stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Decalcification, Pathologic D003649 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


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What lipids are associated with stearic acid?

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
MUNZEL K and AMMANN R [Washable oil-water ointments. V. Complex-emulsified ointments; differences between stearate- and complex-emulsified ointments]. 1954 Pharm Acta Helv pmid:13194353
SCRIBANTE P and FAVARGER P [Studies on digestibility of stearic acid and its glyceric esters in rat]. 1954 Helv Physiol Pharmacol Acta pmid:13201008
MUNZEL K and AMMANN R [On washable fat-in-water ointments. IV. Stearate ointments]. 1954 Pharm Acta Helv pmid:13166515
DUNCOMBE WG and GLASCOCK RF The contribution of dietary stearic acid to milk fat. 1954 Biochem. J. pmid:13172205
BERGSTROM S et al. Intestinal absorption and metabolism of 2:2-dimethylstearic acid in the rat. 1954 Biochem. J. pmid:13230010
GLASCOCK RF and REINIUS LR Location of tritium in stearic acid produced by catalytic tritiation of elaidic acid. 1954 Biochem. J. pmid:13230049
SHAFER JK and SMITH CA Treatment of early infectious syphilis with N,N'-dibenzylethylenediamine dipenicillin G; a second report. 1954 Bull. World Health Organ. pmid:13182589
MUNZEL K and AMMANN R [Contributions on the character of water-soluble fatty ointments. X. Quasiviscosity determination of stearate ointments]. 1955 Pharm Acta Helv pmid:13289260
SULMAN FG A note on the resorption and excretion of riboflavine from aluminium monostearate suspensions in the rat. 1955 J. Pharm. Pharmacol. pmid:14392601
POLYOXYETHYLENE stearates in food. 1955 Nutr. Rev. pmid:14394517