stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
Related references are published most in these journals:
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What genes are associated with stearic acid?
Related references are published most in these journals:
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen Y et al. | A new method to obtain Fourier transform infrared spectra free from water vapor disturbance. | 2010 | Appl Spectrosc | pmid:20925991 |
| Mukherjee S et al. | Stearic acid delivery to corneum from a mild and moisturizing cleanser. | 2010 | J Cosmet Dermatol | pmid:20883293 |
| Fang X et al. | Development and analysis of an in vivo-compatible metabolic network of Mycobacterium tuberculosis. | 2010 | BMC Syst Biol | pmid:21092312 |
| Rawat MK et al. | Effect of lipid matrix on repaglinide-loaded solid lipid nanoparticles for oral delivery. | 2010 | Ther Deliv | pmid:22816120 |
| Westerbacka J et al. | Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease. | 2010 | Gastroenterology | pmid:20600015 |
| Renaville B et al. | Plasma and follicular fluid fatty acid profiles in dairy cows. | 2010 | Reprod. Domest. Anim. | pmid:19055554 |
| Liu TY and Lin YL | Novel pH-sensitive chitosan-based hydrogel for encapsulating poorly water-soluble drugs. | 2010 | Acta Biomater | pmid:19819354 |
| Rajab M et al. | Optimization of a metformin effervescent floating tablet containing hydroxypropylmethylcellulose and stearic acid. | 2010 | Pharmazie | pmid:20225651 |
| Araújo J et al. | Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications. | 2010 | Int J Pharm | pmid:20362042 |
| Kiss H et al. | Complete genome sequence of Denitrovibrio acetiphilus type strain (N2460). | 2010 | Stand Genomic Sci | pmid:21304711 |
| Bender K et al. | Metabolite concentrations in follicular fluid may explain differences in fertility between heifers and lactating cows. | 2010 | Reproduction | pmid:20385782 |
| Pedersen PJ et al. | Liposomal formulation of retinoids designed for enzyme triggered release. | 2010 | J. Med. Chem. | pmid:20405849 |
| Jain S et al. | Development of a floating dosage form of ranitidine hydrochloride by statistical optimization technique. | 2010 | J Young Pharm | pmid:21264091 |
| Liew CV et al. | In-line quantification of drug and excipients in cohesive powder blends by near infrared spectroscopy. | 2010 | Int J Pharm | pmid:19922776 |
| Naumova EA et al. | Influence of individual saliva secretion on fluoride bioavailability. | 2010 | Open Dent J | pmid:21221176 |
| Patel BP et al. | Formulation and evaluation of mouth dissolving tablets of cinnarizine. | 2010 | Indian J Pharm Sci | pmid:21218071 |
| Sun H et al. | Complete genome sequence of Desulfarculus baarsii type strain (2st14). | 2010 | Stand Genomic Sci | pmid:21304732 |
| Pennick G et al. | Superior effect of isostearyl isostearate on improvement in stratum corneum water permeability barrier function as examined by the plastic occlusion stress test. | 2010 | Int J Cosmet Sci | pmid:20642769 |
| Zhu SH et al. | [Study on the chemical constituents of Dichrocephala integrifolia]. | 2010 | Zhong Yao Cai | pmid:20518304 |
| Wieder DR and Pattimakiel L | Examining the efficacy, safety, and patient acceptability of the combined contraceptive vaginal ring (NuvaRing). | 2010 | Int J Womens Health | pmid:21151688 |
| Manickam E et al. | Suppressive actions of eicosapentaenoic acid on lipid droplet formation in 3T3-L1 adipocytes. | 2010 | Lipids Health Dis | pmid:20525346 |
| Luan L et al. | [Studies on the chemical constituents of extract with water from Forsythia suspensa]. | 2010 | Zhong Yao Cai | pmid:20575415 |
| Remya K et al. | Formulation development, evaluation and comparative study of effects of super disintegrants in cefixime oral disintegrating tablets. | 2010 | J Young Pharm | pmid:21042477 |
| Contreras GA et al. | Lipomobilization in periparturient dairy cows influences the composition of plasma nonesterified fatty acids and leukocyte phospholipid fatty acids. | 2010 | J. Dairy Sci. | pmid:20494158 |
| Sateesha S et al. | Influence of Organic Acids on Diltiazem HCl Release Kinetics from Hydroxypropyl Methyl Cellulose Matrix Tablets. | 2010 | J Young Pharm | pmid:21042476 |
| Karande AD et al. | In-line quantification of micronized drug and excipients in tablets by near infrared (NIR) spectroscopy: Real time monitoring of tabletting process. | 2010 | Int J Pharm | pmid:20558264 |
| Hurko O et al. | Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice. | 2010 | Int J Alzheimers Dis | pmid:20981353 |
| Kim IS and Oh IJ | Preparation and characterization of stearic acid-pullulan nanoparticles. | 2010 | Arch. Pharm. Res. | pmid:20512475 |
| Wang J et al. | Solid-state interactions of a drug substance and excipients and their impact on tablet dissolution: a thermal-mechanical facilitated process-induced transformation or PIT. | 2010 | J Pharm Sci | pmid:20533436 |
| Rao KS and Srinivas K | RP-HPLC Method for the Determination of Losartan Potassium and Ramipril in Combined Dosage Form. | 2010 | Indian J Pharm Sci | pmid:20582199 |
| Keny RV et al. | Formulation and evaluation of rizatriptan benzoate mouth disintegrating tablets. | 2010 | Indian J Pharm Sci | pmid:20582194 |
| Eftaiha AF et al. | Bioadhesive controlled metronidazole release matrix based on chitosan and xanthan gum. | 2010 | Mar Drugs | pmid:20559494 |
| Normand-Lauzière F et al. | Increased postprandial nonesterified fatty acid appearance and oxidation in type 2 diabetes is not fully established in offspring of diabetic subjects. | 2010 | PLoS ONE | pmid:20532041 |
| Rivera CA et al. | Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis. | 2010 | BMC Gastroenterol | pmid:20509914 |
| Barupal DK et al. | Hydrocarbon phenotyping of algal species using pyrolysis-gas chromatography mass spectrometry. | 2010 | BMC Biotechnol. | pmid:20492649 |
| Harvey KA et al. | Oleic acid inhibits stearic acid-induced inhibition of cell growth and pro-inflammatory responses in human aortic endothelial cells. | 2010 | J. Lipid Res. | pmid:20852092 |
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| Saravanakumari P and Mani K | Structural characterization of a novel xylolipid biosurfactant from Lactococcus lactis and analysis of antibacterial activity against multi-drug resistant pathogens. | 2010 | Bioresour. Technol. | pmid:20637606 |
| Invernizzi G et al. | Sustained upregulation of stearoyl-CoA desaturase in bovine mammary tissue with contrasting changes in milk fat synthesis and lipogenic gene networks caused by lipid supplements. | 2010 | Funct. Integr. Genomics | pmid:20607344 |
| Chon B et al. | Shell and ligand-dependent blinking of CdSe-based core/shell nanocrystals. | 2010 | Phys Chem Chem Phys | pmid:20607188 |
| Lin SY et al. | Solid-state transformation of different gabapentin polymorphs upon milling and co-milling. | 2010 | Int J Pharm | pmid:20561572 |
| Bunn RC et al. | Palmitate and insulin synergistically induce IL-6 expression in human monocytes. | 2010 | Cardiovasc Diabetol | pmid:21054880 |
| Asai T and Fujimoto Y | Cyclic fatty acyl glycosides in the glandular trichome exudate of Silene gallica. | 2010 | Phytochemistry | pmid:20541780 |
| Foster SP and Johnson CP | Feeding and hemolymph trehalose concentration influence sex pheromone production in virgin Heliothis virescens moths. | 2010 | J. Insect Physiol. | pmid:20540946 |
| Thörn K and Bergsten P | Fatty acid-induced oxidation and triglyceride formation is higher in insulin-producing MIN6 cells exposed to oleate compared to palmitate. | 2010 | J. Cell. Biochem. | pmid:20524206 |
| Nokhodchi A et al. | Physico-mechanical and dissolution behaviours of ibuprofen crystals crystallized in the presence of various additives. | 2010 | Daru | pmid:22615598 |
| Milanovic J et al. | Microencapsulation of flavors in carnauba wax. | 2010 | Sensors (Basel) | pmid:22315575 |
| Jun HY et al. | Long residence time of ultrasound microbubbles targeted to integrin in murine tumor model. | 2010 | Acad Radiol | pmid:19815430 |
| Lai TY et al. | Alterations in serum fatty acid concentrations and desaturase activities in Bietti crystalline dystrophy unaffected by CYP4V2 genotypes. | 2010 | Invest. Ophthalmol. Vis. Sci. | pmid:19797200 |
| Thomas CP et al. | Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. | 2010 | J. Biol. Chem. | pmid:20061396 |