| MeSH term | MeSH ID | Detail |
|---|---|---|
| Decalcification, Pathologic | D003649 | 1 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sakuma S et al. | The effects of fatty acyl CoA esters on the formation of prostaglandin and arachidonoyl-CoA formed from arachidonic acid in rabbit kidney medulla microsomes. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11161586 |
| Watanabe L et al. | Initiating structural studies of Lys49-PLA2 homologues complexed with an anionic detergent, a fatty acid and a natural lipid. | 2003 | Protein Pept. Lett. | pmid:14561144 |
| Cheng HC et al. | Lipid binding in rice nonspecific lipid transfer protein-1 complexes from Oryza sativa. | 2004 | Protein Sci. | pmid:15295114 |
| Evoli S et al. | Molecular simulations of β-lactoglobulin complexed with fatty acids reveal the structural basis of ligand affinity to internal and possible external binding sites. | 2014 | Proteins | pmid:24916607 |
| Murphy DJ | The extracellular pollen coat in members of the Brassicaceae: composition, biosynthesis, and functions in pollination. | 2006 | Protoplasma | pmid:16937052 |
| McNamara RK et al. | Deficits in docosahexaenoic acid and associated elevations in the metabolism of arachidonic acid and saturated fatty acids in the postmortem orbitofrontal cortex of patients with bipolar disorder. | 2008 | Psychiatry Res | pmid:18715653 |
| Chitapanarux I et al. | Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. | 2010 | Radiat Oncol | pmid:20444243 |
| MIRAS CJ et al. | LIPID BIOSYNTHESIS BY HUMAN BONE MARROW CELL CULTURES AND GAMMA RADIATION. | 1964 | Radiat. Res. | pmid:14201876 |
| Yamamoto O | Radiation-induced crosslinks between carboxylic acids and compounds of biological interest. | 1986 | Radiat. Res. | pmid:3952268 |
| SNYDER F and WRIGHT R | EFFECT OF LOCALIZED IRRADIATION ON THE METABOLISM OF BONE-MARROW LIPIDS. | 1965 | Radiat. Res. | pmid:14295131 |
| Craig OE et al. | Distinguishing wild ruminant lipids by gas chromatography/combustion/isotope ratio mass spectrometry. | 2012 | Rapid Commun. Mass Spectrom. | pmid:22956328 |
| Liu Y et al. | Graphene and graphene oxide: two ideal choices for the enrichment and ionization of long-chain fatty acids free from matrix-assisted laser desorption/ionization matrix interference. | 2011 | Rapid Commun. Mass Spectrom. | pmid:22006384 |
| Xue R et al. | A serum metabolomic investigation on hepatocellular carcinoma patients by chemical derivatization followed by gas chromatography/mass spectrometry. | 2008 | Rapid Commun. Mass Spectrom. | pmid:18767022 |
| Loutelier-Bourhis C et al. | Mechanistic study of maleic anhydride grafting onto fatty double bonds using mass spectrometry. | 2012 | Rapid Commun. Mass Spectrom. | pmid:22555920 |
| Shehab-El-Deen MA et al. | Cryotolerance of bovine blastocysts is affected by oocyte maturation in media containing palmitic or stearic acid. | 2009 | Reprod. Domest. Anim. | pmid:18992093 |
| Renaville B et al. | Plasma and follicular fluid fatty acid profiles in dairy cows. | 2010 | Reprod. Domest. Anim. | pmid:19055554 |
| Van Hoeck V et al. | Interaction between differential gene expression profile and phenotype in bovine blastocysts originating from oocytes exposed to elevated non-esterified fatty acid concentrations. | 2015 | Reprod. Fertil. Dev. | pmid:24360349 |
| Bender K et al. | Metabolite concentrations in follicular fluid may explain differences in fertility between heifers and lactating cows. | 2010 | Reproduction | pmid:20385782 |
| Van Hoeck V et al. | Oocyte developmental failure in response to elevated nonesterified fatty acid concentrations: mechanistic insights. | 2013 | Reproduction | pmid:23108110 |
| Waterhouse KE et al. | Within and between breed differences in freezing tolerance and plasma membrane fatty acid composition of boar sperm. | 2006 | Reproduction | pmid:16672353 |