| MeSH term | MeSH ID | Detail |
|---|---|---|
| Decalcification, Pathologic | D003649 | 1 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Park JH et al. | Development of DH-I-180-3 loaded lipid nanoparticle for photodynamic therapy. | 2015 | Int J Pharm | pmid:26149935 |
| de Paiva EJ et al. | Influence of two different alcohols in the esterification of fatty acids over layered zinc stearate/palmitate. | 2015 | Bioresour. Technol. | pmid:26143001 |
| Ricci M et al. | Growth and Dissolution of Calcite in the Presence of Adsorbed Stearic Acid. | 2015 | Langmuir | pmid:26087312 |
| Santos IC et al. | Paired-ion electrospray ionization--triple quadrupole tandem mass spectrometry for quantification of anionic surfactants in waters. | 2015 | Talanta | pmid:26078166 |
| Rizzuti B et al. | Fatty acid binding into the highest affinity site of human serum albumin observed in molecular dynamics simulation. | 2015 | Arch. Biochem. Biophys. | pmid:26048999 |
| Foraita S et al. | Impact of the oxygen defects and the hydrogen concentration on the surface of tetragonal and monoclinic ZrO2 on the reduction rates of stearic acid on Ni/ZrO2. | 2015 | Chemistry | pmid:25504844 |
| Yan S et al. | Autoxidated linolenic acid inhibits aflatoxin biosynthesis in Aspergillus flavus via oxylipin species. | 2015 | Fungal Genet. Biol. | pmid:25498164 |
| Yang Y et al. | Ligand-directed stearic acid grafted chitosan micelles to increase therapeutic efficacy in hepatic cancer. | 2015 | Mol. Pharm. | pmid:25495890 |
| Yi HX et al. | Effect of anionic PEGylated polypeptide on gene transfection mediated by glycolipid conjugate micelles. | 2015 | Mol. Pharm. | pmid:25490413 |
| Leonardi A et al. | Cationic solid lipid nanoparticles enhance ocular hypotensive effect of melatonin in rabbit. | 2015 | Int J Pharm | pmid:25448580 |
| Momoh MA et al. | Influence of magnesium stearate on the physicochemical and pharmacodynamic characteristics of insulin-loaded Eudragit entrapped mucoadhesive microspheres. | 2015 | Drug Deliv | pmid:24670092 |
| Doignon F et al. | Requirement of Phosphoinositides Containing Stearic Acid To Control Cell Polarity. | 2015 | Mol. Cell. Biol. | pmid:26711260 |
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| Maphalla TG and Emmambux MN | Functionality of maize, wheat, teff and cassava starches with stearic acid and xanthan gum. | 2016 | Carbohydr Polym | pmid:26572436 |
| Du J and Li L | Which one performs better for targeted lung cancer combination therapy: pre- or post-bombesin-decorated nanostructured lipid carriers? | 2016 | Drug Deliv | pmid:26455787 |
| Kumar Gaur P et al. | Nanovesicles of nitrendipine with lipid complex for transdermal delivery: pharmacokinetic and pharmacodynamic studies. | 2016 | Artif Cells Nanomed Biotechnol | pmid:26375758 |
| Li X et al. | Preparation of co-spray dried cushioning agent containing stearic acid for protecting pellet coatings when compressed. | 2016 | Drug Dev Ind Pharm | pmid:26289006 |
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| Yan G et al. | Preparation and evaluation of liver-targeting micelles loaded with oxaliplatin. | 2016 | Artif Cells Nanomed Biotechnol | pmid:25287740 |
| Pradhan M et al. | Influence of selected variables on fabrication of Triamcinolone acetonide loaded solid lipid nanoparticles for topical treatment of dermal disorders. | 2016 | Artif Cells Nanomed Biotechnol | pmid:25229831 |
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| Yin L et al. | Benzyl butyl phthalate promotes adipogenesis in 3T3-L1 preadipocytes: A High Content Cellomics and metabolomic analysis. | 2016 | Toxicol In Vitro | pmid:26820058 |
| Guan Q et al. | Docetaxel-Loaded Self-Assembly Stearic Acid-Modified Bletilla striata Polysaccharide Micelles and Their Anticancer Effect: Preparation, Characterization, Cellular Uptake and In Vitro Evaluation. | 2016 | Molecules | pmid:27918445 |
| Shur J et al. | From single excipients to dual excipient platforms in dry powder inhaler products. | 2016 | Int J Pharm | pmid:27262269 |
| Li T et al. | Defense priming by non-jasmonate producing fatty acids in maize (Zea mays). | 2016 | Plant Signal Behav | pmid:27763804 |
| Kanasaki Y et al. | Application of Quartz Crystal Microbalance as a Tool for Detergency Evaluation of Fatty Acid Contamination in Aqueous Systems. | 2016 | J Oleo Sci | pmid:27725481 |
| Simon C et al. | Screening of endocrine activity of compounds migrating from plastic baby bottles using a multi-receptor panel of in vitro bioassays. | 2016 | Toxicol In Vitro | pmid:27633901 |
| Shah RM et al. | Microwave-assisted formulation of solid lipid nanoparticles loaded with non-steroidal anti-inflammatory drugs. | 2016 | Int J Pharm | pmid:27789371 |
| Abreu P et al. | Contractile function recovery in severely injured gastrocnemius muscle of rats treated with either oleic or linoleic acid. | 2016 | Exp. Physiol. | pmid:27579497 |
| Garba L et al. | Heterologous Expression of PA8FAD9 and Functional Characterization of a Δ9-Fatty Acid Desaturase from a Cold-Tolerant Pseudomonas sp. A8. | 2016 | Mol. Biotechnol. | pmid:27629791 |
| Yang D et al. | Delivery of siRNA Using Cationic Liposomes Incorporating Stearic Acid-modified Octa-Arginine. | 2016 | Anticancer Res. | pmid:27354583 |
| Liu H et al. | Self-assembled dual-modality contrast agents for non-invasive stem cell tracking via near-infrared fluorescence and magnetic resonance imaging. | 2016 | J Colloid Interface Sci | pmid:27299677 |
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| Meng T et al. | A spermine conjugated stearic acid-g-chitosan oligosaccharide polymer with different types of amino groups for efficient p53 gene therapy. | 2016 | Colloids Surf B Biointerfaces | pmid:27289311 |
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| Afonso MS et al. | Dietary interesterified fat enriched with palmitic acid induces atherosclerosis by impairing macrophage cholesterol efflux and eliciting inflammation. | 2016 | J. Nutr. Biochem. | pmid:27142741 |
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| Wang HJ et al. | Prolongation of the degradation period and improvement of the angiogenesis of zein porous scaffolds in vivo. | 2016 | J Mater Sci Mater Med | pmid:26979976 |
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