stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
Related references are published most in these journals:
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Paul D et al. | Proteome and membrane fatty acid analyses on Oligotropha carboxidovorans OM5 grown under chemolithoautotrophic and heterotrophic conditions. | 2011 | PLoS ONE | pmid:21386900 |
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| Rojas J and Kumar V | Comparative evaluation of silicified microcrystalline cellulose II as a direct compression vehicle. | 2011 | Int J Pharm | pmid:21708237 |
| Uchimoto T et al. | A comparative study of glycerin fatty acid ester and magnesium stearate on the dissolution of acetaminophen tablets using the analysis of available surface area. | 2011 | Eur J Pharm Biopharm | pmid:21284955 |
| Subczynski WK et al. | Spin-label oximetry at Q- and W-band. | 2011 | J. Magn. Reson. | pmid:21277814 |
| Potta SG et al. | Preparation and characterization of ibuprofen solid lipid nanoparticles with enhanced solubility. | 2011 | J Microencapsul | pmid:21171818 |
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| Arora G et al. | Formulation and evaluation of controlled release matrix mucoadhesive tablets of domperidone using Salvia plebeian gum. | 2011 | J Adv Pharm Technol Res | pmid:22171313 |
| Sathiyaraj S et al. | Lornoxicam gastro retentive floating matrix tablets: Design and in vitro evaluation. | 2011 | J Adv Pharm Technol Res | pmid:22171312 |
| Solanki SS and Dahima R | Formulation and evaluation of aceclofenac mouth-dissolving tablet. | 2011 | J Adv Pharm Technol Res | pmid:22171305 |
| D'Ambrosio DN et al. | Distinct populations of hepatic stellate cells in the mouse liver have different capacities for retinoid and lipid storage. | 2011 | PLoS ONE | pmid:21949825 |
| Nurul Syazana MS et al. | Antiproliferative effect of methanolic extraction of tualang honey on human keloid fibroblasts. | 2011 | BMC Complement Altern Med | pmid:21943200 |
| Rajpurohit H et al. | Hordeum vulgare hull in the design of fast disintegrating tablets. | 2011 | J Young Pharm | pmid:21897660 |
| Patel D et al. | Design of Controlled Release Non-erodible Polymeric Matrix Tablet Using Microwave Oven-assisted Sintering Technique. | 2011 | J Young Pharm | pmid:21897655 |
| Li FQ et al. | A novel spray-dried nanoparticles-in-microparticles system for formulating scopolamine hydrobromide into orally disintegrating tablets. | 2011 | Int J Nanomedicine | pmid:21720502 |
| Eggerath J et al. | EDX-Element Analysis of the In Vitro Effect of Fluoride Oral Hygiene Tablets on Artificial Caries Lesion Formation and Remineralization in Human Enamel. | 2011 | Open Dent J | pmid:21687564 |
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| Wang L et al. | Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations. | 2011 | AIDS Res Ther | pmid:21385339 |
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| Nicholls HT et al. | Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue. | 2011 | Diabetes | pmid:21378177 |
| Meng Y et al. | Two-step synthesis of fatty acid ethyl ester from soybean oil catalyzed by Yarrowia lipolytica lipase. | 2011 | Biotechnol Biofuels | pmid:21366905 |
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| Christian F et al. | Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes. | 2011 | J. Biol. Chem. | pmid:21177871 |
| Gallardo LA et al. | Europium stearate additives delay oxidation of UHMWPE for orthopaedic applications: a pilot study. | 2011 | Clin. Orthop. Relat. Res. | pmid:21153455 |
| Su Z et al. | Effect of octreotide-polyethylene glycol(100) monostearate modification on the pharmacokinetics and cellular uptake of nanostructured lipid carrier loaded with hydroxycamptothecine. | 2011 | Mol. Pharm. | pmid:21770405 |
| Hayashi Y et al. | Modeling of latent structure of indomethacin solid dispersion tablet using Bayesian networks. | 2011 | Drug Dev Ind Pharm | pmid:21702729 |
| Petelska AD and Figaszewski ZA | The equilibria of phosphatidylcholine-fatty acid and phosphatidylcholine-amine in monolayers at the air/water interface. | 2011 | Colloids Surf B Biointerfaces | pmid:20888195 |
| Laus MN et al. | Activation of the plant mitochondrial potassium channel by free fatty acids and acyl-CoA esters: a possible defence mechanism in the response to hyperosmotic stress. | 2011 | J. Exp. Bot. | pmid:20801915 |
| Roblegg E et al. | Development of sustained-release lipophilic calcium stearate pellets via hot melt extrusion. | 2011 | Eur J Pharm Biopharm | pmid:21801834 |
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| Li Y et al. | Building layer-by-layer 3D supramolecular nanostructures at the terephthalic acid/stearic acid interface. | 2011 | Chem. Commun. (Camb.) | pmid:21755081 |
| Kumar A et al. | Phytochemical investigation and antifeedant activity of Premna latifolia leaves. | 2011 | Nat. Prod. Res. | pmid:21756197 |
| Tsai MJ et al. | Oral apomorphine delivery from solid lipid nanoparticles with different monostearate emulsifiers: pharmacokinetic and behavioral evaluations. | 2011 | J Pharm Sci | pmid:20740670 |
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| Němcová-Fürstová V et al. | Inhibitory effect of unsaturated fatty acids on saturated fatty acid-induced apoptosis in human pancreatic β-cells: activation of caspases and ER stress induction. | 2011 | Cell. Physiol. Biochem. | pmid:21691070 |
| Bazzini AA et al. | Metabolic and miRNA profiling of TMV infected plants reveals biphasic temporal changes. | 2011 | PLoS ONE | pmid:22174812 |
| Xu M et al. | Novel functions of lipid-binding protein 5 in Caenorhabditis elegans fat metabolism. | 2011 | J. Biol. Chem. | pmid:21697096 |
| White HM et al. | Differential regulation of bovine pyruvate carboxylase promoters by fatty acids and peroxisome proliferator-activated receptor-α agonist. | 2011 | J. Dairy Sci. | pmid:21700028 |
| Farboud ES et al. | Novel formulation and evaluation of a Q10-loaded solid lipid nanoparticle cream: in vitro and in vivo studies. | 2011 | Int J Nanomedicine | pmid:21674018 |
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| Göker M et al. | Complete genome sequence of the thermophilic sulfur-reducer Desulfurobacterium thermolithotrophum type strain (BSA(T)) from a deep-sea hydrothermal vent. | 2011 | Stand Genomic Sci | pmid:22675590 |
| Mercado FV et al. | Phase diagram of mixed monolayers of stearic acid and dimyristoylphosphatidylcholine. Effect of the acid ionization. | 2011 | Chem. Phys. Lipids | pmid:21635875 |
| Abbasi M et al. | siRNA-mediated down-regulation of P-glycoprotein in a Xenograft tumor model in NOD-SCID mice. | 2011 | Pharm. Res. | pmid:21638135 |