxicity of submicron emulsions and solid lipid nanoparticles for dermal application. | 2007 | Int J Pharm | pmid:17300887 |
| Wang ZJ et al. | Stearic acid protects primary cultured cortical neurons against oxidative stress. | 2007 | Acta Pharmacol. Sin. | pmid:17302992 |
| Del Turco S et al. | Parallel decrease of tissue factor surface exposure and increase of tissue factor microparticle release by the n-3 fatty acid docosahexaenoate in endothelial cells. | 2007 | Thromb. Haemost. | pmid:17598015 |
| Kanthimathi M and Dhathathreyan A | Langmuir and Langmuir-Blodgett films of N-(4-octadecyloxy-2-hydroxybenzylidene) derivatives of amino acids. | 2007 | J Colloid Interface Sci | pmid:17306822 |
| Richter K et al. | Localization of fatty acids with selective chain length by imaging time-of-flight secondary ion mass spectrometry. | 2007 | Microsc. Res. Tech. | pmid:17393479 |
| Simi CK and Emilia Abraham T | Hydrophobic grafted and cross-linked starch nanoparticles for drug delivery. | 2007 | Bioprocess Biosyst Eng | pmid:17278045 |
| Vighi E et al. | Re-dispersible cationic solid lipid nanoparticles (SLNs) freeze-dried without cryoprotectors: characterization and ability to bind the pEGFP-plasmid. | 2007 | Eur J Pharm Biopharm | pmid:17368876 |
| Xu B and Yan B | Photophysical properties of novel lanthanide (Tb3+, Dy3+, Eu3+) complexes with long chain para-carboxyphenol ester p-L-benzoate (L=dodecanoyloxy, myristoyloxy, palmitoyloxy and stearoyloxy). | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16815090 |
| Ando M et al. | Development and evaluation of a novel dry-coated tablet technology for pellets as a substitute for the conventional encapsulation technology. | 2007 | Int J Pharm | pmid:17223295 |
| Bacher C et al. | Improving the compaction properties of roller compacted calcium carbonate. | 2007 | Int J Pharm | pmid:17582712 |
| Dubrovin EV et al. | Self-assembly effect during the adsorption of polynucleotides on stearic acid langmuir-blodgett monolayer. | 2007 | Biomacromolecules | pmid:17583947 |
| Wu H et al. | Process analytical technology (PAT): effects of instrumental and compositional variables on terahertz spectral data quality to characterize pharmaceutical materials and tablets. | 2007 | Int J Pharm | pmid:17590292 |
| Jaimini M et al. | Formulation and evaluation of famotidine floating tablets. | 2007 | Curr Drug Deliv | pmid:17269917 |
| Lee J | Nanoscopic friction behavior of pharmaceutical materials. | 2007 | Int J Pharm | pmid:17442509 |
| Yuan H et al. | Studies on oral absorption of stearic acid SLN by a novel fluorometric method. | 2007 | Colloids Surf B Biointerfaces | pmid:17446050 |