stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Decalcification, Pathologic D003649 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


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Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Salem N and Niebylski CD The nervous system has an absolute molecular species requirement for proper function. 1995 Jan-Mar Mol. Membr. Biol. pmid:7767372
Thompson W and MacDonald G Cytidine diphosphate diglyceride of bovine brain. Positional distribution of fatty acids and analysis of major molecular species. 1976 Eur. J. Biochem. pmid:776622
Morrow MR et al. Glycosphingolipid acyl chain order profiles: substituent effects. 1995 Biochim. Biophys. Acta pmid:7756331
Blechert S et al. The octadecanoic pathway: signal molecules for the regulation of secondary pathways. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7753776
Pandey M et al. Erythrocyte membrane fatty acid profile in patients with primary carcinoma of the gallbladder. 1995 J Surg Oncol pmid:7745974
Yu S et al. Plasma cholesterol-predictive equations demonstrate that stearic acid is neutral and monounsaturated fatty acids are hypocholesterolemic. 1995 Am. J. Clin. Nutr. pmid:7733039
Dougherty RM et al. Effects of diets containing high or low amounts of stearic acid on plasma lipoprotein fractions and fecal fatty acid excretion of men. 1995 Am. J. Clin. Nutr. pmid:7733038
Robert S et al. Fatty acid acylation of RNase A using reversed micelles as microreactors. 1993 Biochem. Biophys. Res. Commun. pmid:7692851
Keita Y et al. Effect of free fatty acids on the binding kinetics at the benzodiazepine binding site of glycated human serum albumin. 1993 Int J Clin Pharmacol Ther Toxicol pmid:7690351
Fujimoto T et al. P-selectin is acylated with palmitic acid and stearic acid at cysteine 766 through a thioester linkage. 1993 J. Biol. Chem. pmid:7684381