MeSH term | MeSH ID | Detail |
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Decalcification, Pathologic | D003649 | 1 associated lipids |
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Shehab-El-Deen MA et al. | Cryotolerance of bovine blastocysts is affected by oocyte maturation in media containing palmitic or stearic acid. | 2009 | Reprod. Domest. Anim. | pmid:18992093 |
Renaville B et al. | Plasma and follicular fluid fatty acid profiles in dairy cows. | 2010 | Reprod. Domest. Anim. | pmid:19055554 |
Craig OE et al. | Distinguishing wild ruminant lipids by gas chromatography/combustion/isotope ratio mass spectrometry. | 2012 | Rapid Commun. Mass Spectrom. | pmid:22956328 |
Liu Y et al. | Graphene and graphene oxide: two ideal choices for the enrichment and ionization of long-chain fatty acids free from matrix-assisted laser desorption/ionization matrix interference. | 2011 | Rapid Commun. Mass Spectrom. | pmid:22006384 |
Xue R et al. | A serum metabolomic investigation on hepatocellular carcinoma patients by chemical derivatization followed by gas chromatography/mass spectrometry. | 2008 | Rapid Commun. Mass Spectrom. | pmid:18767022 |
Loutelier-Bourhis C et al. | Mechanistic study of maleic anhydride grafting onto fatty double bonds using mass spectrometry. | 2012 | Rapid Commun. Mass Spectrom. | pmid:22555920 |
MIRAS CJ et al. | LIPID BIOSYNTHESIS BY HUMAN BONE MARROW CELL CULTURES AND GAMMA RADIATION. | 1964 | Radiat. Res. | pmid:14201876 |
Yamamoto O | Radiation-induced crosslinks between carboxylic acids and compounds of biological interest. | 1986 | Radiat. Res. | pmid:3952268 |
SNYDER F and WRIGHT R | EFFECT OF LOCALIZED IRRADIATION ON THE METABOLISM OF BONE-MARROW LIPIDS. | 1965 | Radiat. Res. | pmid:14295131 |
Chitapanarux I et al. | Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. | 2010 | Radiat Oncol | pmid:20444243 |