stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Decalcification, Pathologic D003649 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


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Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Romanowicz L and Bańkowski E Altered sphingolipid composition in Wharton's jelly of pre-eclamptic newborns. 2010 Pathobiology pmid:20332667
Rideout TC et al. Consumption of plant sterols reduces plasma and hepatic triglycerides and modulates the expression of lipid regulatory genes and de novo lipogenesis in C57BL/6J mice. 2010 Mol Nutr Food Res pmid:20333723
Shi X et al. On the coating of precipitated calcium carbonate with stearic acid in aqueous medium. 2010 Langmuir pmid:20334413
Swamy PV et al. Preparation and evaluation of orodispersible tablets of pheniramine maleate by effervescent method. 2009 Indian J Pharm Sci pmid:20336216
van den Berg SA et al. High levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity. 2010 Nutr Metab (Lond) pmid:20346174
Chen JM et al. [Comparison of seed oil physicochemical characteristics among three cultivars of Jatropha curcas L]. 2009 Ying Yong Sheng Tai Xue Bao pmid:20353052
Araújo J et al. Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications. 2010 Int J Pharm pmid:20362042
Sahu SK et al. Hydrophobically modified carboxymethyl chitosan nanoparticles targeted delivery of paclitaxel. 2011 J Drug Target pmid:20367067
Louis J et al. PAD4-dependent antibiosis contributes to the ssi2-conferred hyper-resistance to the green peach aphid. 2010 Mol. Plant Microbe Interact. pmid:20367470
Ospina-E JC et al. Development of combinations of chemically modified vegetable oils as pork backfat substitutes in sausages formulation. 2010 Meat Sci. pmid:20374815
Bender K et al. Metabolite concentrations in follicular fluid may explain differences in fertility between heifers and lactating cows. 2010 Reproduction pmid:20385782
Jithan AV et al. Development and evaluation of a chloramphenicol hypertonic ophthalmic solution. 2008 Indian J Pharm Sci pmid:20390083
Patel DM and Patel MM Optimization of fast dissolving etoricoxib tablets prepared by sublimation technique. 2008 Indian J Pharm Sci pmid:20390084
Baldania SL et al. RP-HPLC Estimation of Venlafaxine Hydrochloride in Tablet Dosage Forms. 2008 Indian J Pharm Sci pmid:20390099
Terekhova EA et al. [Stearic acid methyl ether: a new extracellular metabolite of the obligate methylotrophic bacterium Methylophilus quaylei]. 2010 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:20391761
Howell AB et al. Dosage effect on uropathogenic Escherichia coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content: a multicentric randomized double blind study. 2010 BMC Infect. Dis. pmid:20398248
Pedersen PJ et al. Liposomal formulation of retinoids designed for enzyme triggered release. 2010 J. Med. Chem. pmid:20405849
Gadegbeku CA et al. Insulin's actions on plasma free fatty acids are normal in patients with stage 2 to 3 chronic kidney disease. J Am Soc Hypertens pmid:20409874
Croxton RS et al. Variation in amino acid and lipid composition of latent fingerprints. 2010 Forensic Sci. Int. pmid:20413233
Zhou YY et al. Preparation and pharmacodynamics of stearic acid and poly (lactic-co-glycolic acid) grafted chitosan oligosaccharide micelles for 10-hydroxycamptothecin. 2010 Int J Pharm pmid:20420886
Wu T et al. Study on superhydrophobic hybrids fabricated from multiwalled carbon nanotubes and stearic acid. 2010 J Colloid Interface Sci pmid:20427047
Murate M et al. Phosphatidylglucoside forms specific lipid domains on the outer leaflet of the plasma membrane. 2010 Biochemistry pmid:20433166
Zhou QT et al. Understanding the influence of powder flowability, fluidization and de-agglomeration characteristics on the aerosolization of pharmaceutical model powders. 2010 Eur J Pharm Sci pmid:20433919
Zhou QT et al. Improving aerosolization of drug powders by reducing powder intrinsic cohesion via a mechanical dry coating approach. 2010 Int J Pharm pmid:20435112
Cohn JS et al. Reduction in intestinal cholesterol absorption by various food components: mechanisms and implications. 2010 Atheroscler Suppl pmid:20439167
You J et al. High cytotoxicity and resistant-cell reversal of novel paclitaxel loaded micelles by enhancing the molecular-target delivery of the drug. 2007 Nanotechnology pmid:20442465
Chitapanarux I et al. Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. 2010 Radiat Oncol pmid:20444243
Prossnigg F et al. Packing behaviour of two predominant anionic phospholipids of bacterial cytoplasmic membranes. 2010 Biophys. Chem. pmid:20451316
Sorek N et al. An S-acylation switch of conserved G domain cysteines is required for polarity signaling by ROP GTPases. 2010 Curr. Biol. pmid:20451389
Xu Y et al. Carbon-covered magnetic nanomaterials and their application for the thermolysis of cancer cells. 2010 Int J Nanomedicine pmid:20463932
Karande AD et al. Calibration sampling paradox in near infrared spectroscopy: a case study of multi-component powder blend. 2010 Int J Pharm pmid:20472048
Liu RS and Tang YJ Quantitative analysis for the effect of plant oil and fatty acid on Tuber melanosporum culture by uniform design combined with partial least squares regression. 2010 Appl. Microbiol. Biotechnol. pmid:20473608
El Hadrami A et al. Chitosan in plant protection. 2010 Mar Drugs pmid:20479963
Roni MA et al. Formulation and in vitro Evaluation of Alfuzosin Extended Release Tablets Using Directly Compressible Eudragit. 2009 Indian J Pharm Sci pmid:20490290
Jacob S and Shirwaikar A Preparation and evaluation of microencapsulated fast melt tablets of ambroxol hydrochloride. 2009 Indian J Pharm Sci pmid:20490294
Keny RV et al. Formulation and evaluation of once daily minocycline hydrochloride extended release matrix tablets. 2009 Indian J Pharm Sci pmid:20490297
Arayne MS et al. Spectrophotometric Quantitation of Metformin in Bulk Drug and Pharmaceutical Formulations using Multivariate Technique. 2009 Indian J Pharm Sci pmid:20490308
Barupal DK et al. Hydrocarbon phenotyping of algal species using pyrolysis-gas chromatography mass spectrometry. 2010 BMC Biotechnol. pmid:20492649
Boiron F et al. A comparison of substrate-dependent fatty acyl-CoA synthetase activities and ATP hydrolysis in membrane pellets from normal and trembler mouse sciatic nerves. 1985 Neurochem. Int. pmid:20492990
Contreras GA et al. Lipomobilization in periparturient dairy cows influences the composition of plasma nonesterified fatty acids and leukocyte phospholipid fatty acids. 2010 J. Dairy Sci. pmid:20494158
Mukherjee S et al. Solid lipid nanoparticles: a modern formulation approach in drug delivery system. 2009 Indian J Pharm Sci pmid:20502539
Madgulkar AR et al. Formulation and optimization of sustained release tablets of venlafaxine resinates using response surface methodology. 2009 Indian J Pharm Sci pmid:20502544
Rivera CA et al. Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis. 2010 BMC Gastroenterol pmid:20509914
Kim IS and Oh IJ Preparation and characterization of stearic acid-pullulan nanoparticles. 2010 Arch. Pharm. Res. pmid:20512475
Akihisa T et al. Triterpene alcohol and fatty acid composition of shea nuts from seven African countries. 2010 J Oleo Sci pmid:20513968
Zhu SH et al. [Study on the chemical constituents of Dichrocephala integrifolia]. 2010 Zhong Yao Cai pmid:20518304
Thörn K and Bergsten P Fatty acid-induced oxidation and triglyceride formation is higher in insulin-producing MIN6 cells exposed to oleate compared to palmitate. 2010 J. Cell. Biochem. pmid:20524206
Wong HG Potential adverse and allergic reactions from complementary and alternative medicine and dietary supplements. 2006 Allergy Asthma Clin Immunol pmid:20525159
Manickam E et al. Suppressive actions of eicosapentaenoic acid on lipid droplet formation in 3T3-L1 adipocytes. 2010 Lipids Health Dis pmid:20525346
Normand-Lauzière F et al. Increased postprandial nonesterified fatty acid appearance and oxidation in type 2 diabetes is not fully established in offspring of diabetic subjects. 2010 PLoS ONE pmid:20532041
Wang J et al. Solid-state interactions of a drug substance and excipients and their impact on tablet dissolution: a thermal-mechanical facilitated process-induced transformation or PIT. 2010 J Pharm Sci pmid:20533436
Foster SP and Johnson CP Feeding and hemolymph trehalose concentration influence sex pheromone production in virgin Heliothis virescens moths. 2010 J. Insect Physiol. pmid:20540946
Asai T and Fujimoto Y Cyclic fatty acyl glycosides in the glandular trichome exudate of Silene gallica. 2010 Phytochemistry pmid:20541780
Brestkina MD et al. [Use of bio-testing on aquatic animals in the assessment of the quality of raw materials in the production of polymeric materials of medical purpose]. 1991 Gig Sanit pmid:2055528
Karande AD et al. In-line quantification of micronized drug and excipients in tablets by near infrared (NIR) spectroscopy: Real time monitoring of tabletting process. 2010 Int J Pharm pmid:20558264
Eftaiha AF et al. Bioadhesive controlled metronidazole release matrix based on chitosan and xanthan gum. 2010 Mar Drugs pmid:20559494
Lin SY et al. Solid-state transformation of different gabapentin polymorphs upon milling and co-milling. 2010 Int J Pharm pmid:20561572
González-Mira E et al. Potential use of nanostructured lipid carriers for topical delivery of flurbiprofen. 2011 J Pharm Sci pmid:20575052
Luan L et al. [Studies on the chemical constituents of extract with water from Forsythia suspensa]. 2010 Zhong Yao Cai pmid:20575415
Keny RV et al. Formulation and evaluation of rizatriptan benzoate mouth disintegrating tablets. 2010 Indian J Pharm Sci pmid:20582194
Rao KS and Srinivas K RP-HPLC Method for the Determination of Losartan Potassium and Ramipril in Combined Dosage Form. 2010 Indian J Pharm Sci pmid:20582199
Bele MH et al. Effect of Flow Aids on Mucoadhesive Properties of Polymeric Discs of Polyoxyethylene and Carbopol 971P. 2010 Indian J Pharm Sci pmid:20582205
Hart CM et al. Supplemental fatty acids alter lipid peroxidation and oxidant injury in endothelial cells. 1991 Am. J. Physiol. pmid:2058691
Teixeira AC et al. Phase behaviour of oleanolic acid, pure and mixed with stearic acid: Interactions and crystallinity. 2010 Chem. Phys. Lipids pmid:20599856
Westerbacka J et al. Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease. 2010 Gastroenterology pmid:20600015
Gilani K et al. Development of respirable nanomicelle carriers for delivery of amphotericin B by jet nebulization. 2011 J Pharm Sci pmid:20602350
Chon B et al. Shell and ligand-dependent blinking of CdSe-based core/shell nanocrystals. 2010 Phys Chem Chem Phys pmid:20607188
Invernizzi G et al. Sustained upregulation of stearoyl-CoA desaturase in bovine mammary tissue with contrasting changes in milk fat synthesis and lipogenic gene networks caused by lipid supplements. 2010 Funct. Integr. Genomics pmid:20607344
Gentile CL et al. Fatty acids regulate CREBh via transcriptional mechanisms that are dependent on proteasome activity and insulin. 2010 Mol. Cell. Biochem. pmid:20607591
Borah BM et al. Surface-modification-directed controlled adsorption of serum albumin onto magnetite nanocuboids synthesized in a gel-diffusion technique. 2010 J Colloid Interface Sci pmid:20621808
Legrand P and Rioux V The complex and important cellular and metabolic functions of saturated fatty acids. 2010 Lipids pmid:20625935
Hodson L et al. Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20628024
Chen CJ et al. Preparation of Monodisperse Iron Oxide Nanoparticles via the Synthesis and Decomposition of Iron Fatty Acid Complexes. 2009 Nanoscale Res Lett pmid:20628451
Saravanakumari P and Mani K Structural characterization of a novel xylolipid biosurfactant from Lactococcus lactis and analysis of antibacterial activity against multi-drug resistant pathogens. 2010 Bioresour. Technol. pmid:20637606
Pöllänen E et al. Power training and postmenopausal hormone therapy affect transcriptional control of specific co-regulated gene clusters in skeletal muscle. 2010 Age (Dordr) pmid:20640546
Pennick G et al. Superior effect of isostearyl isostearate on improvement in stratum corneum water permeability barrier function as examined by the plastic occlusion stress test. 2010 Int J Cosmet Sci pmid:20642769
Kushner J and Moore F Scale-up model describing the impact of lubrication on tablet tensile strength. 2010 Int J Pharm pmid:20667504
Imae R et al. Intracellular phospholipase A1 and acyltransferase, which are involved in Caenorhabditis elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol. 2010 Mol. Biol. Cell pmid:20668164
Walker S et al. Synthesis, processing and solid state excipient interactions of cucurbit[6]uril and its formulation into tablets for oral drug delivery. 2010 Mol. Pharm. pmid:20669974
Wang Q et al. One-Step Synthesis of Monodisperse In-Doped ZnO Nanocrystals. 2010 Nanoscale Res Lett pmid:20672040
Tripathi B et al. Fortification of sorghum (Sorghum vulgare) and pearl millet (Pennisetum glaucum) flour with zinc. 2010 J Trace Elem Med Biol pmid:20685098
Vlachou M et al. Utilization of hydrophilic swellable polymers as carriers for sustained drug delivery from matrices and three layer tablet systems. 2010 Curr Drug Deliv pmid:20695845
Maher AC et al. Women have higher protein content of beta-oxidation enzymes in skeletal muscle than men. 2010 PLoS ONE pmid:20700461
Yoo HJ and HÃ¥kansson K Determination of double bond location in fatty acids by manganese adduction and electron induced dissociation. 2010 Anal. Chem. pmid:20704384
Perrault M et al. An experimental investigation of the effect of the amount of lubricant on tablet properties. 2011 Drug Dev Ind Pharm pmid:20704461
Noguchi Y et al. Ketogenic essential amino acids modulate lipid synthetic pathways and prevent hepatic steatosis in mice. 2010 PLoS ONE pmid:20706589
Tiemeyer S et al. Effect of surface charge distribution on the adsorption orientation of proteins to lipid monolayers. 2010 Langmuir pmid:20707324
Yuan Y et al. A signal-on electrochemical probe-label-free aptasensor using gold-platinum alloy and stearic acid as enhancers. 2010 Biosens Bioelectron pmid:20708400
Horne I et al. Two conserved Z9-octadecanoic acid desaturases in the red flour beetle, Tribolium castaneum. 2010 Gene pmid:20709164
Muro M et al. A conformation and orientation model of the carboxylic group of fatty acids dependent on chain length in a Langmuir monolayer film studied by polarization-modulation infrared reflection absorption spectroscopy. 2010 J Phys Chem B pmid:20718412
Gonzalez-Mira E et al. Design and ocular tolerance of flurbiprofen loaded ultrasound-engineered NLC. 2010 Colloids Surf B Biointerfaces pmid:20719479
Jelvehgari M et al. Formulation, characterization and in vitro evaluation of theophylline-loaded Eudragit RS 100 microspheres prepared by an emulsion-solvent diffusion/evaporation technique. 2011 Nov-Dec Pharm Dev Technol pmid:20722498
Chakraborty S et al. Utilization of adsorption technique in the development of oral delivery system of lipid based nanoparticles. 2010 Colloids Surf B Biointerfaces pmid:20728320
Chen X et al. Plasma metabolomics reveals biomarkers of the atherosclerosis. 2010 J Sep Sci pmid:20730840
Su C et al. A novel assay of cellular stearoyl-CoA desaturase activity of primary rat hepatocytes by HPLC. 2010 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:20732836
Tsai MJ et al. Oral apomorphine delivery from solid lipid nanoparticles with different monostearate emulsifiers: pharmacokinetic and behavioral evaluations. 2011 J Pharm Sci pmid:20740670
Shepherd J et al. Effects of dietary polyunsaturated and saturated fat on the properties of high density lipoproteins and the metabolism of apolipoprotein A-I. 1978 J. Clin. Invest. pmid:207739
Guzmán A and García R Effects of fatty ethers and stearic acid on the gastrointestinal absorption of insulin. 1990 P R Health Sci J pmid:2077554
Bentejac M et al. Metabolic fate of sphingomyelin of high-density lipoprotein in rat plasma. 1990 Lipids pmid:2079870
Moore F et al. Improving the hardness of dry granulated tablets containing sodium lauryl sulfate. 2010 Int J Pharm pmid:20801204