| MeSH term | MeSH ID | Detail |
|---|---|---|
| Edema | D004487 | 152 associated lipids |
| Leukodystrophy, Metachromatic | D007966 | 4 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Foreign Bodies | D005547 | 5 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Uterine Neoplasms | D014594 | 18 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Lymphoma | D008223 | 18 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Drug Hypersensitivity | D004342 | 20 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ruddle P et al. | Effect of a novel mutation in a Δ9-stearoyl-ACP-desaturase on soybean seed oil composition. | 2013 | Theor. Appl. Genet. | pmid:22961205 |
| Chu X et al. | Sterol regulatory element-binding protein-1c mediates increase of postprandial stearic acid, a potential target for improving insulin resistance, in hyperlipidemia. | 2013 | Diabetes | pmid:22966071 |
| Němcová-Fürstová V et al. | Caspase-2 and JNK activated by saturated fatty acids are not involved in apoptosis induction but modulate ER stress in human pancreatic β-cells. | 2013 | Cell. Physiol. Biochem. | pmid:23466956 |
| Sovány T et al. | Application of physicochemical properties and process parameters in the development of a neural network model for prediction of tablet characteristics. | 2013 | AAPS PharmSciTech | pmid:23413109 |
| Mirani ZA and Jamil N | Role of extra-cellular fatty acids in vancomycin induced biofilm formation by vancomycin resistant Staphylococcus aureus. | 2013 | Pak J Pharm Sci | pmid:23455211 |
| Franc A et al. | [Content uniformity of warfarin-containing mixtures and tablets]. | 2013 | Ceska Slov Farm | pmid:24047147 |
| MužÃková J and Sináglová P | A study of a new co-processed dry binder based on spray-dried lactose and microcrystalline cellulose. | 2013 | Ceska Slov Farm | pmid:23961814 |
| Ogata F et al. | Study on analysis of waste edible oil with deterioration and removal of acid value, carbonyl value, and free fatty acid by a food additive (calcium silicate). | 2013 | J Oleo Sci | pmid:23391535 |
| Ishida Y et al. | Fatty acid solubilizer from the oral disk of the blowfly. | 2013 | PLoS ONE | pmid:23326317 |
| Sharma P et al. | Structural insights into the dual strategy of recognition by peptidoglycan recognition protein, PGRP-S: structure of the ternary complex of PGRP-S with lipopolysaccharide and stearic acid. | 2013 | PLoS ONE | pmid:23326499 |
| Tükel S et al. | Optimization of lipase-catalyzed synthesis of fructose stearate using response surface methodology. | 2013 | Artif Cells Nanomed Biotechnol | pmid:23305558 |
| Avalle P et al. | Interrogating erosion-based drug liberation phenomena from hydrophilic matrices using near infrared (NIR) spectroscopy. | 2013 | Eur J Pharm Sci | pmid:23059372 |
| Desai SS et al. | Methods for reduction of cohesive forces between carrier and drug in DPI formulation. | 2013 | Drug Dev Ind Pharm | pmid:23050727 |
| Vijayaraghavan M et al. | Suitability of polymer materials for production of pulmonary microparticles using a PGSS supercritical fluid technique: preparation of microparticles using PEG, fatty acids and physical or chemicals blends of PEG and fatty acids. | 2013 | Int J Pharm | pmid:23178217 |
| Uchimoto T et al. | Determination of useful ranges of mixing conditions for glycerin Fatty Acid ester by multiple regression analysis. | 2013 | Chem. Pharm. Bull. | pmid:24189302 |
| Tsuchiya A et al. | Stearic acid serves as a potent inhibitor of protein tyrosine phosphatase 1B. | 2013 | Cell. Physiol. Biochem. | pmid:24296476 |
| Camacho-Chab JC et al. | Emulsifying activity and stability of a non-toxic bioemulsifier synthesized by Microbacterium sp. MC3B-10. | 2013 | Int J Mol Sci | pmid:24065097 |
| Šašiċ S et al. | Raman chemical mapping of magnesium stearate delivered by a punch-face lubrication system on the surface of placebo and active tablets. | 2013 | Appl Spectrosc | pmid:24067639 |
| Tammaro A et al. | Magnesium stearate: an underestimated allergen. | 2012 Oct-Dec | J. Biol. Regul. Homeost. Agents | pmid:23241129 |
| Hentzschel CM et al. | Comparison of traditional and novel tableting excipients: physical and compaction properties. | 2012 Nov-Dec | Pharm Dev Technol | pmid:21740091 |
| Khan FN and Dehghan MH | Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives. | 2012 Jan-Mar | Sci Pharm | pmid:22396916 |
| Pujeri SS et al. | Stress degradation studies on varenicline tartrate and development of a validated stability-indicating HPLC method. | 2012 Jan-Mar | Sci Pharm | pmid:22396908 |
| Liu X et al. | Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming. | 2012 | PLoS Pathog. | pmid:22412372 |
| Lee AL and Kim CB | The effect of erythromycin on gastrointestinal motility in subtotal gastrectomized patients. | 2012 | J Korean Surg Soc | pmid:22403748 |
| Sampey BP et al. | Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. | 2012 | PLoS ONE | pmid:22701716 |
| Wolańska D and Kłosiewicz-Latoszek L | [Fatty acids intake and serum lipids profile in overweighted and obese adults]. | 2012 | Rocz Panstw Zakl Hig | pmid:22928362 |
| Craig OE et al. | Distinguishing wild ruminant lipids by gas chromatography/combustion/isotope ratio mass spectrometry. | 2012 | Rapid Commun. Mass Spectrom. | pmid:22956328 |
| Ahn J et al. | Lycopene inhibits hepatic steatosis via microRNA-21-induced downregulation of fatty acid-binding protein 7 in mice fed a high-fat diet. | 2012 | Mol Nutr Food Res | pmid:22968990 |
| Basseri S and Austin RC | Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential. | 2012 | Biochem Res Int | pmid:22195283 |
| Seeliger JC et al. | Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis. | 2012 | J. Biol. Chem. | pmid:22194604 |
| Chansela P et al. | Composition and localization of lipids in Penaeus merguiensis ovaries during the ovarian maturation cycle as revealed by imaging mass spectrometry. | 2012 | PLoS ONE | pmid:22432001 |
| Gröblacher B et al. | Compounds of Alpinia katsumadai as potential efflux inhibitors in Mycobacterium smegmatis. | 2012 | Bioorg. Med. Chem. | pmid:22459211 |
| Nakagawa H et al. | Evaluation of infrared-reflection absorption spectroscopy measurement and locally weighted partial least-squares for rapid analysis of residual drug substances in cleaning processes. | 2012 | Anal. Chem. | pmid:22449097 |
| Ménard N et al. | Novel surfactants with diglutamic acid polar head group: drug solubilization and toxicity studies. | 2012 | Pharm. Res. | pmid:22451248 |
| Taveira SF et al. | Development of cationic solid lipid nanoparticles with factorial design-based studies for topical administration of doxorubicin. | 2012 | J Biomed Nanotechnol | pmid:22515073 |
| Kakisaka K et al. | Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis. | 2012 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:21995961 |
| Galvao TF et al. | High intake of saturated fat, but not polyunsaturated fat, improves survival in heart failure despite persistent mitochondrial defects. | 2012 | Cardiovasc. Res. | pmid:21960686 |
| Serra Bonvehi J and Orantes Bermejo FJ | Detection of adulterated commercial Spanish beeswax. | 2012 | Food Chem | pmid:26434344 |
| Lou CW et al. | PLA/ β-TCP complex tubes: the mechanical properties and applications of artificial bone. | 2012 | J Biomater Sci Polym Ed | pmid:21968651 |
| Varshosaz J et al. | Optimization of self-assembling properties of fatty acids grafted to methoxy poly(ethylene glycol) as nanocarriers for etoposide. | 2012 | Acta Pharm | pmid:22472447 |
| Hu SY et al. | [Studies on sustained release solid dispersion of tripterine carried by HPMC-stearic acid]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:23311152 |
| Lee SH et al. | End point determination of blending process for trimebutine tablets using principle component analysis (PCA) and partial least squares (PLS) regression. | 2012 | Arch. Pharm. Res. | pmid:23054717 |
| Osmond G et al. | Metal stearate distributions in modern artists' oil paints: surface and cross-sectional investigation of reference paint films using conventional and synchrotron infrared microspectroscopy. | 2012 | Appl Spectrosc | pmid:23031696 |
| McNamee CE et al. | Effect of the degree of dissociation of molecules in a monolayer at an air/water interface on the force between the monolayer and a like-charged particle in the subphase. | 2012 | J Phys Chem B | pmid:23092192 |
| Sharma P et al. | Synthesis of cytarabine lipid drug conjugate for treatment of meningeal leukemia: development, characterization and in vitro cell line studies. | 2012 | J Biomed Nanotechnol | pmid:23030001 |
| Charpentier PA et al. | Nano-TiO2/polyurethane composites for antibacterial and self-cleaning coatings. | 2012 | Nanotechnology | pmid:23037881 |
| Baldwin AC et al. | A role for aberrant protein palmitoylation in FFA-induced ER stress and β-cell death. | 2012 | Am. J. Physiol. Endocrinol. Metab. | pmid:22436701 |
| Wang X et al. | Volatile components of ethanolic extract from broccolini leaves. | 2012 | Nat. Prod. Res. | pmid:21859369 |
| Dawes J et al. | An investigation into the impact of magnesium stearate on powder feeding during roller compaction. | 2012 | Drug Dev Ind Pharm | pmid:21810064 |
| Smathers RL et al. | Characterization of 4-HNE modified L-FABP reveals alterations in structural and functional dynamics. | 2012 | PLoS ONE | pmid:22701647 |