stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Legrand P and Rioux V | The complex and important cellular and metabolic functions of saturated fatty acids. | 2010 | Lipids | pmid:20625935 |
| Hodson L et al. | Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? | 2010 | Am. J. Physiol. Endocrinol. Metab. | pmid:20628024 |
| Even P et al. | Postprandial effects of a lipid-rich meal in the rat are modulated by the degree of unsaturation of 18C fatty acids. | 2010 | Metab. Clin. Exp. | pmid:19775712 |
| Hirabara SM et al. | Saturated fatty acid-induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells. | 2010 | J. Cell. Physiol. | pmid:19780047 |
| Lehto T et al. | Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy. | 2010 | J Control Release | pmid:19744531 |
| Tay T et al. | Magnesium stearate increases salbutamol sulphate dispersion: what is the mechanism? | 2010 | Int J Pharm | pmid:19748561 |
| Renaville B et al. | Plasma and follicular fluid fatty acid profiles in dairy cows. | 2010 | Reprod. Domest. Anim. | pmid:19055554 |
| Kharia AA et al. | Design and optimization of floating drug delivery system of acyclovir. | 2010 | Indian J Pharm Sci | pmid:21694992 |
| Liu TY and Lin YL | Novel pH-sensitive chitosan-based hydrogel for encapsulating poorly water-soluble drugs. | 2010 | Acta Biomater | pmid:19819354 |
| Elbaz A et al. | Inhibition of fatty acid biosynthesis prevents adipocyte lipotoxicity on human osteoblasts in vitro. | 2010 | J. Cell. Mol. Med. | pmid:19382912 |
| Louis J et al. | PAD4-dependent antibiosis contributes to the ssi2-conferred hyper-resistance to the green peach aphid. | 2010 | Mol. Plant Microbe Interact. | pmid:20367470 |
| Ospina-E JC et al. | Development of combinations of chemically modified vegetable oils as pork backfat substitutes in sausages formulation. | 2010 | Meat Sci. | pmid:20374815 |
| Ye S et al. | Polyunsaturated docosahexaenoic acid suppresses oxidative stress induced endothelial cell calcium influx by altering lipid composition in membrane caveolar rafts. | 2010 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20206488 |
| Rajab M et al. | Optimization of a metformin effervescent floating tablet containing hydroxypropylmethylcellulose and stearic acid. | 2010 | Pharmazie | pmid:20225651 |
| Jeevanandham S et al. | Sustain-release of various drugs from leucaena leucocephala polysaccharide. | 2010 | J Young Pharm | pmid:21331185 |
| Kiss H et al. | Complete genome sequence of Denitrovibrio acetiphilus type strain (N2460). | 2010 | Stand Genomic Sci | pmid:21304711 |
| Muro M et al. | A conformation and orientation model of the carboxylic group of fatty acids dependent on chain length in a Langmuir monolayer film studied by polarization-modulation infrared reflection absorption spectroscopy. | 2010 | J Phys Chem B | pmid:20718412 |
| Sun H et al. | Complete genome sequence of Desulfarculus baarsii type strain (2st14). | 2010 | Stand Genomic Sci | pmid:21304732 |
| Mir VG et al. | Application of crustacean chitin as a co-diluent in direct compression of tablets. | 2010 | AAPS PharmSciTech | pmid:20238188 |
| Pennick G et al. | Superior effect of isostearyl isostearate on improvement in stratum corneum water permeability barrier function as examined by the plastic occlusion stress test. | 2010 | Int J Cosmet Sci | pmid:20642769 |
| Song HJ et al. | Effect of probiotic Lactobacillus (Lacidofil® cap) for the prevention of antibiotic-associated diarrhea: a prospective, randomized, double-blind, multicenter study. | 2010 | J. Korean Med. Sci. | pmid:21165295 |
| Chen JL et al. | Metabolomics of gastric cancer metastasis detected by gas chromatography and mass spectrometry. | 2010 | World J. Gastroenterol. | pmid:21155010 |
| Teixeira AC et al. | Phase behaviour of oleanolic acid, pure and mixed with stearic acid: Interactions and crystallinity. | 2010 | Chem. Phys. Lipids | pmid:20599856 |
| Kajiro H et al. | Flexible two-dimensional square-grid coordination polymers: structures and functions. | 2010 | Int J Mol Sci | pmid:21152303 |
| Borah BM et al. | Surface-modification-directed controlled adsorption of serum albumin onto magnetite nanocuboids synthesized in a gel-diffusion technique. | 2010 | J Colloid Interface Sci | pmid:20621808 |
| Coulon C et al. | Chemical analysis of cellular and extracellular carbohydrates of a biofilm-forming strain Pseudomonas aeruginosa PA14. | 2010 | PLoS ONE | pmid:21151973 |
| Zhu SH et al. | [Study on the chemical constituents of Dichrocephala integrifolia]. | 2010 | Zhong Yao Cai | pmid:20518304 |
| Wieder DR and Pattimakiel L | Examining the efficacy, safety, and patient acceptability of the combined contraceptive vaginal ring (NuvaRing). | 2010 | Int J Womens Health | pmid:21151688 |
| Manickam E et al. | Suppressive actions of eicosapentaenoic acid on lipid droplet formation in 3T3-L1 adipocytes. | 2010 | Lipids Health Dis | pmid:20525346 |
| Kanjanavas P et al. | Purification and characterization of organic solvent and detergent tolerant lipase from thermotolerant Bacillus sp. RN2. | 2010 | Int J Mol Sci | pmid:21152301 |
| Wang Q et al. | One-Step Synthesis of Monodisperse In-Doped ZnO Nanocrystals. | 2010 | Nanoscale Res Lett | pmid:20672040 |
| Pöllänen E et al. | Power training and postmenopausal hormone therapy affect transcriptional control of specific co-regulated gene clusters in skeletal muscle. | 2010 | Age (Dordr) | pmid:20640546 |
| Gentile CL et al. | Fatty acids regulate CREBh via transcriptional mechanisms that are dependent on proteasome activity and insulin. | 2010 | Mol. Cell. Biochem. | pmid:20607591 |
| Bele MH et al. | Effect of Flow Aids on Mucoadhesive Properties of Polymeric Discs of Polyoxyethylene and Carbopol 971P. | 2010 | Indian J Pharm Sci | pmid:20582205 |
| Rao KS and Srinivas K | RP-HPLC Method for the Determination of Losartan Potassium and Ramipril in Combined Dosage Form. | 2010 | Indian J Pharm Sci | pmid:20582199 |
| Keny RV et al. | Formulation and evaluation of rizatriptan benzoate mouth disintegrating tablets. | 2010 | Indian J Pharm Sci | pmid:20582194 |
| Zhou YY et al. | Preparation and pharmacodynamics of stearic acid and poly (lactic-co-glycolic acid) grafted chitosan oligosaccharide micelles for 10-hydroxycamptothecin. | 2010 | Int J Pharm | pmid:20420886 |
| Wu T et al. | Study on superhydrophobic hybrids fabricated from multiwalled carbon nanotubes and stearic acid. | 2010 | J Colloid Interface Sci | pmid:20427047 |
| Li LO et al. | Early hepatic insulin resistance in mice: a metabolomics analysis. | 2010 | Mol. Endocrinol. | pmid:20150186 |
| Tiemeyer S et al. | Effect of surface charge distribution on the adsorption orientation of proteins to lipid monolayers. | 2010 | Langmuir | pmid:20707324 |
| Dasu K et al. | Hydrolysis of fluorotelomer compounds leading to fluorotelomer alcohol production during solvent extractions of soils. | 2010 | Chemosphere | pmid:20801485 |
| Moore F et al. | Improving the hardness of dry granulated tablets containing sodium lauryl sulfate. | 2010 | Int J Pharm | pmid:20801204 |
| Chen X et al. | Plasma metabolomics reveals biomarkers of the atherosclerosis. | 2010 | J Sep Sci | pmid:20730840 |
| Horne I et al. | Two conserved Z9-octadecanoic acid desaturases in the red flour beetle, Tribolium castaneum. | 2010 | Gene | pmid:20709164 |
| Ion G et al. | Maternal consumption of canola oil suppressed mammary gland tumorigenesis in C3(1) TAg mice offspring. | 2010 | BMC Cancer | pmid:20205934 |
| Vlachou M et al. | Utilization of hydrophilic swellable polymers as carriers for sustained drug delivery from matrices and three layer tablet systems. | 2010 | Curr Drug Deliv | pmid:20695845 |
| Mas S et al. | Local non-esterified fatty acids correlate with inflammation in atheroma plaques of patients with type 2 diabetes. | 2010 | Diabetes | pmid:20200316 |
| Walker S et al. | Synthesis, processing and solid state excipient interactions of cucurbit[6]uril and its formulation into tablets for oral drug delivery. | 2010 | Mol. Pharm. | pmid:20669974 |
| Kurian GA et al. | Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts. | 2010 | Chin Med | pmid:20180993 |
| Saravanakumari P and Mani K | Structural characterization of a novel xylolipid biosurfactant from Lactococcus lactis and analysis of antibacterial activity against multi-drug resistant pathogens. | 2010 | Bioresour. Technol. | pmid:20637606 |
| Mathew M et al. | Elevated plasma free fatty acids increase cardiovascular risk by inducing plasma biomarkers of endothelial activation, myeloperoxidase and PAI-1 in healthy subjects. | 2010 | Cardiovasc Diabetol | pmid:20158910 |
| Dong J et al. | Cation-controlled crystal growth of silver stearate: cryo-TEM investigation of lithium vs sodium stearate. | 2010 | Langmuir | pmid:20017506 |
| Fu X et al. | A rapid and universal bacteria-counting approach using CdSe/ZnS/SiO2 composite nanoparticles as fluorescence probe. | 2010 | Anal Bioanal Chem | pmid:20016878 |
| Zhang LJ et al. | Hot-injection synthesis of highly luminescent and monodisperse CdS nanocrystals using thioacetamide and cadmium source with proper reactivity. | 2010 | J Colloid Interface Sci | pmid:19932894 |
| Balani PN et al. | Influence of excipients in comilling on mitigating milling-induced amorphization or structural disorder of crystalline pharmaceutical actives. | 2010 | J Pharm Sci | pmid:19902526 |
| Kuo WT et al. | Polymeric micelles comprising stearic acid-grafted polyethyleneimine as nonviral gene carriers. | 2010 | J Nanosci Nanotechnol | pmid:21133072 |
| Li YW et al. | [Studies on the chemical constituents of Ficus microcarpa]. | 2010 | Zhong Yao Cai | pmid:21049616 |
| Zhang L et al. | Fabrication of nanotubules and microspheres from the self-assembly of amphiphilic monochain stearic acid derivatives. | 2010 | Langmuir | pmid:21049915 |
| Zarbakhsh A et al. | Stabilization of alkylated azacrown ether by fatty acid at the air-water interface. | 2010 | Langmuir | pmid:21049946 |
| Alloatti A et al. | Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. | 2010 | PLoS ONE | pmid:21151902 |
| Alshamsan A et al. | Formulation and delivery of siRNA by oleic acid and stearic acid modified polyethylenimine. | 2009 Jan-Feb | Mol. Pharm. | pmid:19053537 |
| Yuan H et al. | Strategic approaches for improving entrapment of hydrophilic peptide drugs by lipid nanoparticles. | 2009 | Colloids Surf B Biointerfaces | pmid:19185474 |
| Cha D et al. | Analysis of fatty acids in sputum from patients with pulmonary tuberculosis using gas chromatography-mass spectrometry preceded by solid-phase microextraction and post-derivatization on the fiber. | 2009 | J Chromatogr A | pmid:19171347 |
| Mermigkis C et al. | A green oral appliance. | 2009 | Eur. Respir. J. | pmid:19181918 |
| Boros LG et al. | Ethanol diversely alters palmitate, stearate, and oleate metabolism in the liver and pancreas of rats using the deuterium oxide single tracer. | 2009 | Pancreas | pmid:19248221 |
| Ishitsuka Y et al. | Effects of bolus injection of soybean-based fat emulsion and fatty acids on pulmonary gas exchange function. | 2009 | Biol. Pharm. Bull. | pmid:19252304 |
| Pingali KC et al. | Use of a static eliminator to improve powder flow. | 2009 | Int J Pharm | pmid:19266628 |
| Yamamura T et al. | Effects of automated external lubrication on tablet properties and the stability of eprazinone hydrochloride. | 2009 | Int J Pharm | pmid:19059327 |
| Plumley C et al. | Nifedipine nanoparticle agglomeration as a dry powder aerosol formulation strategy. | 2009 | Int J Pharm | pmid:19015016 |
| Burkhardt M et al. | Macroscopic properties and microstructure of HSA based organogels: sensitivity to polar additives. | 2009 | J Colloid Interface Sci | pmid:19144353 |
| Hommelberg PP et al. | Fatty acid-induced NF-kappaB activation and insulin resistance in skeletal muscle are chain length dependent. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:18957619 |
| Gohel M and Bariya SH | Advanced formulation design of venlafaxine hydrochloride coated and triple-layer tablets containing hypromellose. | 2009 | Pharm Dev Technol | pmid:19883254 |
| Chen CY et al. | Chemical constituents from the whole plant of Gaultheria itoana Hayata. | 2009 | Chem. Biodivers. | pmid:19842133 |
| Staiger H et al. | Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans. | 2009 | Diabetes | pmid:19074989 |
| Bao Y et al. | Metabonomic variations in the drug-treated type 2 diabetes mellitus patients and healthy volunteers. | 2009 | J. Proteome Res. | pmid:19714868 |
| Madgulkar AR et al. | Formulation and optimization of sustained release tablets of venlafaxine resinates using response surface methodology. | 2009 | Indian J Pharm Sci | pmid:20502544 |
| Mukherjee S et al. | Solid lipid nanoparticles: a modern formulation approach in drug delivery system. | 2009 | Indian J Pharm Sci | pmid:20502539 |
| Arayne MS et al. | Spectrophotometric Quantitation of Metformin in Bulk Drug and Pharmaceutical Formulations using Multivariate Technique. | 2009 | Indian J Pharm Sci | pmid:20490308 |
| Leonardi R et al. | Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis. | 2009 | J. Biol. Chem. | pmid:19666474 |
| Darwish IA et al. | New spectrophotometric and fluorimetric methods for determination of fluoxetine in pharmaceutical formulations. | 2009 | Int J Anal Chem | pmid:20107560 |
| Darwish IA et al. | Simple spectrophotometric method for determination of paroxetine in tablets using 1,2-naphthoquinone-4-sulphonate as a chromogenic reagent. | 2009 | Int J Anal Chem | pmid:20107559 |
| Guo L and Qing Li G | Olfactory perception of oviposition-deterring fatty acids and their methyl esters by the Asian corn borer, Ostrinia furnacalis. | 2009 | J. Insect Sci. | pmid:20053122 |
| Amorim EA et al. | Effect of cholesterol or cholesteryl conjugates on the cryosurvival of bull sperm. | 2009 | Cryobiology | pmid:19159623 |
| Rittermeier A et al. | The formation of colloidal copper nanoparticles stabilized by zinc stearate: one-pot single-step synthesis and characterization of the core-shell particles. | 2009 | Phys Chem Chem Phys | pmid:19756292 |
| Jiang L et al. | Leptin contributes to the adaptive responses of mice to high-fat diet intake through suppressing the lipogenic pathway. | 2009 | PLoS ONE | pmid:19727392 |
| Lakshmi RV and Basu BJ | Fabrication of superhydrophobic sol-gel composite films using hydrophobically modified colloidal zinc hydroxide. | 2009 | J Colloid Interface Sci | pmid:19720382 |
| Alagna F et al. | Comparative 454 pyrosequencing of transcripts from two olive genotypes during fruit development. | 2009 | BMC Genomics | pmid:19709400 |
| Lozano MM and Longo ML | Microbubbles coated with disaturated lipids and DSPE-PEG2000: phase behavior, collapse transitions, and permeability. | 2009 | Langmuir | pmid:19708150 |
| Spaniol B et al. | Compressional behavior of a mixture of granules containing high load of Phyllanthus niruri spray-dried extract and granules of adjuvants: comparison between eccentric and rotary tablet machines. | 2009 | AAPS PharmSciTech | pmid:19662537 |
| Mukherjee S et al. | Chemistry at air/water interface versus reaction in a flask: tuning molecular conformation in thin films. | 2009 | Langmuir | pmid:19708145 |
| Kantartzis K et al. | Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene. | 2009 | Diabetes | pmid:19651814 |
| Singh R et al. | Mapping quantitative trait loci (QTLs) for fatty acid composition in an interspecific cross of oil palm. | 2009 | BMC Plant Biol. | pmid:19706196 |
| Anderson BM and Ma DW | Are all n-3 polyunsaturated fatty acids created equal? | 2009 | Lipids Health Dis | pmid:19664246 |
| Chin PT et al. | Highly luminescent ultranarrow Mn doped ZnSe nanowires. | 2009 | Nano Lett. | pmid:19146460 |
| Begat P et al. | The role of force control agents in high-dose dry powder inhaler formulations. | 2009 | J Pharm Sci | pmid:19067395 |
| Kaye RS et al. | Development and testing of particulate formulations for the nasal delivery of antibodies. | 2009 | J Control Release | pmid:19059291 |
| Ren X et al. | Nonionic surfactants are strong inhibitors of cytochrome P450 3A biotransformation activity in vitro and in vivo. | 2009 | Eur J Pharm Sci | pmid:19041719 |
| GarcÃa MS et al. | Development of membrane selective electrode for determination of the antipsychotic sulpiride in pharmaceuticals and urine. | 2009 | Sensors (Basel) | pmid:22408528 |
| Rico S et al. | Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines. | 2009 | J Asthma Allergy | pmid:21437146 |
| Chen CJ et al. | Preparation of Monodisperse Iron Oxide Nanoparticles via the Synthesis and Decomposition of Iron Fatty Acid Complexes. | 2009 | Nanoscale Res Lett | pmid:20628451 |