stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Obesity, Abdominal D056128 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Fodorová M et al. Structural features of lipid A of Rickettsia typhi. 2011 Acta Virol. pmid:21434703
Sasaki T and Tanaka S Adsorption behavior of some aromatic compounds on hydrophobic magnetite for magnetic separation. 2011 J. Hazard. Mater. pmid:21962863
Ropero J et al. Near-infrared chemical imaging slope as a new method to study tablet compaction and tablet relaxation. 2011 Appl Spectrosc pmid:21396195
Junk MJ et al. DEER in biological multispin-systems: a case study on the fatty acid binding to human serum albumin. 2011 J. Magn. Reson. pmid:21450500
Franch-Lage F et al. Fast assessment of the surface distribution of API and excipients in tablets using NIR-hyperspectral imaging. 2011 Int J Pharm pmid:21419207
Xu QC et al. Enhanced photocatalytic activity of C-N-codoped TiO2 films prepared via an organic-free approach. 2011 J. Hazard. Mater. pmid:21316842
Zhou QT et al. Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approach. 2011 J Pharm Sci pmid:21455980
Jeon JH et al. Novel lipolytic enzymes identified from metagenomic library of deep-sea sediment. 2011 Evid Based Complement Alternat Med pmid:21845199
Sheikh KA et al. Influence of hydration state and homologue composition of magnesium stearate on the physical chemical properties of liquid paraffin lipogels. 2011 Int J Pharm pmid:21457766
Jing F et al. Phylogenetic and experimental characterization of an acyl-ACP thioesterase family reveals significant diversity in enzymatic specificity and activity. 2011 BMC Biochem. pmid:21831316
Severino P et al. Polymorphism, crystallinity and hydrophilic-lipophilic balance of stearic acid and stearic acid-capric/caprylic triglyceride matrices for production of stable nanoparticles. 2011 Colloids Surf B Biointerfaces pmid:21543196
Zhou QT et al. Investigation of the extent of surface coating via mechanofusion with varying additive levels and the influences on bulk powder flow properties. 2011 Int J Pharm pmid:21527321
Manzano E et al. Study of the GC-MS determination of the palmitic-stearic acid ratio for the characterisation of drying oil in painting: La Encarnación by Alonso Cano as a case study. 2011 Talanta pmid:21530791
Prabhakar N et al. Polyaniline Langmuir-Blodgett film based aptasensor for ochratoxin A detection. 2011 Biosens Bioelectron pmid:21514815
Fini A et al. Diclofenac salts, part 6: release from lipid microspheres. 2011 J Pharm Sci pmid:21523784
Veit M and Thaa B Association of influenza virus proteins with membrane rafts. 2011 Adv Virol pmid:22312341
Wadher KJ et al. Formulation and evaluation of a sustained-release tablets of metformin hydrochloride using hydrophilic synthetic and hydrophobic natural polymers. 2011 Indian J Pharm Sci pmid:22303065
Park MY et al. Hog millet (Panicum miliaceum L.)-supplemented diet ameliorates hyperlipidemia and hepatic lipid accumulation in C57BL/6J-ob/ob mice. 2011 Nutr Res Pract pmid:22259675
Basu B et al. Formulation and evaluation of fast dissolving tablets of cinnarizine using superdisintegrant blends and subliming material. 2011 J Adv Pharm Technol Res pmid:22247895
Ely DR and Carvajal MT Determination of the scale of segregation of low dose tablets using hyperspectral imaging. 2011 Int J Pharm pmid:21601625
Guan Q et al. Preparation and pharmacokinetics of solid lipid nanoparticles loaded with pueraria flavones. 2011 J Control Release pmid:22195890
Zhang Y and Clapp A Overview of stabilizing ligands for biocompatible quantum dot nanocrystals. 2011 Sensors (Basel) pmid:22247651
Neji SB et al. Esterification of fatty acid over Tunisian acid activated clay: kinetic study. 2011 J Oleo Sci pmid:21606617
Whitney TR et al. Redberry juniper as a roughage source in lamb feedlot rations: wool and carcass characteristics, meat fatty acid profiles, and sensory panel traits. 2011 Meat Sci. pmid:21570776
Yalcin H et al. Effect of gamma-irradiation on some chemical characteristics and volatile content of linseed. 2011 J Med Food pmid:21548804
Dong Z et al. Preparation and in vitro, in vivo evaluations of norfloxacin-loaded solid lipid nanopartices for oral delivery. 2011 Drug Deliv pmid:21554156
Zhang Y et al. α-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytes. 2011 Lipids Health Dis pmid:21592363
Ting TC et al. Increased lipogenesis and stearate accelerate vascular calcification in calcifying vascular cells. 2011 J. Biol. Chem. pmid:21596756
Pingali K et al. Evaluation of strain-induced hydrophobicity of pharmaceutical blends and its effect on drug release rate under multiple compression conditions. 2011 Drug Dev Ind Pharm pmid:20942612
Sharma S et al. RP-HPLC Method for Simultaneous Estimation of Nitazoxanide and Ofloxacin in Tablets. 2011 Indian J Pharm Sci pmid:22131628
Lavigne JP et al. Propolis can potentialise the anti-adhesion activity of proanthocyanidins on uropathogenic Escherichia coli in the prevention of recurrent urinary tract infections. 2011 BMC Res Notes pmid:22126300
Steidl S et al. Mâ‚… muscarinic receptors mediate striatal dopamine activation by ventral tegmental morphine and pedunculopontine stimulation in mice. 2011 PLoS ONE pmid:22102904
Meissner M et al. Bile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rate. 2011 PLoS ONE pmid:22087215
Guschina I et al. Lipid classes and fatty acid patterns are altered in the brain of γ-synuclein null mutant mice. 2011 Lipids pmid:20963507
Yin AW and Huang SJ [Research on chemical constituents of xuefu zhuyu decoction]. 2011 Zhong Yao Cai pmid:22372145
Bailey JA et al. Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons. 2011 PLoS ONE pmid:21799757
Protière M et al. Rational design of the gram-scale synthesis of nearly monodisperse semiconductor nanocrystals. 2011 Nanoscale Res Lett pmid:21791060
Rajendraprasad N et al. Titrimetric and spectrophotometric assay of oxcarbazepine in pharmaceuticals using N-bromosuccinimide and bromopyrogallol red. 2011 Int J Anal Chem pmid:21785594
Bhope SG et al. Design and development of a stable polyherbal formulation based on the results of compatibility studies. 2011 Pharmacognosy Res pmid:21772756
Williams KJ et al. The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo. 2011 Tuberculosis (Edinb) pmid:21764638
Zhang H et al. Seed Oil of Brucea javanica Induces Apoptotic Death of Acute Myeloid Leukemia Cells via Both the Death Receptors and the Mitochondrial-Related Pathways. 2011 Evid Based Complement Alternat Med pmid:21760826
Raza A and Zia-Ul-Haq M Application of Certain π-Acceptors for the Spectrophotometric Determination of Alendronate Sodium in Pharmaceutical Bulk and Dosage Forms. 2011 Int J Anal Chem pmid:21760789
Ip K et al. Analysis of complex metabolic behavior through pathway decomposition. 2011 BMC Syst Biol pmid:21639889
Ion G et al. Effects of canola and corn oil mimetic on Jurkat cells. 2011 Lipids Health Dis pmid:21631947
Yang J et al. Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: implications on anti-glucagon therapies for diabetes. 2011 BMC Genomics pmid:21631939
Roberts LD et al. The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue. 2011 Genome Biol. pmid:21843327
Chabukswar A et al. Six sigma: process of understanding the control and capability of ranitidine hydrochloride tablet. 2011 J Young Pharm pmid:21607050
Lacaze C et al. The initial pharmaceutical development of an artesunate/amodiaquine oral formulation for the treatment of malaria: a public-private partnership. 2011 Malar. J. pmid:21605361
Houmard JA et al. Is there a metabolic program in the skeletal muscle of obese individuals? 2011 J Obes pmid:21603262
Li C et al. Prevention of carcinogenesis and inhibition of breast cancer tumor burden by dietary stearate. 2011 Carcinogenesis pmid:21586513
Mahdi ES et al. Effect of surfactant and surfactant blends on pseudoternary phase diagram behavior of newly synthesized palm kernel oil esters. 2011 Drug Des Devel Ther pmid:21792294
Kalinina OV et al. Combinations of protein-chemical complex structures reveal new targets for established drugs. 2011 PLoS Comput. Biol. pmid:21573205
Sahu SK et al. Hydrophobically modified carboxymethyl chitosan nanoparticles targeted delivery of paclitaxel. 2011 J Drug Target pmid:20367067
Liu Y et al. Graphene and graphene oxide: two ideal choices for the enrichment and ionization of long-chain fatty acids free from matrix-assisted laser desorption/ionization matrix interference. 2011 Rapid Commun. Mass Spectrom. pmid:22006384
Wang Y et al. [Analysis of plasma metabonomics of mini-swines with qi deficiency and blood stasis syndrome due to chronic myocardial ischemia]. 2011 Zhong Xi Yi Jie He Xue Bao pmid:21288451
Islam A and Ehsan A Comparison of suture material and technique of closure of subcutaneous fat and skin in caesarean section. 2011 N Am J Med Sci pmid:22540072
Green CD and Olson LK Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic β-cells by stearoyl-CoA desaturase and Elovl6. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:21266672
Santos GM et al. Negative regulation by nuclear receptors: a plethora of mechanisms. 2011 Trends Endocrinol. Metab. pmid:21196123
Watanabe H et al. Biosynthetic Pathway for Sex Pheromone Components Produced in a Plusiinae Moth, Plusia festucae. 2011 Front Endocrinol (Lausanne) pmid:22649385
Gilani K et al. Development of respirable nanomicelle carriers for delivery of amphotericin B by jet nebulization. 2011 J Pharm Sci pmid:20602350
Liu D et al. Synthesis and characterization of upconverting NaYF4:Er3+, Yb3+ nanocrystals via thermal decomposition of stearate precursor. 2011 J Nanosci Nanotechnol pmid:22413291
Pniewski T et al. Low-dose oral immunization with lyophilized tissue of herbicide-resistant lettuce expressing hepatitis B surface antigen for prototype plant-derived vaccine tablet formulation. 2011 J. Appl. Genet. pmid:21107787
Peter A et al. Relationships between hepatic stearoyl-CoA desaturase-1 activity and mRNA expression with liver fat content in humans. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:21045174
Han L et al. Starch stearate as a novel encapsulation wall material and its effect on oil-water interfacial tension. 2011 J Control Release pmid:22195872
Dasu MR and Jialal I Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20959532
Kouskoumvekaki I and Panagiotou G Navigating the human metabolome for biomarker identification and design of pharmaceutical molecules. 2011 J. Biomed. Biotechnol. pmid:20936122
Goto T et al. Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. 2011 Biochem. J. pmid:21605082
Kasliwal N et al. Formulation, development, and performance evaluation of metoclopramide HCl oro-dispersible sustained release tablet. 2011 Arch. Pharm. Res. pmid:22076769
Abdel-Mottaleb MM et al. Lipid nanocapsules for dermal application: a comparative study of lipid-based versus polymer-based nanocarriers. 2011 Eur J Pharm Biopharm pmid:21558002
Yoo JY et al. A randomized controlled trial of oral phosphate binders in the treatment of pseudoxanthoma elasticum. 2011 J. Am. Acad. Dermatol. pmid:21496949
Mužíková J and Eimerová I A study of the compaction process and the properties of tablets made of a new co-processed starch excipient. 2011 Drug Dev Ind Pharm pmid:21469946
Yoshida MI et al. Thermal behavior study and decomposition kinetics of amiodarone hydrochloride under isothermal conditions. 2011 Drug Dev Ind Pharm pmid:21449701
Kushner J et al. Examining the impact of excipient material property variation on drug product quality attributes: a quality-by-design study for a roller compacted, immediate release tablet. 2011 J Pharm Sci pmid:21319161
de Sousa Neto D et al. Effect of the ω-acylceramides on the lipid organization of stratum corneum model membranes evaluated by X-ray diffraction and FTIR studies (Part I). 2011 Chem. Phys. Lipids pmid:21238439
Seow LJ et al. Anti-angiogenic activity of Gynura segetum leaf extracts and its fractions. 2011 J Ethnopharmacol pmid:21167271
Price ER et al. Carnitine palmitoyl transferase activity and whole muscle oxidation rates vary with fatty acid substrate in avian flight muscles. 2011 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. pmid:21153644
Lin Y et al. Nucleating effect of calcium stearate coated CaCO(3) nanoparticles on polypropylene. 2011 J Colloid Interface Sci pmid:21122873
Liu H et al. A surfactant-free recipe for shape-controlled synthesis of CdSe nanocrystals. 2011 Nanotechnology pmid:21169661
de Morais e Silva FA et al. Rosacea fulminans in pregnancy with ocular perforation. 2011 J Dtsch Dermatol Ges pmid:21366860
Morinaga N et al. Synthesis of fatty acid sterol esters using cholesterol esterase from Trichoderma sp. AS59. 2011 Enzyme Microb. Technol. pmid:22113022
Fameau AL et al. Smart foams: switching reversibly between ultrastable and unstable foams. 2011 Angew. Chem. Int. Ed. Engl. pmid:21780260
Li S et al. Preparation, characterization, pharmacokinetics and tissue distribution of solid lipid nanoparticles loaded with tetrandrine. 2011 AAPS PharmSciTech pmid:21811889
Klein CM and Jenkins TC Docosahexaenoic acid elevates trans-18:1 isomers but is not directly converted into trans-18:1 isomers in ruminal batch cultures. 2011 J. Dairy Sci. pmid:21854940
Waters LJ et al. Controlled microwave processing applied to the pharmaceutical formulation of ibuprofen. 2011 AAPS PharmSciTech pmid:21842309
Tuei VC et al. Effects of human serum albumin complexed with free fatty acids on cell viability and insulin secretion in the hamster pancreatic β-cell line HIT-T15. 2011 Life Sci. pmid:21396379
Corvis Y et al. Physicochemical stability of solid dispersions of enantiomeric or racemic ibuprofen in stearic acid. 2011 J Pharm Sci pmid:21905027
Gao Q et al. Synthesis and characterization of novel amphiphilic copolymer stearic acid-coupled F127 nanoparticles for nano-technology based drug delivery system. 2011 Colloids Surf B Biointerfaces pmid:21906917
Khan FN and Dehghan MH Enhanced bioavailability of atorvastatin calcium from stabilized gastric resident formulation. 2011 AAPS PharmSciTech pmid:21879394
Lee DM et al. Oxidative stress and inflammation in renal patients and healthy subjects. 2011 PLoS ONE pmid:21829457
Lipasek RA et al. Effects of anticaking agents and relative humidity on the physical and chemical stability of powdered vitamin C. 2011 J. Food Sci. pmid:22417544
Süntar I et al. Wound Healing Activity of Rubus sanctus Schreber (Rosaceae): Preclinical Study in Animal Models. 2011 Evid Based Complement Alternat Med pmid:19755505
Stingl JC et al. Protocol for minimizing the risk of metachronous adenomas of the colorectum with green tea extract (MIRACLE): a randomised controlled trial of green tea extract versus placebo for nutriprevention of metachronous colon adenomas in the elderly population. 2011 BMC Cancer pmid:21851602
Cheng YY et al. A novel cold-adapted lipase from Sorangium cellulosum strain So0157-2: gene cloning, expression, and enzymatic characterization. 2011 Int J Mol Sci pmid:22072918
Du YZ et al. Quaternary complexes composed of plasmid DNA/protamine/fish sperm DNA/stearic acid grafted chitosan oligosaccharide micelles for gene delivery. 2011 Int. J. Biol. Macromol. pmid:21035503
Peng Q et al. A novel esterase gene cloned from a metagenomic library from neritic sediments of the South China Sea. 2011 Microb. Cell Fact. pmid:22067554
Bhattacharjee A et al. Deposition of stearate-oleate rich seed fat in Mangifera indica is mediated by a FatA type acyl-ACP thioesterase. 2011 Phytochemistry pmid:21130480
Yuan H et al. Stearic acid-g-chitosan polymeric micelle for oral drug delivery: in vitro transport and in vivo absorption. 2011 Mol. Pharm. pmid:21138243
Krogmann A et al. Inflammatory response of human coronary artery endothelial cells to saturated long-chain fatty acids. 2011 Microvasc. Res. pmid:21112343
Pereira MG et al. Trypanosoma cruzi epimastigotes are able to store and mobilize high amounts of cholesterol in reservosome lipid inclusions. 2011 PLoS ONE pmid:21818313
Sloat BR et al. In vitro and in vivo anti-tumor activities of a gemcitabine derivative carried by nanoparticles. 2011 Int J Pharm pmid:21371545