| MeSH term | MeSH ID | Detail |
|---|---|---|
| Decalcification, Pathologic | D003649 | 1 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Malhi H et al. | Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity. | 2007 | Gut | pmid:17470478 |
| Barreyro FJ et al. | Transcriptional regulation of Bim by FoxO3A mediates hepatocyte lipoapoptosis. | 2007 | J. Biol. Chem. | pmid:17626006 |
| Fatouros DG et al. | Clinical studies with oral lipid based formulations of poorly soluble compounds. | 2007 | Ther Clin Risk Manag | pmid:18472981 |
| Hamad ML et al. | Drug product characterization by macropixel analysis of chemical images. | 2007 | J Pharm Sci | pmid:17630646 |
| Yuan H et al. | Preparation and characteristics of nanostructured lipid carriers for control-releasing progesterone by melt-emulsification. | 2007 | Colloids Surf B Biointerfaces | pmid:17656075 |
| Matsuzaka T et al. | Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance. | 2007 | Nat. Med. | pmid:17906635 |
| Nande VS et al. | Sustained release microspheres of diclofenac sodium using PEGylated rosin derivatives. | 2007 | Drug Dev Ind Pharm | pmid:17891576 |
| Kusano M et al. | Unbiased characterization of genotype-dependent metabolic regulations by metabolomic approach in Arabidopsis thaliana. | 2007 | BMC Syst Biol | pmid:18028551 |
| Bhandari KH et al. | Evaluation of physicochemical properties, skin permeation and accumulation profiles of ketorolac fatty ester prodrugs. | 2007 | Biol. Pharm. Bull. | pmid:17978504 |
| Nichols KK et al. | Identification of fatty acids and fatty acid amides in human meibomian gland secretions. | 2007 | Invest. Ophthalmol. Vis. Sci. | pmid:17197513 |
| Zhao L et al. | Non-destructive determination of metronidazole powder by using artificial neural networks on short-wavelength NIR spectroscopy. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16920000 |
| Ishioka T et al. | Infrared study on annealing effect on conformation of zinc stearate. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16875870 |
| Petelska AD et al. | Interfacial tension of the lipid membrane formed from lipid-fatty acid and lipid-amine systems. | 2007 | Bioelectrochemistry | pmid:16713376 |
| Mehrotra A et al. | Influence of shear intensity and total shear on properties of blends and tablets of lactose and cellulose lubricated with magnesium stearate. | 2007 | Int J Pharm | pmid:17236729 |
| Sae-be P et al. | Analysis of the products from enzymatic scouring of cotton. | 2007 | Biotechnol J | pmid:17219458 |
| Cheng Y et al. | Studies on the structure and miscibility of mixed Langmuir-Blodgett films of a double-armed dibenzo-18-crown-6 ether with stearic acid. | 2007 | J Colloid Interface Sci | pmid:17207808 |
| Malmberg P et al. | Localization of lipids in the aortic wall with imaging TOF-SIMS. | 2007 | Biochim. Biophys. Acta | pmid:17240191 |
| Nolan LM et al. | Combined effects of iontophoretic and chemical enhancement on drug delivery. II. Transport across human and murine skin. | 2007 | Int J Pharm | pmid:17502130 |
| Tuomasjukka S et al. | Stearic acid is well absorbed from short- and long-acyl-chain triacylglycerol in an acute test meal. | 2007 | Eur J Clin Nutr | pmid:17299476 |
| Weyenberg W et al. | Cytotoxicity of submicron emulsions and solid lipid nanoparticles for dermal application. | 2007 | Int J Pharm | pmid:17300887 |
| Wang ZJ et al. | Stearic acid protects primary cultured cortical neurons against oxidative stress. | 2007 | Acta Pharmacol. Sin. | pmid:17302992 |
| Kanthimathi M and Dhathathreyan A | Langmuir and Langmuir-Blodgett films of N-(4-octadecyloxy-2-hydroxybenzylidene) derivatives of amino acids. | 2007 | J Colloid Interface Sci | pmid:17306822 |
| Richter K et al. | Localization of fatty acids with selective chain length by imaging time-of-flight secondary ion mass spectrometry. | 2007 | Microsc. Res. Tech. | pmid:17393479 |
| Teixeira AC et al. | Phase behaviour of stearic acid-stearonitrile mixtures. A thermodynamic study in bulk and at the air-water interface. | 2006 Nov-Dec | Chem. Phys. Lipids | pmid:17027948 |
| Wang Y and Wu W | In situ evading of phagocytic uptake of stealth solid lipid nanoparticles by mouse peritoneal macrophages. | 2006 May-Jun | Drug Deliv | pmid:16556570 |
| Uematsu Y et al. | Determination of magnesium stearate in capsule- or tablet-type supplements. | 2006 Mar-Apr | J AOAC Int | pmid:16640294 |
| KladnÃcková I et al. | Release of albumin from oligoester plastic matrices: effect of magnesium oxide and bivalent stearates. | 2006 Jan-Feb | Drug Deliv | pmid:16401590 |
| Fang Q et al. | Ascorbyl stearate inhibits cell proliferation and tumor growth in human ovarian carcinoma cells by targeting the PI3K/AKT pathway. | 2006 Jan-Feb | Anticancer Res. | pmid:16475700 |
| Templer J et al. | Influence of C18 long chain fatty acids on hydrogen metabolism. | 2006 Jan-Feb | Biotechnol. Prog. | pmid:16454511 |
| Pillai KG et al. | Spontaneous tooth exfoliation, maxillary osteomyelitis and facial scarring following trigeminal herpes zoster infection. | 2006 | Prim Dent Care | pmid:16836817 |
| Alves M and Peric M | An EPR study of the interfacial properties of phosphatidylcholine vesicles with different lipid chain lengths. | 2006 | Biophys. Chem. | pmid:16517048 |
| You JO et al. | Incorporation of quantum dots on virus in polycationic solution. | 2006 | Int J Nanomedicine | pmid:17722262 |
| Ramirez-Dorronsoro JC et al. | Chargeability measurements of selected pharmaceutical dry powders to assess their electrostatic charge control capabilities. | 2006 | AAPS PharmSciTech | pmid:17285749 |
| Huber AH et al. | Fatty acid-specific fluorescent probes and their use in resolving mixtures of unbound free fatty acids in equilibrium with albumin. | 2006 | Biochemistry | pmid:17128966 |
| Anand M et al. | Synthesis and steric stabilization of silver nanoparticles in neat carbon dioxide solvent using fluorine-free compounds. | 2006 | J Phys Chem B | pmid:16869575 |
| Martinello T et al. | Optimization of poorly compactable drug tablets manufactured by direct compression using the mixture experimental design. | 2006 | Int J Pharm | pmid:16806756 |
| Kapuśniak J and Tomasik P | Lipid microencapsulation in starch. | 2006 | J Microencapsul | pmid:16801245 |
| MacDonald AM and Lucy CA | Highly efficient protein separations in capillary electrophoresis using a supported bilayer/diblock copolymer coating. | 2006 | J Chromatogr A | pmid:16777117 |
| Douliez JP et al. | Self-assembly of fatty acid-alkylboladiamine salts. | 2006 | Langmuir | pmid:16401110 |
| Chen G | An exfoliated polyamide-6/layered double hydroxide nanocomposite via in situ intercalative polymerization between positively charged inorganic platelets. | 2006 | J Nanosci Nanotechnol | pmid:16736781 |
| Okazaki K et al. | The significance of C16 fatty acids in the sn-2 positions of glycerolipids in the photosynthetic growth of Synechocystis sp. PCC6803. | 2006 | Plant Physiol. | pmid:16603667 |
| Raith K et al. | Towards a molecular characterization of pharmaceutical excipients: mass spectrometric studies of ethoxylated surfactants. | 2006 | Int J Pharm | pmid:16730931 |
| Xu L et al. | A new triterpene and dibenzocyclooctadiene lignans from Schisandra propinqua (WALL.) BAILL. | 2006 | Chem. Pharm. Bull. | pmid:16595961 |
| Pérez-Vich B et al. | Molecular analysis of the high stearic acid content in sunflower mutant CAS-14. | 2006 | Theor. Appl. Genet. | pmid:16362273 |
| Urai M et al. | Structural analysis of an extracellular polysaccharide produced by Rhodococcus rhodochrous strain S-2. | 2006 | Carbohydr. Res. | pmid:16676419 |
| Zhu K et al. | Two aerobic pathways for the formation of unsaturated fatty acids in Pseudomonas aeruginosa. | 2006 | Mol. Microbiol. | pmid:16573679 |
| Shibata Y et al. | Fluidity and tableting characteristics of a powder solid dispersion of the low melting drugs ketoprofen and ibuprofen with crospovidone. | 2006 | Drug Dev Ind Pharm | pmid:16638683 |
| Capková P et al. | Structure of montmorillonite cointercalated with stearic acid and octadecylamine: modeling, diffraction, IR spectroscopy. | 2006 | J Colloid Interface Sci | pmid:16631185 |
| Wei Y et al. | Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16492686 |
| Wang Y et al. | Chronic effects of different non-esterified fatty acids on pancreatic islets of rats. | 2006 | Endocrine | pmid:16622307 |
| Khairuzzaman A et al. | Zero-order release of aspirin, theophylline and atenolol in water from novel methylcellulose glutarate matrix tablets. | 2006 | Int J Pharm | pmid:16621361 |
| Wang Y et al. | Chain orientation and headgroup structure in Langmuir monolayers of stearic acid and metal stearate (Ag, Co, Zn, and Pb) studied by infrared reflection-absorption spectroscopy. | 2006 | J Chem Phys | pmid:16613467 |
| Mora PC et al. | Differential scanning calorimetry as a screening technique in compatibility studies of DHEA extended release formulations. | 2006 | J Pharm Biomed Anal | pmid:16574368 |
| Ding EL et al. | Chocolate and prevention of cardiovascular disease: a systematic review. | 2006 | Nutr Metab (Lond) | pmid:16390538 |
| Hasegawa T et al. | Molecular orientation analysis of a single-monolayer Langmuir-Blodgett film on a thin glass plate by infrared multiple-angle incidence resolution spectrometry. | 2006 | Anal. Chem. | pmid:16536405 |
| Serebryakova MV et al. | Mass spectrometric sequencing and acylation character analysis of C-terminal anchoring segment from Influenza A hemagglutinin. | 2006 | Eur J Mass Spectrom (Chichester) | pmid:16531651 |
| Polat M | Kinetic estimation of the adsorbate distribution on the surface from adsorbed amounts. | 2006 | J Colloid Interface Sci | pmid:16445933 |
| Zeman M et al. | N-3 fatty acid supplementation decreases plasma homocysteine in diabetic dyslipidemia treated with statin-fibrate combination. | 2006 | J. Nutr. Biochem. | pmid:16214329 |
| Fernandez-Moya V et al. | Lipid characterization of a high-stearic sunflower mutant displaying a seed stearic acid gradient. | 2006 | J. Agric. Food Chem. | pmid:19127733 |
| Sayari A and Gargouri Y | [Enzymatic synthesis of homogenous triacylglycerol in media without solvent]. | 2006 | Arch Inst Pasteur Tunis | pmid:19388599 |
| Yao HT et al. | The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes. | 2006 | Life Sci. | pmid:16978661 |
| Duan Y et al. | Effect of molecular sieves on lipase-catalyzed esterification of rutin with stearic acid. | 2006 | J. Agric. Food Chem. | pmid:16910711 |
| Kazmierczak SC et al. | Electron spin resonance spectroscopy of serum albumin: a novel new test for cancer diagnosis and monitoring. | 2006 | Clin. Chem. | pmid:16990414 |
| Shankar BV and Patnaik A | J-aggregates in matrix stabilized two-dimensional azobenzene derivatives. | 2006 | J Colloid Interface Sci | pmid:16844137 |
| Miranda LA et al. | Performance of UASB and DAEB reactors in the anaerobic digestion of synthetic wastewater containing sodium oleate and sodium stereate. | 2006 | Water Sci. Technol. | pmid:16939093 |
| Colla E et al. | Amaranthus cruentus flour edible films: influence of stearic acid addition, plasticizer concentration, and emulsion stirring speed on water vapor permeability and mechanical properties. | 2006 | J. Agric. Food Chem. | pmid:16939322 |
| Renaville B et al. | Eicosapentaenoic acid and 3,10 dithia stearic acid inhibit the desaturation of trans-vaccenic acid into cis-9, trans-11-conjugated linoleic acid through different pathways in Caco-2 and T84 cells. | 2006 | Br. J. Nutr. | pmid:16571147 |
| Fukuda S et al. | Augmentation of vaccenate production and suppression of vaccenate biohydrogenation in cultures of mixed ruminal microbes. | 2006 | J. Dairy Sci. | pmid:16507700 |
| Nazzal S and Khan MA | Controlled release of a self-emulsifying formulation from a tablet dosage form: stability assessment and optimization of some processing parameters. | 2006 | Int J Pharm | pmid:16563673 |
| Swaminathan V et al. | Measurement of the surface energy of lubricated pharmaceutical powders by inverse gas chromatography. | 2006 | Int J Pharm | pmid:16469458 |
| Barman S and Vasudevan S | Contrasting melting behavior of zinc stearate and zinc oleate. | 2006 | J Phys Chem B | pmid:16471580 |
| Wang ZJ et al. | Neuroprotective effect of the stearic acid against oxidative stress via phosphatidylinositol 3-kinase pathway. | 2006 | Chem. Biol. Interact. | pmid:16448636 |
| Salles HC et al. | The venomous secrets of the web droplets from the viscid spiral of the orb-weaver spider Nephila clavipes (Araneae, Tetragnatidae). | 2006 | Chem. Biodivers. | pmid:17193305 |
| Ray K et al. | Distance-dependent metal-enhanced fluorescence from Langmuir-Blodgett monolayers of alkyl-NBD derivatives on silver island films. | 2006 | Langmuir | pmid:16981751 |
| Amakura Y et al. | Characteristic long-chain fatty acid of Pleurocybella porrigens. | 2006 | Shokuhin Eiseigaku Zasshi | pmid:16984039 |
| Pleite R et al. | Increase of the stearic acid content in high-oleic sunflower (Helianthus annuus) seeds. | 2006 | J. Agric. Food Chem. | pmid:17147422 |
| John Wallace R et al. | Clostridium proteoclasticum: A ruminal bacterium that forms stearic acid from linoleic acid. | 2006 | FEMS Microbiol. Lett. | pmid:17147764 |
| Hirai N et al. | Improvement of the agitation granulation method to prepare granules containing a high content of a very hygroscopic drug. | 2006 | J. Pharm. Pharmacol. | pmid:17132205 |
| Müller H et al. | Control of CaCO3 crystallization by demixing of monolayers. | 2006 | Langmuir | pmid:17154582 |
| Song GY et al. | High-fat feeding reduces endothelium-dependent vasodilation in rats: differential mechanisms for saturated and unsaturated fatty acids? | 2006 | Clin. Exp. Pharmacol. Physiol. | pmid:16895544 |
| El Hagrasy AS et al. | Evaluation of risk and benefit in the implementation of near-infrared spectroscopy for monitoring of lubricant mixing. | 2006 | Pharm Dev Technol | pmid:16895841 |
| Rasmussen HE et al. | Reduction in cholesterol absorption is enhanced by stearate-enriched plant sterol esters in hamsters. | 2006 | J. Nutr. | pmid:17056791 |
| Brouwer DH et al. | Size selective dustiness and exposure; simulated workplace comparisons. | 2006 | Ann Occup Hyg | pmid:16524926 |
| Biswas S et al. | Formation of complex films with water-soluble CTAB molecules. | 2006 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16549387 |
| Suresh Y and Das UN | Differential effect of saturated, monounsaturated, and polyunsaturated fatty acids on alloxan-induced diabetes mellitus. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16412622 |
| Azevedo-Martins AK et al. | Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells. | 2006 | Toxicol In Vitro | pmid:16644178 |
| iHoroz BB et al. | Influence of aluminum tristearate and sucrose stearate as the dispersing agents on physical properties and release characteristics of eudragit RS microspheres. | 2006 | AAPS PharmSciTech | pmid:16584146 |
| Hu FQ et al. | A novel chitosan oligosaccharide-stearic acid micelles for gene delivery: properties and in vitro transfection studies. | 2006 | Int J Pharm | pmid:16632285 |
| Tsakalof AK et al. | Pitfalls in drying oils identification in art objects by gas chromatography. | 2006 | J Sep Sci | pmid:16922282 |
| Govindarajan R et al. | Ionization states in the microenvironment of solid dosage forms: effect of formulation variables and processing. | 2006 | Pharm. Res. | pmid:16933092 |
| Shen Q et al. | Modulation of intestinal P-glycoprotein function by polyethylene glycols and their derivatives by in vitro transport and in situ absorption studies. | 2006 | Int J Pharm | pmid:16500056 |
| Desrosiers Lachiver E et al. | Insights into the role of electrostatic forces on the behavior of dry pharmaceutical particulate systems. | 2006 | Pharm. Res. | pmid:16715390 |
| Tönges L et al. | Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons. | 2006 | RNA | pmid:16699166 |
| Waterhouse KE et al. | Within and between breed differences in freezing tolerance and plasma membrane fatty acid composition of boar sperm. | 2006 | Reproduction | pmid:16672353 |
| Otsuka M and Yamane I | Prediction of tablet hardness based on near infrared spectra of raw mixed powders by chemometrics. | 2006 | J Pharm Sci | pmid:16721793 |
| Zou T et al. | Support vector regression for determination of component of compound oxytetracycline powder on near-infrared spectroscopy. | 2006 | Anal. Biochem. | pmid:16723110 |
| Planinsek O et al. | Surface analysis of powder binary mixtures with ATR FTIR spectroscopy. | 2006 | Int J Pharm | pmid:16730933 |
| Söderhäll I et al. | Characterization of a hemocyte intracellular fatty acid-binding protein from crayfish (Pacifastacus leniusculus) and shrimp (Penaeus monodon). | 2006 | FEBS J. | pmid:16734719 |
| Hu FQ et al. | Novel self-aggregates of chitosan oligosaccharide grafted stearic acid: preparation, characterization and protein association. | 2006 | Pharmazie | pmid:16599258 |
| Killen BU and Corrigan OI | Effect of soluble filler on drug release from stearic acid based compacts. | 2006 | Int J Pharm | pmid:16600537 |