stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Maddux MS et al. | The effect of erythromycin on theophylline pharmacokinetics at steady state. | 1982 | Chest | pmid:7042226 |
Aprahamian SA et al. | Comparative studies on the kinetic parameters and product analyses of chicken and rat liver and yeast fatty acid synthetase. | 1982 | Comp. Biochem. Physiol., B | pmid:7044669 |
Jacques NA | Relationship between cyclopropane synthetase and the formation of cyclopropane fatty acids by Proteus vulgaris grown under various respiratory conditions. | 1982 | J. Gen. Microbiol. | pmid:7045282 |
Wei TC | Quantitative determination of chemical composition of gallstones by infrared absorption spectrophotometry. | 1982 | Taiwan Yi Xue Hui Za Zhi | pmid:6954245 |
Slomiany BL et al. | Lipid composition of the matrix of human submandibular salivary gland stones. | 1982 | Arch. Oral Biol. | pmid:6958224 |
Tinsley IJ et al. | Tissue fatty acid changes and tumor incidence in C3H mice ingesting cottonseed oil. | 1982 | Lipids | pmid:6896358 |
Goto M et al. | Evidence for a correlation between swimming velocity and membrane fluidity of Tetrahymena cells. | 1982 | Biochim. Biophys. Acta | pmid:6818990 |
Moore KH et al. | beta-Hydroxy fatty acid production by ischemic rabbit heart. | 1982 | J. Clin. Invest. | pmid:6799549 |
Hong SL and Deykin D | Activation of phospholipases A2 and C in pig aortic endothelial cells synthesizing prostacyclin. | 1982 | J. Biol. Chem. | pmid:6806265 |
Pharmaceutical Reimbursement Board; final maximum allowable cost (MAC) determinations for certain drug products--Health Care Financing Administration. Final notice. | 1982 | Fed Regist | pmid:10259800 | |
Woodward H et al. | Isolation, purification, and properties of respiratory mucus glycoproteins. | 1982 | Biochemistry | pmid:7074033 |
Katz AM et al. | Fatty acid effects on calcium influx and efflux in sarcoplasmic reticulum vesicles from rabbit skeletal muscle. | 1982 | Biochim. Biophys. Acta | pmid:7074105 |
Bridges CD et al. | Vitamin A in human eyes: amount, distribution, and composition. | 1982 | Invest. Ophthalmol. Vis. Sci. | pmid:7076416 |
Lehmann J and McGill M | Biochemical and ultrastructural alterations in platelets, reticulocytes, and lymphocytes from rats fed vitamin E-deficient diets. | 1982 | J. Lipid Res. | pmid:7077144 |
Josefsson K et al. | Dose-related pharmacokinetics after oral administration of a new formulation of erythromycin base. | 1982 | Br J Clin Pharmacol | pmid:7082537 |
NadtochiÄ VV and BrodskiÄ RA | [Absorption study of 3H-stearic acid in the rat small intestine using electron microscopic autoradiography]. | 1982 | Tsitologiia | pmid:7135486 |
Chen SC et al. | Calorimetric evidence for phase transitions in spin-label lipid bilayers. | 1982 | Biochemistry | pmid:7138849 |
Mroso PV et al. | Solid-state stability of aspirin in the presence of excipients: kinetic interpretation, modeling, and prediction. | 1982 | J Pharm Sci | pmid:7143203 |
Katz AM and Messineo FC | Fatty acid effects on membranes: possible role in the pathogenesis of ischemic myocardial damage. | 1982 | J. Mol. Cell. Cardiol. | pmid:7143451 |
Lerk CF et al. | Interaction of tablet disintegrants and magnesium stearate during mixing. II. Effect on dissolution rate. | 1982 | Pharm Acta Helv | pmid:7146030 |
Warner T and Zar JH | Fatty acid composition of brown fat and brain fat of the little brown bat, Myotis lucifugus, during hibernation. | 1982 | Comp. Biochem. Physiol., B | pmid:7151405 |
Iliopoulou A et al. | Should erythromycin dose be altered in haemodialysis patients? | 1982 | Eur. J. Clin. Pharmacol. | pmid:7151848 |
Bazan NG et al. | High content of 22:6 (docosahexaenoate) and active [2-3H]glycerol metabolism of phosphatidic acid from photoreceptor membranes. | 1982 | Biochim. Biophys. Acta | pmid:6215065 |
May DC et al. | The effects of erythromycin on theophylline elimination in normal males. | 1982 Feb-Mar | J Clin Pharmacol | pmid:7068935 |
della Ventura A and della Ventura D | [Clinical experiments with erythromycin stearate in surgery of the oral cavity]. | 1982 May-Jun | Odontostomatol Implantoprotesi | pmid:6984149 |
Oriel JD et al. | Treatment of gonococcal urethritis in men with a rifampicin-erythromycin combination. | 1982 Oct-Dec | Sex Transm Dis | pmid:6821502 |
Hundrieser KE et al. | Distribution of trans-octadecenoic acid in the major glycerolipids of human milk. | 1983 | J. Pediatr. Gastroenterol. Nutr. | pmid:6644446 |
Hikal AH | Dissolution of meprobamate from various tablet formulations. | 1983 | Pharmazie | pmid:6669616 |
Kohn MC and Garfinkel D | Computer simulation of metabolism in palmitate-perfused rat heart. I. Palmitate oxidation. | 1983 | Ann Biomed Eng | pmid:6592996 |
Duncan MO et al. | Treatment of chancroid with erythromycin. A clinical and microbiological appraisal. | 1983 | Br J Vener Dis | pmid:6603249 |
Upreti GC et al. | Membrane lipids of hepatic tissue. I. Neutral lipids from subcellular fractions of liver and hepatoma 7288CTC. | 1983 | J. Natl. Cancer Inst. | pmid:6572743 |
Erman A et al. | Phospholipase A2 inhibitors. Differential inhibition of fatty acid acylation into kidney lipids by mepacrine and p-bromophenacyl bromide. | 1983 | Biochem. Pharmacol. | pmid:6870935 |
Flood MT et al. | Vitamin A utilization in human retinal pigment epithelial cells in vitro. | 1983 | Invest. Ophthalmol. Vis. Sci. | pmid:6885309 |
Chien JL and Hogan EL | Novel pentahexosyl ganglioside of the globo series purified from chicken muscle. | 1983 | J. Biol. Chem. | pmid:6885798 |
Edwards EK and Edwards EK | Allergic reaction to triethanolamine stearate in a sunscreen. | 1983 | Cutis | pmid:6831931 |
Chapkin RS et al. | Characterization of the individual phospholipids and their fatty acids in serum and high-density lipoprotein of the renal patient on long-term maintenance hemodialysis. | 1983 | J. Lab. Clin. Med. | pmid:6833842 |
Hillmar I et al. | Influence of fatty acids on microsomal diacylglycerol acyltransferase activity in primary cultures of hepatocytes. | 1983 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:6840704 |
Warrell DA et al. | Pathophysiology and immunology of the Jarisch-Herxheimer-like reaction in louse-borne relapsing fever: comparison of tetracycline and slow-release penicillin. | 1983 | J. Infect. Dis. | pmid:6842024 |
Zeisel SH et al. | Formation of methylamines from ingested choline and lecithin. | 1983 | J. Pharmacol. Exp. Ther. | pmid:6842395 |
Foot M et al. | Some properties, including the substrate in vivo, of the delta 9-desaturase in Micrococcus cryophilus. | 1983 | Biochem. J. | pmid:6847622 |
Quinn PA et al. | Efficacy of antibiotic therapy in preventing spontaneous pregnancy loss among couples colonized with genital mycoplasmas. | 1983 | Am. J. Obstet. Gynecol. | pmid:6849358 |
Streichman S et al. | Unique profile for erythrocyte membrane acetylcholinesterase in hereditary spherocytosis. | 1983 | Biochim. Biophys. Acta | pmid:6849970 |
Sobel JD et al. | Legionella bozemanii. Still another cause of pneumonia. | 1983 | JAMA | pmid:6854903 |
Stults BM et al. | Effect of erythromycin stearate on serum theophylline concentration in patients with chronic obstructive lung disease. | 1983 | South. Med. J. | pmid:6857302 |
Slomiany A et al. | Isolation of fatty acids covalently bound to the gastric mucus glycoprotein of normal and cystic fibrosis patients. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6860340 |
Yoshida S et al. | Brain free fatty acids, edema, and mortality in gerbils subjected to transient, bilateral ischemia, and effect of barbiturate anesthesia. | 1983 | J. Neurochem. | pmid:6403669 |
Swendsen CL et al. | 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine: a novel source of arachidonic acid in neutrophils stimulated by the calcium ionophore A23187. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6407484 |
Inman WH and Rawson NS | Erythromycin estolate and jaundice. | 1983 | Br Med J (Clin Res Ed) | pmid:6407653 |
Carli F and Colombo I | Influence of porosity on the contact angle of non-wet solids. | 1983 | J. Pharm. Pharmacol. | pmid:6135790 |
Gabriel SM and Simpkins JW | Effects of a sustained-release naloxone pellet on luteinizing hormone secretion in female rats. | 1983 | Neuroendocrinology | pmid:6139759 |