| MeSH term | MeSH ID | Detail |
|---|---|---|
| Decalcification, Pathologic | D003649 | 1 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Decsi T et al. | Trans isomeric octadecenoic acids are related inversely to arachidonic acid and DHA and positively related to mead acid in umbilical vessel wall lipids. | 2002 | Lipids | pmid:12530555 |
| Murakami C et al. | A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride with stearic acid. | 2003 | Biochim. Biophys. Acta | pmid:12535613 |
| Vink BW et al. | A case of rhinolithiasis in botswana: a mineralogical, microscopic and chemical study. | 2002 | J Laryngol Otol | pmid:12537618 |
| Zhang Q et al. | [Retention behavior of solutes on liquid chromatographic column packed with dynamically modified zirconia]. | 1999 | Se Pu | pmid:12549113 |
| Rege PR et al. | Spray-dried chitinosans. Part II: in vitro drug release from tablets made from spray-dried chitinosans. | 2003 | Int J Pharm | pmid:12550780 |
| McDaid FM et al. | Further investigations into the use of high sensitivity differential scanning calorimetry as a means of predicting drug-excipient interactions. | 2003 | Int J Pharm | pmid:12550799 |
| Higashi N and Senoo H | Distribution of vitamin A-storing lipid droplets in hepatic stellate cells in liver lobules--a comparative study. | 2003 | Anat Rec A Discov Mol Cell Evol Biol | pmid:12552640 |
| Heurtault B et al. | The influence of lipid nanocapsule composition on their size distribution. | 2003 | Eur J Pharm Sci | pmid:12554073 |
| Fee JV et al. | Influence of hydrophobic materials on dissolution of a nondisintegrating hydrophilic solid (potassium chloride). | 1976 | J Pharm Sci | pmid:1255446 |
| Alvarez-Lueje A et al. | A selective HPLC method for determination of lercanidipine in tablets. | 2003 | J Pharm Biomed Anal | pmid:12560043 |
| Ulloth JE et al. | Palmitic and stearic fatty acids induce caspase-dependent and -independent cell death in nerve growth factor differentiated PC12 cells. | 2003 | J. Neurochem. | pmid:12562510 |
| Matera M et al. | History of L-carnitine: implications for renal disease. | 2003 | J Ren Nutr | pmid:12563618 |
| Rastogi S et al. | Effect of treatment for Chlamydia trachomatis during pregnancy. | 2003 | Int J Gynaecol Obstet | pmid:12566185 |
| Duan J et al. | [Analysis of ethereal extracts from Odondotermes formosanus and fungus garden]. | 1999 | Zhong Yao Cai | pmid:12571918 |
| Sun X et al. | [Studies on chemical constituents of fat oil of Polygala tenuifolia]. | 2000 | Zhong Yao Cai | pmid:12575116 |
| Begum S et al. | Pentacyclic triterpenoids from the aerial parts of Lantana camara. | 2003 | Chem. Pharm. Bull. | pmid:12576645 |
| Chen DB et al. | [In vitro and in vivo study of two kinds of long-circulating solid lipid nanoparticles containing paclitaxel]. | 2002 | Yao Xue Xue Bao | pmid:12579901 |
| Steinberg FM et al. | Cocoa and chocolate flavonoids: implications for cardiovascular health. | 2003 | J Am Diet Assoc | pmid:12589329 |
| Tsydendambaev VD and Vereshchagin AG | Changes in triacylglycerol composition during ripening of sea buckthorn (Hippophaë rhamnoides L.) seeds. | 2003 | J. Agric. Food Chem. | pmid:12590468 |
| Spencer MM et al. | Mapping the Fas locus controlling stearic acid content in soybean. | 2003 | Theor. Appl. Genet. | pmid:12595989 |