MeSH term | MeSH ID | Detail |
---|---|---|
Decalcification, Pathologic | D003649 | 1 associated lipids |
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Warhurst DC et al. | The chemotherapy of rodent malaria, XXIV. The blood schizontocidal action of erythromycin upon Plasmodium berghei. | 1976 | Ann Trop Med Parasitol | pmid:788656 |
Percival L et al. | A case study of dermatitis based on a collaborative approach between occupational physicians and industrial hygienists. | 1995 | Am Ind Hyg Assoc J | pmid:7856518 |
Catalá A et al. | Interaction of rat liver microsomes containing saturated or unsaturated fatty acids with fatty acid binding protein: peroxidation effect. | 1994 | Mol. Cell. Biochem. | pmid:7845387 |
de Alaniz MJ and Marra CA | Role of delta 9 desaturase activity in the maintenance of high levels of monoenoic fatty acids in hepatoma cultured cells. | 1994 | Mol. Cell. Biochem. | pmid:7845382 |
Kaewvichit S and Tucker IG | The release of macromolecules from fatty acid matrices: complete factorial study of factors affecting release. | 1994 | J. Pharm. Pharmacol. | pmid:7837038 |
Shoji Y et al. | Effect of topical preparation of mycophenolic acid on experimental allergic contact dermatitis of guinea-pigs induced by dinitrofluorobenzene. | 1994 | J. Pharm. Pharmacol. | pmid:7815276 |
Aggarwal M et al. | The effect of Cd2+ on lipid components of sunflower (Helianthus annuus L.) seeds. | 1995 | Plant Foods Hum Nutr | pmid:7792263 |
Lai HC et al. | Alteration of plasma lipids in the rat by fractionation of modified milk fat (butterfat). | 1995 | J. Dairy Sci. | pmid:7790571 |
Fujimoto Y et al. | Effects of fatty acyl coenzyme A esters on lipoxygenase and cyclooxygenase metabolism of arachidonic acid in rabbit platelets. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7784474 |
Lai HC and Ney DM | Corn oil, palm oil and butterfat fractions affect postprandial lipemia and lipoprotein lipase in meal-fed rats. | 1995 | J. Nutr. | pmid:7782908 |