stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Decalcification, Pathologic D003649 1 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


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Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

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Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
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Authors Title Published Journal PubMed Link
pmid:9608395
Jenke D Extraction of stearate salts from plastic materials used in pharmaceutical applications. PDA J Pharm Sci Technol pmid:21502020
Geslin JM et al. [Allergic respiratory disorders and vein sclerosis with lauromacrogol 400]. Therapie pmid:15789831
SWERN D et al. Unsaturated alcohol esters of the 9,10-dihydroxystearic acids; preparation of elaidyl alcohol. 1946 J. Am. Chem. Soc. pmid:20995013
VOLD RD and PHILIPSON JM The behavior of sodium stearate with cetane and water. 1946 J Phys Chem pmid:21010917
NIGHTINGALE G et al. Effect of dihydroxystearic acid on vitamin K synthesis by rats. 1947 Arch Biochem pmid:20291026
GREGORY JN and SPINK JA Lubricating properties of molecular layers of stearic acid and calcium stearate on metal surfaces. 1947 Nature pmid:20291788
WITTCOFF H and MILLER SE Hydroxylated stearic acids; action of Prevost's reagent on oleic and elaidic esters; evidence for configuration of the hydroxy acids. 1947 J. Am. Chem. Soc. pmid:18919716
OULLET C and DUBOIS JT [Not Available]. 1948 Can J Res pmid:18913992
McKAY AF and BADER AR The preparation and properties of the eight diastereoisomers of 9,10,12,13-tetrahydroxystearic acid. 1948 J. Org. Chem. pmid:18917710