| MeSH term | MeSH ID | Detail |
|---|---|---|
| Decalcification, Pathologic | D003649 | 1 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Linden DJ and Routtenberg A | cis-Fatty acids, which activate protein kinase C, attenuate Na+ and Ca2+ currents in mouse neuroblastoma cells. | 1989 | J. Physiol. (Lond.) | pmid:2559978 |
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| Beck JC et al. | Growth of epithelium from a preneoplastic mammary outgrowth in response to mammary adipose tissue. | 1989 | In Vitro Cell. Dev. Biol. | pmid:2732196 |
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| Jones RE and Plymate SR | Evidence for the regulation of fatty acid utilization in human sperm by docosahexaenoic acid. | 1988 | Biol. Reprod. | pmid:2905175 |
| Van Rafelghem MJ and Andersen ME | The effects of perfluorodecanoic acid on hepatic stearoyl-coenzyme A desaturase and mixed function oxidase activities in rats. | 1988 | Fundam Appl Toxicol | pmid:2906022 |
| Baichwal AR and Augsburger LL | Variations in the friction coefficients of tablet lubricants and relationship to their physicochemical properties. | 1988 | J. Pharm. Pharmacol. | pmid:2907013 |
| Longmuir KJ and Rossi ME | Fatty acid chain-shortening activity in the pulmonary type II cell. | 1988 | Biochim. Biophys. Acta | pmid:3289622 |
| Kaya K and Kusumi T | Isolation and structural characterization of a diacyltaurolipid in cells of Tetrahymena mimbres. | 1988 | Biochim. Biophys. Acta | pmid:3132980 |
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| Bach R et al. | Human tissue factor contains thioester-linked palmitate and stearate on the cytoplasmic half-cystine. | 1988 | Biochemistry | pmid:3166978 |
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| Yeh YY | Long chain fatty acid deficits in brain myelin sphingolipids of undernourished rat pups. | 1988 | Lipids | pmid:3226227 |
| Broderick PA | Distinguishing in vitro electrochemical signatures for norepinephrine and dopamine. | 1988 | Neurosci. Lett. | pmid:3226613 |
| Ubels JL et al. | Vitamin A is stored as fatty acyl esters of retinol in the lacrimal gland. | 1988 | Curr. Eye Res. | pmid:3229120 |
| McNulty CA et al. | Inhibitory antimicrobial concentrations against Campylobacter pylori in gastric mucosa. | 1988 | J. Antimicrob. Chemother. | pmid:3209531 |
| Tan S et al. | Gas chromatographic determination of calcium stearate in polyethylene food packaging sheets. | 1988 | J. Chromatogr. | pmid:3209663 |
| Sparace SA et al. | A preliminary analysis of Fatty Acid synthesis in pea roots. | 1988 | Plant Physiol. | pmid:16666088 |
| Horváth LI et al. | Exchange rates at the lipid-protein interface of myelin proteolipid protein studied by spin-label electron spin resonance. | 1988 | Biochemistry | pmid:2450570 |
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