stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Sheikh KA et al. | Influence of hydration state and homologue composition of magnesium stearate on the physical chemical properties of liquid paraffin lipogels. | 2011 | Int J Pharm | pmid:21457766 |
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Ash MM et al. | Phytosterol stearate esters elicit similar responses on plasma lipids and cholesterol absorption but different responses on fecal neutral sterol excretion and hepatic free cholesterol in male Syrian hamsters. | 2011 | Nutr Res | pmid:21840470 |
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Whitney TR et al. | Redberry juniper as a roughage source in lamb feedlot rations: wool and carcass characteristics, meat fatty acid profiles, and sensory panel traits. | 2011 | Meat Sci. | pmid:21570776 |
Yalcin H et al. | Effect of gamma-irradiation on some chemical characteristics and volatile content of linseed. | 2011 | J Med Food | pmid:21548804 |
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D'Ambrosio DN et al. | Distinct populations of hepatic stellate cells in the mouse liver have different capacities for retinoid and lipid storage. | 2011 | PLoS ONE | pmid:21949825 |
Nurul Syazana MS et al. | Antiproliferative effect of methanolic extraction of tualang honey on human keloid fibroblasts. | 2011 | BMC Complement Altern Med | pmid:21943200 |
Rajpurohit H et al. | Hordeum vulgare hull in the design of fast disintegrating tablets. | 2011 | J Young Pharm | pmid:21897660 |
Tachibana H | Green tea polyphenol sensing. | 2011 | Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. | pmid:21422740 |
Singhal A et al. | Colon-targeted quercetin delivery using natural polymer to enhance its bioavailability. | 2011 | Pharmacognosy Res | pmid:21731393 |
Li FQ et al. | A novel spray-dried nanoparticles-in-microparticles system for formulating scopolamine hydrobromide into orally disintegrating tablets. | 2011 | Int J Nanomedicine | pmid:21720502 |
Eggerath J et al. | EDX-Element Analysis of the In Vitro Effect of Fluoride Oral Hygiene Tablets on Artificial Caries Lesion Formation and Remineralization in Human Enamel. | 2011 | Open Dent J | pmid:21687564 |
Kordyukova LV et al. | Linker and/or transmembrane regions of influenza A/Group-1, A/Group-2, and type B virus hemagglutinins are packed differently within trimers. | 2011 | Biochim. Biophys. Acta | pmid:21420932 |
Wang L et al. | Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations. | 2011 | AIDS Res Ther | pmid:21385339 |
Salem H et al. | Nanosized rods agglomerates as a new approach for formulation of a dry powder inhaler. | 2011 | Int J Nanomedicine | pmid:21383856 |
Intorre F et al. | Differential effect of cheese fatty acid composition on blood lipid profile and redox status in normolipidemic volunteers: a pilot study. | 2011 | Int J Food Sci Nutr | pmid:21591986 |
Gresback R et al. | Combined plasma gas-phase synthesis and colloidal processing of InP/ZnS core/shell nanocrystals. | 2011 | Nanoscale Res Lett | pmid:21711589 |
Desai D et al. | Fatty acid and water-soluble polymer-based controlled release drug delivery system. | 2011 | J Pharm Sci | pmid:21374622 |
Kulinowski P et al. | Magnetic resonance imaging and image analysis for assessment of HPMC matrix tablets structural evolution in USP Apparatus 4. | 2011 | Pharm. Res. | pmid:21181545 |
Christian F et al. | Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes. | 2011 | J. Biol. Chem. | pmid:21177871 |
Su Z et al. | Effect of octreotide-polyethylene glycol(100) monostearate modification on the pharmacokinetics and cellular uptake of nanostructured lipid carrier loaded with hydroxycamptothecine. | 2011 | Mol. Pharm. | pmid:21770405 |
Hayashi Y et al. | Modeling of latent structure of indomethacin solid dispersion tablet using Bayesian networks. | 2011 | Drug Dev Ind Pharm | pmid:21702729 |
Petelska AD and Figaszewski ZA | The equilibria of phosphatidylcholine-fatty acid and phosphatidylcholine-amine in monolayers at the air/water interface. | 2011 | Colloids Surf B Biointerfaces | pmid:20888195 |
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Waters LJ et al. | Controlled microwave processing applied to the pharmaceutical formulation of ibuprofen. | 2011 | AAPS PharmSciTech | pmid:21842309 |
Corvis Y et al. | Physicochemical stability of solid dispersions of enantiomeric or racemic ibuprofen in stearic acid. | 2011 | J Pharm Sci | pmid:21905027 |
Gao Q et al. | Synthesis and characterization of novel amphiphilic copolymer stearic acid-coupled F127 nanoparticles for nano-technology based drug delivery system. | 2011 | Colloids Surf B Biointerfaces | pmid:21906917 |
Khan FN and Dehghan MH | Enhanced bioavailability of atorvastatin calcium from stabilized gastric resident formulation. | 2011 | AAPS PharmSciTech | pmid:21879394 |
Tsai MJ et al. | Oral apomorphine delivery from solid lipid nanoparticles with different monostearate emulsifiers: pharmacokinetic and behavioral evaluations. | 2011 | J Pharm Sci | pmid:20740670 |
Varshosaz J et al. | Lipid nanocapsule-based gels for enhancement of transdermal delivery of ketorolac tromethamine. | 2011 | J Drug Deliv | pmid:22175029 |
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Du YZ et al. | Quaternary complexes composed of plasmid DNA/protamine/fish sperm DNA/stearic acid grafted chitosan oligosaccharide micelles for gene delivery. | 2011 | Int. J. Biol. Macromol. | pmid:21035503 |
Bhattacharjee A et al. | Deposition of stearate-oleate rich seed fat in Mangifera indica is mediated by a FatA type acyl-ACP thioesterase. | 2011 | Phytochemistry | pmid:21130480 |
Bazzini AA et al. | Metabolic and miRNA profiling of TMV infected plants reveals biphasic temporal changes. | 2011 | PLoS ONE | pmid:22174812 |
Göker M et al. | Complete genome sequence of the thermophilic sulfur-reducer Desulfurobacterium thermolithotrophum type strain (BSA(T)) from a deep-sea hydrothermal vent. | 2011 | Stand Genomic Sci | pmid:22675590 |