| MeSH term | MeSH ID | Detail |
|---|---|---|
| Edema | D004487 | 152 associated lipids |
| Leukodystrophy, Metachromatic | D007966 | 4 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Foreign Bodies | D005547 | 5 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Uterine Neoplasms | D014594 | 18 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Lymphoma | D008223 | 18 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Drug Hypersensitivity | D004342 | 20 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kumar Gaur P et al. | Nanovesicles of nitrendipine with lipid complex for transdermal delivery: pharmacokinetic and pharmacodynamic studies. | 2016 | Artif Cells Nanomed Biotechnol | pmid:26375758 |
| Li X et al. | Preparation of co-spray dried cushioning agent containing stearic acid for protecting pellet coatings when compressed. | 2016 | Drug Dev Ind Pharm | pmid:26289006 |
| Uğurlu T and Halaçoğlu MD | Effects of hexagonal boron nitride on dry compression mixture of Avicel DG and Starch 1500. | 2016 | Pharm Dev Technol | pmid:25716058 |
| Jójárt I et al. | Study of the compressibility of chewing gum and its applicability as an oral drug delivery system. | 2016 | Pharm Dev Technol | pmid:25673279 |
| Yin L et al. | Benzyl butyl phthalate promotes adipogenesis in 3T3-L1 preadipocytes: A High Content Cellomics and metabolomic analysis. | 2016 | Toxicol In Vitro | pmid:26820058 |
| Guan Q et al. | Docetaxel-Loaded Self-Assembly Stearic Acid-Modified Bletilla striata Polysaccharide Micelles and Their Anticancer Effect: Preparation, Characterization, Cellular Uptake and In Vitro Evaluation. | 2016 | Molecules | pmid:27918445 |
| Shur J et al. | From single excipients to dual excipient platforms in dry powder inhaler products. | 2016 | Int J Pharm | pmid:27262269 |
| Li T et al. | Defense priming by non-jasmonate producing fatty acids in maize (Zea mays). | 2016 | Plant Signal Behav | pmid:27763804 |
| Kanasaki Y et al. | Application of Quartz Crystal Microbalance as a Tool for Detergency Evaluation of Fatty Acid Contamination in Aqueous Systems. | 2016 | J Oleo Sci | pmid:27725481 |
| Simon C et al. | Screening of endocrine activity of compounds migrating from plastic baby bottles using a multi-receptor panel of in vitro bioassays. | 2016 | Toxicol In Vitro | pmid:27633901 |
| Shah RM et al. | Microwave-assisted formulation of solid lipid nanoparticles loaded with non-steroidal anti-inflammatory drugs. | 2016 | Int J Pharm | pmid:27789371 |
| Abreu P et al. | Contractile function recovery in severely injured gastrocnemius muscle of rats treated with either oleic or linoleic acid. | 2016 | Exp. Physiol. | pmid:27579497 |
| Garba L et al. | Heterologous Expression of PA8FAD9 and Functional Characterization of a Δ9-Fatty Acid Desaturase from a Cold-Tolerant Pseudomonas sp. A8. | 2016 | Mol. Biotechnol. | pmid:27629791 |
| Haware RV et al. | Vegetable-derived magnesium stearate functionality evaluation by DM(3) approach. | 2016 | Eur J Pharm Sci | pmid:27108117 |
| Wang HJ et al. | Prolongation of the degradation period and improvement of the angiogenesis of zein porous scaffolds in vivo. | 2016 | J Mater Sci Mater Med | pmid:26979976 |
| Cheng CL et al. | Spectral and morphological classification of different chronic and acute Taiwanese gallstones via FTIR, SEM and ESEM-EDX microanalyses. | 2016 | Dig Liver Dis | pmid:26976784 |
| Moazeni M et al. | Time to overcome fluconazole resistant Candida isolates: Solid lipid nanoparticles as a novel antifungal drug delivery system. | 2016 | Colloids Surf B Biointerfaces | pmid:26974361 |
| Lu H et al. | Elevated circulating stearic acid leads to a major lipotoxic effect on mouse pancreatic beta cells in hyperlipidaemia via a miR-34a-5p-mediated PERK/p53-dependent pathway. | 2016 | Diabetologia | pmid:26969487 |
| Thilakarathna SH et al. | Investigations of in vitro bioaccessibility from interesterified stearic and oleic acid-rich blends. | 2016 | Food Funct | pmid:26961726 |
| Ma F et al. | Improvement of β-TCP/PLLA biodegradable material by surface modification with stearic acid. | 2016 | Mater Sci Eng C Mater Biol Appl | pmid:26952440 |