MeSH term | MeSH ID | Detail |
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Abortion, Spontaneous | D000022 | 12 associated lipids |
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Morita YS and Englund PT | Fatty acid remodeling of glycosyl phosphatidylinositol anchors in Trypanosoma brucei: incorporation of fatty acids other than myristate. | 2001 | Mol. Biochem. Parasitol. | pmid:11420102 |
Liang X et al. | Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction. | 2001 | J. Biol. Chem. | pmid:11423543 |
Kim JY et al. | Lipid and fatty acid analysis of fresh and frozen-thawed immature and in vitro matured bovine oocytes. | 2001 | Reproduction | pmid:11425337 |
Radwan SS et al. | Effects of lipids on n-alkane attenuation in media supporting oil-utilizing microorganisms from the oily Arabian Gulf coasts. | 2001 | FEMS Microbiol. Lett. | pmid:11430415 |
Hilpert B et al. | Isolation and characterization of signal transduction mutants of Arabidopsis thaliana that constitutively activate the octadecanoid pathway and form necrotic microlesions. | 2001 | Plant J. | pmid:11439130 |
Thompson GE and Darling KF | The hepatic uptake of individual free fatty acids in sheep during noradrenaline infusion. | 1975 | Res. Vet. Sci. | pmid:1144925 |
Mu YM et al. | Saturated FFAs, palmitic acid and stearic acid, induce apoptosis in human granulosa cells. | 2001 | Endocrinology | pmid:11459807 |
Lalman JA and Bagley DM | Anaerobic degradation and methanogenic inhibitory effects of oleic and stearic acids. | 2001 | Water Res. | pmid:11471698 |
Gupta SV and Khosla P | Palmitic and stearic acids similarly affect plasma lipoprotein metabolism in cynomolgus monkeys fed diets with adequate levels of linoleic acid. | 2001 | J. Nutr. | pmid:11481404 |
Choo CY et al. | The cytotoxicity and chemical constituents of the hexane fraction of Typhonium flagelliforme (Araceace). | 2001 | J Ethnopharmacol | pmid:11483390 |