stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Decalcification, Pathologic D003649 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


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Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Syamala US et al. Assessment of formulation factors on the release behaviour of BCS Class II drug from tablet dosage form using DoE. 2014 Curr Drug Deliv pmid:24975287
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Tadros MI and Fahmy RH Controlled-release triple anti-inflammatory therapy based on novel gastroretentive sponges: characterization and magnetic resonance imaging in healthy volunteers. 2014 Int J Pharm pmid:24928130
Uğurlu T and Halaçoğlu MD Effects of some lubricants and evaluation of compression parameters on directly compressible powders. 2014 Pharm Dev Technol pmid:23590449
Wang J et al. A soybean acyl carrier protein, GmACP, is important for root nodule symbiosis. 2014 Mol. Plant Microbe Interact. pmid:24400939
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Muzíková J and Sináglová P Comparison of properties of tablets and energy profile of compaction of two spray-dried lactoses. 2013 Jan-Feb Acta Pol Pharm pmid:23610968
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Mohamed IO Lipase-catalyzed acidolysis of palm mid fraction oil with palmitic and stearic Fatty Acid mixture for production of cocoa butter equivalent. 2013 Appl. Biochem. Biotechnol. pmid:23877586
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Emken E Human studies using isotope labeled fatty acids: answered and unanswered questions. 2013 J Oleo Sci pmid:23648399
Dangarembizi R et al. Aloe ferox seed: a potential source of oil for cosmetic and pharmaceutical use. 2013 Nat Prod Commun pmid:23678824
Maia M et al. A novel, direct, reagent-free method for the detection of beeswax adulteration by single-reflection attenuated total reflectance mid-infrared spectroscopy. 2013 Talanta pmid:23598195
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Nakagawa H et al. Real-time monitoring of lubrication properties of magnesium stearate using NIR spectrometer and thermal effusivity sensor. 2013 Int J Pharm pmid:23174413
Otsuka Y et al. Effects of polymorphic transformation on pharmaceutical properties of direct compressed tablets containing theophylline anhydrate bulk powder under high humidity. 2013 Colloids Surf B Biointerfaces pmid:23178204
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Delbecq F et al. N-stearoyl amino acid derivatives: potent biomimetic hydro/organogelators as templates for preparation of gold nanoparticles. 2013 J Colloid Interface Sci pmid:23089597
Fernandes CP et al. Triterpene esters and biological activities from edible fruits of Manilkara subsericea (Mart.) Dubard, Sapotaceae. 2013 Biomed Res Int pmid:23509702
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John CT et al. Formulating weakly basic HCl salts: relative ability of common excipients to induce disproportionation and the unique deleterious effects of magnesium stearate. 2013 Pharm. Res. pmid:23512680
Stank K and Steckel H Physico-chemical characterisation of surface modified particles for inhalation. 2013 Int J Pharm pmid:23518364
Kumar N et al. Salt dependent stability of stearic acid Langmuir-Blodgett films exposed to aqueous electrolytes. 2013 Langmuir pmid:23565719
Han SH et al. Bioinspired self-assembled peptide nanofibers with thermostable multivalent α-helices. 2013 Biomacromolecules pmid:23550841
Khan AA et al. Design, synthesis and in vitro anticancer evaluation of a stearic acid-based ester conjugate. 2013 Anticancer Res. pmid:23749903
Li C et al. Enhanced performance and interfacial investigation of mineral-based composite phase change materials for thermal energy storage. 2013 Sci Rep pmid:23712069
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Järvinen MA et al. Continuous direct tablet compression: effects of impeller rotation rate, total feed rate and drug content on the tablet properties and drug release. 2013 Drug Dev Ind Pharm pmid:23163644
Guo H et al. Self-assembled nanoparticles based on galactosylated O-carboxymethyl chitosan-graft-stearic acid conjugates for delivery of doxorubicin. 2013 Int J Pharm pmid:24140544
Cvetković Z et al. Distribution of plasma fatty acids is associated with response to chemotherapy in non-Hodgkin's lymphoma patients. 2013 Med. Oncol. pmid:24085546
Jin Q et al. A novel cationic microbubble coated with stearic acid-modified polyethylenimine to enhance DNA loading and gene delivery by ultrasound. 2013 PLoS ONE pmid:24086748
Eltayeb M et al. Electrosprayed core-shell polymer-lipid nanoparticles for active component delivery. 2013 Nanotechnology pmid:24164775
Boshtam M et al. Serum paraoxonase 1 activity is associated with fatty acid composition of high density lipoprotein. 2013 Dis. Markers pmid:24167374
Shibata E et al. Free fatty acids inhibit protein tyrosine phosphatase 1B and activate Akt. 2013 Cell. Physiol. Biochem. pmid:24107614
Wahl PR et al. Inline monitoring and a PAT strategy for pharmaceutical hot melt extrusion. 2013 Int J Pharm pmid:23911343
Michailidou VN et al. Anisotropic diffusion of concentrated hard-sphere colloids near a hard wall studied by evanescent wave dynamic light scattering. 2013 J Chem Phys pmid:24182077
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Yan J et al. Effect of proteins with different isoelectric points on the gene transfection efficiency mediated by stearic acid grafted chitosan oligosaccharide micelles. 2013 Mol. Pharm. pmid:23679858