| MeSH term | MeSH ID | Detail |
|---|---|---|
| Decalcification, Pathologic | D003649 | 1 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| French SJ et al. | The effects of intestinal infusion of long-chain fatty acids on food intake in humans. | 2000 | Gastroenterology | pmid:11040181 |
| Janicki RS et al. | Comparison of erythromycin ethyl succinate, stearate and estolate treatments of group A streptococcal infections of the upper respiratory tract. | 1975 | Clin Pediatr (Phila) | pmid:1104241 |
| Granot E et al. | Breast-fed and formula-fed infants do not differ in immunocompetent cell cytokine production despite differences in cell membrane fatty acid composition. | 2000 | Am. J. Clin. Nutr. | pmid:11063450 |
| Männistö P et al. | Absorption of erythromycin. A cross-over study in healthy volunteers. | 1975 | Arzneimittelforschung | pmid:1106445 |
| Daubresse JC | [Atherosclerosis and nutrition]. | 2000 | Rev Med Brux | pmid:11068494 |
| Schwarzmann G et al. | Using biotinylated gangliosides to study their distribution and traffic in cells by immunoelectron microscopy. | 2000 | Meth. Enzymol. | pmid:11070901 |
| Podczeck F and Newton JM | Powder and capsule filling properties of lubricated granulated cellulose powder. | 2000 | Eur J Pharm Biopharm | pmid:11072194 |
| Knopp RH et al. | One-year effects of increasingly fat-restricted, carbohydrate-enriched diets on lipoprotein levels in free-living subjects. | 2000 | Proc. Soc. Exp. Biol. Med. | pmid:11082213 |
| Chayabutra C et al. | Rhamnolipid production by Pseudomonas aeruginosa under denitrification: effects of limiting nutrients and carbon substrates. | 2001 | Biotechnol. Bioeng. | pmid:11084590 |
| Hannah VC et al. | Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells. | 2001 | J. Biol. Chem. | pmid:11085986 |
| Mizukoshi Y et al. | Preparation of platinum nanoparticles by sonochemical reduction of the Pt(IV) ions: role of surfactants. | 2001 | Ultrason Sonochem | pmid:11105315 |
| Fitch CD et al. | A role for linoleic acid in erythrocytes infected with Plasmodium berghei. | 2000 | Biochim. Biophys. Acta | pmid:11113630 |
| Williams EE et al. | The curvature and cholesterol content of phospholipid bilayers alter the transbilayer distribution of specific molecular species of phosphatidylethanolamine. | 2000 Jul-Sep | Mol. Membr. Biol. | pmid:11128974 |
| Leese GP et al. | Effects of growth hormone treatment on red cell plasma membrane fatty acid constituents in hypopituitary adults. | 2000 | Scott Med J | pmid:11130294 |
| Wu J et al. | Influence of wet granulation and lubrication on the powder and tableting properties of codried product of microcrystalline cellulose with beta-cyclodextrin. | 2001 | Eur J Pharm Biopharm | pmid:11154905 |
| Smith AM et al. | Phase I/II study of G17-DT, an anti-gastrin immunogen, in advanced colorectal cancer. | 2000 | Clin. Cancer Res. | pmid:11156225 |
| Montell E et al. | DAG accumulation from saturated fatty acids desensitizes insulin stimulation of glucose uptake in muscle cells. | 2001 | Am. J. Physiol. Endocrinol. Metab. | pmid:11158925 |
| Sakuma S et al. | The effects of fatty acyl CoA esters on the formation of prostaglandin and arachidonoyl-CoA formed from arachidonic acid in rabbit kidney medulla microsomes. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11161586 |
| Fukui E et al. | An in vitro investigation of the suitability of press-coated tablets with hydroxypropylmethylcellulose acetate succinate (HPMCAS) and hydrophobic additives in the outer shell for colon targeting. | 2001 | J Control Release | pmid:11166411 |
| Kita K et al. | Characterization of the reversible nature of the reaction catalyzed by sphingolipid ceramide N-deacylase. A novel form of reverse hydrolysis reaction. | 2001 | Eur. J. Biochem. | pmid:11168398 |
| Byrdwell WC et al. | Triacylglycerol analysis of potential margarine base stocks by high-performance liquid chromatography with atmospheric pressure chemical ionization mass spectrometry and flame ionization detection. | 2001 | J. Agric. Food Chem. | pmid:11170612 |
| Kaushik N and Vir S | Variations in fatty acid composition of neem seeds collected from the Rajasthan state of India. | 2000 | Biochem. Soc. Trans. | pmid:11171243 |
| Parveez GK et al. | Transgenic oil palm: production and projection. | 2000 | Biochem. Soc. Trans. | pmid:11171275 |
| Habán P et al. | Oleic acid serum phospholipid content is linked with the serum total- and LDL-cholesterol in elderly subjects. | 2000 Nov-Dec | Med. Sci. Monit. | pmid:11208461 |
| De Vriese SR et al. | The composition of saturated fatty acids in plasma phospholipids changes in a way to counteract changes in the mean melting point during pregnancy. | 2001 | Lipids | pmid:11214724 |
| Fatibello-Filho O and Vieira IC | Construction and analytical application of a biosensor based on stearic acid-graphite powder modified with sweet potato tissue in organic solvents. | 2000 | Fresenius J Anal Chem | pmid:11227501 |
| Liang P et al. | [Chemical constituents of Pericampylus glaucus (Lam.) Merr]. | 1998 | Zhongguo Zhong Yao Za Zhi | pmid:11243154 |
| Thosar SS et al. | A comparison of reflectance and transmittance near-infrared spectroscopic techniques in determining drug content in intact tablets. | 2001 | Pharm Dev Technol | pmid:11247272 |
| Höltje M et al. | Molecular dynamics simulations of stratum corneum lipid models: fatty acids and cholesterol. | 2001 | Biochim. Biophys. Acta | pmid:11248214 |
| Sabir A et al. | Formulation and process optimization to eliminate picking from market image tablets. | 2001 | Int J Pharm | pmid:11250098 |
| Nishioka Y and Yoshino H | Lymphatic targeting with nanoparticulate system. | 2001 | Adv. Drug Deliv. Rev. | pmid:11251245 |
| Hatta I et al. | X-ray diffraction study on ordered, disordered and reconstituted intercellular lipid lamellar structure in stratum corneum. | 2001 | Biophys. Chem. | pmid:11254216 |
| Alves MM et al. | Effects of lipids and oleic acid on biomass development in anaerobic fixed-bed reactors. Part II: Oleic acid toxicity and biodegradability. | 2001 | Water Res. | pmid:11257881 |
| Harwood JL and James AT | Metabolism of trans-3-hexadecenoic acid in broad bean. | 1975 | Eur. J. Biochem. | pmid:1126340 |
| Fukui E et al. | Effect of magnesium stearate or calcium stearate as additives on dissolution profiles of diltiazem hydrochloride from press-coated tablets with hydroxypropylmethylcellulose acetate succinate in the outer shell. | 2001 | Int J Pharm | pmid:11274815 |
| Liu Q et al. | Genetic modification of cotton seed oil using inverted-repeat gene-silencing techniques. | 2000 | Biochem. Soc. Trans. | pmid:11288706 |
| van den Bergh BA et al. | Elasticity of vesicles assessed by electron spin resonance, electron microscopy and extrusion measurements. | 2001 | Int J Pharm | pmid:11292538 |
| Kelly FD et al. | A stearic acid-rich diet improves thrombogenic and atherogenic risk factor profiles in healthy males. | 2001 | Eur J Clin Nutr | pmid:11305631 |
| Oviedo JM et al. | Pulmonary surfactant protein SP-B is significantly more immunoreactive in anionic than in zwitterionic bilayers. | 2001 | FEBS Lett. | pmid:11311247 |
| Pacia SV et al. | Biogenic amines in the human neocortex in patients with neocortical and mesial temporal lobe epilepsy: identification with in situ microvoltammetry. | 2001 | Brain Res. | pmid:11311871 |
| Ulmann L et al. | Brain and hippocampus fatty acid composition in phospholipid classes of aged-relative cognitive deficit rats. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11334555 |
| Korkishko YN et al. | Characterization of alpha-phase soft proton-exchanged LiNbO3 optical waveguides. | 2001 | J Opt Soc Am A Opt Image Sci Vis | pmid:11336221 |
| Andrès C et al. | On the difficulty of assessing the specific surface area of magnesium stearate. | 2001 | Int J Pharm | pmid:11337159 |
| Ves-Losada A et al. | Incorporation and distribution of saturated and unsaturated fatty acids into nuclear lipids of hepatic cells. | 2001 | Lipids | pmid:11337983 |
| Dean DD et al. | Effect of polymer molecular weight and addition of calcium stearate on response of MG63 osteoblast-like cells to UHMWPE particles. | 2001 | J. Orthop. Res. | pmid:11347688 |
| Hong CY | Discovery of gemifloxacin (Factive, LB20304a): a quinolone of a new generation. | 2001 Jan-Feb | Farmaco | pmid:11347965 |
| Ferreira JA et al. | Hydrophobic interactions between spin-label 5-SASL and humic acid as revealed by ESR spectroscopy. | 2001 | Environ. Sci. Technol. | pmid:11349289 |
| DePeters EJ et al. | Fatty acid and triglyceride composition of milk fat from lactating Holstein cows in response to supplemental canola oil. | 2001 | J. Dairy Sci. | pmid:11352169 |
| Ghanouni P et al. | Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11353823 |
| Waddington E et al. | Identification and quantitation of unique fatty acid oxidation products in human atherosclerotic plaque using high-performance liquid chromatography. | 2001 | Anal. Biochem. | pmid:11355856 |
| Clouet P et al. | Mitochondrial respiration on rumenic and linoleic acids. | 2001 | Biochem. Soc. Trans. | pmid:11356175 |
| Yu HY et al. | Saturated non-esterified fatty acids stimulate de novo diacylglycerol synthesis and protein kinase c activity in cultured aortic smooth muscle cells. | 2001 | Diabetologia | pmid:11380080 |
| Kuksis A et al. | Distribution of newly formed fatty acids among glycerolipids of isolated perfused rat liver. | 1975 | Can. J. Biochem. | pmid:1139394 |
| Kuksis A et al. | Distribution of newly formed palmitate and stearate among molecular species of choline and ethanolamine phosphatides. | 1975 | Can. J. Biochem. | pmid:1139395 |
| Parkes JG and Thompson W | Phosphatidylethanolamine in liver mitochondria and endoplasmic reticulum: molecular species distribution and turnover. | 1975 | Can. J. Biochem. | pmid:1139407 |
| Bolhuis GK et al. | DC calcium lactate, a new filler-binder for direct compaction of tablets. | 2001 | Int J Pharm | pmid:11397569 |
| Chen H et al. | Effect of cholesterol on miscibility and phase behavior in binary mixtures with synthetic ceramide 2 and octadecanoic acid. Infrared studies. | 2001 | Biochim. Biophys. Acta | pmid:11406112 |
| Kamm W et al. | Analysis of steryl esters in cocoa butter by on-line liquid chromatography-gas chromatography. | 2001 | J Chromatogr A | pmid:11407581 |
| Hashimoto F et al. | Accumulation of medium chain acyl-CoAs during beta-oxidation of long chain fatty acid by isolated peroxisomes from rat liver. | 2001 | Biol. Pharm. Bull. | pmid:11411544 |
| Zhang L et al. | Isolation and characterization of the human stearoyl-CoA desaturase gene promoter: requirement of a conserved CCAAT cis-element. | 2001 | Biochem. J. | pmid:11415448 |
| Morita YS and Englund PT | Fatty acid remodeling of glycosyl phosphatidylinositol anchors in Trypanosoma brucei: incorporation of fatty acids other than myristate. | 2001 | Mol. Biochem. Parasitol. | pmid:11420102 |
| Liang X et al. | Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction. | 2001 | J. Biol. Chem. | pmid:11423543 |
| Kim JY et al. | Lipid and fatty acid analysis of fresh and frozen-thawed immature and in vitro matured bovine oocytes. | 2001 | Reproduction | pmid:11425337 |
| Radwan SS et al. | Effects of lipids on n-alkane attenuation in media supporting oil-utilizing microorganisms from the oily Arabian Gulf coasts. | 2001 | FEMS Microbiol. Lett. | pmid:11430415 |
| Hilpert B et al. | Isolation and characterization of signal transduction mutants of Arabidopsis thaliana that constitutively activate the octadecanoid pathway and form necrotic microlesions. | 2001 | Plant J. | pmid:11439130 |
| Thompson GE and Darling KF | The hepatic uptake of individual free fatty acids in sheep during noradrenaline infusion. | 1975 | Res. Vet. Sci. | pmid:1144925 |
| Mu YM et al. | Saturated FFAs, palmitic acid and stearic acid, induce apoptosis in human granulosa cells. | 2001 | Endocrinology | pmid:11459807 |
| Lalman JA and Bagley DM | Anaerobic degradation and methanogenic inhibitory effects of oleic and stearic acids. | 2001 | Water Res. | pmid:11471698 |
| Gupta SV and Khosla P | Palmitic and stearic acids similarly affect plasma lipoprotein metabolism in cynomolgus monkeys fed diets with adequate levels of linoleic acid. | 2001 | J. Nutr. | pmid:11481404 |
| Choo CY et al. | The cytotoxicity and chemical constituents of the hexane fraction of Typhonium flagelliforme (Araceace). | 2001 | J Ethnopharmacol | pmid:11483390 |
| Wu P et al. | Atemoyacin E, a bis-tetrahydrofuran annonaceous acetogenin from Annona atemoya seeds. | 2001 | J Asian Nat Prod Res | pmid:11491392 |
| Hunter KA et al. | Effect of diets rich in oleic acid, stearic acid and linoleic acid on postprandial haemostatic factors in young healthy men. | 2001 | Br. J. Nutr. | pmid:11502234 |
| Zaghloul AA et al. | Response surface methodology to obtain naproxen controlled release tablets from its microspheres with Eudragit L100-55. | J Microencapsul | pmid:11508770 | |
| Takamoto DY et al. | Stable ordering in Langmuir-Blodgett films. | 2001 | Science | pmid:11509723 |
| York P | Application of powder failure testing equipment in assessing effect on glidants on flowability of cohesive pharmaceutical powders. | 1975 | J Pharm Sci | pmid:1151687 |
| Pierri EG et al. | Determination of oxamniquine in capsules by HPLC. | 2001 | J Pharm Biomed Anal | pmid:11516919 |
| Ebba F et al. | Stress relaxation studies of granules as a function of different lubricants. | 2001 | Eur J Pharm Biopharm | pmid:11522488 |
| Boros LG and Williams RD | Isofenphos induced metabolic changes in K562 myeloid blast cells. | 2001 | Leuk. Res. | pmid:11532522 |
| Russell NJ and Harwood JL | Changes in the acyl lipid composition of photosynthetic bacteria grown under photosynthetic and non-photosynthetic conditions. | 1979 | Biochem. J. | pmid:115463 |
| Fomuso LB and Akoh CC | Enzymatic modification of high-laurate canola to produce margarine fat. | 2001 | J. Agric. Food Chem. | pmid:11559158 |
| Weaire PJ and Kekwick RG | The fractionation of the fatty acid synthetase activities of avocado mesocarp plastids. | 1975 | Biochem. J. | pmid:1156381 |
| Moon YA et al. | Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins. | 2001 | J. Biol. Chem. | pmid:11567032 |
| Shen Z et al. | Fatty acid composition of lysophosphatidic acid and lysophosphatidylinositol in plasma from patients with ovarian cancer and other gynecological diseases. | 2001 | Gynecol. Oncol. | pmid:11585410 |
| Nakanishi M et al. | Characterisation of myogenic cell membrane: II. Dynamic changes in membrane lipids during the differentiation of mouse C2 myoblast cells. | 2001 | Cell Biol. Int. | pmid:11589611 |
| Bézaire V et al. | Effects of fasting on muscle mitochondrial energetics and fatty acid metabolism in Ucp3(-/-) and wild-type mice. | 2001 | Am. J. Physiol. Endocrinol. Metab. | pmid:11595653 |
| Haastrup A et al. | Lipids stimulate the production of 6-keto-prostaglandin f(1alpha) in human dorsal hand veins. | 2001 | Hypertension | pmid:11641299 |
| Baines DL et al. | Fatty acid modulation and sequence identity of fetal guinea pig alveolar type II cell amiloride-sensitive Na+ channel. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11676504 |
| Voinovich D et al. | Melt pelletization in high shear mixer using a hydrophobic melt binder: influence of some apparatus and process variables. | 2001 | Eur J Pharm Biopharm | pmid:11677073 |
| Rahamatalla AB et al. | Changes in fatty acids composition during seed growth and physicochemical characteristics of oil extracted from four safflower cultivars. | 2001 | Plant Foods Hum Nutr | pmid:11678443 |
| Maynar M et al. | Menopause-induced changes in lipid fractions and total fatty acids in plasma. | 2001 | Endocr. Res. | pmid:11678583 |
| Stehlin C et al. | X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation. | 2001 | EMBO J. | pmid:11689423 |
| Raila J et al. | Plasma transport and tissue distribution of beta-carotene, vitamin A and retinol-binding protein in domestic cats. | 2001 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:11691620 |
| Finley JW and Davis CD | Manganese absorption and retention in rats is affected by the type of dietary fat. | 2001 | Biol Trace Elem Res | pmid:11697763 |
| Khabbaz F and Albertsson AC | Great advantages in using a natural rubber instead of a synthetic SBR in a pro-oxidant system for degradable LDPE. | 2000 | Biomacromolecules | pmid:11710197 |
| Mironova GD et al. | Palmitic and stearic acids bind Ca2+ with high affinity and form nonspecific channels in black-lipid membranes. Possible relation to Ca2+-activated mitochondrial pores. | 2001 | J. Bioenerg. Biomembr. | pmid:11710807 |
| Futaki S et al. | Stearylated arginine-rich peptides: a new class of transfection systems. | 2001 Nov-Dec | Bioconjug. Chem. | pmid:11716693 |
| Garzón Mde L and Villafuerte L | Compactibility of mixtures of calcium carbonate and microcrystalline cellulose. | 2002 | Int J Pharm | pmid:11719011 |
| Carballeira NM et al. | Identification and total synthesis of novel fatty acids from the Siphonarid limpet Siphonaria denticulata. | 2001 | J. Nat. Prod. | pmid:11720525 |
| Chen DB et al. | In vitro and in vivo study of two types of long-circulating solid lipid nanoparticles containing paclitaxel. | 2001 | Chem. Pharm. Bull. | pmid:11724235 |
| Glew RH et al. | Fatty acid composition of the milk lipids of Nepalese women: correlation between fatty acid composition of serum phospholipids and melting point. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728165 |