| MeSH term | MeSH ID | Detail |
|---|---|---|
| Brain Ischemia | D002545 | 89 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhang JW et al. | [Studies on the chemical constituents of Toricellia angulata var. intermedia]. | 2010 | Zhong Yao Cai | pmid:21434432 |
| Fang X et al. | Development and analysis of an in vivo-compatible metabolic network of Mycobacterium tuberculosis. | 2010 | BMC Syst Biol | pmid:21092312 |
| Westerbacka J et al. | Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease. | 2010 | Gastroenterology | pmid:20600015 |
| Even P et al. | Postprandial effects of a lipid-rich meal in the rat are modulated by the degree of unsaturation of 18C fatty acids. | 2010 | Metab. Clin. Exp. | pmid:19775712 |
| Liu TY and Lin YL | Novel pH-sensitive chitosan-based hydrogel for encapsulating poorly water-soluble drugs. | 2010 | Acta Biomater | pmid:19819354 |
| Kiss H et al. | Complete genome sequence of Denitrovibrio acetiphilus type strain (N2460). | 2010 | Stand Genomic Sci | pmid:21304711 |
| Jain S et al. | Development of a floating dosage form of ranitidine hydrochloride by statistical optimization technique. | 2010 | J Young Pharm | pmid:21264091 |
| Naumova EA et al. | Influence of individual saliva secretion on fluoride bioavailability. | 2010 | Open Dent J | pmid:21221176 |
| Patel BP et al. | Formulation and evaluation of mouth dissolving tablets of cinnarizine. | 2010 | Indian J Pharm Sci | pmid:21218071 |
| Liu RS and Tang YJ | Quantitative analysis for the effect of plant oil and fatty acid on Tuber melanosporum culture by uniform design combined with partial least squares regression. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20473608 |
| Sorek N et al. | An S-acylation switch of conserved G domain cysteines is required for polarity signaling by ROP GTPases. | 2010 | Curr. Biol. | pmid:20451389 |
| Murate M et al. | Phosphatidylglucoside forms specific lipid domains on the outer leaflet of the plasma membrane. | 2010 | Biochemistry | pmid:20433166 |
| Sun H et al. | Complete genome sequence of Desulfarculus baarsii type strain (2st14). | 2010 | Stand Genomic Sci | pmid:21304732 |
| Zhou QT et al. | Improving aerosolization of drug powders by reducing powder intrinsic cohesion via a mechanical dry coating approach. | 2010 | Int J Pharm | pmid:20435112 |
| Cohn JS et al. | Reduction in intestinal cholesterol absorption by various food components: mechanisms and implications. | 2010 | Atheroscler Suppl | pmid:20439167 |
| Pantusa M and Bartucci R | Kinetics of stearic acid transfer between human serum albumin and sterically stabilized liposomes. | 2010 | Eur. Biophys. J. | pmid:20306030 |
| Pennick G et al. | Superior effect of isostearyl isostearate on improvement in stratum corneum water permeability barrier function as examined by the plastic occlusion stress test. | 2010 | Int J Cosmet Sci | pmid:20642769 |
| Wieder DR and Pattimakiel L | Examining the efficacy, safety, and patient acceptability of the combined contraceptive vaginal ring (NuvaRing). | 2010 | Int J Womens Health | pmid:21151688 |
| Remya K et al. | Formulation development, evaluation and comparative study of effects of super disintegrants in cefixime oral disintegrating tablets. | 2010 | J Young Pharm | pmid:21042477 |
| Sateesha S et al. | Influence of Organic Acids on Diltiazem HCl Release Kinetics from Hydroxypropyl Methyl Cellulose Matrix Tablets. | 2010 | J Young Pharm | pmid:21042476 |
| Hurko O et al. | Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice. | 2010 | Int J Alzheimers Dis | pmid:20981353 |
| Bolton B and Halpern BP | Orthonasal and retronasal but not oral-cavity-only discrimination of vapor-phase fatty acids. | 2010 | Chem. Senses | pmid:20100787 |
| Lu L et al. | Near infrared spectroscopy of stearic acid adsorbed on montmorillonite. | 2010 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:20071218 |
| Roblegg E et al. | Development of lipophilic calcium stearate pellets using ibuprofen as model drug. | 2010 | Eur J Pharm Biopharm | pmid:20080179 |
| Rao KS and Srinivas K | RP-HPLC Method for the Determination of Losartan Potassium and Ramipril in Combined Dosage Form. | 2010 | Indian J Pharm Sci | pmid:20582199 |
| Pan PH et al. | Stearic acid attenuates cholestasis-induced liver injury. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20036638 |
| Keny RV et al. | Formulation and evaluation of rizatriptan benzoate mouth disintegrating tablets. | 2010 | Indian J Pharm Sci | pmid:20582194 |
| Zhou YY et al. | Preparation and pharmacodynamics of stearic acid and poly (lactic-co-glycolic acid) grafted chitosan oligosaccharide micelles for 10-hydroxycamptothecin. | 2010 | Int J Pharm | pmid:20420886 |
| Eftaiha AF et al. | Bioadhesive controlled metronidazole release matrix based on chitosan and xanthan gum. | 2010 | Mar Drugs | pmid:20559494 |
| Wu T et al. | Study on superhydrophobic hybrids fabricated from multiwalled carbon nanotubes and stearic acid. | 2010 | J Colloid Interface Sci | pmid:20427047 |
| Normand-Lauzière F et al. | Increased postprandial nonesterified fatty acid appearance and oxidation in type 2 diabetes is not fully established in offspring of diabetic subjects. | 2010 | PLoS ONE | pmid:20532041 |
| Rivera CA et al. | Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis. | 2010 | BMC Gastroenterol | pmid:20509914 |
| Barupal DK et al. | Hydrocarbon phenotyping of algal species using pyrolysis-gas chromatography mass spectrometry. | 2010 | BMC Biotechnol. | pmid:20492649 |
| Saravanakumari P and Mani K | Structural characterization of a novel xylolipid biosurfactant from Lactococcus lactis and analysis of antibacterial activity against multi-drug resistant pathogens. | 2010 | Bioresour. Technol. | pmid:20637606 |
| Invernizzi G et al. | Sustained upregulation of stearoyl-CoA desaturase in bovine mammary tissue with contrasting changes in milk fat synthesis and lipogenic gene networks caused by lipid supplements. | 2010 | Funct. Integr. Genomics | pmid:20607344 |
| Chon B et al. | Shell and ligand-dependent blinking of CdSe-based core/shell nanocrystals. | 2010 | Phys Chem Chem Phys | pmid:20607188 |
| Lin SY et al. | Solid-state transformation of different gabapentin polymorphs upon milling and co-milling. | 2010 | Int J Pharm | pmid:20561572 |
| Bunn RC et al. | Palmitate and insulin synergistically induce IL-6 expression in human monocytes. | 2010 | Cardiovasc Diabetol | pmid:21054880 |
| Asai T and Fujimoto Y | Cyclic fatty acyl glycosides in the glandular trichome exudate of Silene gallica. | 2010 | Phytochemistry | pmid:20541780 |
| Foster SP and Johnson CP | Feeding and hemolymph trehalose concentration influence sex pheromone production in virgin Heliothis virescens moths. | 2010 | J. Insect Physiol. | pmid:20540946 |
| Nokhodchi A et al. | Physico-mechanical and dissolution behaviours of ibuprofen crystals crystallized in the presence of various additives. | 2010 | Daru | pmid:22615598 |
| Milanovic J et al. | Microencapsulation of flavors in carnauba wax. | 2010 | Sensors (Basel) | pmid:22315575 |
| Jun HY et al. | Long residence time of ultrasound microbubbles targeted to integrin in murine tumor model. | 2010 | Acad Radiol | pmid:19815430 |
| Jian WX et al. | [Detection and analysis on plasma metabolomics in patient with coronary heart disease of Xin-blood stasis syndrome pattern]. | 2010 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:20815270 |
| Lai TY et al. | Alterations in serum fatty acid concentrations and desaturase activities in Bietti crystalline dystrophy unaffected by CYP4V2 genotypes. | 2010 | Invest. Ophthalmol. Vis. Sci. | pmid:19797200 |
| Gonzalez-Mira E et al. | Design and ocular tolerance of flurbiprofen loaded ultrasound-engineered NLC. | 2010 | Colloids Surf B Biointerfaces | pmid:20719479 |
| Chakraborty S et al. | Utilization of adsorption technique in the development of oral delivery system of lipid based nanoparticles. | 2010 | Colloids Surf B Biointerfaces | pmid:20728320 |
| Tripathi B et al. | Fortification of sorghum (Sorghum vulgare) and pearl millet (Pennisetum glaucum) flour with zinc. | 2010 | J Trace Elem Med Biol | pmid:20685098 |
| Kuo WT et al. | Polymeric micelles comprising stearic acid-grafted polyethyleneimine as nonviral gene carriers. | 2010 | J Nanosci Nanotechnol | pmid:21133072 |
| Thomas CP et al. | Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. | 2010 | J. Biol. Chem. | pmid:20061396 |