| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uterine Neoplasms | D014594 | 18 associated lipids |
| Urticaria | D014581 | 13 associated lipids |
| Urethritis | D014526 | 9 associated lipids |
| Tuberculosis, Pulmonary | D014397 | 18 associated lipids |
| Tremor | D014202 | 15 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Tenosynovitis | D013717 | 3 associated lipids |
| Syphilis, Latent | D013592 | 4 associated lipids |
| Syphilis, Congenital | D013590 | 3 associated lipids |
| Spinal Cord Injuries | D013119 | 34 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mason P et al. | SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids. | 2012 | PLoS ONE | pmid:22457791 |
| Zhu S et al. | Lysosomal delivery of a lipophilic gemcitabine prodrug using novel acid-sensitive micelles improved its antitumor activity. | 2012 | Bioconjug. Chem. | pmid:22471294 |
| Itoh Y and Hasegawa T | Polarization dependence of Raman scattering from a thin film involving optical anisotropy theorized for molecular orientation analysis. | 2012 | J Phys Chem A | pmid:22551093 |
| Akinsete JA et al. | Consumption of high ω-3 fatty acid diet suppressed prostate tumorigenesis in C3(1) Tag mice. | 2012 | Carcinogenesis | pmid:22045025 |
| Eili M et al. | Degradability enhancement of poly(lactic acid) by stearate-Zn(3)Al LDH nanolayers. | 2012 | Int J Mol Sci | pmid:22942682 |
| Hayashi Y et al. | Latent structure analysis of the process variables and pharmaceutical responses of an orally disintegrating tablet. | 2012 | Chem. Pharm. Bull. | pmid:22878814 |
| Brown PN et al. | Determination of major phenolic compounds in Echinacea spp. raw materials and finished products by high-performance liquid chromatography with ultraviolet detection: single-laboratory validation matrix extension. | 2011 Sep-Oct | J AOAC Int | pmid:22165004 |
| Tomuta I et al. | High-Throughput NIR-Chemometric Method for Meloxicam Assay from Powder Blends for Tableting. | 2011 Oct-Dec | Sci Pharm | pmid:22145112 |
| Nanjwade BK et al. | Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs. | 2011 Oct-Dec | Sci Pharm | pmid:22145101 |
| Jelvehgari M et al. | Formulation, characterization and in vitro evaluation of theophylline-loaded Eudragit RS 100 microspheres prepared by an emulsion-solvent diffusion/evaporation technique. | 2011 Nov-Dec | Pharm Dev Technol | pmid:20722498 |
| Qu WX et al. | Analysis of fatty acids in A. szechenyianum Gay. by microwave-assisted extraction and gas chromatography-mass spectrometry. | 2011 May-Jun | Phytochem Anal | pmid:20848395 |
| Nath B et al. | Preparation and in vitro dissolution profile of zidovudine loaded microspheres made of Eudragit RS 100, RL 100 and their combinations. | 2011 May-Jun | Acta Pol Pharm | pmid:21648196 |
| BozdaÄŸ-Pehlivan S et al. | Evaluation of drug-excipient interaction in the formulation of celecoxib tablets. | 2011 May-Jun | Acta Pol Pharm | pmid:21648198 |
| Malik K et al. | Taste masked microspheres of ofloxacin: formulation and evaluation of orodispersible tablets. | 2011 Jul-Sep | Sci Pharm | pmid:21886910 |
| Zaid AN et al. | Formulation and bioequivalence of two valsartan tablets after a single oral administration. | 2011 Jan-Mar | Sci Pharm | pmid:21617777 |
| Shah DA et al. | Stability indicating LC-method for estimation of paracetamol and lornoxicam in combined dosage form. | 2011 Jan-Mar | Sci Pharm | pmid:21617776 |
| Fodorová M et al. | Structural features of lipid A of Rickettsia typhi. | 2011 | Acta Virol. | pmid:21434703 |
| Ropero J et al. | Near-infrared chemical imaging slope as a new method to study tablet compaction and tablet relaxation. | 2011 | Appl Spectrosc | pmid:21396195 |
| Junk MJ et al. | DEER in biological multispin-systems: a case study on the fatty acid binding to human serum albumin. | 2011 | J. Magn. Reson. | pmid:21450500 |
| Franch-Lage F et al. | Fast assessment of the surface distribution of API and excipients in tablets using NIR-hyperspectral imaging. | 2011 | Int J Pharm | pmid:21419207 |
| Xu QC et al. | Enhanced photocatalytic activity of C-N-codoped TiO2 films prepared via an organic-free approach. | 2011 | J. Hazard. Mater. | pmid:21316842 |
| Zhou QT et al. | Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approach. | 2011 | J Pharm Sci | pmid:21455980 |
| Sheikh KA et al. | Influence of hydration state and homologue composition of magnesium stearate on the physical chemical properties of liquid paraffin lipogels. | 2011 | Int J Pharm | pmid:21457766 |
| Wang S et al. | Insertion of an esterase gene into a specific locust pathogen (Metarhizium acridum) enables it to infect caterpillars. | 2011 | PLoS Pathog. | pmid:21731492 |
| Paczkowski S and Schütz S | Post-mortem volatiles of vertebrate tissue. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21720824 |
| Wahjudi PN et al. | Turnover of nonessential fatty acids in cardiolipin from the rat heart. | 2011 | J. Lipid Res. | pmid:21957203 |
| Haghjou N et al. | Sustained release intraocular drug delivery devices for treatment of uveitis. | 2011 | J Ophthalmic Vis Res | pmid:22454753 |
| Paul D et al. | Proteome and membrane fatty acid analyses on Oligotropha carboxidovorans OM5 grown under chemolithoautotrophic and heterotrophic conditions. | 2011 | PLoS ONE | pmid:21386900 |
| James J et al. | Two-dimensional surface properties of PEO-PPO-PEO triblock copolymer film at the air/water interface in the absence and presence of Tyr-Phe dipeptide, Val-Tyr-Val tripeptide, SDS and stearic acid. | 2011 | Colloids Surf B Biointerfaces | pmid:20888193 |
| Ely DR and Carvajal MT | Determination of the scale of segregation of low dose tablets using hyperspectral imaging. | 2011 | Int J Pharm | pmid:21601625 |
| Neji SB et al. | Esterification of fatty acid over Tunisian acid activated clay: kinetic study. | 2011 | J Oleo Sci | pmid:21606617 |
| Whitney TR et al. | Redberry juniper as a roughage source in lamb feedlot rations: wool and carcass characteristics, meat fatty acid profiles, and sensory panel traits. | 2011 | Meat Sci. | pmid:21570776 |
| Yalcin H et al. | Effect of gamma-irradiation on some chemical characteristics and volatile content of linseed. | 2011 | J Med Food | pmid:21548804 |
| Dong Z et al. | Preparation and in vitro, in vivo evaluations of norfloxacin-loaded solid lipid nanopartices for oral delivery. | 2011 | Drug Deliv | pmid:21554156 |
| Oosterveer MH et al. | Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function. | 2011 | Nutr Metab (Lond) | pmid:22201701 |
| Zhang Y et al. | α-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytes. | 2011 | Lipids Health Dis | pmid:21592363 |
| Ting TC et al. | Increased lipogenesis and stearate accelerate vascular calcification in calcifying vascular cells. | 2011 | J. Biol. Chem. | pmid:21596756 |
| Man TY et al. | Dietary manipulation reveals an unexpected inverse relationship between fat mass and adipose 11β-hydroxysteroid dehydrogenase type 1. | 2011 | Am. J. Physiol. Endocrinol. Metab. | pmid:21406612 |
| Pingali K et al. | Evaluation of strain-induced hydrophobicity of pharmaceutical blends and its effect on drug release rate under multiple compression conditions. | 2011 | Drug Dev Ind Pharm | pmid:20942612 |
| Arora G et al. | Formulation and evaluation of controlled release matrix mucoadhesive tablets of domperidone using Salvia plebeian gum. | 2011 | J Adv Pharm Technol Res | pmid:22171313 |
| Sathiyaraj S et al. | Lornoxicam gastro retentive floating matrix tablets: Design and in vitro evaluation. | 2011 | J Adv Pharm Technol Res | pmid:22171312 |
| Chen M et al. | [Study on the chemical constituents from Fructus Toosendan (III)]. | 2011 | Zhong Yao Cai | pmid:22500422 |
| Wu DJ et al. | Metabonomics-based omics study and atherosclerosis. | 2011 | J Clin Bioinforma | pmid:22040517 |
| Walash MI et al. | Development and validation of stability indicating method for determination of sertraline following ICH guidlines and its determination in pharmaceuticals and biological fluids. | 2011 | Chem Cent J | pmid:21996025 |
| El-Enany NM et al. | Spectrofluorimetric determination of sertraline in dosage forms and human plasma through derivatization with 9-fluorenylmethyl chloroformate. | 2011 | Chem Cent J | pmid:21978386 |
| D'Ambrosio DN et al. | Distinct populations of hepatic stellate cells in the mouse liver have different capacities for retinoid and lipid storage. | 2011 | PLoS ONE | pmid:21949825 |
| Nurul Syazana MS et al. | Antiproliferative effect of methanolic extraction of tualang honey on human keloid fibroblasts. | 2011 | BMC Complement Altern Med | pmid:21943200 |
| Rajpurohit H et al. | Hordeum vulgare hull in the design of fast disintegrating tablets. | 2011 | J Young Pharm | pmid:21897660 |
| Tachibana H | Green tea polyphenol sensing. | 2011 | Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. | pmid:21422740 |
| Brown JD et al. | VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses. | 2011 | PLoS ONE | pmid:21750705 |
| Fernandez C et al. | Altered desaturation and elongation of fatty acids in hormone-sensitive lipase null mice. | 2011 | PLoS ONE | pmid:21738729 |
| Singhal A et al. | Colon-targeted quercetin delivery using natural polymer to enhance its bioavailability. | 2011 | Pharmacognosy Res | pmid:21731393 |
| Li FQ et al. | A novel spray-dried nanoparticles-in-microparticles system for formulating scopolamine hydrobromide into orally disintegrating tablets. | 2011 | Int J Nanomedicine | pmid:21720502 |
| Eggerath J et al. | EDX-Element Analysis of the In Vitro Effect of Fluoride Oral Hygiene Tablets on Artificial Caries Lesion Formation and Remineralization in Human Enamel. | 2011 | Open Dent J | pmid:21687564 |
| Amaya KR et al. | Small molecule analysis and imaging of fatty acids in the zebra finch song system using time-of-flight-secondary ion mass spectrometry. | 2011 | J. Neurochem. | pmid:21496023 |
| Duangjit S et al. | Characterization and In Vitro Skin Permeation of Meloxicam-Loaded Liposomes versus Transfersomes. | 2011 | J Drug Deliv | pmid:21490750 |
| Kumaravelrajan R et al. | Development and evaluation of controlled porosity osmotic pump for nifedipine and metoprolol combination. | 2011 | Lipids Health Dis | pmid:21477386 |
| Kordyukova LV et al. | Linker and/or transmembrane regions of influenza A/Group-1, A/Group-2, and type B virus hemagglutinins are packed differently within trimers. | 2011 | Biochim. Biophys. Acta | pmid:21420932 |
| Wang L et al. | Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations. | 2011 | AIDS Res Ther | pmid:21385339 |
| Salem H et al. | Nanosized rods agglomerates as a new approach for formulation of a dry powder inhaler. | 2011 | Int J Nanomedicine | pmid:21383856 |
| Gresback R et al. | Combined plasma gas-phase synthesis and colloidal processing of InP/ZnS core/shell nanocrystals. | 2011 | Nanoscale Res Lett | pmid:21711589 |
| Dey S et al. | Formulation and optimization of sustained release Stavudine microspheres using response surface methodology. | 2011 | ISRN Pharm | pmid:22389855 |
| Prajapati ST et al. | Formulation and evaluation of controlled-release tablet of zolpidem tartrate by melt granulation technique. | 2011 | ISRN Pharm | pmid:22389845 |
| Kulinowski P et al. | Magnetic resonance imaging and image analysis for assessment of HPMC matrix tablets structural evolution in USP Apparatus 4. | 2011 | Pharm. Res. | pmid:21181545 |
| Christian F et al. | Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes. | 2011 | J. Biol. Chem. | pmid:21177871 |
| Mantzaris MD et al. | Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells. | 2011 | FEBS J. | pmid:21182590 |
| Liu D et al. | Synthesis and characterization of upconverting NaYF4:Er3+, Yb3+ nanocrystals via thermal decomposition of stearate precursor. | 2011 | J Nanosci Nanotechnol | pmid:22413291 |
| Han L et al. | Starch stearate as a novel encapsulation wall material and its effect on oil-water interfacial tension. | 2011 | J Control Release | pmid:22195872 |
| Gallardo LA et al. | Effect of europium(II) stearate on the mechanical properties and the oxidation resistance of UHMWPE. | 2011 | J Mech Behav Biomed Mater | pmid:21565729 |
| Abdel-Mottaleb MM et al. | Lipid nanocapsules for dermal application: a comparative study of lipid-based versus polymer-based nanocarriers. | 2011 | Eur J Pharm Biopharm | pmid:21558002 |
| Yoo JY et al. | A randomized controlled trial of oral phosphate binders in the treatment of pseudoxanthoma elasticum. | 2011 | J. Am. Acad. Dermatol. | pmid:21496949 |
| MužÃková J and Eimerová I | A study of the compaction process and the properties of tablets made of a new co-processed starch excipient. | 2011 | Drug Dev Ind Pharm | pmid:21469946 |
| Yoshida MI et al. | Thermal behavior study and decomposition kinetics of amiodarone hydrochloride under isothermal conditions. | 2011 | Drug Dev Ind Pharm | pmid:21449701 |
| Kushner J et al. | Examining the impact of excipient material property variation on drug product quality attributes: a quality-by-design study for a roller compacted, immediate release tablet. | 2011 | J Pharm Sci | pmid:21319161 |
| de Sousa Neto D et al. | Effect of the ω-acylceramides on the lipid organization of stratum corneum model membranes evaluated by X-ray diffraction and FTIR studies (Part I). | 2011 | Chem. Phys. Lipids | pmid:21238439 |
| Liu H et al. | A surfactant-free recipe for shape-controlled synthesis of CdSe nanocrystals. | 2011 | Nanotechnology | pmid:21169661 |
| de Morais e Silva FA et al. | Rosacea fulminans in pregnancy with ocular perforation. | 2011 | J Dtsch Dermatol Ges | pmid:21366860 |
| Choi SE et al. | Capsaicin attenuates palmitate-induced expression of macrophage inflammatory protein 1 and interleukin 8 by increasing palmitate oxidation and reducing c-Jun activation in THP-1 (human acute monocytic leukemia cell) cells. | 2011 | Nutr Res | pmid:21745629 |
| Fameau AL et al. | Smart foams: switching reversibly between ultrastable and unstable foams. | 2011 | Angew. Chem. Int. Ed. Engl. | pmid:21780260 |
| Li S et al. | Preparation, characterization, pharmacokinetics and tissue distribution of solid lipid nanoparticles loaded with tetrandrine. | 2011 | AAPS PharmSciTech | pmid:21811889 |
| Klein CM and Jenkins TC | Docosahexaenoic acid elevates trans-18:1 isomers but is not directly converted into trans-18:1 isomers in ruminal batch cultures. | 2011 | J. Dairy Sci. | pmid:21854940 |
| Waters LJ et al. | Controlled microwave processing applied to the pharmaceutical formulation of ibuprofen. | 2011 | AAPS PharmSciTech | pmid:21842309 |
| Tuei VC et al. | Effects of human serum albumin complexed with free fatty acids on cell viability and insulin secretion in the hamster pancreatic β-cell line HIT-T15. | 2011 | Life Sci. | pmid:21396379 |
| Corvis Y et al. | Physicochemical stability of solid dispersions of enantiomeric or racemic ibuprofen in stearic acid. | 2011 | J Pharm Sci | pmid:21905027 |
| Gao Q et al. | Synthesis and characterization of novel amphiphilic copolymer stearic acid-coupled F127 nanoparticles for nano-technology based drug delivery system. | 2011 | Colloids Surf B Biointerfaces | pmid:21906917 |
| Khan FN and Dehghan MH | Enhanced bioavailability of atorvastatin calcium from stabilized gastric resident formulation. | 2011 | AAPS PharmSciTech | pmid:21879394 |
| Varshosaz J et al. | Lipid nanocapsule-based gels for enhancement of transdermal delivery of ketorolac tromethamine. | 2011 | J Drug Deliv | pmid:22175029 |
| Perrault M et al. | An experimental investigation of the effect of the amount of lubricant on tablet properties. | 2011 | Drug Dev Ind Pharm | pmid:20704461 |
| Süntar I et al. | Wound Healing Activity of Rubus sanctus Schreber (Rosaceae): Preclinical Study in Animal Models. | 2011 | Evid Based Complement Alternat Med | pmid:19755505 |
| Du YZ et al. | Quaternary complexes composed of plasmid DNA/protamine/fish sperm DNA/stearic acid grafted chitosan oligosaccharide micelles for gene delivery. | 2011 | Int. J. Biol. Macromol. | pmid:21035503 |
| Bhattacharjee A et al. | Deposition of stearate-oleate rich seed fat in Mangifera indica is mediated by a FatA type acyl-ACP thioesterase. | 2011 | Phytochemistry | pmid:21130480 |
| Yuan H et al. | Stearic acid-g-chitosan polymeric micelle for oral drug delivery: in vitro transport and in vivo absorption. | 2011 | Mol. Pharm. | pmid:21138243 |
| Sekharan TR et al. | Formulation and Evaluation of Hydroxypropyl Methylcellulose-based Controlled Release Matrix Tablets for Theophylline. | 2011 | Indian J Pharm Sci | pmid:22707833 |
| Nagarsekar KS et al. | Antioxidant and antilipid peroxidation potential of supercritical fluid extract and ethanol extract of leaves of vitex negundo linn. | 2011 | Indian J Pharm Sci | pmid:22707827 |
| Bazzini AA et al. | Metabolic and miRNA profiling of TMV infected plants reveals biphasic temporal changes. | 2011 | PLoS ONE | pmid:22174812 |
| Masareddy R et al. | Development of Orodispersible Tizanidine HCl Tablets Using Spray Dried Coprocessed Exipient Bases. | 2011 | Indian J Pharm Sci | pmid:22707822 |
| Göker M et al. | Complete genome sequence of the thermophilic sulfur-reducer Desulfurobacterium thermolithotrophum type strain (BSA(T)) from a deep-sea hydrothermal vent. | 2011 | Stand Genomic Sci | pmid:22675590 |
| Lan DM et al. | A novel cold-active lipase from Candida albicans: cloning, expression and characterization of the recombinant enzyme. | 2011 | Int J Mol Sci | pmid:21747717 |
| Lee YJ and Jenkins TC | Biohydrogenation of linolenic acid to stearic acid by the rumen microbial population yields multiple intermediate conjugated diene isomers. | 2011 | J. Nutr. | pmid:21653571 |
| Sloat BR et al. | In vitro and in vivo anti-tumor activities of a gemcitabine derivative carried by nanoparticles. | 2011 | Int J Pharm | pmid:21371545 |