| MeSH term | MeSH ID | Detail |
|---|---|---|
| Brain Ischemia | D002545 | 89 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Haghjou N et al. | Sustained release intraocular drug delivery devices for treatment of uveitis. | 2011 | J Ophthalmic Vis Res | pmid:22454753 |
| Potta SG et al. | Preparation and characterization of ibuprofen solid lipid nanoparticles with enhanced solubility. | 2011 | J Microencapsul | pmid:21171818 |
| Mosca M et al. | Effect of membrane composition on lipid oxidation in liposomes. | 2011 | Chem. Phys. Lipids | pmid:21185813 |
| de Lima-Salgado TM et al. | Molecular mechanisms by which saturated fatty acids modulate TNF-α expression in mouse macrophage lineage. | 2011 | Cell Biochem. Biophys. | pmid:20809180 |
| James J et al. | Two-dimensional surface properties of PEO-PPO-PEO triblock copolymer film at the air/water interface in the absence and presence of Tyr-Phe dipeptide, Val-Tyr-Val tripeptide, SDS and stearic acid. | 2011 | Colloids Surf B Biointerfaces | pmid:20888193 |
| Zhang Y and Clapp A | Overview of stabilizing ligands for biocompatible quantum dot nanocrystals. | 2011 | Sensors (Basel) | pmid:22247651 |
| Jishnu V et al. | Formulation and evaluation of cephalexin extended release matrix tablets using 3 factorial design. | 2011 | J Young Pharm | pmid:22224031 |
| Oosterveer MH et al. | Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function. | 2011 | Nutr Metab (Lond) | pmid:22201701 |
| Chen M et al. | [Study on the chemical constituents from Fructus Toosendan (III)]. | 2011 | Zhong Yao Cai | pmid:22500422 |
| Wu DJ et al. | Metabonomics-based omics study and atherosclerosis. | 2011 | J Clin Bioinforma | pmid:22040517 |
| Walash MI et al. | Development and validation of stability indicating method for determination of sertraline following ICH guidlines and its determination in pharmaceuticals and biological fluids. | 2011 | Chem Cent J | pmid:21996025 |
| Raza A and Zia-Ul-Haq M | Application of Certain π-Acceptors for the Spectrophotometric Determination of Alendronate Sodium in Pharmaceutical Bulk and Dosage Forms. | 2011 | Int J Anal Chem | pmid:21760789 |
| Abdulrahman SA and Basavaiah K | Sensitive and selective spectrophotometric determination of gabapentin in capsules using two nitrophenols as chromogenic agents. | 2011 | Int J Anal Chem | pmid:21760787 |
| Zenita O and Basavaiah K | Utility of N-bromosuccinimide for the titrimetric and spectrophotometric determination of famotidine in pharmaceutical formulations. | 2011 | Int J Anal Chem | pmid:21760785 |
| Almer G et al. | Adiponectin-coated nanoparticles for enhanced imaging of atherosclerotic plaques. | 2011 | Int J Nanomedicine | pmid:21753879 |
| Brown JD et al. | VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses. | 2011 | PLoS ONE | pmid:21750705 |
| Amaya KR et al. | Small molecule analysis and imaging of fatty acids in the zebra finch song system using time-of-flight-secondary ion mass spectrometry. | 2011 | J. Neurochem. | pmid:21496023 |
| Duangjit S et al. | Characterization and In Vitro Skin Permeation of Meloxicam-Loaded Liposomes versus Transfersomes. | 2011 | J Drug Deliv | pmid:21490750 |
| Liu Y et al. | Graphene and graphene oxide: two ideal choices for the enrichment and ionization of long-chain fatty acids free from matrix-assisted laser desorption/ionization matrix interference. | 2011 | Rapid Commun. Mass Spectrom. | pmid:22006384 |
| Fabiano A et al. | Metabolomic analysis of bronchoalveolar lavage fluid in preterm infants complicated by respiratory distress syndrome: preliminary results. | 2011 | J. Matern. Fetal. Neonatal. Med. | pmid:21781003 |
| Watanabe H et al. | Biosynthetic Pathway for Sex Pheromone Components Produced in a Plusiinae Moth, Plusia festucae. | 2011 | Front Endocrinol (Lausanne) | pmid:22649385 |
| Yee JK et al. | Organ-specific alterations in fatty acid de novo synthesis and desaturation in a rat model of programmed obesity. | 2011 | Lipids Health Dis | pmid:21569358 |
| Shivanand K et al. | In vivo bioavailability studies of sumatriptan succinate buccal tablets. | 2011 | Daru | pmid:22615661 |
| Gande S and Rao Y | Sustained-release effervescent floating matrix tablets of baclofen: development, optimization and in vitro-in vivo evaluation in healthy human volunteers. | 2011 | Daru | pmid:22615658 |
| Varshosaz J et al. | Development of novel budesonide pellets based on CODES(TM) technology: In vitro/in vivo evaluation in induced colitis in rats. | 2011 | Daru | pmid:22615647 |
| Dey S et al. | Formulation and optimization of sustained release Stavudine microspheres using response surface methodology. | 2011 | ISRN Pharm | pmid:22389855 |
| Prajapati ST et al. | Formulation and evaluation of controlled-release tablet of zolpidem tartrate by melt granulation technique. | 2011 | ISRN Pharm | pmid:22389845 |
| Flowers MT et al. | Metabolic changes in skin caused by Scd1 deficiency: a focus on retinol metabolism. | 2011 | PLoS ONE | pmid:21573029 |
| Kouskoumvekaki I and Panagiotou G | Navigating the human metabolome for biomarker identification and design of pharmaceutical molecules. | 2011 | J. Biomed. Biotechnol. | pmid:20936122 |
| Wang GG et al. | Self-assembled biomimetic superhydrophobic CaCO3 coating inspired from fouling mineralization in geothermal water. | 2011 | Langmuir | pmid:21919516 |
| Asahi H et al. | Plasmodium falciparum: differing effects of non-esterified fatty acids and phospholipids on intraerythrocytic growth in serum-free medium. | 2011 | Exp. Parasitol. | pmid:21095186 |
| MacDonald AM et al. | A modified supported bilayer/diblock polymer--working towards a tunable coating for capillary electrophoresis. | 2011 | J Chromatogr A | pmid:21122870 |
| Liu X et al. | Synthesis of high quality and stability CdS quantum dots with overlapped nucleation-growth process in large scale. | 2011 | J Colloid Interface Sci | pmid:21040929 |
| Tamilvanan S et al. | In vitro and in vivo evaluation of hydrophilic and hydrophobic polymers-based nicorandil-loaded peroral tablet compared with its once-daily commercial sustained-release tablet. | 2011 | Drug Dev Ind Pharm | pmid:20923389 |
| Li Y et al. | Building layer-by-layer 3D supramolecular nanostructures at the terephthalic acid/stearic acid interface. | 2011 | Chem. Commun. (Camb.) | pmid:21755081 |
| Kumar A et al. | Phytochemical investigation and antifeedant activity of Premna latifolia leaves. | 2011 | Nat. Prod. Res. | pmid:21756197 |
| Hirose A et al. | Clofibric acid increases the formation of oleic acid in endoplasmic reticulum of the liver of rats. | 2011 | J. Pharmacol. Sci. | pmid:21757842 |
| Choi SE et al. | Capsaicin attenuates palmitate-induced expression of macrophage inflammatory protein 1 and interleukin 8 by increasing palmitate oxidation and reducing c-Jun activation in THP-1 (human acute monocytic leukemia cell) cells. | 2011 | Nutr Res | pmid:21745629 |
| Fameau AL et al. | Smart foams: switching reversibly between ultrastable and unstable foams. | 2011 | Angew. Chem. Int. Ed. Engl. | pmid:21780260 |
| Gremos S et al. | Direct enzymatic acylation of cellulose pretreated in BMIMCl ionic liquid. | 2011 | Bioresour. Technol. | pmid:20888759 |
| Perrault M et al. | An experimental investigation of the effect of the amount of lubricant on tablet properties. | 2011 | Drug Dev Ind Pharm | pmid:20704461 |
| Peng Q et al. | A novel esterase gene cloned from a metagenomic library from neritic sediments of the South China Sea. | 2011 | Microb. Cell Fact. | pmid:22067554 |
| Yu WL et al. | Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. | 2011 | Microb. Cell Fact. | pmid:22047615 |
| Sekharan TR et al. | Formulation and Evaluation of Hydroxypropyl Methylcellulose-based Controlled Release Matrix Tablets for Theophylline. | 2011 | Indian J Pharm Sci | pmid:22707833 |
| Nagarsekar KS et al. | Antioxidant and antilipid peroxidation potential of supercritical fluid extract and ethanol extract of leaves of vitex negundo linn. | 2011 | Indian J Pharm Sci | pmid:22707827 |
| Mercado FV et al. | Phase diagram of mixed monolayers of stearic acid and dimyristoylphosphatidylcholine. Effect of the acid ionization. | 2011 | Chem. Phys. Lipids | pmid:21635875 |
| Abbasi M et al. | siRNA-mediated down-regulation of P-glycoprotein in a Xenograft tumor model in NOD-SCID mice. | 2011 | Pharm. Res. | pmid:21638135 |
| Lan DM et al. | A novel cold-active lipase from Candida albicans: cloning, expression and characterization of the recombinant enzyme. | 2011 | Int J Mol Sci | pmid:21747717 |
| Lee YJ and Jenkins TC | Biohydrogenation of linolenic acid to stearic acid by the rumen microbial population yields multiple intermediate conjugated diene isomers. | 2011 | J. Nutr. | pmid:21653571 |
| Sloat BR et al. | In vitro and in vivo anti-tumor activities of a gemcitabine derivative carried by nanoparticles. | 2011 | Int J Pharm | pmid:21371545 |