MeSH term | MeSH ID | Detail |
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Obesity, Abdominal | D056128 | 3 associated lipids |
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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LAMBIOTTE M | [USE OF RADIOACTIVE CHOLESTEROL IN THE STUDY OF THE INFLUENCE OF DIETARY LIPIDS ON CHOLESTEROL METABOLISM]. | 1963 | Ann Nutr Aliment | pmid:14048747 |
SHIFRINE M and MARR AG | THE REQUIREMENT OF FATTY ACIDS BY PITYROSPORUM OVALE. | 1963 | J. Gen. Microbiol. | pmid:14053273 |
RAZIN S and ROTTEM S | FATTY ACID REQUIREMENTS OF MYCOPLASMA LAIDLAWII. | 1963 | J. Gen. Microbiol. | pmid:14114935 |
BLOMSTRAND R et al. | BIOHYDROGENATION IN GERM-FREE RATS. | 1963 Jul-Aug | J Atheroscler Res | pmid:14051792 |
ULLMANN E et al. | [STUDIES ON THE STABILITY OF PENICILLIN G SODIUM IN THE PRESENCE OF IONOGENIC TENSIDES, ORGANIC GEL FORMERS AND PRESERVATIVE AGENTS. 7. COMMUNICATION ON THE INFLUENCE OF ADJUVANTS IN DRUG COMPOUNDING]. | 1963 Jul-Aug | Pharm Acta Helv | pmid:14052353 |
LEFEBVRE P and HENRIOUL F | [INFLUENCE OF GLUCAGON ON THE BLOOD LEVEL AND ARTERIO-VENOUS DIFFERENCE OF UNESTERIFIED FATTY ACIDS]. | 1963 Sep-Oct | Ann. Endocrinol. (Paris) | pmid:14092350 |
HAMMONDS TW and SHONE G | THE SEPARATION OF FATTY ACID METHYL ESTERS (INCLUDING "CRITICAL PAIRS") BY THIN-LAYER PARTITION CHROMATOGRAPHY. | 1964 | J. Chromatogr. | pmid:14205938 |
PILZ H and JATZKEWITZ H | [DETERMINATION OF C18- AND C24-SPHINGOMYELIN BY THIN-LAYER CHROMATOGRAPHY IN NORMAL AND PATHOLOGICAL BRAINS, INCLUDING A CASE OF NIEMANN-PICK DISEASE]. | 1964 | J. Neurochem. | pmid:14206462 |
WILLEBRANDS AF | MYOCARDIAL EXTRACTION OF INDIVIDUAL NON-ESTERIFIED FATTY ACIDS, ESTERIFIED FATTY ACIDS AND ACETOACETATE IN THE FASTING HUMAN. | 1964 | Clin. Chim. Acta | pmid:14230940 |
TIETZ A et al. | A NEW PTERIDINE-REQUIRING ENZYME SYSTEM FOR THE OXIDATION OF GLYCERYL ETHERS. | 1964 | J. Biol. Chem. | pmid:14247652 |