stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Pneumoconiosis D011009 3 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Calculi D002137 3 associated lipids
Chancroid D002602 4 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Latent D013592 4 associated lipids
Prostatic Diseases D011469 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Alves M and Peric M An EPR study of the interfacial properties of phosphatidylcholine vesicles with different lipid chain lengths. 2006 Biophys. Chem. pmid:16517048
Grassi G et al. Propaedeutic study for the delivery of nucleic acid-based molecules from PLGA microparticles and stearic acid nanoparticles. 2006 Int J Nanomedicine pmid:17722283
Ramirez-Dorronsoro JC et al. Chargeability measurements of selected pharmaceutical dry powders to assess their electrostatic charge control capabilities. 2006 AAPS PharmSciTech pmid:17285749
Pérez-Vich B et al. Molecular analysis of the high stearic acid content in sunflower mutant CAS-14. 2006 Theor. Appl. Genet. pmid:16362273
Urai M et al. Structural analysis of an extracellular polysaccharide produced by Rhodococcus rhodochrous strain S-2. 2006 Carbohydr. Res. pmid:16676419
Shibata Y et al. Fluidity and tableting characteristics of a powder solid dispersion of the low melting drugs ketoprofen and ibuprofen with crospovidone. 2006 Drug Dev Ind Pharm pmid:16638683
Capková P et al. Structure of montmorillonite cointercalated with stearic acid and octadecylamine: modeling, diffraction, IR spectroscopy. 2006 J Colloid Interface Sci pmid:16631185
Wang Y et al. Chronic effects of different non-esterified fatty acids on pancreatic islets of rats. 2006 Endocrine pmid:16622307
Khairuzzaman A et al. Zero-order release of aspirin, theophylline and atenolol in water from novel methylcellulose glutarate matrix tablets. 2006 Int J Pharm pmid:16621361
Demirbas A et al. Adsorption thermodynamics of stearic acid onto bentonite. 2006 J. Hazard. Mater. pmid:16386845
Wang Y et al. Chain orientation and headgroup structure in Langmuir monolayers of stearic acid and metal stearate (Ag, Co, Zn, and Pb) studied by infrared reflection-absorption spectroscopy. 2006 J Chem Phys pmid:16613467
Mora PC et al. Differential scanning calorimetry as a screening technique in compatibility studies of DHEA extended release formulations. 2006 J Pharm Biomed Anal pmid:16574368
Ding EL et al. Chocolate and prevention of cardiovascular disease: a systematic review. 2006 Nutr Metab (Lond) pmid:16390538
Hasegawa T et al. Molecular orientation analysis of a single-monolayer Langmuir-Blodgett film on a thin glass plate by infrared multiple-angle incidence resolution spectrometry. 2006 Anal. Chem. pmid:16536405
Serebryakova MV et al. Mass spectrometric sequencing and acylation character analysis of C-terminal anchoring segment from Influenza A hemagglutinin. 2006 Eur J Mass Spectrom (Chichester) pmid:16531651
Zeman M et al. N-3 fatty acid supplementation decreases plasma homocysteine in diabetic dyslipidemia treated with statin-fibrate combination. 2006 J. Nutr. Biochem. pmid:16214329
Vanholder T et al. Effect of non-esterified fatty acids on bovine theca cell steroidogenesis and proliferation in vitro. 2006 Anim. Reprod. Sci. pmid:15978752
Nazzal S and Khan MA Controlled release of a self-emulsifying formulation from a tablet dosage form: stability assessment and optimization of some processing parameters. 2006 Int J Pharm pmid:16563673
Mirmehrabi M et al. Thermodynamic modeling of activity coefficient and prediction of solubility: Part 2. Semipredictive or semiempirical models. 2006 J Pharm Sci pmid:16493593
Mirmehrabi M et al. Thermodynamic modeling of activity coefficient and prediction of solubility: Part 1. Predictive models. 2006 J Pharm Sci pmid:16493594
Matsumoto K et al. Electron paramagnetic resonance decay constant and oxidative stresses in liver microsomes of the selenium-deficient rat. 2006 J. Nutr. Biochem. pmid:16517143
Carr TP and Jesch ED Food components that reduce cholesterol absorption. 2006 Adv. Food Nutr. Res. pmid:17011476
Kurai J et al. Acute eosinophilic pneumonia caused by calcium stearate, an additive agent for an oral antihistaminic medication. 2006 Intern. Med. pmid:17016002
Kamlekar RK and Swamy MJ Studies on the critical micellar concentration and phase transitions of stearoylcarnitine. 2006 Biosci. Rep. pmid:17029002
Bunker MJ et al. A nanoscale study of particle friction in a pharmaceutical system. 2006 Int J Pharm pmid:16875789
Li W et al. Mass-balanced blend uniformity analysis of pharmaceutical powders by at-line near-infrared spectroscopy with a fiber-optic probe. 2006 Int J Pharm pmid:16920283
Ray K et al. Distance-dependent metal-enhanced fluorescence from Langmuir-Blodgett monolayers of alkyl-NBD derivatives on silver island films. 2006 Langmuir pmid:16981751
Amakura Y et al. Characteristic long-chain fatty acid of Pleurocybella porrigens. 2006 Shokuhin Eiseigaku Zasshi pmid:16984039
Hu FQ et al. A novel chitosan oligosaccharide-stearic acid micelles for gene delivery: properties and in vitro transfection studies. 2006 Int J Pharm pmid:16632285
Schmidt WF et al. Stearic acid solubility and cubic phase volume. 2006 Chem. Phys. Lipids pmid:16616908
Qi S et al. An investigation into the interaction between taste masking fatty acid microspheres and alkaline buffer using thermal and spectroscopic analysis. 2006 J Pharm Sci pmid:16552746
Seitavuopio P et al. Monitoring tablet surface roughness during the film coating process. 2006 AAPS PharmSciTech pmid:16796349
Lachiver ED et al. Agglomeration tendency in dry pharmaceutical granular systems. 2006 Eur J Pharm Biopharm pmid:16797949
Titov VN et al. [Fibrate-induced changes in the serum lipid contents of individual C16 and C18 fatty acids in patients with hyperlipidemia]. 2006 Klin. Lab. Diagn. pmid:16756155
Hu FQ et al. Shell cross-linked stearic acid grafted chitosan oligosaccharide self-aggregated micelles for controlled release of paclitaxel. 2006 Colloids Surf B Biointerfaces pmid:16759840
Song MJ et al. Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes. 2006 Biochem. Biophys. Res. Commun. pmid:16781673
Isaac G et al. Sulfatide with short fatty acid dominates in astrocytes and neurons. 2006 FEBS J. pmid:16623713
Desrosiers Lachiver E et al. Insights into the role of electrostatic forces on the behavior of dry pharmaceutical particulate systems. 2006 Pharm. Res. pmid:16715390
Tönges L et al. Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons. 2006 RNA pmid:16699166
Devillard E et al. Rumen ciliate protozoa contain high concentrations of conjugated linoleic acids and vaccenic acid, yet do not hydrogenate linoleic acid or desaturate stearic acid. 2006 Br. J. Nutr. pmid:17010229
Gelders GG et al. Potato phosphorylase catalyzed synthesis of amylose-lipid complexes. 2005 Sep-Oct Biomacromolecules pmid:16153100
Parra-Barraza H et al. Chitosan-cholesterol and chitosan-stearic acid interactions at the air-water interface. 2005 Sep-Oct Biomacromolecules pmid:16153076
Stanisz B The influence of pharmaceutical excipients on quinapril hydrochloride stability. 2005 May-Jun Acta Pol Pharm pmid:16193811
Menéndez R et al. In vitro and in vivo study of octacosanol metabolism. 2005 Mar-Apr Arch. Med. Res. pmid:15847942
Staiger H et al. Fatty acid-induced differential regulation of the genes encoding peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in human skeletal muscle cells that have been differentiated in vitro. 2005 Diabetologia pmid:16132959
Arai T and Hosoi Y [Determination of magnesium stearate in pharmaceutical preparations using derivatization with 2-nitrophenylhydrazine and HPLC]. 2005 Yakugaku Zasshi pmid:15738629
Watanabe L et al. Structural insights for fatty acid binding in a Lys49-phospholipase A2: crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid. 2005 Biochimie pmid:15760708
Schreiner T et al. Immediate drug release from solid oral dosage forms. 2005 J Pharm Sci pmid:15761936
Risé P et al. Differential modulation by simvastatin of the metabolic pathways in the n-9, n-6 and n-3 fatty acid series, in human monocytic and hepatocytic cell lines. 2005 Biochem. Pharmacol. pmid:15763545
Liu FX et al. [Study on the encapsulation technique of high purity gamma-linolenic acid, part 1--saponification reaction and saponification value]. 2005 Zhongguo Zhong Yao Za Zhi pmid:15806965
Fabianowski W et al. Integrated circuits protection with the Langmuir-Blodgett Films. 2005 Bioelectrochemistry pmid:15833702
Grabowski A et al. Characterization of long-chain fatty-acid-degrading syntrophic associations from a biodegraded oil reservoir. 2005 Res. Microbiol. pmid:15939576
Wurster DE et al. The influence of magnesium stearate on the Hiestand Tableting Indices and other related mechanical properties of maltodextrins. 2005 Pharm Dev Technol pmid:16370175
Fukami J et al. Development of fast disintegrating compressed tablets using amino acid as disintegration accelerator: evaluation of wetting and disintegration of tablet on the basis of surface free energy. 2005 Chem. Pharm. Bull. pmid:16327184
Salzman RA et al. Transcriptional profiling of sorghum induced by methyl jasmonate, salicylic acid, and aminocyclopropane carboxylic acid reveals cooperative regulation and novel gene responses. 2005 Plant Physiol. pmid:15863699
Wyttenbach N et al. Drug-excipient compatibility testing using a high-throughput approach and statistical design. 2005 Pharm Dev Technol pmid:16370179
Vueba ML et al. Role of cellulose ether polymers on ibuprofen release from matrix tablets. 2005 Drug Dev Ind Pharm pmid:16207613
Turkoglu M et al. Evaluation of hexagonal boron nitride as a new tablet lubricant. 2005 Pharm Dev Technol pmid:16176018
Chen Y et al. Side reactions in controlling the quality, yield, and stability of high quality colloidal nanocrystals. 2005 J. Am. Chem. Soc. pmid:16173766
Wang X et al. Solid state characteristics of ternary solid dispersions composed of PVP VA64, Myrj 52 and itraconazole. 2005 Int J Pharm pmid:16105723
Barkai G et al. Community prescribing and resistant Streptococcus pneumoniae. 2005 Emerging Infect. Dis. pmid:15963276
Dong J et al. Silver carboxylate nanostructure nucleation and growth on AgBr crystals. 2005 Nanotechnology pmid:21727481
Hosaka S et al. Effect of compression on interaction between 1,4-dihydropyridine compounds and lactose monohydrate. 2005 Chem. Pharm. Bull. pmid:15863920
Verma RK and Garg S Selection of excipients for extended release formulations of glipizide through drug-excipient compatibility testing. 2005 J Pharm Biomed Anal pmid:15967291
Shim SK et al. Analysis of cellular fatty acids in Orientia tsutsugamushi as taxonomic markers. 2005 Microbiol. Immunol. pmid:15840959
Savickas A and Bernatoniene J Optimization of "Askoeziuofito" tablets. 2005 Medicina (Kaunas) pmid:15827390
Staiger K et al. Insulin and its analogue glargine do not affect viability and proliferation of human coronary artery endothelial and smooth muscle cells. 2005 Diabetologia pmid:16078017
Morais S et al. Dietary protein:lipid ratio and lipid nature affects fatty acid absorption and metabolism in a teleost larva. 2005 Br. J. Nutr. pmid:16022750
Armoni M et al. Free fatty acids repress the GLUT4 gene expression in cardiac muscle via novel response elements. 2005 J. Biol. Chem. pmid:16096283
Desbrosses GG et al. Lotus japonicus metabolic profiling. Development of gas chromatography-mass spectrometry resources for the study of plant-microbe interactions. 2005 Plant Physiol. pmid:15749991
Li D et al. Plasma coagulation factor VII activity and its correlates in healthy men. 2005 Eur J Clin Nutr pmid:16106263
Citadini AP et al. EPR studies of chlorocatechol 1,2-dioxygenase: evidences of iron reduction during catalysis and of the binding of amphipatic molecules. 2005 Biophys. J. pmid:15722436
Serrano-Vega MJ et al. Lipid characterization of seed oils from high-palmitic, low-palmitoleic, and very high-stearic acid sunflower lines. 2005 Lipids pmid:16028719
Nkondjock A et al. Specific fatty acid intake and the risk of pancreatic cancer in Canada. 2005 Br. J. Cancer pmid:15685231
Zadmard R and Schrader T Nanomolar protein sensing with embedded receptor molecules. 2005 J. Am. Chem. Soc. pmid:15656628
Afonso C et al. Structural characterization of fatty acids cationized with copper by electrospray ionization mass spectrometry under low-energy collision-induced dissociation. 2005 J Mass Spectrom pmid:15674862
Fichtner F et al. Particle size distribution and evolution in tablet structure during and after compaction. 2005 Int J Pharm pmid:15725568
Xie FM et al. [Preparation of stearic acid solid lipid nanoparticles containing podophyllotoxin]. 2005 Di Yi Jun Yi Da Xue Xue Bao pmid:15684011
Cury-Boaventura MF and Curi R Regulation of reactive oxygen species (ROS) production by C18 fatty acids in Jurkat and Raji cells. 2005 Clin. Sci. pmid:15563273
Vanholder T et al. Effect of non-esterified fatty acids on bovine granulosa cell steroidogenesis and proliferation in vitro. 2005 Anim. Reprod. Sci. pmid:15885439
Li W and Worosila GD Quantitation of active pharmaceutical ingredients and excipients in powder blends using designed multivariate calibration models by near-infrared spectroscopy. 2005 Int J Pharm pmid:15848006
Muzíková J and Páleník L [A study of the properties of compacts from a mixed dry binder on the base of alpha-lactose monohydrate and microcrystalline cellulose]. 2005 Ceska Slov Farm pmid:15945458
Zhu S et al. Acid soap and phase behavior of stearic acid and triethanolamine stearate. 2005 J Phys Chem B pmid:16852443
Sampath H and Ntambi JM The fate and intermediary metabolism of stearic acid. 2005 Lipids pmid:16477801
Kris-Etherton PM et al. Dietary stearic acid and risk of cardiovascular disease: intake, sources, digestion, and absorption. 2005 Lipids pmid:16477802
Mensink RP Effects of stearic acid on plasma lipid and lipoproteins in humans. 2005 Lipids pmid:16477803
Sanders TA and Berry SE Influence of stearic acid on postprandial lipemia and hemostatic function. 2005 Lipids pmid:16477806
Tholstrup T Influence of stearic acid on hemostatic risk factors in humans. 2005 Lipids pmid:16477807
Ehling S et al. Formation of acrylamide from lipids. 2005 Adv. Exp. Med. Biol. pmid:16438301
Le Jossic-Corcos C et al. Hepatic farnesyl diphosphate synthase expression is suppressed by polyunsaturated fatty acids. 2005 Biochem. J. pmid:15473864
Mishra R and Simonson MS Saturated free fatty acids and apoptosis in microvascular mesangial cells: palmitate activates pro-apoptotic signaling involving caspase 9 and mitochondrial release of endonuclease G. 2005 Cardiovasc Diabetol pmid:15642122
Csallany AS et al. Effect of high stearic acid containing fat on markers for in vivo lipid peroxidation. 2005 Int J Food Sci Nutr pmid:16638661
Hong J et al. The short-term effect of fatty acids on glucagon secretion is influenced by their chain length, spatial configuration, and degree of unsaturation: studies in vitro. 2005 Metab. Clin. Exp. pmid:16154432
Thijssen MA and Mensink RP Small differences in the effects of stearic acid, oleic acid, and linoleic acid on the serum lipoprotein profile of humans. 2005 Am. J. Clin. Nutr. pmid:16155261
Rao KP et al. Impact of solid-state properties on lubrication efficacy of magnesium stearate. 2005 Pharm Dev Technol pmid:16176023
Leroy JL et al. Non-esterified fatty acids in follicular fluid of dairy cows and their effect on developmental capacity of bovine oocytes in vitro. 2005 Reproduction pmid:16183866
Jonat S et al. Influence of compacted hydrophobic and hydrophilic colloidal silicon dioxide on tableting properties of pharmaceutical excipients. 2005 Drug Dev Ind Pharm pmid:16207616
Jurkiewicz K Adsorptive bubble separation of zinc and cadmium cations in presence of ferric and aluminum hydroxides. 2005 J Colloid Interface Sci pmid:15897071
Choi MY et al. Pheromone biosynthetic pathways in the moths Heliothis subflexa and Heliothis virescens. 2005 Arch. Insect Biochem. Physiol. pmid:15898118
Iwahashi M et al. Dynamical dimer structure and liquid structure of fatty acids in their binary liquid mixture: decanoic/octadecanoic acid and decanoic/dodecanoic acid systems. 2005 Chem. Phys. Lipids pmid:15642581