MeSH term | MeSH ID | Detail |
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Abortion, Spontaneous | D000022 | 12 associated lipids |
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Gonzalez-Castro MY et al. | Effects of blanching, freezing and freeze-drying on the fatty acid contents of green beans. | 1996 | Z Lebensm Unters Forsch | pmid:9123974 |
Aro A et al. | Stearic acid, trans fatty acids, and dairy fat: effects on serum and lipoprotein lipids, apolipoproteins, lipoprotein(a), and lipid transfer proteins in healthy subjects. | 1997 | Am. J. Clin. Nutr. | pmid:9129471 |
Frohlich BT et al. | Formation and cell-medium partitioning of autoinhibitory free fatty acids and cyclodextrin's effect in the cultivation of Bordetella pertussis. | 1996 | J. Biotechnol. | pmid:9147447 |
Di Pierro D et al. | Separation of representative lipid compounds of biological membranes and lipid derivatives from peroxidized polyunsaturated fatty acids by reversed phase high-performance liquid chromatography. | 1997 | Free Radic. Res. | pmid:9167935 |
Wang H et al. | Apolipoprotein secretion and lipid synthesis: regulation by fatty acids in newborn swine intestinal epithelial cells. | 1997 | Am. J. Physiol. | pmid:9176199 |
Vorum H et al. | Palmitate and stearate binding to human serum albumin. Determination of relative binding constants. | 1997 | J. Pept. Res. | pmid:9176819 |
Fellner V et al. | Effect of nigericin, monensin, and tetronasin on biohydrogenation in continuous flow-through ruminal fermenters. | 1997 | J. Dairy Sci. | pmid:9178132 |
Hassel CA et al. | Dietary stearic acid reduces plasma and hepatic cholesterol concentrations without increasing bile acid excretion in cholesterol-fed hamsters. | 1997 | J. Nutr. | pmid:9187629 |
Williams JP et al. | Regulation of osteoclastic bone resorption by glucose. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9207213 |
Clandinin MT et al. | Omega-3 fatty acid intake results in a relationship between the fatty acid composition of LDL cholesterol ester and LDL cholesterol content in humans. | 1997 | Biochim. Biophys. Acta | pmid:9219909 |