| MeSH term | MeSH ID | Detail |
|---|---|---|
| Gallbladder Neoplasms | D005706 | 3 associated lipids |
| Calculi | D002137 | 3 associated lipids |
| Relapsing Fever | D012061 | 3 associated lipids |
| Yaws | D015001 | 4 associated lipids |
| Leukodystrophy, Metachromatic | D007966 | 4 associated lipids |
| Syphilis, Latent | D013592 | 4 associated lipids |
| Prostatic Diseases | D011469 | 4 associated lipids |
| Legionnaires' Disease | D007877 | 4 associated lipids |
| Chancroid | D002602 | 4 associated lipids |
| Boutonneuse Fever | D001907 | 5 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Desai D et al. | Evaluation of selected micronized poloxamers as tablet lubricants. | 2007 | Drug Deliv | pmid:17994358 |
| Maghsoodi M et al. | Improved compaction and packing properties of naproxen agglomerated crystals obtained by spherical crystallization technique. | 2007 | Drug Dev Ind Pharm | pmid:18058318 |
| Osman S et al. | Tetrasphaera remsis sp. nov., isolated from the Regenerative Enclosed Life Support Module Simulator (REMS) air system. | 2007 | Int. J. Syst. Evol. Microbiol. | pmid:18048719 |
| Ghosh SK et al. | Characterization and cloning of a stearoyl/oleoyl specific fatty acyl-acyl carrier protein thioesterase from the seeds of Madhuca longifolia (latifolia). | 2007 | Plant Physiol. Biochem. | pmid:17977002 |
| Cakir T et al. | Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia. | 2007 | Theor Biol Med Model | pmid:18070347 |
| Miyazaki M et al. | Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis. | 2007 | Cell Metab. | pmid:18054317 |
| Larsson KE et al. | LysoPC acyltransferase/PC transacylase activities in plant plasma membrane and plasma membrane-associated endoplasmic reticulum. | 2007 | BMC Plant Biol. | pmid:18045483 |
| Ruan HL et al. | Ferulic acid esters from Euphorbia hylonoma. | 2007 | Fitoterapia | pmid:17067756 |
| Nichols KK et al. | Identification of fatty acids and fatty acid amides in human meibomian gland secretions. | 2007 | Invest. Ophthalmol. Vis. Sci. | pmid:17197513 |
| Günther S et al. | Apicoplast lipoic acid protein ligase B is not essential for Plasmodium falciparum. | 2007 | PLoS Pathog. | pmid:18069893 |
| Forest PO et al. | Influence of gradual introduction of hydrophobic groups (stearic acid) in denatured atelocollagen on fibroblasts behavior in vitro. | 2007 | J Biomed Mater Res A | pmid:17133448 |
| Wong HL et al. | In vivo evaluation of a new polymer-lipid hybrid nanoparticle (PLN) formulation of doxorubicin in a murine solid tumor model. | 2007 | Eur J Pharm Biopharm | pmid:17156986 |
| Davies PN et al. | The determination of the mechanical strength of tablets of different shapes. | 2007 | Eur J Pharm Biopharm | pmid:17329086 |
| Maia MR et al. | Metabolism of polyunsaturated fatty acids and their toxicity to the microflora of the rumen. | 2007 | Antonie Van Leeuwenhoek | pmid:17072533 |
| Uehara Y et al. | Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element. | 2007 | Atherosclerosis | pmid:16730733 |
| Nolan LM et al. | Combined effects of iontophoretic and chemical enhancement on drug delivery. II. Transport across human and murine skin. | 2007 | Int J Pharm | pmid:17502130 |
| Shimizu K et al. | Characterization of tableting using the OSDRC system. | 2007 | Pharm. Res. | pmid:17554609 |
| Berry SE et al. | The solid fat content of stearic acid-rich fats determines their postprandial effects. | 2007 | Am. J. Clin. Nutr. | pmid:17556683 |
| Gorjão R et al. | Regulation of interleukin-2 signaling by fatty acids in human lymphocytes. | 2007 | J. Lipid Res. | pmid:17592174 |
| Anjos JL et al. | Effects of 1,8-cineole on the dynamics of lipids and proteins of stratum corneum. | 2007 | Int J Pharm | pmid:17600646 |
| Yang Y et al. | Regulation of FAT/CD36 mRNA gene expression by long chain fatty acids in the differentiated 3T3-L1 cells. | 2007 | Pediatr. Surg. Int. | pmid:17516074 |
| Young PM et al. | Effect of moisture on the compressibility and compactibility of sodium starch glycolate. | 2007 | Pharm Dev Technol | pmid:17510894 |
| Wei GH et al. | Rhizobialide: a new stearolactone produced by Mesorhizobium sp. CCNWGX022, a rhizobial endophyte from Glycyrrhiza uralensis. | 2007 | Chem. Biodivers. | pmid:17510984 |
| Teixeira AC et al. | Phase behaviour of stearic acid-stearonitrile mixtures. A thermodynamic study in bulk and at the air-water interface. | 2006 Nov-Dec | Chem. Phys. Lipids | pmid:17027948 |
| Wang Y and Wu W | In situ evading of phagocytic uptake of stealth solid lipid nanoparticles by mouse peritoneal macrophages. | 2006 May-Jun | Drug Deliv | pmid:16556570 |
| Uematsu Y et al. | Determination of magnesium stearate in capsule- or tablet-type supplements. | 2006 Mar-Apr | J AOAC Int | pmid:16640294 |
| KladnÃcková I et al. | Release of albumin from oligoester plastic matrices: effect of magnesium oxide and bivalent stearates. | 2006 Jan-Feb | Drug Deliv | pmid:16401590 |
| Fang Q et al. | Ascorbyl stearate inhibits cell proliferation and tumor growth in human ovarian carcinoma cells by targeting the PI3K/AKT pathway. | 2006 Jan-Feb | Anticancer Res. | pmid:16475700 |
| Templer J et al. | Influence of C18 long chain fatty acids on hydrogen metabolism. | 2006 Jan-Feb | Biotechnol. Prog. | pmid:16454511 |
| Pillai KG et al. | Spontaneous tooth exfoliation, maxillary osteomyelitis and facial scarring following trigeminal herpes zoster infection. | 2006 | Prim Dent Care | pmid:16836817 |
| Tavilani H et al. | Decreased polyunsaturated and increased saturated fatty acid concentration in spermatozoa from asthenozoospermic males as compared with normozoospermic males. | 2006 | Andrologia | pmid:16961570 |
| Grassi G et al. | Propaedeutic study for the delivery of nucleic acid-based molecules from PLGA microparticles and stearic acid nanoparticles. | 2006 | Int J Nanomedicine | pmid:17722283 |
| You JO et al. | Incorporation of quantum dots on virus in polycationic solution. | 2006 | Int J Nanomedicine | pmid:17722262 |
| Ramirez-Dorronsoro JC et al. | Chargeability measurements of selected pharmaceutical dry powders to assess their electrostatic charge control capabilities. | 2006 | AAPS PharmSciTech | pmid:17285749 |
| Föger F et al. | In vivo comparison of various polymeric and low molecular mass inhibitors of intestinal P-glycoprotein. | 2006 | Biomaterials | pmid:16919723 |
| Johansson TP and Leach GW | Sum frequency generation study of Langmuir Blodgett film architecture. | 2006 | J Phys Chem B | pmid:16913791 |
| Hsieh HJ et al. | Production of ascorbyl palmitate by surfactant-coated lipase in organic media. | 2006 | J. Agric. Food Chem. | pmid:16881677 |
| Anand M et al. | Synthesis and steric stabilization of silver nanoparticles in neat carbon dioxide solvent using fluorine-free compounds. | 2006 | J Phys Chem B | pmid:16869575 |
| Martinello T et al. | Optimization of poorly compactable drug tablets manufactured by direct compression using the mixture experimental design. | 2006 | Int J Pharm | pmid:16806756 |
| Gibon Y et al. | Integration of metabolite with transcript and enzyme activity profiling during diurnal cycles in Arabidopsis rosettes. | 2006 | Genome Biol. | pmid:16916443 |
| Kapuśniak J and Tomasik P | Lipid microencapsulation in starch. | 2006 | J Microencapsul | pmid:16801245 |
| Wong HG | Potential adverse and allergic reactions from complementary and alternative medicine and dietary supplements. | 2006 | Allergy Asthma Clin Immunol | pmid:20525159 |
| MacDonald AM and Lucy CA | Highly efficient protein separations in capillary electrophoresis using a supported bilayer/diblock copolymer coating. | 2006 | J Chromatogr A | pmid:16777117 |
| Dancey CP et al. | Nucleotide supplementation: a randomised double-blind placebo controlled trial of IntestAidIB in people with Irritable Bowel Syndrome [ISRCTN67764449]. | 2006 | Nutr J | pmid:16762076 |
| Douliez JP et al. | Self-assembly of fatty acid-alkylboladiamine salts. | 2006 | Langmuir | pmid:16401110 |
| Chen G | An exfoliated polyamide-6/layered double hydroxide nanocomposite via in situ intercalative polymerization between positively charged inorganic platelets. | 2006 | J Nanosci Nanotechnol | pmid:16736781 |
| Okazaki K et al. | The significance of C16 fatty acids in the sn-2 positions of glycerolipids in the photosynthetic growth of Synechocystis sp. PCC6803. | 2006 | Plant Physiol. | pmid:16603667 |
| Raith K et al. | Towards a molecular characterization of pharmaceutical excipients: mass spectrometric studies of ethoxylated surfactants. | 2006 | Int J Pharm | pmid:16730931 |
| Xu L et al. | A new triterpene and dibenzocyclooctadiene lignans from Schisandra propinqua (WALL.) BAILL. | 2006 | Chem. Pharm. Bull. | pmid:16595961 |
| Pérez-Vich B et al. | Molecular analysis of the high stearic acid content in sunflower mutant CAS-14. | 2006 | Theor. Appl. Genet. | pmid:16362273 |
| Urai M et al. | Structural analysis of an extracellular polysaccharide produced by Rhodococcus rhodochrous strain S-2. | 2006 | Carbohydr. Res. | pmid:16676419 |
| Zhu K et al. | Two aerobic pathways for the formation of unsaturated fatty acids in Pseudomonas aeruginosa. | 2006 | Mol. Microbiol. | pmid:16573679 |
| Shibata Y et al. | Fluidity and tableting characteristics of a powder solid dispersion of the low melting drugs ketoprofen and ibuprofen with crospovidone. | 2006 | Drug Dev Ind Pharm | pmid:16638683 |
| Capková P et al. | Structure of montmorillonite cointercalated with stearic acid and octadecylamine: modeling, diffraction, IR spectroscopy. | 2006 | J Colloid Interface Sci | pmid:16631185 |
| Wei Y et al. | Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16492686 |
| Wang Y et al. | Chronic effects of different non-esterified fatty acids on pancreatic islets of rats. | 2006 | Endocrine | pmid:16622307 |
| Khairuzzaman A et al. | Zero-order release of aspirin, theophylline and atenolol in water from novel methylcellulose glutarate matrix tablets. | 2006 | Int J Pharm | pmid:16621361 |
| Demirbas A et al. | Adsorption thermodynamics of stearic acid onto bentonite. | 2006 | J. Hazard. Mater. | pmid:16386845 |
| Wang Y et al. | Chain orientation and headgroup structure in Langmuir monolayers of stearic acid and metal stearate (Ag, Co, Zn, and Pb) studied by infrared reflection-absorption spectroscopy. | 2006 | J Chem Phys | pmid:16613467 |
| Mora PC et al. | Differential scanning calorimetry as a screening technique in compatibility studies of DHEA extended release formulations. | 2006 | J Pharm Biomed Anal | pmid:16574368 |
| Ding EL et al. | Chocolate and prevention of cardiovascular disease: a systematic review. | 2006 | Nutr Metab (Lond) | pmid:16390538 |
| Hasegawa T et al. | Molecular orientation analysis of a single-monolayer Langmuir-Blodgett film on a thin glass plate by infrared multiple-angle incidence resolution spectrometry. | 2006 | Anal. Chem. | pmid:16536405 |
| Serebryakova MV et al. | Mass spectrometric sequencing and acylation character analysis of C-terminal anchoring segment from Influenza A hemagglutinin. | 2006 | Eur J Mass Spectrom (Chichester) | pmid:16531651 |
| Fernandez-Moya V et al. | Lipid characterization of a high-stearic sunflower mutant displaying a seed stearic acid gradient. | 2006 | J. Agric. Food Chem. | pmid:19127733 |
| Vanholder T et al. | Effect of non-esterified fatty acids on bovine theca cell steroidogenesis and proliferation in vitro. | 2006 | Anim. Reprod. Sci. | pmid:15978752 |
| Garton NJ and Sutcliffe IC | Identification of a lipoarabinomannan-like lipoglycan in the actinomycete Gordonia bronchialis. | 2006 | Arch. Microbiol. | pmid:16320036 |
| Renaville B et al. | Eicosapentaenoic acid and 3,10 dithia stearic acid inhibit the desaturation of trans-vaccenic acid into cis-9, trans-11-conjugated linoleic acid through different pathways in Caco-2 and T84 cells. | 2006 | Br. J. Nutr. | pmid:16571147 |
| Fukuda S et al. | Augmentation of vaccenate production and suppression of vaccenate biohydrogenation in cultures of mixed ruminal microbes. | 2006 | J. Dairy Sci. | pmid:16507700 |
| Nazzal S and Khan MA | Controlled release of a self-emulsifying formulation from a tablet dosage form: stability assessment and optimization of some processing parameters. | 2006 | Int J Pharm | pmid:16563673 |
| Swaminathan V et al. | Measurement of the surface energy of lubricated pharmaceutical powders by inverse gas chromatography. | 2006 | Int J Pharm | pmid:16469458 |
| Barman S and Vasudevan S | Contrasting melting behavior of zinc stearate and zinc oleate. | 2006 | J Phys Chem B | pmid:16471580 |
| Wang ZJ et al. | Neuroprotective effect of the stearic acid against oxidative stress via phosphatidylinositol 3-kinase pathway. | 2006 | Chem. Biol. Interact. | pmid:16448636 |
| Mirmehrabi M et al. | Thermodynamic modeling of activity coefficient and prediction of solubility: Part 2. Semipredictive or semiempirical models. | 2006 | J Pharm Sci | pmid:16493593 |
| Mirmehrabi M et al. | Thermodynamic modeling of activity coefficient and prediction of solubility: Part 1. Predictive models. | 2006 | J Pharm Sci | pmid:16493594 |
| Matsumoto K et al. | Electron paramagnetic resonance decay constant and oxidative stresses in liver microsomes of the selenium-deficient rat. | 2006 | J. Nutr. Biochem. | pmid:16517143 |
| Carr TP and Jesch ED | Food components that reduce cholesterol absorption. | 2006 | Adv. Food Nutr. Res. | pmid:17011476 |
| Kurai J et al. | Acute eosinophilic pneumonia caused by calcium stearate, an additive agent for an oral antihistaminic medication. | 2006 | Intern. Med. | pmid:17016002 |
| Kamlekar RK and Swamy MJ | Studies on the critical micellar concentration and phase transitions of stearoylcarnitine. | 2006 | Biosci. Rep. | pmid:17029002 |
| Bunker MJ et al. | A nanoscale study of particle friction in a pharmaceutical system. | 2006 | Int J Pharm | pmid:16875789 |
| Li W et al. | Mass-balanced blend uniformity analysis of pharmaceutical powders by at-line near-infrared spectroscopy with a fiber-optic probe. | 2006 | Int J Pharm | pmid:16920283 |
| Ray K et al. | Distance-dependent metal-enhanced fluorescence from Langmuir-Blodgett monolayers of alkyl-NBD derivatives on silver island films. | 2006 | Langmuir | pmid:16981751 |
| Rasmussen HE et al. | Reduction in cholesterol absorption is enhanced by stearate-enriched plant sterol esters in hamsters. | 2006 | J. Nutr. | pmid:17056791 |
| Brouwer DH et al. | Size selective dustiness and exposure; simulated workplace comparisons. | 2006 | Ann Occup Hyg | pmid:16524926 |
| Biswas S et al. | Formation of complex films with water-soluble CTAB molecules. | 2006 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16549387 |
| Suresh Y and Das UN | Differential effect of saturated, monounsaturated, and polyunsaturated fatty acids on alloxan-induced diabetes mellitus. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16412622 |
| Azevedo-Martins AK et al. | Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells. | 2006 | Toxicol In Vitro | pmid:16644178 |
| iHoroz BB et al. | Influence of aluminum tristearate and sucrose stearate as the dispersing agents on physical properties and release characteristics of eudragit RS microspheres. | 2006 | AAPS PharmSciTech | pmid:16584146 |
| Hu FQ et al. | A novel chitosan oligosaccharide-stearic acid micelles for gene delivery: properties and in vitro transfection studies. | 2006 | Int J Pharm | pmid:16632285 |
| Schmidt WF et al. | Stearic acid solubility and cubic phase volume. | 2006 | Chem. Phys. Lipids | pmid:16616908 |
| Qi S et al. | An investigation into the interaction between taste masking fatty acid microspheres and alkaline buffer using thermal and spectroscopic analysis. | 2006 | J Pharm Sci | pmid:16552746 |
| Seitavuopio P et al. | Monitoring tablet surface roughness during the film coating process. | 2006 | AAPS PharmSciTech | pmid:16796349 |
| Lachiver ED et al. | Agglomeration tendency in dry pharmaceutical granular systems. | 2006 | Eur J Pharm Biopharm | pmid:16797949 |
| Titov VN et al. | [Fibrate-induced changes in the serum lipid contents of individual C16 and C18 fatty acids in patients with hyperlipidemia]. | 2006 | Klin. Lab. Diagn. | pmid:16756155 |
| Hu FQ et al. | Shell cross-linked stearic acid grafted chitosan oligosaccharide self-aggregated micelles for controlled release of paclitaxel. | 2006 | Colloids Surf B Biointerfaces | pmid:16759840 |
| Song MJ et al. | Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16781673 |
| Isaac G et al. | Sulfatide with short fatty acid dominates in astrocytes and neurons. | 2006 | FEBS J. | pmid:16623713 |
| Hu FQ et al. | Novel self-aggregates of chitosan oligosaccharide grafted stearic acid: preparation, characterization and protein association. | 2006 | Pharmazie | pmid:16599258 |
| Killen BU and Corrigan OI | Effect of soluble filler on drug release from stearic acid based compacts. | 2006 | Int J Pharm | pmid:16600537 |
| Zornetzer GA et al. | Solution structures of spinach acyl carrier protein with decanoate and stearate. | 2006 | Biochemistry | pmid:16618110 |
| Devillard E et al. | Rumen ciliate protozoa contain high concentrations of conjugated linoleic acids and vaccenic acid, yet do not hydrogenate linoleic acid or desaturate stearic acid. | 2006 | Br. J. Nutr. | pmid:17010229 |