stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Decalcification, Pathologic D003649 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Vicentino C et al. Long-chain fatty acid uptake and oxidation in the perfused liver of Walker-256 tumour-bearing rats. 2002 Liver pmid:12296968
Lee J Intrinsic adhesion properties of poly(vinyl pyrrolidone) to pharmaceutical materials: humidity effect. 2005 Macromol Biosci pmid:16245267
Lacaze C et al. The initial pharmaceutical development of an artesunate/amodiaquine oral formulation for the treatment of malaria: a public-private partnership. 2011 Malar. J. pmid:21605361
NIELSEN K and SCHMIDT H [Should the standard treatment of gonorrhea be changed? Effects of the treatment of gonorrhea in 1960 in ambulant and hospitalized patients]. 1962 Manedsskr Prakt Laegegern pmid:13938514
El Hadrami A et al. Chitosan in plant protection. 2010 Mar Drugs pmid:20479963
Eftaiha AF et al. Bioadhesive controlled metronidazole release matrix based on chitosan and xanthan gum. 2010 Mar Drugs pmid:20559494
Phaechamud T et al. Chitosan-aluminum monostearate composite sponge dressing containing asiaticoside for wound healing and angiogenesis promotion in chronic wound. 2015 Mater Sci Eng C Mater Biol Appl pmid:25746264
Sagiri SS et al. Stearic acid based oleogels: a study on the molecular, thermal and mechanical properties. 2015 Mater Sci Eng C Mater Biol Appl pmid:25579972
Yodkhum K and Phaechamud T Hydrophobic chitosan sponges modified by aluminum monostearate and dehydrothermal treatment as sustained drug delivery system. 2014 Mater Sci Eng C Mater Biol Appl pmid:25063173
Sguizzato M et al. Solid lipid nanoparticles for the delivery of 1,3,5-triaza-7-phosphaadamantane (PTA) platinum (II) carboxylates. 2017 Mater Sci Eng C Mater Biol Appl pmid:28254304
Eltayeb M et al. Electrosprayed nanoparticle delivery system for controlled release. 2016 Mater Sci Eng C Mater Biol Appl pmid:27207047
Ma F et al. Improvement of β-TCP/PLLA biodegradable material by surface modification with stearic acid. 2016 Mater Sci Eng C Mater Biol Appl pmid:26952440
Hong J et al. Effects of genetic variants for the swine FABP3, HMGA1, MC4R, IGF2, and FABP4 genes on fatty acid composition. 2015 Meat Sci. pmid:26172243
Whitney TR et al. Redberry juniper as a roughage source in lamb feedlot rations: wool and carcass characteristics, meat fatty acid profiles, and sensory panel traits. 2011 Meat Sci. pmid:21570776
Kerth CR et al. Consumer sensory evaluation, fatty acid composition, and shelf-life of ground beef with subcutaneous fat trimmings from different carcass locations. 2015 Meat Sci. pmid:25688688
Zamora-Rojas E et al. Prediction of fatty acids content in pig adipose tissue by near infrared spectroscopy: at-line versus in-situ analysis. 2013 Meat Sci. pmid:23793086
Ospina-E JC et al. Development of combinations of chemically modified vegetable oils as pork backfat substitutes in sausages formulation. 2010 Meat Sci. pmid:20374815
Lorenzo JM Changes on physico-chemical, textural, lipolysis and volatile compounds during the manufacture of dry-cured foal "cecina". 2014 Meat Sci. pmid:23916960
Eiras CE et al. Glycerine levels in the diets of crossbred bulls finished in feedlot: carcass characteristics and meat quality. 2014 Meat Sci. pmid:24211551
Song S et al. Identification of pork flavour precursors from enzyme-treated lard using Maillard model system assessed by GC-MS and partial least squares regression. 2017 Meat Sci. pmid:27792915
Ercoli N [Clinical and experimental study on an anti-inflammatory preparation of topical use. The 10-undecentil-l-ll pseudothiourea (AHR-1911)]. 1975 Med Cutan Ibero Lat Am pmid:1241792
Loi F and Amati R [Lead-stearate exposure in a plastic factory in the province of Siena (author's transl)]. 1981 Sep-Oct Med Lav pmid:7322018
Sargent JR et al. Nervonic acid and demyelinating disease. 1994 Med. Hypotheses pmid:8072429
Ryan DC et al. Estolate and stearate forms of erythromycin in the treatment of acute beta haemolytic streptococcal pharyngitis. 1973 Med. J. Aust. pmid:4568626
McLeay A and Cooke P Estolate and stearate forms of erythromycin in beta-haemolytic streptococcal pharyngitis. 1973 Med. J. Aust. pmid:4694278
Triggs EJ and Ashley JJ Oral administration of erythromycin stearate: effect of dosage form on plasma levels. 1978 Med. J. Aust. pmid:713930
McLeay AC and Beveridge J Clinical trial of erythromycin stearate suspension. 1971 Med. J. Aust. pmid:4929585
Bell SM A comparison of absorption after oral administration of erythromycin estolate and erythromycin stearate. 1971 Med. J. Aust. pmid:5134726
Smith DD Clinical trial of erythromycin stearate suspension. 1971 Med. J. Aust. pmid:5577264
Eitel K et al. [Apoptosis induced by free fatty acids]. 2003 Med. Klin. (Munich) pmid:12721668
Cvetković Z et al. Distribution of plasma fatty acids is associated with response to chemotherapy in non-Hodgkin's lymphoma patients. 2013 Med. Oncol. pmid:24085546
Habán P et al. Oleic acid serum phospholipid content is linked with the serum total- and LDL-cholesterol in elderly subjects. 2000 Nov-Dec Med. Sci. Monit. pmid:11208461
Savickas A and Bernatoniene J Optimization of "Askoeziuofito" tablets. 2005 Medicina (Kaunas) pmid:15827390
DAMMANN F [Antiphlogistic percutaneous therapy with choline stearate (chomelan)]. 1955 Medizinische pmid:14355526
Khomutov GB et al. Interaction of copper ions with stearic acid Langmuir monolayers and formation of cluster structures in monolayers and Langmuir-Blodgett films. 1997 Membr Cell Biol pmid:9231365
Derr J et al. The role of fatty acid saturation on plasma lipids, lipoproteins, and apolipoproteins: II. The plasma total and low-density lipoprotein cholesterol response of individual fatty acids. 1993 Metab. Clin. Exp. pmid:8446040
Mustad VA et al. Comparison of the effects of diets rich in stearic acid versus myristic acid and lauric acid on platelet fatty acids and excretion of thromboxane A2 and PGI2 metabolites in healthy young men. 1993 Metab. Clin. Exp. pmid:8487669
KAUNITZ H et al. Studies of the generalized Shwartzman reaction produced by diet. IV. Ethyl ester fractions of cod liver oil and dihydroxystearic acid. 1963 Metab. Clin. Exp. pmid:14031428
Schwab US et al. Different effects of palmitic and stearic acid-enriched diets on serum lipids and lipoproteins and plasma cholesteryl ester transfer protein activity in healthy young women. 1996 Metab. Clin. Exp. pmid:8596480
Even P et al. Postprandial effects of a lipid-rich meal in the rat are modulated by the degree of unsaturation of 18C fatty acids. 2010 Metab. Clin. Exp. pmid:19775712
Hennig B et al. Fatty acid-mediated activation of vascular endothelial cells. 2000 Metab. Clin. Exp. pmid:10954018
Hughes TA et al. Comparative lipoprotein metabolism of myristate, palmitate, and stearate in normolipidemic men. 1996 Metab. Clin. Exp. pmid:8781298
Sauvant P et al. Amounts and types of fatty acids in meals affect the pattern of retinoids secreted in human chylomicrons after a high-dose preformed vitamin A intake. 2003 Metab. Clin. Exp. pmid:12701068
Mai K et al. Rosiglitazone increases fatty acid Δ9-desaturation and decreases elongase activity index in human skeletal muscle in vivo. 2012 Metab. Clin. Exp. pmid:21741058
Haas MJ et al. Induction of the apolipoprotein AI promoter by Sp1 is repressed by saturated fatty acids. 2004 Metab. Clin. Exp. pmid:15375792
Hong J et al. The short-term effect of fatty acids on glucagon secretion is influenced by their chain length, spatial configuration, and degree of unsaturation: studies in vitro. 2005 Metab. Clin. Exp. pmid:16154432
Keys A et al. Serum cholesterol response to changes in the diet: IV. Particular saturated fatty acids in the diet. 1965 Metab. Clin. Exp. pmid:25286466
Imai A and Gershengorn MC Measurement of lipid turnover in response to thyrotropin-releasing hormone. 1987 Meth. Enzymol. pmid:3037241
Schwarzmann G et al. Using biotinylated gangliosides to study their distribution and traffic in cells by immunoelectron microscopy. 2000 Meth. Enzymol. pmid:11070901
Bizzozero OA Chemical analysis of acylation sites and species. 1995 Meth. Enzymol. pmid:7651165